CA2494193A1 - Nouveaux lipopeptides immunogenes comprenant des epitopes de lymphocytes t auxiliaires et de lymphocytes t cytotoxiques (ctl) - Google Patents
Nouveaux lipopeptides immunogenes comprenant des epitopes de lymphocytes t auxiliaires et de lymphocytes t cytotoxiques (ctl) Download PDFInfo
- Publication number
- CA2494193A1 CA2494193A1 CA002494193A CA2494193A CA2494193A1 CA 2494193 A1 CA2494193 A1 CA 2494193A1 CA 002494193 A CA002494193 A CA 002494193A CA 2494193 A CA2494193 A CA 2494193A CA 2494193 A1 CA2494193 A1 CA 2494193A1
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- CA
- Canada
- Prior art keywords
- lipopeptide
- epitope
- ctl
- seq
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Abstract
La présente invention concerne des molécules lipopeptidiques immunogènes de synthèse comprenant des épitopes de CTL et de lymphocytes T auxiliaires colinéaires, et des procédés pour les produire et les utiliser dans le cadre de la production de réponses immunitaires primaires et secondaires, et pour vacciner des animaux contre des épitopes de CTL particuliers. L'invention concerne plus particulièrement des lipopeptides hautement solubles, la fraction lipidique étant fixée au groupe de chaîne latérale terminal d'une lysine interne ou d'un analogue à la lysine, de préférence au groupe de chaîne latérale terminal d'un radical diaminoacide interne. De préférence, la lysine interne ou l'analogue à la lysine se trouve entre l'épitope de lymphocyte T auxiliaire et l'épitope de CTL.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40332802P | 2002-08-12 | 2002-08-12 | |
| US60/403,328 | 2002-08-12 | ||
| PCT/AU2003/001019 WO2004014957A1 (fr) | 2002-08-12 | 2003-08-12 | Nouveaux lipopeptides immunogenes comprenant des epitopes de lymphocytes t auxiliaires et de lymphocytes t cytotoxiques (ctl) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2494193A1 true CA2494193A1 (fr) | 2004-02-19 |
Family
ID=31715974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002494193A Abandoned CA2494193A1 (fr) | 2002-08-12 | 2003-08-12 | Nouveaux lipopeptides immunogenes comprenant des epitopes de lymphocytes t auxiliaires et de lymphocytes t cytotoxiques (ctl) |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7833532B2 (fr) |
| EP (2) | EP1546206B1 (fr) |
| JP (2) | JP4619121B2 (fr) |
| KR (1) | KR101151368B1 (fr) |
| CN (2) | CN101113178A (fr) |
| AU (1) | AU2003249778B2 (fr) |
| BR (1) | BR0313101A (fr) |
| CA (1) | CA2494193A1 (fr) |
| ES (1) | ES2535451T3 (fr) |
| WO (1) | WO2004014957A1 (fr) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1755635A4 (fr) * | 2004-05-27 | 2011-04-06 | Novozymes Biopharma Au Ltd | Traitement d'affection inflammatoire des voies respiratoires |
| US20100143405A1 (en) * | 2004-08-26 | 2010-06-10 | David Charles Jackson | Immunotherapy of virus infection |
| US20090105155A1 (en) | 2004-09-10 | 2009-04-23 | David Charles Jackson | Truncated lhrh formulations |
| CN101151020B (zh) * | 2005-02-07 | 2011-09-07 | 利波特卡有限公司 | 佐剂材料 |
| WO2006084319A1 (fr) | 2005-02-08 | 2006-08-17 | The Council Of The Queensland Institute Of Medical Research | Molecules immunogenes |
| CN101448517A (zh) | 2005-04-19 | 2009-06-03 | 伊莱利利公司 | 用于疾病免疫干预的单价和多价合成多糖抗原 |
| CA2660830A1 (fr) | 2006-08-14 | 2008-02-21 | Gideon Goldstein | Compositions et methodes pour le traitement et la prevention d'une infection par de multiples souches et sous-types du vih-1 |
| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| EP2155782A2 (fr) | 2007-03-26 | 2010-02-24 | Dako Denmark A/S | Complexes peptidiques du cmh et leurs utilisations dans des maladies infectieuses |
| CN101066990B (zh) * | 2007-04-27 | 2010-07-07 | 郑州大学 | 具有人群广谱性的抗肿瘤ctl表位肽 |
| EP3620465A1 (fr) | 2007-07-03 | 2020-03-11 | Dako Denmark A/S | Procédés améliorés pour produire, marquer et utiliser des multimères du cmh |
| US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| WO2009046498A1 (fr) | 2007-10-09 | 2009-04-16 | The University Of Melbourne | Procédé de transfection et compositions associées |
| US9138470B2 (en) | 2007-11-02 | 2015-09-22 | The Johns Hopkins University | Multi-component L2 vaccine for prevention of human papilloma virus infection |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| EP2276495B1 (fr) | 2008-04-17 | 2018-11-21 | PDS Biotechnology Corporation | Stimulation de réponse immunitaire par des énantiomères de lipides cationiques |
| EP2320882A4 (fr) * | 2008-07-07 | 2014-12-31 | Univ Melbourne | Composant de vaccin synthétique |
| US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| WO2010037402A1 (fr) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Vaccins moléculaires contre les maladies infectieuses |
