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CA2718306A1 - Variable volume, shape memory actuated insulin dispensing pump - Google Patents

Variable volume, shape memory actuated insulin dispensing pump

Info

Publication number
CA2718306A1
CA2718306A1 CA 2718306 CA2718306A CA2718306A1 CA 2718306 A1 CA2718306 A1 CA 2718306A1 CA 2718306 CA2718306 CA 2718306 CA 2718306 A CA2718306 A CA 2718306A CA 2718306 A1 CA2718306 A1 CA 2718306A1
Authority
CA
Grant status
Application
Patent type
Prior art keywords
pump
position
component
predetermined
shape
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2718306
Other languages
French (fr)
Other versions
CA2718306C (en )
Inventor
Benjamin M. Rush
Christopher V. Reggiardo
Arthur E. Anderson Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Diabetes Care Inc
Original Assignee
Abbott Diabetes Care Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B35/00Piston pumps characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14212Pumping with an aspiration and an expulsion action
    • A61M5/14216Reciprocating piston type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F03MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING WEIGHT AND MISCELLANEOUS MOTORS; PRODUCING MECHANICAL POWER; OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03GSPRING, WEIGHT, INERTIA OR LIKE MOTORS; MECHANICAL-POWER PRODUCING DEVICES OR MECHANISMS, NOT OTHERWISE PROVIDED FOR OR USING ENERGY SOURCES NOT OTHERWISE PROVIDED FOR
    • F03G7/00Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
    • F03G7/06Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like
    • F03G7/065Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like using a shape memory element
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B17/00Pumps characterised by combination with, or adaptation to, specific driving engines or motors
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B23/00Pumping installations or systems
    • F04B23/02Pumping installations or systems having reservoirs
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B35/00Piston pumps characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for
    • F04B35/04Piston pumps characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for the means being electric
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/06Control using electricity
    • F04B49/065Control using electricity and making use of computers
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B9/00Piston machines or pumps characterised by the driving or driven means to or from their working members
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B9/00Piston machines or pumps characterised by the driving or driven means to or from their working members
    • F04B9/02Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00Apparatus requiring external operation and adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container without regard to weight and to deliver it
    • G01F11/02Apparatus requiring external operation and adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container without regard to weight and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/021Apparatus requiring external operation and adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container without regard to weight and to deliver it with measuring chambers which expand or contract during measurement of the piston type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266Shape memory materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0272Electro-active or magneto-active materials
    • A61M2205/0288Electro-rheological or magneto-rheological materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3317Electromagnetic, inductive or dielectric measuring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/70General characteristics of the apparatus with testing or calibration facilities
    • A61M2205/702General characteristics of the apparatus with testing or calibration facilities automatically during use
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2201/00Pump parameters
    • F04B2201/02Piston parameters
    • F04B2201/0201Position of the piston
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F05INDEXING SCHEMES RELATING TO ENGINES OR PUMPS IN VARIOUS SUBCLASSES OF CLASSES F01-F04
    • F05CINDEXING SCHEME RELATING TO MATERIALS, MATERIAL PROPERTIES OR MATERIAL CHARACTERISTICS FOR MACHINES, ENGINES OR PUMPS OTHER THAN NON-POSITIVE-DISPLACEMENT MACHINES OR ENGINES
    • F05C2251/00Material properties
    • F05C2251/08Shape memory

Abstract

A portable pumping system provides insulin or other drugs to a user. A shape memory element is used to actuate the pump and an intelligent system controls the actuator in order to minimize stresses within the system and provide accurate and reliable dosage delivery. The control system utilizes various types of feedback to monitor and optimize the position of the pumping mechanisms.
Physical design aspects also minimize stress and the combination of the physical design aspects and the intelligent operation of the system results in a lightweight and cost effective pump that may be used in a disposable fashion if desired.

Claims (25)

1. A method of pumping a liquid, comprising:
applying at least one electrical pulse to a shape memory alloy to overcome a bias force of a first spring coupled to the shape memory alloy to move a piston by a predetermined distance, the piston movement corresponding to a pumping cycle;
detecting a stressed state of the shape memory alloy resulting from the shape memory alloy overcoming a bias force of a second spring coupled to the shape memory alloy;
detecting an occlusion by monitoring a rate of change of a position of the piston over a time period using an encoding grid disposed on the piston and comparing the monitored rate of change of the position of the piston to a predetermined rate of change of the position of the piston over the time period, wherein the predetermined rate of change of the position of the piston is based, at least in part, on the at least one electrical pulse applied to the shape memory alloy; and modifying the at least one electrical pulse when at least one of the stressed state is detected or the occlusion is detected.
2. The method of claim 1, further comprising determining a position of the piston using the encoding grid and comparing the determined position to a predetermined position, wherein the predetermined position is associated with the pumping cycle.
3. The method of claim 2, wherein comparing the monitored position of the piston to the predetermined position includes determining whether the pumping cycle has completed.
4. The method of claim 3, wherein the occlusion is detected when the pumping cycle has not completed.
5. The method of claim 2, wherein the pumping cycle includes movement of a predetermined dose of fluid.
6. The method of claim 5, wherein the fluid includes insulin.
7. The method of claim 2, wherein determining a position of the piston using an encoding grid comprises measuring the capacitance between a stationary conductive element and a conductive portion of the encoding grid.
8. The method of claim 1 wherein the encoding grid comprises a plurality of conductive portions and nonconductive portions and wherein each of the plurality of conductive portions and nonconductive portions are arranged in a plurality of patterns on the grid to indicate a plurality of positions of the piston.
9. The method of claim 1, including generating an output signal when the occlusion is detected.
10. The method of claim 9, including providing the output signal to a display.
11. The method of claim 1, wherein a spring constant of the second spring is greater than a spring constant of the first spring.
12. The method of claim 1, wherein modifying the at least one electrical pulse when the stress state is detected includes reducing a level of the at least one electrical pulse to prevent the stress state from occurring:
13. An apparatus, comprising:
a pump component;
a microprocessor; and a drive circuit operatively coupled to the microprocessor and the pump component, the drive circuit including a shape memory alloy operatively coupled to the pump component and configured to move the pump component in a predetermined direction, the drive circuit further including a first spring coupled to the shape memory alloy and the pump component, and a second spring coupled to the shape memory alloy;

wherein the microprocessor is configured to:

control the drive circuit to apply at least one electrical pulse to the shape memory alloy to overcome a bias force of the first spring to move the pump component by a predetermined distance, the movement of the pump component corresponding to a pump cycle;
detect a stressed state of the shape memory alloy resulting from the shape memory alloy overcoming a bias force of the second spring;
detect an occlusion by monitoring a rate of change of a position of the pump component over a time period using an encoding grid disposed on the pump component and comparing the monitored rate of change of the pump component to a predetermined rate of change of the position of the pump component over the time period, wherein the predetermined rate of change of the position of the pump component is based, at least in part, on the at least one electrical pulse applied to the shape memory alloy; and modify the at least one electrical pulse when at least one of the stressed state is detected or the occlusion is detected.
14. The apparatus of claim 13, wherein the microprocessor is configured to determine a position of the pump component using the encoding grid and compare the determined position of the pump component to a predetermined position, wherein the predetermined position is associated with the pump cycle.
15. The apparatus of claim 14, wherein determining a position of the pump component using an encoding grid comprises measuring the capacitance between a stationary conductive element and a conductive portion of the encoding grid.
16. The apparatus of claim 14, wherein the microprocessor determines whether the pump cycle has completed.
17. The apparatus of claim 14, wherein the microprocessor detects the occlusion when the pump cycle has not completed.
18. The apparatus of claim 14, wherein the pump cycle includes movement of a predetermined dose of fluid.
19. The apparatus of claim 18, wherein the fluid includes insulin.
20. The apparatus of claim 13, wherein the microprocessor is configured to generate an output signal when the occlusion is detected.
21. The apparatus of claim 20, including a display configured to output the generated output signal.
22. The apparatus of claim 13, wherein the predetermined direction includes a first direction and a second direction, wherein one of the first direction or the second direction is associated with a direction of fluid delivery.
23. The apparatus of claim 13, wherein a spring constant of the second spring is greater than a spring constant of the first spring.
24. The apparatus of claim 13, wherein the encoding grid comprises a plurality of conductive portions and nonconductive portions and wherein each of the plurality of conductive portions and nonconductive portions are arranged in a plurality of patterns on the grid to indicate a plurality of positions of the pump component.
25. The apparatus of claim 13, wherein modifying the at least one electrical pulse when the stress state is detected includes causing the microprocessor to reduce a level of the at least one electrical pulse to prevent the stress state from occurring.
CA 2718306 2002-10-09 2006-04-13 Variable volume, shape memory actuated insulin dispensing pump Active CA2718306C (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US11/106,155 2005-04-13
US11106155 US7993108B2 (en) 2002-10-09 2005-04-13 Variable volume, shape memory actuated insulin dispensing pump
CA 2604498 CA2604498C (en) 2005-04-13 2006-04-13 Variable volume, shape memory actuated insulin dispensing pump

Publications (2)

Publication Number Publication Date
CA2718306A1 true true CA2718306A1 (en) 2006-10-26
CA2718306C CA2718306C (en) 2012-09-04

Family

ID=37115768

Family Applications (2)

Application Number Title Priority Date Filing Date
CA 2604498 Active CA2604498C (en) 2002-10-09 2006-04-13 Variable volume, shape memory actuated insulin dispensing pump
CA 2718306 Active CA2718306C (en) 2002-10-09 2006-04-13 Variable volume, shape memory actuated insulin dispensing pump

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA 2604498 Active CA2604498C (en) 2002-10-09 2006-04-13 Variable volume, shape memory actuated insulin dispensing pump

Country Status (5)

Country Link
US (7) US7993108B2 (en)
EP (1) EP1877662A4 (en)
CN (1) CN101189431B (en)
CA (2) CA2604498C (en)
WO (1) WO2006113521A3 (en)

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