CA2198348A1 - Methode analgesique avec analogues de dynorphine, tronques au n terminal - Google Patents
Methode analgesique avec analogues de dynorphine, tronques au n terminalInfo
- Publication number
- CA2198348A1 CA2198348A1 CA002198348A CA2198348A CA2198348A1 CA 2198348 A1 CA2198348 A1 CA 2198348A1 CA 002198348 A CA002198348 A CA 002198348A CA 2198348 A CA2198348 A CA 2198348A CA 2198348 A1 CA2198348 A1 CA 2198348A1
- Authority
- CA
- Canada
- Prior art keywords
- arg
- leu
- lys
- dynorphin
- gly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002198348A CA2198348A1 (fr) | 1994-08-26 | 1994-08-26 | Methode analgesique avec analogues de dynorphine, tronques au n terminal |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002198348A CA2198348A1 (fr) | 1994-08-26 | 1994-08-26 | Methode analgesique avec analogues de dynorphine, tronques au n terminal |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2198348A1 true CA2198348A1 (fr) | 1996-03-07 |
Family
ID=4160024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002198348A Abandoned CA2198348A1 (fr) | 1994-08-26 | 1994-08-26 | Methode analgesique avec analogues de dynorphine, tronques au n terminal |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2198348A1 (fr) |
-
1994
- 1994-08-26 CA CA002198348A patent/CA2198348A1/fr not_active Abandoned
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2137916A1 (fr) | Analogues de peptides dynorphine des-tyr | |
EP0788371A1 (fr) | Procede analgesique utilisant des analogues de dynorphine tronques au niveau de la terminaison n | |
CA2224795C (fr) | Compositions et formulations permettant de produire une analgesie et d'inhiber la progression de troubles lies a des douleurs neuropathiques | |
Deakin et al. | Influence of N-terminal acetylation and C-terminal proteolysis on the analgesic activity of β-endorphin | |
US5512544A (en) | Pharmaceutical compositions comprising an anticytokine | |
CN106432422B (zh) | 一组具有镇痛作用的肽及其药物组合物和应用 | |
Kosterlitz et al. | Peptides with morphine-like action in the brain | |
EP0415693A1 (fr) | Composition et procédé pour la potentialisation sélective de l'effet des opiates et réduction de la tolérance et dépendance des opiates | |
Bueno et al. | Central and peripheral control of gastrointestinal and colonic motility by endogenous opiates in conscious dogs | |
EP4008337A1 (fr) | Effet synergique d'un polypeptide de la neurotoxine du cobra sur l'inhibition de l'hyperalgie et de la tolérance induites par les opioïdes et sur le soulagement de la douleur associée à celles-ci | |
Millan et al. | Activation of periaqueductal grey pools of β-endorphin by analgetic electrical stimulation in freely moving rats | |
Koob et al. | Neurochemical substrates for opiate reinforcement | |
Hooke et al. | [Des-Tyr1] dynorphin A-(2-17) has naloxone-insensitive antinociceptive effect in the writhing assay. | |
CA2198348A1 (fr) | Methode analgesique avec analogues de dynorphine, tronques au n terminal | |
US5807827A (en) | Des-Tyr dynorphin analogues | |
WO2017014604A1 (fr) | Nouveau peptide et utilisation associée | |
EP2195006B1 (fr) | Utilisation d'un analogue de la biphaline comme agent pharmaceutique analgésique | |
EP0016136A1 (fr) | Inhibition par des peptides de la tolerance et de la dependance physiques a la morphine | |
Tortella | Opioid peptides: possible physiological role as endogenous anticonvulsants | |
EP3765056B1 (fr) | Compositions, méthodes et utilisations d'un peptide-1 associé à l'extrémité c-terminale de la téneurine (tcap-1) pour traiter la dépendance aux opioïdes | |
Karaus et al. | Effects of CCK‐receptor antagonist on colonic motor activity in dogs | |
WO1993006841A1 (fr) | Analogue peptidique | |
US20220119447A1 (en) | Peptide and for treating inflammatory disease and pain using the same | |
Lipkowski et al. | Biphalin: a multireceptor opioid ligand | |
Jonsdottir et al. | Somatic nerve stimulation and cholera-induced net fluid secretion in the small intestine of the rat: evidence for an opioid effect |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |