CA1235032A - Syringe for extrusion of wetted, particulate material - Google Patents
Syringe for extrusion of wetted, particulate materialInfo
- Publication number
- CA1235032A CA1235032A CA000434170A CA434170A CA1235032A CA 1235032 A CA1235032 A CA 1235032A CA 000434170 A CA000434170 A CA 000434170A CA 434170 A CA434170 A CA 434170A CA 1235032 A CA1235032 A CA 1235032A
- Authority
- CA
- Canada
- Prior art keywords
- barrel
- syringe
- mass
- dispensing syringe
- piston
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Abstract
A B S T R A C T
The invention relates to a syringe for extrusion of a semi-plastic, particulate mass comprising a barrel of flexible material having one or more longitudinal slits therein and provided at its upper end with a piston with means for making positive engagement with a plunger rod, the barrel being optionally fitted with a closure plug.
The invention relates to a syringe for extrusion of a semi-plastic, particulate mass comprising a barrel of flexible material having one or more longitudinal slits therein and provided at its upper end with a piston with means for making positive engagement with a plunger rod, the barrel being optionally fitted with a closure plug.
Description
This invention relates to a syringe useful in extruding a simplistic, particulate mass therefrom The use of two component mixing syrinxes for dissolving a solid medicament in a liquid delineate prior to injection ox the solution is well known in medical practice.
on example of such syringes is illustrated by U.S. Patent 4,060,082, which describes a syringe combination comprising a mixer/dispenser syringe, usually containing a solid medicament, which is connected via a collapsible connect-in sleeve to a carrier syringe, usually containing a liquid delineate used to dissolve the medicament in the mixer/
dispenser section When it is desired -to use the syringe, the two syringe sections are telescoped together thus forcing a Jill needle positioned between the two syringe sections to make a communicating connection between the mixer/dispenser and the carrier syringe sections, The liquid contents of the carrier section can then be ejected through the Jill needle into the mixer/dispenser section.
After the solid medicament has dissolved, a hypodermic needle is attached to the exit end of the mixer/dispenser section, a plunger is attached to a rubber piston closing the other end, and the liquid contents can then be ejected There are various means for making connection between two sections of a two component mixing syringe, the collapsible sleeve and iilliny needle described in the above-noted patent being one such means. Another means of achieving such inter-connection is illustrated in U.S. Patent 4~046l145 which describes a Lure likelier joint two-part unit, I,.
~23~3~
I
However, syringes for dispensing liquids are difficult to use in the extrusion of simplistic, part-curate masses, and may in some cases be inoperative ton such purpose. While the prior art is thus instructive on the problem of mixing two components and dispensing a resulting solution in liquid form, so far as is known, -the art is silent on the problem of mixing two or more components within a syringe barrel, so as to form a semi-plastic, particulate mass, for extrusion thereof D
It has been found that particulate matter, such a particulate ceramic material used in dental restorative procedures, even when wetted, tends to jam in the barrel when extruded from conventional syringes, perhaps due to frictional resistance between the sharp edges of the particles and the syringe barrel wall. We have discovered that the problem can be overcome by equipping the syringe barrel, which is fabricated of a flexible plastic material, with one or more longitudinal slits in the barrel. The provision of such slits has the effect of providing sufficient relief from the frictional resistance to permit unobstructed extrusion of particulate material from the barrel.
The present invention therefore is directed, in one aspect to a dispensing syringe useful for extruding a semi-plastic, particulate mass therefrom which comprises to a barrel of flexible plastic material having one or more longitudinal slits therein and which is provided at its upper end with (B) a piston having means for making positive engagement with (C) a plunger rod, the barrel being optionally fitted with (D) a closure plug The syringe may/ if desired, be preluded with a particulate component which/ on admixture with a liquid component, would produce a semi-plastic, extrudable mass One can use the said syringe in dental restorative processes In order to fully describe the invention herein and the manner of using it, it will be necessary to use certain portions of a syringe unit as points of reference to illustrate relative movements of the parts of the syringe I I
I
Therefore, throughout this specification and in the appended claims, the terms "lower" and "downwards" are intended to refer to the exit end of the syringe and its various associated parts as assembled or oriented in the syringe for extruding use, and the terms "upper" and "upward" are intended to refer to the opposite or head end of the same.
The invention is described hereinbelow with reference to the accompanying drawings wherein:
Figure 1 is a perspective view of the barrel, closure plug, plunger and piston units which comprise the principal elements of the syringe.
Figure 2 is a longitudinal view in partial cross section of the syringe as assembled prior to use Figure 3 is a longitudinal view in partial cross section of the assembled syringe in use.
The invention will now be described in detail with reference to the foregoing figures where like numerals are used to designate like parts.
Figure 1 shows the various principal elements of the syringe including the syringe barrel unit lo hazing a longitudinal slit 11 and equipped with finger grip head 12.
The barrel is fitted with a closure plug 13 which fits over the lower end of the barrel to prevent a particulate come potent of an extrudable mass from falling out of the end of the barrel. The syringe is also equipped with a plunger rod unit 14 having a thumb plate 15 at its upper end. The lower end of the plunger rod is equipped with a piston 16 which is slid able within the bore of the syringe barrel 10.
The plunger rod I and the piston 16 are preferably non-unitary parts, made of different materials and joined together by any means effective for making positive inter-connection, such as by a ball and socket connection in which a spheroid or elongate spheroid shape is used on the lower end of the plunger rod -to mate with a cavity of corresponding shape molded into the piston.
Figure 2 shows the principal elements of the syringe as they would appear when assembled prior to load I 03~
in with any component of an extrudable mass and prior to use, and Figure 3 shows the principal elements of the syringe containing an extrudable mass lo as the syringe would appear in use The syringe provided by the invention would be particularly useful in the field of dental surgery and especially in alveolar ridge augmentation procedures in edentulous patients. In such patients, over a period of time the alveolar ridge undergoes gradual bone resorption lo with consequent diminution in height of the alveolar ridge.
This process in turn produces a condition whereby dentures must be remolded and fitted to a continuously changing gum shape. The problem can be alleviated by restructuring the alveolar ridge with a material that is capable of bonding to osseous tissue, is non-resorbable and provides a matrix for new bone growth. Materials which have been found use-fur for this purpose are certain ceramic materials, in-eluding especially hydroxylapatite~ The process for pro-paring hydroxylapatite and the use of this material in dental restorative processes are disclosed in U.S.
Patent ~,097,935.
In using the syringe of the present invention in dental restorative procedures as described above, the barrel 10 of the syringe would be filled with the powdered or granulated ceramic material, erg. hydroxylapatite.
The slit if in the barrel is formed either by merely slitting the barrel wall after fabrication of the latter or by molding the slit into the barrel at the time of fabrication. The purpose of the slit is to provide a means for slight circumferential expansion of the barrel along its operative length as the piston moves thrilling in order to thereby slightly relieve the frictional resistance between the particulate material and the barrel wall. This construction permits unobstructed extrusion of the particulate material while still preserving the general cross sectional form of the extruded mass In order to achieve this objective, therefore the length ~L~$r-~P3 of the slit preferably corresponds approximately to the length of -the extrudable mass as it would appear when packed into the syringe barrel for use That is the slit extends up to, but preferably not beyond, the piston as it would be positioned in the barrel prior to use In preparing the syringe for use, the dental surgeon Gould insert the tip of the syringe in saline, distilled water or other suitable delivery fluid, and by withdrawing the plunger rod, draw the liquid up into the barrel of the syringe through the slit 11, thus producing a wetted, extrudable mass of the granular ceramic material.
