CA2221556A1 - Buffer composition for reagents for immunoassay - Google Patents

Buffer composition for reagents for immunoassay

Info

Publication number
CA2221556A1
CA2221556A1 CA002221556A CA2221556A CA2221556A1 CA 2221556 A1 CA2221556 A1 CA 2221556A1 CA 002221556 A CA002221556 A CA 002221556A CA 2221556 A CA2221556 A CA 2221556A CA 2221556 A1 CA2221556 A1 CA 2221556A1
Authority
CA
Canada
Prior art keywords
composition
immunoassay
reagents
buffer
buffer composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002221556A
Other languages
French (fr)
Other versions
CA2221556C (en
Inventor
Steve D. Figard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/482,710 external-priority patent/US5616460A/en
Application filed by Individual filed Critical Individual
Publication of CA2221556A1 publication Critical patent/CA2221556A1/en
Application granted granted Critical
Publication of CA2221556C publication Critical patent/CA2221556C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

An aqueous composition suitable for use when performing immunological procedures. The composition includes at least one biological buffer, dithiothreitol (alternatively referred to herein as "DTT"), and ethylene glycol. The composition can also include at least one biological detergent, at least one source of positive and negative counterions, e.g., salt, and at least one viscosity modifier, e.g., sugar. The buffer also can include at least one preservative, such as sodium azide. The pH of the composition preferably ranges from about 6.4 to 7.2. A kit containing the composition is also disclosed.
CA002221556A 1995-06-07 1996-05-24 Buffer composition for reagents for immunoassay Expired - Fee Related CA2221556C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/482,710 US5616460A (en) 1995-06-07 1995-06-07 Buffer composition for reagents for immunoassay
US08/482,710 1995-06-07
PCT/US1996/007745 WO1996041164A1 (en) 1995-06-07 1996-05-24 Buffer composition for reagents for immunoassay

Publications (2)

Publication Number Publication Date
CA2221556A1 true CA2221556A1 (en) 1996-12-19
CA2221556C CA2221556C (en) 2007-08-14

Family

ID=38434455

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002221556A Expired - Fee Related CA2221556C (en) 1995-06-07 1996-05-24 Buffer composition for reagents for immunoassay

Country Status (1)

Country Link
CA (1) CA2221556C (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112500514A (en) * 2020-11-11 2021-03-16 四川迈克生物新材料技术有限公司 Polystyrene latex microsphere and preparation method thereof
CN114252595A (en) * 2021-12-23 2022-03-29 武汉生之源生物科技股份有限公司 Magnetic bead diluent and immunoassay kit for reducing sample matrix interference

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112500514A (en) * 2020-11-11 2021-03-16 四川迈克生物新材料技术有限公司 Polystyrene latex microsphere and preparation method thereof
CN114252595A (en) * 2021-12-23 2022-03-29 武汉生之源生物科技股份有限公司 Magnetic bead diluent and immunoassay kit for reducing sample matrix interference
CN114252595B (en) * 2021-12-23 2024-08-16 武汉生之源生物科技股份有限公司 Magnetic bead diluent for reducing sample matrix interference and immunodetection kit

Also Published As

Publication number Publication date
CA2221556C (en) 2007-08-14

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Legal Events

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