| US8969536B2 (en) | 2008-10-16 | 2015-03-03 | Zoetis Llc | Torque teno virus (TTV) isolates and compositions |
| JP2012523379A (ja) | 2009-04-09 | 2012-10-04 | ザ ユニバーシティー オブ メルボルン | 免疫原性組成物およびその使用 |
| DE102009034779A1 (de) | 2009-07-25 | 2011-02-03 | Emc Microcollections Gmbh | Synthetische Analoga bakterieller Lipopeptide und ihre Anwendung zur Therapie und Prophylaxe allergischer Erkrankungen |
| US8846388B2 (en) | 2009-10-16 | 2014-09-30 | Zoetis Llc | Infectious clones of torque teno virus |
| AU2011232421B2 (en) | 2010-03-23 | 2015-08-13 | Novartis Ag | Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc. |
| US9340622B2 (en) * | 2010-09-14 | 2016-05-17 | Council Of Scientific & Industrial Research | Synthetic immunogen useful for generating long lasting immunity and protection against pathogens |
| CA2811957C (fr) | 2010-09-22 | 2019-04-16 | The University Of Melbourne | Fraction de tlr2 soluble destinee au traitement ou a la prevention de maladies respiratoires associees a des agents infectieux |
| DE102011018499A1 (de) | 2011-04-23 | 2012-10-25 | Emc Microcollections Gmbh | Topische Nanopartikel-Vakzine zur Immunstimulation der dendritischen Zellen in der Haut |
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| MY165122A (en) | 2013-06-12 | 2018-02-28 | Maruha Nichiro Corp | Dipeptidyl peptidase-iv (dppiv) inhibitory peptide compound, composition containing the same, and production method for the same |
| CN109893648A (zh) | 2013-06-28 | 2019-06-18 | 奥克兰联合服务有限公司 | 氨基酸缀合物和肽缀合物及缀合方法 |
| KR20170094449A (ko) * | 2014-12-23 | 2017-08-17 | 마가렛 앤 브림블 | 아미노산 및 펩타이드 접합체 및 이들의 용도 |
| EP3108896A1 (fr) * | 2015-06-22 | 2016-12-28 | Jean-Pierre Spinosa | Oligopeptides synthétiques immunogènes |
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| ES2633932B1 (es) * | 2016-02-24 | 2018-07-30 | Fundación Instituto De Investigación Marqués De Valdecilla | Uso de un complejo GNP-LLO91-99 para el tratamiento y la prevención del cáncer. |
| EA201891639A1 (ru) | 2016-02-26 | 2019-06-28 | Окленд Юнисервисес Лимитед | Аминокислотные и пептидные конъюгаты и способ конъюгации |
| US11013798B2 (en) | 2016-03-21 | 2021-05-25 | South Dakota Board Of Regents | Orf virus-based platform for vaccine delivery |
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| AU2019408048A1 (en) * | 2018-12-20 | 2021-06-24 | Universität Zürich | Lipopeptide building blocks and synthetic virus-like particles |
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| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
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| CA2404327A1 (fr) | 2000-03-24 | 2001-09-27 | Biomira, Inc. | Adjuvants lipopeptidiques |
-
2003
- 2003-08-12 WO PCT/AU2003/001019 patent/WO2004014957A1/fr active Application Filing
- 2003-08-12 ES ES03783852.1T patent/ES2535451T3/es not_active Expired - Lifetime
- 2003-08-12 CA CA002494193A patent/CA2494193A1/fr not_active Abandoned
- 2003-08-12 CN CNA2007101118015A patent/CN101113178A/zh active Pending
- 2003-08-12 BR BR0313101-7A patent/BR0313101A/pt not_active IP Right Cessation
- 2003-08-12 US US10/524,936 patent/US7833532B2/en not_active Expired - Fee Related
- 2003-08-12 KR KR1020057002330A patent/KR101151368B1/ko not_active IP Right Cessation
- 2003-08-12 EP EP03783852.1A patent/EP1546206B1/fr not_active Expired - Lifetime
- 2003-08-12 EP EP10011465A patent/EP2314630A1/fr not_active Withdrawn
- 2003-08-12 AU AU2003249778A patent/AU2003249778B2/en not_active Ceased
- 2003-08-12 CN CN038241455A patent/CN1688605B/zh not_active Expired - Fee Related
- 2003-08-12 JP JP2004526518A patent/JP4619121B2/ja not_active Expired - Fee Related
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2009
- 2009-12-28 JP JP2009298173A patent/JP5265512B2/ja not_active Expired - Fee Related
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2010
- 2010-10-08 US US12/901,457 patent/US8986700B2/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| JP2010132663A (ja) | 2010-06-17 |
| AU2003249778A1 (en) | 2004-02-25 |
| JP4619121B2 (ja) | 2011-01-26 |
| CN1688605A (zh) | 2005-10-26 |
| EP2314630A1 (fr) | 2011-04-27 |
| AU2003249778B2 (en) | 2010-09-23 |
| KR20050049472A (ko) | 2005-05-25 |
| EP1546206B1 (fr) | 2014-12-17 |
| US7833532B2 (en) | 2010-11-16 |
| EP1546206A1 (fr) | 2005-06-29 |
| US8986700B2 (en) | 2015-03-24 |
| WO2004014957A1 (fr) | 2004-02-19 |
| EP1546206A4 (fr) | 2007-10-10 |
| BR0313101A (pt) | 2005-06-28 |
| US20070160631A1 (en) | 2007-07-12 |
| US20110280899A1 (en) | 2011-11-17 |
| JP2006513979A (ja) | 2006-04-27 |
| JP5265512B2 (ja) | 2013-08-14 |
| CN101113178A (zh) | 2008-01-30 |
| ES2535451T3 (es) | 2015-05-11 |
| KR101151368B1 (ko) | 2012-06-08 |
| CN1688605B (zh) | 2011-01-12 |
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