CA2265239A1 - Genetically engineered l-sorbose reductase-deficient mutants - Google Patents

Genetically engineered l-sorbose reductase-deficient mutants Download PDF

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Publication number
CA2265239A1
CA2265239A1 CA002265239A CA2265239A CA2265239A1 CA 2265239 A1 CA2265239 A1 CA 2265239A1 CA 002265239 A CA002265239 A CA 002265239A CA 2265239 A CA2265239 A CA 2265239A CA 2265239 A1 CA2265239 A1 CA 2265239A1
Authority
CA
Canada
Prior art keywords
sorbose
gene
genetically engineered
reductase
engineered microorganism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002265239A
Other languages
English (en)
French (fr)
Inventor
Tatsuo Hoshino
Takahide Kon
Masako Shinjoh
Masaaki Tazoe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2265239A1 publication Critical patent/CA2265239A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002265239A 1998-03-13 1999-03-12 Genetically engineered l-sorbose reductase-deficient mutants Abandoned CA2265239A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98104546 1998-03-13
EP98104546.1 1998-03-13

Publications (1)

Publication Number Publication Date
CA2265239A1 true CA2265239A1 (en) 1999-09-13

Family

ID=8231579

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002265239A Abandoned CA2265239A1 (en) 1998-03-13 1999-03-12 Genetically engineered l-sorbose reductase-deficient mutants

Country Status (10)

Country Link
US (1) US6664082B1 (https=)
JP (1) JP2000060576A (https=)
KR (1) KR100710948B1 (https=)
CN (1) CN1163593C (https=)
AU (1) AU2039099A (https=)
BR (1) BR9902010A (https=)
CA (1) CA2265239A1 (https=)
DE (1) DE69937086T2 (https=)
ID (1) ID23461A (https=)
NO (1) NO991197L (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1846555A1 (en) * 2005-02-11 2007-10-24 DSMIP Assets B.V. Alcohol dehydrogenase gene from gluconobacter oxydans
BRPI0606935A2 (pt) * 2005-02-11 2009-07-28 Dsm Ip Assets Bv novo gene sms 04
WO2007028610A2 (en) * 2005-09-09 2007-03-15 Dsm Ip Assets B.V. Novel gene gms 08
WO2012104987A1 (ja) * 2011-02-01 2012-08-09 国立大学法人福島大学 酵素及びその製造方法
CN114507681B (zh) * 2022-03-17 2023-08-22 乐山利源科技有限公司 一种山梨糖还原酶OpCR基因、突变体及编码蛋白和在制备玻色因中的应用
EP4488376A1 (de) 2023-07-07 2025-01-08 Annikki GmbH Verfahren zur herstellung einer wässerigen lösung enthaltend l-sorbose

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3537624A1 (de) * 1985-10-23 1987-04-23 Bayer Ag Feinteilige isometrische hexaferritpigmente, verfahren zu ihrer herstellung und deren verwendung
DE3781699T2 (de) 1986-02-11 1993-03-11 Takeda Chemical Industries Ltd Verfahren zur herstellung von l-sorbose.
ATE360685T1 (de) 1995-02-27 2007-05-15 Dsm Ip Assets Bv D-sorbitol-dehydrogenase

Also Published As

Publication number Publication date
US6664082B1 (en) 2003-12-16
ID23461A (id) 2000-04-27
BR9902010A (pt) 2000-05-02
JP2000060576A (ja) 2000-02-29
CN1229134A (zh) 1999-09-22
KR100710948B1 (ko) 2007-04-24
NO991197L (no) 1999-09-14
DE69937086D1 (de) 2007-10-25
NO991197D0 (no) 1999-03-11
AU2039099A (en) 1999-09-23
DE69937086T2 (de) 2008-06-12
CN1163593C (zh) 2004-08-25
KR19990077840A (ko) 1999-10-25
HK1021993A1 (en) 2000-07-21

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Legal Events

Date Code Title Description
FZDE Discontinued