Prior to preparation of the ceramic/delivery fluid, for example a ceramic/saline mixture as described above, the surgeon would intraoral prepare a mucoperiosteal tunnel through a vertical incision on the lateral aspect of the patient's jaw The closure plug 13 would then be removed from the syringe, and the barrel thereof inserted through the incision into the tunnel formed adjacent the alveolar ridge. By slowly withdrawing the syringe barrel from the tunnel while extruding the syringe contents by downward pressure on the plunger the extrudable, wetted ceramic mass would be deposited into the prepared mucoperiosteal tunnel adjacent the alveolar ridge. Ultimate-lye the ceramic mass will bond to the cortical bone thereby augmenting the alveolar ridge.
When used in alveolar ridge augmentation pro-seeders as described above, the syringe barrel 11 con advantageously be supplied with appropriate indicia as an aid in determining the amount and the rate of extrusion of the plasticized material from the barrel The syringe of the invention is suitably made of an appropriate plastic material which, when used in dental restorative processes, can be sterilized by autoclaving, gas or irradiation. Thus the barrel and finger grip can be made of polyethylene or polypropylene, while the plunger rod is suitably made of styrenes or nylon The closure plug and the piston can be made of either the same or different I I
flexible material such as a natural or synthetic elastomers or rubber, for example a vinyl or bottle rubber t including brominated or chlorinated bottle rubbers or neoprene.
The means for making positive inter connection between the plunger rod and the piston has been described herein, for purposes of illustration, in terms of a spheroid or elongate spheroid shape on the end ox the plunger rod with a cavity of corresponding shape molded into -the piston I-Jowever, any of various means well known in the art for LO making such inter-connection that would be operative for the stated purpose are considered to be within the gambit of -the invention. Such alternative means ox effecting inter connection include, for example, a bayonet, or push-and-turn, connection, or a screw-threaded tip and socket on the plunger and piston, respectively. These, and other similarly effective interconnecting means, are thus the full equivalents of the ball and socket inter-connection specifically described herein
on example of such syringes is illustrated by U.S. Patent 4,060,082, which describes a syringe combination comprising a mixer/dispenser syringe, usually containing a solid medicament, which is connected via a collapsible connect-in sleeve to a carrier syringe, usually containing a liquid delineate used to dissolve the medicament in the mixer/
dispenser section When it is desired -to use the syringe, the two syringe sections are telescoped together thus forcing a Jill needle positioned between the two syringe sections to make a communicating connection between the mixer/dispenser and the carrier syringe sections, The liquid contents of the carrier section can then be ejected through the Jill needle into the mixer/dispenser section.
After the solid medicament has dissolved, a hypodermic needle is attached to the exit end of the mixer/dispenser section, a plunger is attached to a rubber piston closing the other end, and the liquid contents can then be ejected There are various means for making connection between two sections of a two component mixing syringe, the collapsible sleeve and iilliny needle described in the above-noted patent being one such means. Another means of achieving such inter-connection is illustrated in U.S. Patent 4~046l145 which describes a Lure likelier joint two-part unit, I,.
~23~3~
I
However, syringes for dispensing liquids are difficult to use in the extrusion of simplistic, part-curate masses, and may in some cases be inoperative ton such purpose. While the prior art is thus instructive on the problem of mixing two components and dispensing a resulting solution in liquid form, so far as is known, -the art is silent on the problem of mixing two or more components within a syringe barrel, so as to form a semi-plastic, particulate mass, for extrusion thereof D
It has been found that particulate matter, such a particulate ceramic material used in dental restorative procedures, even when wetted, tends to jam in the barrel when extruded from conventional syringes, perhaps due to frictional resistance between the sharp edges of the particles and the syringe barrel wall. We have discovered that the problem can be overcome by equipping the syringe barrel, which is fabricated of a flexible plastic material, with one or more longitudinal slits in the barrel. The provision of such slits has the effect of providing sufficient relief from the frictional resistance to permit unobstructed extrusion of particulate material from the barrel.
