CA2490309C - Anthelmintic oral homogeneous veterinary pastes - Google Patents
Anthelmintic oral homogeneous veterinary pastes Download PDFInfo
- Publication number
- CA2490309C CA2490309C CA2490309A CA2490309A CA2490309C CA 2490309 C CA2490309 C CA 2490309C CA 2490309 A CA2490309 A CA 2490309A CA 2490309 A CA2490309 A CA 2490309A CA 2490309 C CA2490309 C CA 2490309C
- Authority
- CA
- Canada
- Prior art keywords
- praziquantel
- ivermectin
- dissolved
- cellulose
- glycerol formal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/177,822 US7001889B2 (en) | 2002-06-21 | 2002-06-21 | Anthelmintic oral homogeneous veterinary pastes |
US10/177,822 | 2002-06-21 | ||
PCT/US2003/019025 WO2004000034A2 (en) | 2002-06-21 | 2003-06-13 | Anthelmintic oral homogeneous veterinary pastes |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2490309A1 CA2490309A1 (en) | 2003-12-31 |
CA2490309C true CA2490309C (en) | 2011-09-27 |
Family
ID=29734505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2490309A Expired - Lifetime CA2490309C (en) | 2002-06-21 | 2003-06-13 | Anthelmintic oral homogeneous veterinary pastes |
Country Status (20)
Country | Link |
---|---|
US (2) | US7001889B2 (es) |
EP (1) | EP1534072B1 (es) |
JP (1) | JP4342440B2 (es) |
AR (1) | AR039722A1 (es) |
AT (1) | ATE390123T1 (es) |
AU (1) | AU2009200336B2 (es) |
BR (1) | BR0312141A (es) |
CA (1) | CA2490309C (es) |
CY (1) | CY1108533T1 (es) |
DE (1) | DE60319996T2 (es) |
DK (1) | DK1534072T3 (es) |
ES (1) | ES2306879T3 (es) |
MA (1) | MA27313A1 (es) |
MX (1) | MXPA05000172A (es) |
NZ (2) | NZ537407A (es) |
PT (1) | PT1534072E (es) |
SI (1) | SI1534072T1 (es) |
TN (1) | TNSN04258A1 (es) |
WO (1) | WO2004000034A2 (es) |
ZA (1) | ZA200410250B (es) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6893652B2 (en) | 2001-08-27 | 2005-05-17 | Wyeth | Endoparasiticidal gel composition |
US7001889B2 (en) * | 2002-06-21 | 2006-02-21 | Merial Limited | Anthelmintic oral homogeneous veterinary pastes |
US20060205681A1 (en) * | 2002-06-21 | 2006-09-14 | Maryam Moaddeb | Homogenous paste formulations |
DK1610613T3 (en) * | 2003-04-04 | 2017-02-27 | Merial Inc | TOPICAL ANTHELMINTIC VETERINARY FORMULATIONS |
ATE534900T1 (de) * | 2003-07-09 | 2011-12-15 | Life Technologies Corp | Verfahren zum testen einer protein-protein- wechselwirkung |
US7396819B2 (en) * | 2003-08-08 | 2008-07-08 | Virbac Corporation | Anthelmintic formulations |
US7671034B2 (en) * | 2003-12-19 | 2010-03-02 | Merial Limited | Stabilized formulation of ivermectin feed premix with an extended shelf life |
DK1566173T3 (da) * | 2004-02-20 | 2006-12-27 | Mattern Udo | Farmaceutisk sammensætning til oral anvendelse og fremgangsmåde til fremstilling deraf |
WO2005094210A2 (en) * | 2004-03-12 | 2005-10-13 | The Hartz Mountain Corporation | Multi-action anthelmintic formulations |
EP2301557A1 (en) * | 2004-09-09 | 2011-03-30 | Warburton Technology Limited | Trace elements |
DE102005011779A1 (de) * | 2005-03-11 | 2006-09-14 | Bayer Healthcare Ag | Endoparasitizide Mittel |
US20080027011A1 (en) * | 2005-12-20 | 2008-01-31 | Hassan Nached | Homogeneous paste and gel formulations |
AU2006100657C4 (en) * | 2006-05-15 | 2009-09-10 | Wyeth | Stabilised formulation |
CA2656617C (en) | 2006-07-05 | 2014-10-14 | Aventis Agriculture | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof |
NZ550279A (en) * | 2006-09-29 | 2008-01-31 | Bomac Research Ltd | Medicament |
ME03373B (me) | 2007-05-15 | 2020-01-20 | Merial Inc | Ariloazol-2-il cijanoetilamino jedinjenja, postupci dobijanja i postupci njihove primene |
AU2008316225B2 (en) | 2007-10-26 | 2014-06-19 | Avivagen Inc. | Compositions and methods for enhancing immune response |
ES2385126T3 (es) * | 2007-11-15 | 2012-07-18 | Novartis Ag | Pasta antihelmíntica que comprende praziquantel, una lactona macrolida, ciclodextrina y un espesante |
NZ590141A (en) * | 2008-06-24 | 2012-05-25 | Merial Ltd | Anthelminthic formulations including castor oil and another vegetable oil |
WO2010022263A2 (en) * | 2008-08-20 | 2010-02-25 | Futurefuel Chemical Company | Process for the preparation of glycerol formal |
MX2009001235A (es) * | 2008-09-19 | 2010-04-29 | Agrovet Market S A | Composicion y uso de un gel oral endoparasiticida bioadhesivo de larga accion a base de doramectina. |
KR101715414B1 (ko) | 2008-11-14 | 2017-03-10 | 메리얼 인코포레이티드 | 거울상 이성질체가 풍부한 아릴로아졸-2-일 시아노에틸아미노 구충 화합물 |
MY155497A (en) | 2008-11-19 | 2015-10-30 | Merial Inc | Compositions comprising an aryl pyrazole and/or a formamidine, methods and use thereof |
US8426460B2 (en) | 2008-12-04 | 2013-04-23 | Merial Limited | Dimeric avermectin and milbemycin derivatives |
TW201041508A (en) * | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity |
CA2771204C (en) | 2009-04-30 | 2017-09-19 | Chemaphor Inc. | Methods and compositions for improving the health of animals |
CN102596968B (zh) | 2009-07-30 | 2015-05-06 | 梅里亚有限公司 | 杀虫的4-氨基-噻吩并[2,3-d]-嘧啶化合物及其使用方法 |
WO2011069143A1 (en) | 2009-12-04 | 2011-06-09 | Merial Limited | Pesticidal bis-organosulfur compounds |
BR112012014933B1 (pt) | 2009-12-17 | 2020-10-27 | Merial, Inc. | composições que compreendem compostos lactonas macrocíclicas e spirodioxepinoindóis |
WO2011075591A1 (en) | 2009-12-17 | 2011-06-23 | Merial Limited | Anti parasitic dihydroazole compounds and compositions comprising same |
UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
SI2640728T1 (sl) | 2010-11-16 | 2017-03-31 | Merial, Inc. | Novi derivati monenzina za zdravljenje in preprečevanje protozojskih infekcij |
WO2013003168A1 (en) | 2011-06-27 | 2013-01-03 | Merial Limited | Novel insect-repellent coumarin derivatives, syntheses, and methods of use |
BR112013033568B1 (pt) | 2011-06-27 | 2020-11-24 | Merial, Inc | Compostos eter amidopiridil e composiqoes, e seu uso contra parasitas |
MX368738B (es) | 2011-11-17 | 2019-10-14 | Boehringer Ingelheim Animal Health Usa Inc | Composiciones que comprenden un aril pirazol y un imidazol sustituido, metodos y usos de las mismas. |
EP2594258B1 (en) | 2011-11-18 | 2020-03-18 | Veterinärmedizinische Universität Wien | Oral gel comprising praziquantel |
EP3351546B9 (en) | 2011-12-02 | 2024-07-10 | Boehringer Ingelheim Vetmedica GmbH | Long-acting injectable moxidectin formulations |
PE20142279A1 (es) * | 2012-03-13 | 2015-01-25 | Bayer New Zealand Ltd | Composiciones de accion prolongada |
EA030814B1 (ru) | 2012-11-20 | 2018-10-31 | Мериал, Инк. | Антигельминтные соединения, композиции и способы их применения |
JP6499970B2 (ja) * | 2013-10-30 | 2019-04-10 | 大蔵製薬株式会社 | 服用し易いゼリー状医薬組成物 |
ES2905848T3 (es) | 2013-11-01 | 2022-04-12 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de isoxazolina antiparasitarios y plaguicidas |
US10045979B2 (en) | 2014-05-19 | 2018-08-14 | Merial Inc. | Anthelmintic compounds |
US10073072B2 (en) | 2014-10-01 | 2018-09-11 | Merial Inc. | Dissolution of hydrophobic API, including avermectins with or without other API such as pyrantel, from a complicated matrix dosage form |
HUE055535T2 (hu) | 2015-05-20 | 2021-12-28 | Boehringer Ingelheim Animal Health Usa Inc | Féreghajtó depszipeptid-vegyületek |
UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
KR102419769B1 (ko) | 2016-08-11 | 2022-07-13 | 아다미스 파마슈티칼스 코포레이션 | 약물 조성물 |
WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
WO2018071535A1 (en) | 2016-10-14 | 2018-04-19 | Merial, Inc. | Pesticidal and parasiticidal vinyl isoxazoline compounds |
CN110167921A (zh) | 2016-11-16 | 2019-08-23 | 勃林格殷格翰动物保健美国公司 | 驱蠕虫缩肽化合物 |
BR112020003217A2 (pt) | 2017-08-14 | 2020-10-06 | Boehringer Ingelheim Animal Health USA Inc. | compostos pesticidas e parasiticidas de pirazolisoxazolina |
RU2681214C1 (ru) * | 2017-10-12 | 2019-03-05 | Федеральное государственное бюджетное научное учреждение "Федеральный научный центр - Всероссийский научно-исследовательский институт экспериментальной ветеринарии имени К.И. Скрябина и Я.Р. Коваленко Российской академии наук | Способ получения средства для лечения однокопытных животных при паразитозах |
EP3720844A4 (en) | 2017-12-08 | 2021-08-11 | Adamis Pharmaceuticals Corporation | MEDICINAL COMPOSITIONS |
EP3749096A1 (en) | 2018-02-08 | 2020-12-16 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof |
PE20211275A1 (es) | 2018-07-09 | 2021-07-19 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos antihelminticos |
CN113260419A (zh) | 2018-11-20 | 2021-08-13 | 勃林格殷格翰动物保健美国公司 | 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法 |
MX2021011302A (es) | 2019-03-19 | 2022-01-19 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos. |
JP2023528822A (ja) | 2020-05-29 | 2023-07-06 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性複素環式化合物 |
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US3502661A (en) * | 1967-02-14 | 1970-03-24 | Pfizer & Co C | Process for making 1,4,5,6-tetrahydro-2-((2-substituted)vinyl) pyrimidines and 2-((2-substituted)vinyl)-2-imidazolines |
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US4032655A (en) * | 1974-05-15 | 1977-06-28 | Bayer Aktiengesellschaft | Phenylguanidines useful as anthelmintic agents |
IN142490B (es) * | 1974-05-15 | 1977-07-16 | Bayer Ag | |
SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
US5089490A (en) * | 1977-04-02 | 1992-02-18 | Hoechst Aktiengesellschaft | Cephem derivatives |
IL54474A (en) * | 1977-04-12 | 1982-04-30 | Ciba Geigy Ag | Benzimidazole derivatives,their preparation and anthelmintic compositions containing them |
NZ188459A (en) | 1977-10-03 | 1982-09-07 | Merck & Co Inc | Derivatives of c-076 compounds and pesticidal compositions |
US4199569A (en) * | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
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JPS57139012A (en) * | 1981-02-23 | 1982-08-27 | Sankyo Co Ltd | Anthelmintic composition |
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US4633372A (en) | 1985-08-26 | 1986-12-30 | The Standard Oil Company | Polyoxometalate-modified carbon electrodes and uses therefor in capacitors |
EP0237482A1 (de) * | 1986-03-06 | 1987-09-16 | Ciba-Geigy Ag | C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen |
DE3767560D1 (de) * | 1986-03-25 | 1991-02-28 | Sankyo Co | Makrolide verbindungen, ihre herstellung und verwendung. |
ATE75745T1 (de) * | 1986-07-02 | 1992-05-15 | Ciba Geigy Ag | Pestizide. |
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US4874749A (en) * | 1987-07-31 | 1989-10-17 | Merck & Co., Inc. | 4"-Deoxy-4-N-methylamino avermectin Bla/Blb |
DE3888936T2 (de) * | 1987-11-03 | 1994-07-21 | Beecham Group Plc | Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. |
NZ232422A (en) * | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
JP2893901B2 (ja) | 1990-09-07 | 1999-05-24 | 株式会社岐阜免疫研究所 | 動物用抗体含有油性ペースト製剤 |
JP3182229B2 (ja) | 1992-09-17 | 2001-07-03 | 大日本製薬株式会社 | 動物用懸濁型ペースト剤 |
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AUPM969994A0 (en) * | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
DE19520275A1 (de) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Endoparasitizide Mittel |
AU707949C (en) * | 1996-07-30 | 2006-01-19 | Merial, Inc. | Anthelmintic formulations |
IL126741A0 (en) | 1998-10-25 | 1999-08-17 | Yam Daniel | Solidification of fluid oils and their use |
NZ336832A (en) | 1999-07-21 | 2000-10-27 | Ancare New Zealand Ltd | Anthelmintic formulation comprising praziquantel, a macrolide, a preservative, buffer salts, defoaming agent, dispersing agent and water |
US6340672B1 (en) * | 2000-02-16 | 2002-01-22 | Phoenix Scientific, Inc. | Parasiticidal formulation and a method of making this formulation |
US6787342B2 (en) | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
US6207179B1 (en) * | 2000-05-18 | 2001-03-27 | Phoenix Scientific, Inc. | Parasiticidal formulation for animals and a method of making this formulation |
US7001889B2 (en) | 2002-06-21 | 2006-02-21 | Merial Limited | Anthelmintic oral homogeneous veterinary pastes |
-
2002
- 2002-06-21 US US10/177,822 patent/US7001889B2/en not_active Expired - Lifetime
-
2003
- 2003-06-13 ES ES03737140T patent/ES2306879T3/es not_active Expired - Lifetime
- 2003-06-13 MX MXPA05000172A patent/MXPA05000172A/es active IP Right Grant
- 2003-06-13 WO PCT/US2003/019025 patent/WO2004000034A2/en active Application Filing
- 2003-06-13 BR BR0312141-0A patent/BR0312141A/pt not_active Application Discontinuation
- 2003-06-13 NZ NZ537407A patent/NZ537407A/en not_active IP Right Cessation
- 2003-06-13 EP EP03737140A patent/EP1534072B1/en not_active Expired - Lifetime
- 2003-06-13 AT AT03737140T patent/ATE390123T1/de active
- 2003-06-13 DK DK03737140T patent/DK1534072T3/da active
- 2003-06-13 NZ NZ555185A patent/NZ555185A/en not_active IP Right Cessation
- 2003-06-13 JP JP2004515836A patent/JP4342440B2/ja not_active Expired - Lifetime
- 2003-06-13 DE DE60319996T patent/DE60319996T2/de not_active Expired - Lifetime
- 2003-06-13 CA CA2490309A patent/CA2490309C/en not_active Expired - Lifetime
- 2003-06-13 SI SI200331229T patent/SI1534072T1/sl unknown
- 2003-06-13 PT PT03737140T patent/PT1534072E/pt unknown
- 2003-06-20 AR ARP030102207A patent/AR039722A1/es not_active Application Discontinuation
-
2004
- 2004-12-20 ZA ZA2004/10250A patent/ZA200410250B/en unknown
- 2004-12-21 TN TNP2004000258A patent/TNSN04258A1/en unknown
- 2004-12-30 MA MA28026A patent/MA27313A1/fr unknown
-
2005
- 2005-04-15 US US11/107,048 patent/US7563773B2/en not_active Expired - Lifetime
-
2008
- 2008-06-24 CY CY20081100661T patent/CY1108533T1/el unknown
-
2009
- 2009-01-30 AU AU2009200336A patent/AU2009200336B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ZA200410250B (en) | 2005-11-30 |
JP2005533806A (ja) | 2005-11-10 |
NZ537407A (en) | 2007-07-27 |
US7001889B2 (en) | 2006-02-21 |
MA27313A1 (fr) | 2005-05-02 |
TNSN04258A1 (en) | 2007-03-12 |
AU2003238245A1 (en) | 2004-01-06 |
WO2004000034A3 (en) | 2004-02-26 |
BR0312141A (pt) | 2005-06-28 |
DE60319996T2 (de) | 2009-05-20 |
CA2490309A1 (en) | 2003-12-31 |
US20050176657A1 (en) | 2005-08-11 |
DE60319996D1 (de) | 2008-05-08 |
MXPA05000172A (es) | 2005-06-03 |
EP1534072A4 (en) | 2005-10-26 |
ES2306879T3 (es) | 2008-11-16 |
EP1534072B1 (en) | 2008-03-26 |
NZ555185A (en) | 2009-04-30 |
JP4342440B2 (ja) | 2009-10-14 |
AU2009200336B2 (en) | 2011-09-15 |
CY1108533T1 (el) | 2014-04-09 |
AU2009200336A1 (en) | 2009-02-19 |
SI1534072T1 (sl) | 2008-10-31 |
EP1534072A2 (en) | 2005-06-01 |
AR039722A1 (es) | 2005-03-09 |
US7563773B2 (en) | 2009-07-21 |
WO2004000034A2 (en) | 2003-12-31 |
ATE390123T1 (de) | 2008-04-15 |
PT1534072E (pt) | 2008-06-03 |
DK1534072T3 (da) | 2008-07-14 |
US20030236203A1 (en) | 2003-12-25 |
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