CA2343713A1 - Utilisation de pex dans le traitement de maladies metaboliques des os - Google Patents

Utilisation de pex dans le traitement de maladies metaboliques des os Download PDF

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Publication number
CA2343713A1
CA2343713A1 CA002343713A CA2343713A CA2343713A1 CA 2343713 A1 CA2343713 A1 CA 2343713A1 CA 002343713 A CA002343713 A CA 002343713A CA 2343713 A CA2343713 A CA 2343713A CA 2343713 A1 CA2343713 A1 CA 2343713A1
Authority
CA
Canada
Prior art keywords
bone diseases
metabolic bone
pex
treatment
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002343713A
Other languages
English (en)
Other versions
CA2343713C (fr
Inventor
Andrew C. Karaplis
David Goltzman
Mark L. Lipman
Janet E. Henderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002245903A external-priority patent/CA2245903A1/fr
Application filed by Individual filed Critical Individual
Priority to CA002343713A priority Critical patent/CA2343713C/fr
Publication of CA2343713A1 publication Critical patent/CA2343713A1/fr
Application granted granted Critical
Publication of CA2343713C publication Critical patent/CA2343713C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002343713A 1998-09-28 1999-09-27 Utilisation de pex dans le traitement de maladies metaboliques des os Expired - Fee Related CA2343713C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002343713A CA2343713C (fr) 1998-09-28 1999-09-27 Utilisation de pex dans le traitement de maladies metaboliques des os

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA002245903A CA2245903A1 (fr) 1998-09-28 1998-09-28 Utilisation de pex dans le traitement des maladies osseuses metaboliques
CA2,245,903 1998-09-28
PCT/CA1999/000895 WO2000018954A2 (fr) 1998-09-28 1999-09-27 Utilisation de pex dans le traitement de maladies metaboliques des os
CA002343713A CA2343713C (fr) 1998-09-28 1999-09-27 Utilisation de pex dans le traitement de maladies metaboliques des os

Publications (2)

Publication Number Publication Date
CA2343713A1 true CA2343713A1 (fr) 2000-04-06
CA2343713C CA2343713C (fr) 2008-01-08

Family

ID=25680440

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002343713A Expired - Fee Related CA2343713C (fr) 1998-09-28 1999-09-27 Utilisation de pex dans le traitement de maladies metaboliques des os

Country Status (1)

Country Link
CA (1) CA2343713C (fr)

Also Published As

Publication number Publication date
CA2343713C (fr) 2008-01-08

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MKLA Lapsed

Effective date: 20150928