The present invention therefore is directed, in one aspect to a dispensing syringe useful for extruding a semi-plastic, particulate mass therefrom which comprises to a barrel of flexible plastic material having one or more longitudinal slits therein and which is provided at its upper end with (B) a piston having means for making positive engagement with (C) a plunger rod, the barrel being optionally fitted with (D) a closure plug The syringe may/ if desired, be preluded with a particulate component which/ on admixture with a liquid component, would produce a semi-plastic, extrudable mass One can use the said syringe in dental restorative processes In order to fully describe the invention herein and the manner of using it, it will be necessary to use certain portions of a syringe unit as points of reference to illustrate relative movements of the parts of the syringe I I
I
Therefore, throughout this specification and in the appended claims, the terms "lower" and "downwards" are intended to refer to the exit end of the syringe and its various associated parts as assembled or oriented in the syringe for extruding use, and the terms "upper" and "upward" are intended to refer to the opposite or head end of the same.
The invention is described hereinbelow with reference to the accompanying drawings wherein:
Figure 1 is a perspective view of the barrel, closure plug, plunger and piston units which comprise the principal elements of the syringe.
Figure 2 is a longitudinal view in partial cross section of the syringe as assembled prior to use Figure 3 is a longitudinal view in partial cross section of the assembled syringe in use.
The invention will now be described in detail with reference to the foregoing figures where like numerals are used to designate like parts.
Figure 1 shows the various principal elements of the syringe including the syringe barrel unit lo hazing a longitudinal slit 11 and equipped with finger grip head 12.
The barrel is fitted with a closure plug 13 which fits over the lower end of the barrel to prevent a particulate come potent of an extrudable mass from falling out of the end of the barrel. The syringe is also equipped with a plunger rod unit 14 having a thumb plate 15 at its upper end. The lower end of the plunger rod is equipped with a piston 16 which is slid able within the bore of the syringe barrel 10.
The plunger rod I and the piston 16 are preferably non-unitary parts, made of different materials and joined together by any means effective for making positive inter-connection, such as by a ball and socket connection in which a spheroid or elongate spheroid shape is used on the lower end of the plunger rod -to mate with a cavity of corresponding shape molded into the piston.
Figure 2 shows the principal elements of the syringe as they would appear when assembled prior to load I 03~
in with any component of an extrudable mass and prior to use, and Figure 3 shows the principal elements of the syringe containing an extrudable mass lo as the syringe would appear in use The syringe provided by the invention would be particularly useful in the field of dental surgery and especially in alveolar ridge augmentation procedures in edentulous patients. In such patients, over a period of time the alveolar ridge undergoes gradual bone resorption lo with consequent diminution in height of the alveolar ridge.
This process in turn produces a condition whereby dentures must be remolded and fitted to a continuously changing gum shape. The problem can be alleviated by restructuring the alveolar ridge with a material that is capable of bonding to osseous tissue, is non-resorbable and provides a matrix for new bone growth. Materials which have been found use-fur for this purpose are certain ceramic materials, in-eluding especially hydroxylapatite~ The process for pro-paring hydroxylapatite and the use of this material in dental restorative processes are disclosed in U.S.
Patent ~,097,935.
In using the syringe of the present invention in dental restorative procedures as described above, the barrel 10 of the syringe would be filled with the powdered or granulated ceramic material, erg. hydroxylapatite.
The slit if in the barrel is formed either by merely slitting the barrel wall after fabrication of the latter or by molding the slit into the barrel at the time of fabrication. The purpose of the slit is to provide a means for slight circumferential expansion of the barrel along its operative length as the piston moves thrilling in order to thereby slightly relieve the frictional resistance between the particulate material and the barrel wall. This construction permits unobstructed extrusion of the particulate material while still preserving the general cross sectional form of the extruded mass In order to achieve this objective, therefore the length ~L~$r-~P3 of the slit preferably corresponds approximately to the length of -the extrudable mass as it would appear when packed into the syringe barrel for use That is the slit extends up to, but preferably not beyond, the piston as it would be positioned in the barrel prior to use In preparing the syringe for use, the dental surgeon Gould insert the tip of the syringe in saline, distilled water or other suitable delivery fluid, and by withdrawing the plunger rod, draw the liquid up into the barrel of the syringe through the slit 11, thus producing a wetted, extrudable mass of the granular ceramic material.
