CA2086874C - Methods for administration of taxol - Google Patents

Methods for administration of taxol

Info

Publication number
CA2086874C
CA2086874C CA2086874A CA2086874A CA2086874C CA 2086874 C CA2086874 C CA 2086874C CA 2086874 A CA2086874 A CA 2086874A CA 2086874 A CA2086874 A CA 2086874A CA 2086874 C CA2086874 C CA 2086874C
Authority
CA
Canada
Prior art keywords
taxol
cancer therapy
products
administration
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2086874A
Other languages
French (fr)
Other versions
CA2086874A1 (en
CA2086874E (en
Inventor
Renzo Mauro Canetta
Elizabeth Eisenhauer
Marcel Rozencweig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25448992&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2086874(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CA2086874A1 publication Critical patent/CA2086874A1/en
Publication of CA2086874C publication Critical patent/CA2086874C/en
Application granted granted Critical
Publication of CA2086874E publication Critical patent/CA2086874E/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention concerns products containing taxol for use in cancer therapy.According to this invention, the products contain an anti-neoplastically effective amount of taxol and sufficient medications to prevent severe anaphylactic-like reactions and are formulated and packaged for separate or sequential or simultaneous use in cancer therapy with a patient over a period of about 24 hours or less.These products find application in the treatment of all types of cancers, treatable by taxol.
CA002086874A 1992-08-03 1993-01-07 Methods for administration of taxol Expired - Fee Related CA2086874E (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92362892A 1992-08-03 1992-08-03
US07/923,628 1992-08-03

Publications (3)

Publication Number Publication Date
CA2086874A1 CA2086874A1 (en) 1994-02-04
CA2086874C true CA2086874C (en) 1998-09-01
CA2086874E CA2086874E (en) 2000-01-04

Family

ID=25448992

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002086874A Expired - Fee Related CA2086874E (en) 1992-08-03 1993-01-07 Methods for administration of taxol

Country Status (23)

Country Link
US (5) US5641803A (en)
EP (3) EP0584001B1 (en)
JP (1) JP2848760B2 (en)
AT (1) ATE152910T1 (en)
AU (3) AU641894B3 (en)
BE (1) BE1006497A5 (en)
CA (1) CA2086874E (en)
CH (1) CH686868A5 (en)
DE (2) DE69310634T2 (en)
DK (2) DK65293A (en)
ES (2) ES2105926B1 (en)
FR (1) FR2694192B1 (en)
GB (1) GB9311740D0 (en)
GR (2) GR1001617B (en)
IE (1) IE80620B1 (en)
IL (1) IL105879A (en)
IT (1) IT1276041B1 (en)
MY (1) MY109862A (en)
NL (1) NL9301086A (en)
NZ (1) NZ245795A (en)
PT (1) PT101289A (en)
SE (1) SE513082C2 (en)
ZA (1) ZA93686B (en)

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FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2629818B1 (en) * 1988-04-06 1990-11-16 Centre Nat Rech Scient PROCESS FOR THE PREPARATION OF TAXOL
AU2005692A (en) * 1991-05-08 1992-12-21 United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method for designing cancer treatment regimens and methods and pharmaceutical compositions for the treatment of cancer
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Also Published As

Publication number Publication date
ITMI931714A0 (en) 1993-07-29
CA2086874A1 (en) 1994-02-04
GB9311740D0 (en) 1993-07-21
MY109862A (en) 1997-09-30
EP0584001B1 (en) 1997-05-14
AU3216893A (en) 1994-02-10
DK65293D0 (en) 1993-06-04
ZA93686B (en) 1993-09-06
IE930433A1 (en) 1994-02-09
ITMI931714A1 (en) 1995-01-29
AU641894B3 (en) 1993-09-30
AU4207096A (en) 1996-04-26
EP0584001A1 (en) 1994-02-23
IE80620B1 (en) 1998-10-21
US5670537A (en) 1997-09-23
AU704393B2 (en) 1999-04-22
SE9301951D0 (en) 1993-06-08
US5641803A (en) 1997-06-24
EP0783885A3 (en) 1997-08-06
DE69310634T2 (en) 1998-01-02
NZ245795A (en) 1999-05-28
ES2105926B1 (en) 1998-07-01
PT101289A (en) 1994-04-29
AU704393C (en) 2002-07-25
FR2694192A1 (en) 1994-02-04
IT1276041B1 (en) 1997-10-24
EP0783885A2 (en) 1997-07-16
DK0584001T3 (en) 1997-08-25
JP2848760B2 (en) 1999-01-20
EP0783886A3 (en) 1997-07-23
IL105879A (en) 1998-08-16
GR1001617B (en) 1994-07-29
JPH07233064A (en) 1995-09-05
NL9301086A (en) 1994-03-01
US5665761A (en) 1997-09-09
US5621001A (en) 1997-04-15
IL105879A0 (en) 1993-10-20
CH686868A5 (en) 1996-07-31
DK65293A (en) 1994-02-04
ES2101261T3 (en) 1997-07-01
CA2086874E (en) 2000-01-04
DE69310634D1 (en) 1997-06-19
BE1006497A5 (en) 1994-09-13
ATE152910T1 (en) 1997-05-15
GR3024415T3 (en) 1997-11-28
DE4325927A1 (en) 1994-03-10
EP0783886A2 (en) 1997-07-16
SE9301951L (en) 1994-02-07
SE513082C2 (en) 2000-07-03
DE4325927B4 (en) 2004-04-15
ES2105926A1 (en) 1997-10-16
US6414014B1 (en) 2002-07-02
FR2694192B1 (en) 1995-01-27

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