CA2016765C - Sels cristallins stables de monohydrate de 2',3'-didesoxyinosine, de monohydrate de 2',3'-didesoxy-2',3'-didehydrothymidine, et de hemihydrate de 2',3'-didesoxy-2'-fluoroinosine, hautement solubles dans l'eau et antiviraux - Google Patents

Sels cristallins stables de monohydrate de 2',3'-didesoxyinosine, de monohydrate de 2',3'-didesoxy-2',3'-didehydrothymidine, et de hemihydrate de 2',3'-didesoxy-2'-fluoroinosine, hautement solubles dans l'eau et antiviraux

Info

Publication number
CA2016765C
CA2016765C CA002016765A CA2016765A CA2016765C CA 2016765 C CA2016765 C CA 2016765C CA 002016765 A CA002016765 A CA 002016765A CA 2016765 A CA2016765 A CA 2016765A CA 2016765 C CA2016765 C CA 2016765C
Authority
CA
Canada
Prior art keywords
salt
dideoxy
virus
salt according
stable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002016765A
Other languages
English (en)
Other versions
CA2016765A1 (fr
Inventor
Murray A. Kaplan
Robert K. Perrone
Joseph B. Bogardus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CA2016765A1 publication Critical patent/CA2016765A1/fr
Application granted granted Critical
Publication of CA2016765C publication Critical patent/CA2016765C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002016765A 1989-05-15 1990-05-14 Sels cristallins stables de monohydrate de 2',3'-didesoxyinosine, de monohydrate de 2',3'-didesoxy-2',3'-didehydrothymidine, et de hemihydrate de 2',3'-didesoxy-2'-fluoroinosine, hautement solubles dans l'eau et antiviraux Expired - Fee Related CA2016765C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35206589A 1989-05-15 1989-05-15
US352,065 1989-05-15

Publications (2)

Publication Number Publication Date
CA2016765A1 CA2016765A1 (fr) 1990-11-15
CA2016765C true CA2016765C (fr) 1997-10-21

Family

ID=23383649

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002016765A Expired - Fee Related CA2016765C (fr) 1989-05-15 1990-05-14 Sels cristallins stables de monohydrate de 2',3'-didesoxyinosine, de monohydrate de 2',3'-didesoxy-2',3'-didehydrothymidine, et de hemihydrate de 2',3'-didesoxy-2'-fluoroinosine, hautement solubles dans l'eau et antiviraux

Country Status (11)

Country Link
JP (1) JP2926257B2 (fr)
CA (1) CA2016765C (fr)
CZ (1) CZ9602347A3 (fr)
DD (1) DD298406A5 (fr)
MY (1) MY116824A (fr)
NZ (1) NZ233646A (fr)
PL (1) PL163999B1 (fr)
SK (2) SK237290A3 (fr)
TW (1) TW233301B (fr)
YU (1) YU92890A (fr)
ZA (1) ZA903662B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122207B2 (en) 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
JP4731121B2 (ja) * 2004-02-02 2011-07-20 協和発酵キリン株式会社 キサンチン誘導体水和物
JP5485138B2 (ja) * 2008-03-28 2014-05-07 浜理薬品工業株式会社 エチニルチミジン化合物の精製方法
JP5485140B2 (ja) * 2008-04-10 2014-05-07 浜理薬品工業株式会社 ５−メチルウリジンを出発原料とするエチニルチミジン化合物の製造方法

Also Published As

Publication number Publication date
JPH035477A (ja) 1991-01-11
SK127397A3 (en) 1998-08-05
SK279130B6 (sk) 1998-07-08
MY116824A (en) 2004-04-30
CZ288463B6 (en) 2001-06-13
CZ9602347A3 (en) 2001-06-13
JP2926257B2 (ja) 1999-07-28
DD298406A5 (de) 1992-02-20
NZ233646A (en) 1991-10-25
TW233301B (fr) 1994-11-01
CA2016765A1 (fr) 1990-11-15
YU92890A (sh) 1992-09-07
PL285175A1 (en) 1991-01-14
SK279253B6 (sk) 1998-08-05
PL163999B1 (pl) 1994-06-30
ZA903662B (en) 1991-01-30
SK237290A3 (en) 1998-07-08

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