Prior to preparation of the ceramic/delivery fluid, for example a ceramic/saline mixture as described above, the surgeon would intraoral prepare a mucoperiosteal tunnel through a vertical incision on the lateral aspect of the patient's jaw The closure plug 13 would then be removed from the syringe, and the barrel thereof inserted through the incision into the tunnel formed adjacent the alveolar ridge. By slowly withdrawing the syringe barrel from the tunnel while extruding the syringe contents by downward pressure on the plunger the extrudable, wetted ceramic mass would be deposited into the prepared mucoperiosteal tunnel adjacent the alveolar ridge. Ultimate-lye the ceramic mass will bond to the cortical bone thereby augmenting the alveolar ridge.
When used in alveolar ridge augmentation pro-seeders as described above, the syringe barrel 11 con advantageously be supplied with appropriate indicia as an aid in determining the amount and the rate of extrusion of the plasticized material from the barrel The syringe of the invention is suitably made of an appropriate plastic material which, when used in dental restorative processes, can be sterilized by autoclaving, gas or irradiation. Thus the barrel and finger grip can be made of polyethylene or polypropylene, while the plunger rod is suitably made of styrenes or nylon The closure plug and the piston can be made of either the same or different I I
flexible material such as a natural or synthetic elastomers or rubber, for example a vinyl or bottle rubber t including brominated or chlorinated bottle rubbers or neoprene.
The means for making positive inter connection between the plunger rod and the piston has been described herein, for purposes of illustration, in terms of a spheroid or elongate spheroid shape on the end ox the plunger rod with a cavity of corresponding shape molded into -the piston I-Jowever, any of various means well known in the art for LO making such inter-connection that would be operative for the stated purpose are considered to be within the gambit of -the invention. Such alternative means ox effecting inter connection include, for example, a bayonet, or push-and-turn, connection, or a screw-threaded tip and socket on the plunger and piston, respectively. These, and other similarly effective interconnecting means, are thus the full equivalents of the ball and socket inter-connection specifically described herein
Claims (6)
1. A dental restorative dispensing syringe for ex-truding a wetted particulate mass therefrom which com-prises: (A) a barrel of flexible plastic material having at least one longitudinal slit therein at its open end in combination with (B) a piston slidable within the bore of said barrel and having means for making positive en-gagement with (C) a plunger rod, said slit being operative to allow said barrel to expand under the influence of said wetted particulate mass when said piston is extruding said mass, thereby reducing resistance.
