CA2294053A1 - Methods for the detection of multiple single nucleotide polymorphisms in a single reaction - Google Patents

Methods for the detection of multiple single nucleotide polymorphisms in a single reaction Download PDF

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Publication number
CA2294053A1
CA2294053A1 CA002294053A CA2294053A CA2294053A1 CA 2294053 A1 CA2294053 A1 CA 2294053A1 CA 002294053 A CA002294053 A CA 002294053A CA 2294053 A CA2294053 A CA 2294053A CA 2294053 A1 CA2294053 A1 CA 2294053A1
Authority
CA
Canada
Prior art keywords
nucleotide
group
molecule
primer
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002294053A
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English (en)
French (fr)
Inventor
Tina Mcintosh
Steven Head
Philip Goelet
Michael T. Boyce-Jacino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Cellmark Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2294053A1 publication Critical patent/CA2294053A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002294053A 1997-06-25 1998-06-24 Methods for the detection of multiple single nucleotide polymorphisms in a single reaction Abandoned CA2294053A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88184597A 1997-06-25 1997-06-25
US08/881,845 1997-06-25
PCT/US1998/013042 WO1998059066A1 (en) 1997-06-25 1998-06-24 Methods for the detection of multiple single nucleotide polymorphisms in a single reaction

Publications (1)

Publication Number Publication Date
CA2294053A1 true CA2294053A1 (en) 1998-12-30

Family

ID=25379330

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002294053A Abandoned CA2294053A1 (en) 1997-06-25 1998-06-24 Methods for the detection of multiple single nucleotide polymorphisms in a single reaction

Country Status (5)

Country Link
EP (1) EP0994960A1 (de)
JP (1) JP2002508664A (de)
AU (1) AU8162498A (de)
CA (1) CA2294053A1 (de)
WO (1) WO1998059066A1 (de)

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US6403309B1 (en) 1999-03-19 2002-06-11 Valigen (Us), Inc. Methods for detection of nucleic acid polymorphisms using peptide-labeled oligonucleotides and antibody arrays
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US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
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US6762018B1 (en) 1999-12-23 2004-07-13 Tetragen Sa Analysis of nucleotide polymorphisms at a site
US6355433B1 (en) 2000-06-02 2002-03-12 Dna Sciences, Inc. Determination of nucleotide sequence variations through limited primer extension
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
AU2002216035A1 (en) * 2000-11-13 2002-05-21 Gnothis Holding Sa Detection of nucleic acid polymorphisms
WO2002048402A2 (en) 2000-12-13 2002-06-20 Nugen Technologies, Inc. Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
US20020142336A1 (en) * 2001-02-02 2002-10-03 Genome Therapeutics Corporation Methods for determining a nucleotide at a specific location within a nucleic acid molecule
AU2002252279B2 (en) 2001-03-09 2005-05-12 Nugen Technologies, Inc. Methods and compositions for amplification of RNA sequences
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AU2003224141A1 (en) * 2002-04-30 2003-11-17 Gnothis Holding Sa Multiplexed determination of nucleic acid polymorphisms
DE10245145B4 (de) * 2002-09-27 2004-12-02 IPK-Institut für Pflanzengenetik und Kulturpflanzenforschung Verfahren zum Nachweis von SNPs auf polydimensionalen Microarrays
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EP1613778B1 (de) 2003-04-14 2014-11-26 Nugen Technologies, Inc. Globale amplifizierung unter verwendung von zufallsgeprimeten zusammen gesetzten primern
US20040259100A1 (en) 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
TW200525026A (en) 2003-12-25 2005-08-01 Riken Method of amplifying nucleic acid and method of detecting mutated nucleic acid using the same
EP1713936B1 (de) * 2004-02-12 2009-12-09 Population Genetics Technologies Ltd Corporation of Great Britain Genetische analyse mittels sequenzspezifischem sortieren
US7702466B1 (en) 2004-06-29 2010-04-20 Illumina, Inc. Systems and methods for selection of nucleic acid sequence probes
US7393665B2 (en) 2005-02-10 2008-07-01 Population Genetics Technologies Ltd Methods and compositions for tagging and identifying polynucleotides
EP1888779A4 (de) 2005-05-20 2009-06-10 Synergenz Bioscience Ltd Verfahren zur analyse von polymorphismen sowie verwendungen davon
EP1929046B1 (de) 2005-09-07 2012-07-11 Nugen Technologies, Inc. Verbessertes nukleinsäureamplifikationsverfahren
US7329860B2 (en) 2005-11-23 2008-02-12 Illumina, Inc. Confocal imaging methods and apparatus
JP5220596B2 (ja) * 2006-05-24 2013-06-26 独立行政法人産業技術総合研究所 DNAポリメラーゼβを用いた核酸合成法及び1分子シーケンス法
CN101978073B (zh) 2008-01-25 2014-12-10 诊疗实验室 用于评估药物反应的方法和组合物
US20090203531A1 (en) 2008-02-12 2009-08-13 Nurith Kurn Method for Archiving and Clonal Expansion
WO2009117698A2 (en) 2008-03-21 2009-09-24 Nugen Technologies, Inc. Methods of rna amplification in the presence of dna
ES2596655T3 (es) 2010-02-01 2017-01-11 Illumina Inc. Procedimientos de enfoque y sistemas y conjuntos ópticos que usan los mismos
DE202011003570U1 (de) 2010-03-06 2012-01-30 Illumina, Inc. Systeme und Vorrichtungen zum Detektieren optischer Signale aus einer Probe
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
WO2012155084A1 (en) * 2011-05-12 2012-11-15 Netbio, Inc. Methods and compositions for rapid multiplex amplification of str loci
PT3623481T (pt) 2011-09-23 2021-10-15 Illumina Inc Composições para sequenciação de ácidos nucleicos
US10378051B2 (en) 2011-09-29 2019-08-13 Illumina Cambridge Limited Continuous extension and deblocking in reactions for nucleic acids synthesis and sequencing
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CN108463287B (zh) 2016-03-28 2021-01-15 亿明达股份有限公司 多平面微阵列
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EP3596099B1 (de) 2017-03-06 2024-07-24 Singular Genomics Systems, Inc. Verfahren zur nukleinsäuresequenzierung durch synthese (sbs), die sbs-zyklusschritte kombinieren
JP6994513B2 (ja) 2017-03-24 2022-03-04 ジェン-プローブ・インコーポレーテッド 試料中のウイルス病原体を検出するための組成物および方法
CA3067144C (en) 2018-03-09 2023-09-05 Illumina Cambridge Limited Generalized stochastic super-resolution sequencing
US11421271B2 (en) 2019-03-28 2022-08-23 Illumina Cambridge Limited Methods and compositions for nucleic acid sequencing using photoswitchable labels
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US20230215515A1 (en) 2021-12-23 2023-07-06 Illumina Software, Inc. Facilitating secure execution of external workflows for genomic sequencing diagnostics
CA3242624A1 (en) 2021-12-29 2023-07-06 Shannon Whitmore Automatically switching variant analysis model versions for genomic analysis applications
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US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
US5610287A (en) * 1993-12-06 1997-03-11 Molecular Tool, Inc. Method for immobilizing nucleic acid molecules

Also Published As

Publication number Publication date
JP2002508664A (ja) 2002-03-19
AU8162498A (en) 1999-01-04
EP0994960A1 (de) 2000-04-26
WO1998059066A1 (en) 1998-12-30

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Legal Events

Date Code Title Description
FZDE Discontinued