CA2541536A1 - Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization (maldi) mass spectrometry (ms) - Google Patents
Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization (maldi) mass spectrometry (ms) Download PDFInfo
- Publication number
- CA2541536A1 CA2541536A1 CA002541536A CA2541536A CA2541536A1 CA 2541536 A1 CA2541536 A1 CA 2541536A1 CA 002541536 A CA002541536 A CA 002541536A CA 2541536 A CA2541536 A CA 2541536A CA 2541536 A1 CA2541536 A1 CA 2541536A1
- Authority
- CA
- Canada
- Prior art keywords
- layer
- capture
- concentrator
- membrane
- porous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
- B01L3/50255—Multi-well filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51161503P | 2003-10-10 | 2003-10-10 | |
| US60/511,615 | 2003-10-10 | ||
| US58184304P | 2004-06-22 | 2004-06-22 | |
| US60/581,843 | 2004-06-22 | ||
| US58609904P | 2004-07-07 | 2004-07-07 | |
| US60/586,099 | 2004-07-07 | ||
| PCT/US2004/033471 WO2005036132A2 (en) | 2003-10-10 | 2004-10-12 | Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization (maldi) mass spectrometry (ms) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2541536A1 true CA2541536A1 (en) | 2005-04-21 |
Family
ID=34437675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002541536A Abandoned CA2541536A1 (en) | 2003-10-10 | 2004-10-12 | Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization (maldi) mass spectrometry (ms) |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7534338B2 (https=) |
| EP (1) | EP1676292A4 (https=) |
| JP (1) | JP2007508552A (https=) |
| CA (1) | CA2541536A1 (https=) |
| WO (1) | WO2005036132A2 (https=) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7095018B2 (en) * | 2004-12-29 | 2006-08-22 | Wisconsin Alumni Research Foundation | Deposition of samples and sample matrix for enhancing the sensitivity of matrix assisted laser desorption/ionization mass spectrometry |
| US7829291B2 (en) * | 2005-02-17 | 2010-11-09 | Vanderbilt University | In situ analysis of tissues |
| US8153435B1 (en) | 2005-03-30 | 2012-04-10 | Tracer Detection Technology Corp. | Methods and articles for identifying objects using encapsulated perfluorocarbon tracers |
| US7109481B1 (en) * | 2005-04-28 | 2006-09-19 | Thermo Finnigan Llc | Matrix-assisted laser desorption and ionization (MALDI) sample plate releasably coupled to a sample plate adapter |
| EP1898799A1 (en) * | 2005-07-06 | 2008-03-19 | Medizinische Universität Graz | Device for and method of delivery and removal of substances in and from a tissue or vessel |
| WO2007046162A1 (ja) * | 2005-10-20 | 2007-04-26 | Japan Science And Technology Agency | 質量分析法に用いられる試料ターゲットおよびその製造方法、並びに当該試料ターゲットを用いた質量分析装置 |
| EP1963480A2 (en) * | 2005-12-08 | 2008-09-03 | Protein Discovery, Inc. | Methods and devices for concentration and fractionation of analytes for chemical analysis |
| JP2007192673A (ja) * | 2006-01-19 | 2007-08-02 | Shimadzu Corp | サンプルプレート |
| KR20090028684A (ko) * | 2006-03-29 | 2009-03-19 | 칸젠 바이오테크날러지즈, 인코포레이티드 | 피크의 검출을 향상시키기 위한 여과용 장치 및 방법 |
| US7858928B2 (en) * | 2006-09-20 | 2010-12-28 | The United States of America Department of Health and Human Services | Nanostructured surfaces as a dual ionization LDI-DESI platform for increased peptide coverage in proteomic analysis |
| US20090071834A1 (en) * | 2007-06-08 | 2009-03-19 | Protein Discovery, Inc. | Methods and Devices for Concentration and Fractionation of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry (MS) |
| WO2010095677A1 (ja) * | 2009-02-18 | 2010-08-26 | 日本電気株式会社 | ターゲットプレートおよびその製造方法 |