2. A dispensing syringe according to claim 1, wherein said barrel has one longitudinal slit therein.
3. A dispensing syringe according to claim 1, which is fitted with a closure plug at its lower end.
4. A dispensing syringe according to claim 1, which is pre-loaded with the particulate material.
5. A dispensing syringe according to claim 4, wherein said particulate material is hydroxylapatite.
6. A dispensing syringe according to claim 4 or 5, wherein the length of the slit corresponds approximately to the length of the mass of particulate material in the syringe barrel prior to use.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40742482A | 1982-08-12 | 1982-08-12 | |
US407,424 | 1982-08-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1235032A true CA1235032A (en) | 1988-04-12 |
Family
ID=23612027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000434170A Expired CA1235032A (en) | 1982-08-12 | 1983-08-09 | Syringe for extrusion of wetted, particulate material |
Country Status (11)
Country | Link |
---|---|
US (1) | US4645488A (en) |
EP (1) | EP0106053B1 (en) |
JP (1) | JPS59105108U (en) |
KR (1) | KR840005668A (en) |
AU (1) | AU562631B2 (en) |
CA (1) | CA1235032A (en) |
DE (2) | DE3374172D1 (en) |
DK (1) | DK364683A (en) |
GR (1) | GR78911B (en) |
IE (1) | IE54384B1 (en) |
NZ (1) | NZ205033A (en) |
Families Citing this family (133)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8502933D0 (en) * | 1985-06-13 | 1985-06-13 | Leo Ab | Pipette |
US4806383A (en) * | 1987-02-24 | 1989-02-21 | Dentsply Gmbh | Method of applying opaque dental cermic material to a metal structure |
US4879136A (en) * | 1987-02-24 | 1989-11-07 | Dentsply G.M.B.H. | Method of applying opaque dental ceramic material to a metal structure |
US5108421A (en) * | 1990-10-01 | 1992-04-28 | Quinton Instrument Company | Insertion assembly and method of inserting a vessel plug into the body of a patient |
US5192300A (en) * | 1990-10-01 | 1993-03-09 | Quinton Instrument Company | Insertion assembly and method of inserting a vessel plug into the body of a patient |
US5252064A (en) * | 1991-02-19 | 1993-10-12 | Teledyne Industries, Inc. | Subgingival irrigator |
US6818008B1 (en) | 1992-01-07 | 2004-11-16 | Cch Associates, Inc. | Percutaneous puncture sealing method |
US6699261B1 (en) * | 1992-01-07 | 2004-03-02 | Cch Associates, Inc. | Blood vessel sealing system |
US5413571A (en) * | 1992-07-16 | 1995-05-09 | Sherwood Medical Company | Device for sealing hemostatic incisions |
US5431639A (en) * | 1993-08-12 | 1995-07-11 | Boston Scientific Corporation | Treating wounds caused by medical procedures |
DE9319007U1 (en) * | 1993-12-10 | 1995-04-06 | Muehlbauer Ernst | Storage syringe for viscous dental materials |
US20110015670A1 (en) * | 1994-05-20 | 2011-01-20 | Sealing Solutions, Inc. | Percutaneous Puncture Sealing System |
US20050065549A1 (en) * | 1997-09-12 | 2005-03-24 | Cates Christopher U. | Percutaneous puncture sealing system |
US5557905A (en) * | 1995-01-31 | 1996-09-24 | Harding; Kay J. | Bit for administering animal medication |
US5649959A (en) * | 1995-02-10 | 1997-07-22 | Sherwood Medical Company | Assembly for sealing a puncture in a vessel |
US6071301A (en) * | 1998-05-01 | 2000-06-06 | Sub Q., Inc. | Device and method for facilitating hemostasis of a biopsy tract |
US6071300A (en) * | 1995-09-15 | 2000-06-06 | Sub-Q Inc. | Apparatus and method for percutaneous sealing of blood vessel punctures |
US6183497B1 (en) | 1998-05-01 | 2001-02-06 | Sub-Q, Inc. | Absorbable sponge with contrasting agent |
