CA2623795C - Methods and constructs for analyzing biological activities of biological specimens and determining states of organism - Google Patents

Methods and constructs for analyzing biological activities of biological specimens and determining states of organism Download PDF

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Publication number
CA2623795C
CA2623795C CA2623795A CA2623795A CA2623795C CA 2623795 C CA2623795 C CA 2623795C CA 2623795 A CA2623795 A CA 2623795A CA 2623795 A CA2623795 A CA 2623795A CA 2623795 C CA2623795 C CA 2623795C
Authority
CA
Canada
Prior art keywords
activities
reporter
cells
cultured
biological sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2623795A
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English (en)
French (fr)
Other versions
CA2623795A1 (en
Inventor
Sergei Romanov
Sergei Makarov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Attagene Inc
Original Assignee
Attagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Attagene Inc filed Critical Attagene Inc
Publication of CA2623795A1 publication Critical patent/CA2623795A1/en
Application granted granted Critical
Publication of CA2623795C publication Critical patent/CA2623795C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2623795A 2005-09-28 2006-09-27 Methods and constructs for analyzing biological activities of biological specimens and determining states of organism Expired - Fee Related CA2623795C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72186005P 2005-09-28 2005-09-28
US60/721,860 2005-09-28
PCT/US2006/038175 WO2007038756A2 (en) 2005-09-28 2006-09-27 Methods and constructs for analyzing biological activities of biological specimens and determining states of organism

Publications (2)

Publication Number Publication Date
CA2623795A1 CA2623795A1 (en) 2007-04-05
CA2623795C true CA2623795C (en) 2016-06-14

Family

ID=37900495

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2623795A Expired - Fee Related CA2623795C (en) 2005-09-28 2006-09-27 Methods and constructs for analyzing biological activities of biological specimens and determining states of organism

Country Status (5)

Country Link
US (1) US20100009348A1 (https=)
EP (1) EP1945795B1 (https=)
JP (1) JP5346583B2 (https=)
CA (1) CA2623795C (https=)
WO (1) WO2007038756A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8924232B2 (en) * 2009-05-11 2014-12-30 Koninklijke Philips N.V. Device and method for comparing molecular signatures
GB201002130D0 (en) * 2010-02-10 2010-03-31 Tmri Ltd Cell based bioassay
US20120245048A1 (en) * 2011-03-25 2012-09-27 Institute For Systems Biology Cellular response assay for biofluid biomarker discovery and detection
EP2748338B1 (en) * 2011-09-08 2017-04-26 Attagene, Inc. Systems and methods for assay of bio-contaminants in water
EP2753708A4 (en) * 2011-09-08 2015-04-22 Attagene Inc SYSTEMS AND METHODS FOR BIOSIMILARITY ASSESSMENT
WO2014121104A1 (en) * 2013-01-31 2014-08-07 The Regents Of The University Of California Pooled genetic perturbation effects
JP2021078370A (ja) * 2019-11-15 2021-05-27 国立大学法人大阪大学 全身性エリトマトーデスの治療薬に対するコンパニオン診断薬
WO2023039392A1 (en) * 2021-09-07 2023-03-16 Mayo Foundation For Medical Education And Research Methods and materials for determining pgc target dosage

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5625048A (en) * 1994-11-10 1997-04-29 The Regents Of The University Of California Modified green fluorescent proteins
CA2252886C (en) * 1996-04-26 2008-02-12 Massachusetts Institute Of Technology Three-hybrid screening assay
AU774183B2 (en) * 1998-12-17 2004-06-17 Xenogen Corporation Non-invasive evaluation of physiological response in a mammal
GB2355791B (en) * 1999-10-28 2004-10-20 Molecular Light Tech Res Ltd Detection of mRNA expression using chemiluminescent labelled probes
US6867348B1 (en) * 1999-12-16 2005-03-15 Xenogen Corporation Methods and compositions for screening for angiogenesis modulating compounds
CA2327581A1 (en) * 2000-12-27 2002-06-27 Yves Blais Methods and compositions for the establishment of genetically altered cell-based library designed for monitoring transcriptional activity of compounds and molecules
US20020177218A1 (en) * 2001-03-30 2002-11-28 Yu Fang Methods of detecting multiple DNA binding protein and DNA interactions in a sample, and devices, systems and kits for practicing the same
US20030037351A1 (en) * 2001-06-06 2003-02-20 Lo Donald C. Nucleic acid regulatory sequences and uses therefor
US20030143547A1 (en) * 2002-01-24 2003-07-31 Xianqiang Li Method for identifying multiple activated transcription factors
US20030148287A1 (en) * 2002-01-24 2003-08-07 Xianqiang Li Libraries and kits for detecting transcription factor activity
DE10211063A1 (de) * 2002-03-13 2003-10-09 Axaron Bioscience Ag Neue Verfahren zur Detektion und Analyse von Protein-Interaktionen in vivo
US20050009052A1 (en) * 2003-04-22 2005-01-13 Irm Llc, A Delaware Limited Liability Company Differential tag length analysis of cell proliferation
US20050181354A1 (en) * 2004-02-18 2005-08-18 Estep Preston W.Iii Methods of assaying physiological states
US7700284B2 (en) * 2004-11-10 2010-04-20 Attagene, Inc. Reporter transcription unit populations and kits comprising same

Also Published As

Publication number Publication date
WO2007038756A3 (en) 2007-07-26
CA2623795A1 (en) 2007-04-05
JP2009509545A (ja) 2009-03-12
JP5346583B2 (ja) 2013-11-20
WO2007038756A9 (en) 2015-10-15
EP1945795B1 (en) 2016-08-10
WO2007038756A2 (en) 2007-04-05
EP1945795A2 (en) 2008-07-23
EP1945795A4 (en) 2010-01-13
US20100009348A1 (en) 2010-01-14

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Effective date: 20210927