CA2065210A1 - Matrice a liberation controlee pour produits pharmaceutiques - Google Patents

Matrice a liberation controlee pour produits pharmaceutiques

Info

Publication number
CA2065210A1
CA2065210A1 CA2065210A CA2065210A CA2065210A1 CA 2065210 A1 CA2065210 A1 CA 2065210A1 CA 2065210 A CA2065210 A CA 2065210A CA 2065210 A CA2065210 A CA 2065210A CA 2065210 A1 CA2065210 A1 CA 2065210A1
Authority
CA
Canada
Prior art keywords
controlled release
pharmaceuticals
matrix
release matrix
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2065210A
Other languages
English (en)
Other versions
CA2065210C (fr
Inventor
Thinnayam N. Krishnamurthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Thinnayam N. Krishnamurthy
Euroceltique, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US758,883 priority Critical
Priority to US07/758,883 priority patent/US5215758A/en
Application filed by Thinnayam N. Krishnamurthy, Euroceltique, S.A. filed Critical Thinnayam N. Krishnamurthy
Publication of CA2065210A1 publication Critical patent/CA2065210A1/fr
Application granted granted Critical
Publication of CA2065210C publication Critical patent/CA2065210C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/15Suppositories
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/964Sustained or differential release type
    • Y10S514/965Discrete particles in supporting matrix
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/966Rectal
CA002065210A 1991-09-11 1992-04-06 Matrice a liberation controlee pour produits pharmaceutiques Expired - Lifetime CA2065210C (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US758,883 1991-09-11
US07/758,883 US5215758A (en) 1991-09-11 1991-09-11 Controlled release matrix suppository for pharmaceuticals

Publications (2)

Publication Number Publication Date
CA2065210A1 true CA2065210A1 (fr) 1993-03-12
CA2065210C CA2065210C (fr) 2000-08-29

Family

ID=25053475

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002065210A Expired - Lifetime CA2065210C (fr) 1991-09-11 1992-04-06 Matrice a liberation controlee pour produits pharmaceutiques

Country Status (13)

Country Link
US (2) US5215758A (fr)
EP (2) EP0698389B1 (fr)
JP (2) JP3034125B2 (fr)
KR (2) KR100203339B1 (fr)
AT (2) AT187887T (fr)
AU (1) AU653048B2 (fr)
CA (1) CA2065210C (fr)
DE (2) DE69230475T2 (fr)
DK (2) DK0531611T3 (fr)
ES (2) ES2139798T3 (fr)
GR (1) GR3022572T3 (fr)
IL (2) IL101758A (fr)
ZA (1) ZA923417B (fr)

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Also Published As

Publication number Publication date
ES2139798T3 (es) 2000-02-16
DK0531611T3 (da) 1997-05-26
EP0531611B1 (fr) 1996-12-04
US5508043A (en) 1996-04-16
JP3624123B2 (ja) 2005-03-02
KR100225493B1 (en) 1999-10-15
CA2065210C (fr) 2000-08-29
KR930005616A (ko) 1993-04-20
JP2000136149A (ja) 2000-05-16
IL101758D0 (en) 1992-12-30
EP0698389B1 (fr) 1999-12-22
IL117356A (en) 2000-08-31
IL101758A (en) 1996-12-05
ES2097826T3 (es) 1997-04-16
AT187887T (de) 2000-01-15
AT145820T (de) 1996-12-15
DE69215612T2 (de) 1997-05-15
JP3034125B2 (ja) 2000-04-17
DE69230475T2 (de) 2000-07-13
KR100203339B1 (ko) 1999-06-15
EP0698389A1 (fr) 1996-02-28
AU653048B2 (en) 1994-09-15
EP0531611A1 (fr) 1993-03-17
DK0698389T3 (da) 2000-05-01
DE69230475D1 (de) 2000-01-27
GR3022572T3 (en) 1997-05-31
IL117356D0 (en) 1996-07-23
US5215758A (en) 1993-06-01
AU2107392A (en) 1993-03-18
ZA923417B (en) 1993-01-27
JPH05148159A (ja) 1993-06-15
DE69215612D1 (de) 1997-01-16

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