CA2124003A1 - Phenol derivatives as agonists of a cyclic amp dependent protein kinase - Google Patents

Phenol derivatives as agonists of a cyclic amp dependent protein kinase

Info

Publication number
CA2124003A1
CA2124003A1 CA002124003A CA2124003A CA2124003A1 CA 2124003 A1 CA2124003 A1 CA 2124003A1 CA 002124003 A CA002124003 A CA 002124003A CA 2124003 A CA2124003 A CA 2124003A CA 2124003 A1 CA2124003 A1 CA 2124003A1
Authority
CA
Canada
Prior art keywords
compound
formula
group
hereinbefore defined
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002124003A
Other languages
English (en)
French (fr)
Inventor
Roderick Alan Porter
Hunter Douglas Prain
Kenneth John Murray
Brian Herbert Warrington
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2124003A1 publication Critical patent/CA2124003A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4021—Esters of aromatic acids (P-C aromatic linkage)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002124003A 1991-11-20 1992-11-16 Phenol derivatives as agonists of a cyclic amp dependent protein kinase Abandoned CA2124003A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919124579A GB9124579D0 (en) 1991-11-20 1991-11-20 Chemical compounds
GB9124579.5 1991-11-20

Publications (1)

Publication Number Publication Date
CA2124003A1 true CA2124003A1 (en) 1993-05-27

Family

ID=10704882

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002124003A Abandoned CA2124003A1 (en) 1991-11-20 1992-11-16 Phenol derivatives as agonists of a cyclic amp dependent protein kinase

Country Status (11)

Country Link
EP (1) EP0620815A1 (enrdf_load_stackoverflow)
JP (1) JPH07503235A (enrdf_load_stackoverflow)
AU (1) AU2927492A (enrdf_load_stackoverflow)
CA (1) CA2124003A1 (enrdf_load_stackoverflow)
GB (1) GB9124579D0 (enrdf_load_stackoverflow)
MX (1) MX9206709A (enrdf_load_stackoverflow)
NZ (1) NZ245168A (enrdf_load_stackoverflow)
PT (1) PT101073A (enrdf_load_stackoverflow)
TW (1) TW221812B (enrdf_load_stackoverflow)
WO (1) WO1993010107A1 (enrdf_load_stackoverflow)
ZA (1) ZA928894B (enrdf_load_stackoverflow)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3590082A (en) * 1967-10-06 1971-06-29 Merck & Co Inc 4-(p-fluorophenyl)salicylamide derivatives
NZ238202A (en) * 1990-05-21 1994-01-26 Smith Kline French Lab Pyridine and benzene derivatives and medicaments.

Also Published As

Publication number Publication date
PT101073A (pt) 1994-02-28
ZA928894B (en) 1994-05-18
JPH07503235A (ja) 1995-04-06
TW221812B (enrdf_load_stackoverflow) 1994-03-21
EP0620815A1 (en) 1994-10-26
MX9206709A (es) 1993-05-01
GB9124579D0 (en) 1992-01-08
NZ245168A (en) 1995-06-27
WO1993010107A1 (en) 1993-05-27
AU2927492A (en) 1993-06-15

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Legal Events

Date Code Title Description
FZDE Dead