| JP2012525591A (ja) * | 2009-04-27 | 2012-10-22 | プロテイン・デイスカバリー・インコーポレーテツド | プログラム可能な電気泳動ノッチフィルターシステムと方法 |
| CA2786412C (en) * | 2010-01-08 | 2018-02-06 | University Of Tasmania | Porous polymer monoliths, processes for preparation and use thereof |
| EP2567395B1 (en) * | 2010-05-07 | 2019-12-18 | UT-Battelle, LLC | System and method for extracting a sample from a surface |
| JP2011242159A (ja) * | 2010-05-14 | 2011-12-01 | Yokohama City Univ | 電気泳動で分離されたタンパク質を膜フィルターに転写し質量分析する方法 |
| US8486703B2 (en) | 2010-09-30 | 2013-07-16 | Ut-Battelle, Llc | Surface sampling concentration and reaction probe |
| US8637813B2 (en) | 2010-10-01 | 2014-01-28 | Ut-Battelle, Llc | System and method for laser assisted sample transfer to solution for chemical analysis |
| US8519330B2 (en) | 2010-10-01 | 2013-08-27 | Ut-Battelle, Llc | Systems and methods for laser assisted sample transfer to solution for chemical analysis |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| US9198609B2 (en) | 2011-04-19 | 2015-12-01 | Porex Corporation | Cards for sample storage and delivery comprising sintered porous plastic |
| WO2013006904A1 (en) | 2011-07-12 | 2013-01-17 | University Of Tasmania | Use of porous polymer materials for storage of biological samples |
| WO2014060483A1 (en) | 2012-10-17 | 2014-04-24 | Spatial Transcriptomics Ab | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| EP3013983B1 (en) | 2013-06-25 | 2023-02-15 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
| JP2016534839A (ja) | 2013-09-16 | 2016-11-10 | ジョンソン・アンド・ジョンソン・イノベーション・エルエルシーJohnson & Johnson Innovation LLC | 境界層分離を組み込む、マイクロ流体器官補助装置 |
| EP3175390A1 (en) | 2014-08-01 | 2017-06-07 | Katholieke Universiteit Leuven | System for interpretation of image patterns in terms of anatomical or curated patterns |
| DE102014114426A1 (de) | 2014-10-06 | 2016-04-07 | Bruker Daltonik Gmbh | MALDI-Träger mit magnetisch gehaltener Federstahlplatte |
| JP6179682B2 (ja) * | 2015-01-22 | 2017-08-16 | 株式会社村田製作所 | 空隙配置構造体およびその製造方法 |
| FR3033409B1 (fr) * | 2015-03-03 | 2017-04-14 | Nicolas Ugolin | Electrodot : procede d'analyse d'echantillons biologiques en matrice de spots fixes par l'action d'un courant electrique conjuguee a une difference de pression |
| US10774374B2 (en) | 2015-04-10 | 2020-09-15 | Spatial Transcriptomics AB and Illumina, Inc. | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| WO2017038709A1 (ja) | 2015-09-03 | 2017-03-09 | 浜松ホトニクス株式会社 | 表面支援レーザ脱離イオン化法、質量分析方法、及び質量分析装置 |
| CN106796198B (zh) * | 2015-09-03 | 2020-06-30 | 浜松光子学株式会社 | 试样支撑体和试样支撑体的制造方法 |
| WO2017053911A1 (en) * | 2015-09-24 | 2017-03-30 | Baird Zane | Mass tag analysis for rare cells and cell free molecules |
| WO2017074934A1 (en) * | 2015-10-28 | 2017-05-04 | Wafergen, Inc. | Single cell capture with capture chips |
| EP3442062A4 (en) * | 2016-04-08 | 2019-12-18 | Idemitsu Kosan Co., Ltd. | BINDING AGENT FOR ELECTROCHEMICAL ELEMENT |
| FR3065652B1 (fr) * | 2017-04-27 | 2021-07-23 | Biomerieux Sa | Plaque d'analyse maldi-tof a support papier et son utilisation |
| WO2019155759A1 (ja) * | 2018-02-09 | 2019-08-15 | 浜松ホトニクス株式会社 | 試料支持体、試料のイオン化方法、及び質量分析方法 |
| JP7217714B2 (ja) | 2018-02-09 | 2023-02-03 | 浜松ホトニクス株式会社 | 試料支持体 |
| US12228480B2 (en) * | 2018-11-30 | 2025-02-18 | Revvity Health Sciences, Inc. | Biological sample preparation using electric fields |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| EP3894590B1 (en) | 2018-12-10 | 2025-10-22 | 10X Genomics, Inc. | Methods of using master / copy arrays for spatial detection |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| JP7227823B2 (ja) * | 2019-03-29 | 2023-02-22 | 浜松ホトニクス株式会社 | 試料支持体 |
| KR102095784B1 (ko) * | 2019-04-26 | 2020-04-01 | 한국과학기술연구원 | 다수표본 마이크로어레이 및 이차이온질량분석기를 이용한 법과학 증거물 감식방법 및 장치 |
| US12157124B2 (en) | 2019-11-06 | 2024-12-03 | 10X Genomics, Inc. | Imaging system hardware |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11768175B1 (en) | 2020-03-04 | 2023-09-26 | 10X Genomics, Inc. | Electrophoretic methods for spatial analysis |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| WO2021252747A1 (en) | 2020-06-10 | 2021-12-16 | 1Ox Genomics, Inc. | Fluid delivery methods |
| EP4491742B1 (en) | 2020-09-18 | 2026-03-04 | 10X Genomics, Inc. | Sample handling apparatus and image registration methods |
| EP4729631A2 (en) | 2020-12-21 | 2026-04-22 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| EP4582555A3 (en) | 2021-06-03 | 2025-10-22 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| CN117501092A (zh) * | 2021-08-02 | 2024-02-02 | 豪夫迈·罗氏有限公司 | 多孔板亲脂性测定 |
| EP4305195A2 (en) | 2021-12-01 | 2024-01-17 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
| EP4441711A1 (en) | 2021-12-20 | 2024-10-09 | 10X Genomics, Inc. | Self-test for pathology/histology slide imaging device |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3271198A (en) * | 1959-12-30 | 1966-09-06 | Ibm | Electrolytic semiconductor photocell |
| US5810989A (en) * | 1997-09-04 | 1998-09-22 | Motorola, Inc. | Photoelectric synthesis of DNA or protein probe arrays |
| US6167910B1 (en) * | 1998-01-20 | 2001-01-02 | Caliper Technologies Corp. | Multi-layer microfluidic devices |
| US6494614B1 (en) * | 1998-07-27 | 2002-12-17 | Battelle Memorial Institute | Laminated microchannel devices, mixing units and method of making same |
| DE60011390T2 (de) | 1999-01-28 | 2004-10-14 | Université De Genève | Verfahren und vorrichtung zur identifikation oder karakterisierung von polypeptiden |
| US20020122747A1 (en) * | 2000-09-19 | 2002-09-05 | Mingqi Zhao | Integrated microdevices for conducting chemical operations |
| US6716629B2 (en) * | 2000-10-10 | 2004-04-06 | Biotrove, Inc. | Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof |
| CA2434699A1 (en) * | 2001-01-17 | 2002-10-17 | Randall W. Nelson | An integrated high throughput system for the analysis of biomolecules |
| US6919046B2 (en) * | 2001-06-07 | 2005-07-19 | Nanostream, Inc. | Microfluidic analytical devices and methods |
| GB0120131D0 (en) * | 2001-08-17 | 2001-10-10 | Micromass Ltd | Maldi target plate |
| GB0122200D0 (en) * | 2001-09-14 | 2001-10-31 | James Peter | Concentration of protein and/or peptide samples |
| US7166441B2 (en) * | 2002-03-12 | 2007-01-23 | Perseptive Biosystems Inc. | Method and apparatus for the identification and quantification of biomolecules |
| US7030373B2 (en) * | 2003-12-19 | 2006-04-18 | Applera Corporation | MALDI plate construction with grid |
-
2004
- 2004-10-12 EP EP04794742A patent/EP1676292A4/en not_active Withdrawn
- 2004-10-12 US US10/963,336 patent/US7534338B2/en not_active Expired - Fee Related
- 2004-10-12 JP JP2006534450A patent/JP2007508552A/ja active Pending
- 2004-10-12 CA CA002541536A patent/CA2541536A1/en not_active Abandoned
- 2004-10-12 WO PCT/US2004/033471 patent/WO2005036132A2/en not_active Ceased
-
2009
- 2009-04-06 US US12/419,126 patent/US20100133098A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7534338B2 (en) | 2009-05-19 |
| WO2005036132A3 (en) | 2006-03-02 |
| EP1676292A4 (en) | 2009-01-07 |
| EP1676292A2 (en) | 2006-07-05 |
| JP2007508552A (ja) | 2007-04-05 |
| US20050116161A1 (en) | 2005-06-02 |
| US20100133098A1 (en) | 2010-06-03 |
| WO2005036132A2 (en) | 2005-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |