CA2352184C - Test de depistage permettant un depistage precoce du cancer colorectal - Google Patents

Test de depistage permettant un depistage precoce du cancer colorectal Download PDF

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Publication number
CA2352184C
CA2352184C CA002352184A CA2352184A CA2352184C CA 2352184 C CA2352184 C CA 2352184C CA 002352184 A CA002352184 A CA 002352184A CA 2352184 A CA2352184 A CA 2352184A CA 2352184 C CA2352184 C CA 2352184C
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Canada
Prior art keywords
mucus
cancer
rectum
marker
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002352184A
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English (en)
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CA2352184A1 (fr
Inventor
Jiri J. Krepinsky
Jacek Chociej (Deceased)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procyon Biopharma Inc
Original Assignee
Procyon Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002253093A external-priority patent/CA2253093A1/fr
Application filed by Procyon Biopharma Inc filed Critical Procyon Biopharma Inc
Priority to CA002352184A priority Critical patent/CA2352184C/fr
Priority claimed from PCT/CA1999/001034 external-priority patent/WO2000028329A1/fr
Publication of CA2352184A1 publication Critical patent/CA2352184A1/fr
Application granted granted Critical
Publication of CA2352184C publication Critical patent/CA2352184C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention se rapporte à un procédé permettant de déceler une néoplasie ou de dépister le cancer du colon ou du rectum. Ce procédé consiste à prélever un échantillon de mucus colorectal du rectum d'un patient, et à déceler la présence d'un marqueur sélectionné dans le groupe constitué d'aldéhydes aliphatiques à longue chaîne contenant 12 à 20 atomes de carbone, notamment CH3(CH2)14CHO et CH3(CH2)16CHO; et de précurseurs, liés au plasmalogène, de ce marqueur. De préférence, le procédé consiste à traiter le prélèvement avec un réactif de Schiff et à déceler la néoplasie ou à dépister le cancer du colon ou du rectum en fonction de la coloration produite dans le prélèvement par le traitement à environ 550-590 nm. Ce procédé ne requiert aucune addition d'enzyme permettant de détecter le marqueur disaccharide beta -D-Gal(1-3)-D-GalNAc( alpha 1-Thr/Ser) et un marqueur saccharide contenant du D-galactose et/ou du 2-acétamido-2-désoxy-D-galactose.
CA002352184A 1998-11-06 1999-11-03 Test de depistage permettant un depistage precoce du cancer colorectal Expired - Fee Related CA2352184C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002352184A CA2352184C (fr) 1998-11-06 1999-11-03 Test de depistage permettant un depistage precoce du cancer colorectal

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CA2,253,093 1998-11-06
CA002253093A CA2253093A1 (fr) 1998-11-06 1998-11-06 Test de depistage pour la detection precoce du cancer colorectal
US09/270,103 1999-03-16
US09/270,103 US6187591B1 (en) 1998-11-06 1999-03-16 Screening test for early detection of colorectal cancer
CA002352184A CA2352184C (fr) 1998-11-06 1999-11-03 Test de depistage permettant un depistage precoce du cancer colorectal
PCT/CA1999/001034 WO2000028329A1 (fr) 1998-11-06 1999-11-03 Test de depistage permettant un depistage precoce du cancer colorectal

Publications (2)

Publication Number Publication Date
CA2352184A1 CA2352184A1 (fr) 2000-05-18
CA2352184C true CA2352184C (fr) 2007-05-29

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA002352184A Expired - Fee Related CA2352184C (fr) 1998-11-06 1999-11-03 Test de depistage permettant un depistage precoce du cancer colorectal

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CA (1) CA2352184C (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113244246B (zh) * 2021-05-11 2022-05-06 江南大学 一种微生物源缩醛磷脂在治疗结肠癌中的应用

Also Published As

Publication number Publication date
CA2352184A1 (fr) 2000-05-18

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