US6162192A (en) * | 1998-05-01 | 2000-12-19 | Sub Q, Inc. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
AU740072B2 (en) | 1996-08-06 | 2001-10-25 | Tyco Group S.A.R.L. | Insertion assembly and method of inserting a hemostatic closure device into an incision |
US6003566A (en) * | 1998-02-26 | 1999-12-21 | Becton Dickinson And Company | Vial transferset and method |
US7625352B1 (en) | 1998-05-01 | 2009-12-01 | Sub-Q, Inc. | Depth and puncture control for system for hemostasis of blood vessel |
US6200328B1 (en) | 1998-05-01 | 2001-03-13 | Sub Q, Incorporated | Device and method for facilitating hemostasis of a biopsy tract |
US20010045575A1 (en) * | 1998-05-01 | 2001-11-29 | Mark Ashby | Device and method for facilitating hemostasis of a biopsy tract |
US6610026B2 (en) | 1998-05-01 | 2003-08-26 | Sub-Q, Inc. | Method of hydrating a sponge material for delivery to a body |
US6315753B1 (en) | 1998-05-01 | 2001-11-13 | Sub-Q, Inc. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
CA2317661C (en) * | 1998-11-20 | 2008-04-15 | Medical Industries Corp. | Hemostatic material insertion device |
WO2000047115A1 (en) | 1999-02-10 | 2000-08-17 | Sub-Q, Inc. | Device and method for facilitating hemostasis of a biopsy tract |
US6123683A (en) * | 1999-06-22 | 2000-09-26 | Tri-State Hospital Supply Corporation | Pill delivery apparatus |
IT1316440B1 (en) * | 1999-07-05 | 2003-04-22 | Inge Spa | CANNULA DISPENSER OF MEDICINAL OINTMENTS. |
US7695492B1 (en) | 1999-09-23 | 2010-04-13 | Boston Scientific Scimed, Inc. | Enhanced bleed back system |
US6984219B2 (en) | 1999-09-23 | 2006-01-10 | Mark Ashby | Depth and puncture control for blood vessel hemostasis system |
US6540735B1 (en) | 2000-05-12 | 2003-04-01 | Sub-Q, Inc. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
WO2002005865A2 (en) * | 2000-07-14 | 2002-01-24 | Sub-Q, Inc. | Sheath-mounted arterial plug delivery device |
US7201725B1 (en) | 2000-09-25 | 2007-04-10 | Sub-Q, Inc. | Device and method for determining a depth of an incision |
WO2002087636A1 (en) | 2001-03-12 | 2002-11-07 | Sub-Q, Inc. | Methods for sterilizing cross-linked gelatin compositions |
US8187625B2 (en) | 2001-03-12 | 2012-05-29 | Boston Scientific Scimed, Inc. | Cross-linked gelatin composition comprising a wetting agent |
US7029489B1 (en) | 2001-05-18 | 2006-04-18 | Sub-Q, Inc. | System and method for delivering hemostasis promoting material to a blood vessel puncture site |
US7008440B2 (en) | 2001-11-08 | 2006-03-07 | Sub-Q, Inc. | System and method for delivering hemostasis promoting material to a blood vessel puncture site by fluid pressure |
US6863680B2 (en) | 2001-11-08 | 2005-03-08 | Sub-Q, Inc. | System and method for delivering hemostasis promoting material to a blood vessel puncture site by fluid pressure |
FR2829690B1 (en) * | 2001-09-19 | 2003-12-19 | Inoteb | DEVICE FOR PLACING A BIOMATERIAL |
US7192436B2 (en) * | 2001-11-08 | 2007-03-20 | Sub-Q, Inc. | Pledget-handling system and method for delivering hemostasis promoting material to a blood vessel puncture site by fluid pressure |
US7037323B2 (en) * | 2001-11-08 | 2006-05-02 | Sub-Q, Inc. | Pledget-handling system and method for delivering hemostasis promoting material to a blood vessel puncture site by fluid pressure |
US7025748B2 (en) * | 2001-11-08 | 2006-04-11 | Boston Scientific Scimed, Inc. | Sheath based blood vessel puncture locator and depth indicator |
US7037322B1 (en) | 2001-11-08 | 2006-05-02 | Sub-Q, Inc. | System and method for delivering hemostasis promoting material to a blood vessel puncture with a staging tube |
US7217252B2 (en) * | 2002-06-14 | 2007-05-15 | Mcneil-Ppc, Inc. | Applicator device for medicated materials |
US7717873B2 (en) * | 2002-06-14 | 2010-05-18 | Mcneil-Ppc, Inc. | Applicator device for suppositories and the like |
US7198612B2 (en) * | 2002-06-14 | 2007-04-03 | Mcneil-Ppc, Inc. | Applicator device for suppositories and the like |
US7104968B2 (en) * | 2002-06-14 | 2006-09-12 | Mcneil-Ppc, Inc. | Applicator device for suppositories and the like |
US20040102730A1 (en) * | 2002-10-22 | 2004-05-27 | Davis Thomas P. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
US7455680B1 (en) | 2002-11-04 | 2008-11-25 | Boston Scientific Scimed, Inc. | Apparatus and method for inhibiting blood loss |
US8317821B1 (en) | 2002-11-04 | 2012-11-27 | Boston Scientific Scimed, Inc. | Release mechanism |
US7955353B1 (en) | 2002-11-04 | 2011-06-07 | Sub-Q, Inc. | Dissolvable closure device |
US7147468B2 (en) * | 2002-12-31 | 2006-12-12 | Water Pik, Inc. | Hand held oral irrigator |
WO2004075727A2 (en) * | 2003-02-21 | 2004-09-10 | Osteobiologics, Inc. | Bone and cartilage implant delivery device |
US10610406B2 (en) * | 2004-07-21 | 2020-04-07 | Vanderbilt University | Drug delivery device and applications of same |
US7909833B2 (en) * | 2003-09-29 | 2011-03-22 | Depuy Acromed, Inc. | Vertebroplasty device having a flexible plunger |
CN1925882A (en) * | 2003-11-15 | 2007-03-07 | 梅德拉股份有限公司 | Catheter for diagnostic imaging and therapeutic procedures |
US7875043B1 (en) | 2003-12-09 | 2011-01-25 | Sub-Q, Inc. | Cinching loop |
US7513901B2 (en) * | 2005-05-19 | 2009-04-07 | Warsaw Orthopedic, Inc. | Graft syringe assembly |
US20070203439A1 (en) | 2006-02-24 | 2007-08-30 | Water Pik, Inc. | Water jet unit and handle |
US7547300B2 (en) * | 2006-04-12 | 2009-06-16 | Icu Medical, Inc. | Vial adaptor for regulating pressure |
US7670141B2 (en) | 2006-07-07 | 2010-03-02 | Water Pik, Inc. | Oral irrigator |
US8876754B2 (en) * | 2006-08-31 | 2014-11-04 | Bayer Medical Care Inc. | Catheter with filtering and sensing elements |
USD802120S1 (en) | 2007-02-27 | 2017-11-07 | Water Pik, Inc. | Tip for oral irrigator |
US20090054906A1 (en) * | 2007-08-24 | 2009-02-26 | Zimmer Orthobiologics, Inc. | Medical device and method for delivering an implant to an anatomical site |
US20100190132A1 (en) | 2009-01-28 | 2010-07-29 | Water Pik, Inc. | Oral irrigator tip |
US20100249753A1 (en) * | 2009-02-25 | 2010-09-30 | Gaisser David M | Vented syringe system and method for the containment, mixing and ejection of wetted particulate material |
US10258442B2 (en) | 2009-03-20 | 2019-04-16 | Water Pik, Inc. | Oral irrigator appliance with radiant energy delivery for bactericidal effect |
USD629884S1 (en) | 2009-12-16 | 2010-12-28 | Water Pik, Inc. | Powered irrigator for sinus cavity rinse |
US9061096B2 (en) | 2009-12-16 | 2015-06-23 | Water Pik, Inc. | Powered irrigator for sinus cavity rinse |
US8435305B2 (en) | 2010-08-31 | 2013-05-07 | Zimmer, Inc. | Osteochondral graft delivery device and uses thereof |
USD670373S1 (en) | 2010-12-16 | 2012-11-06 | Water Pik, Inc. | Powered irrigator for sinus cavity rinse |
US10105201B2 (en) | 2012-10-11 | 2018-10-23 | Water Pik, Inc. | Interdental cleaner using water supply |
USD707350S1 (en) | 2012-10-11 | 2014-06-17 | Water Pik, Inc. | Handheld water flosser |
US9642677B2 (en) | 2013-03-14 | 2017-05-09 | Water Pik, Inc. | Oral irrigator with massage mode |
USD717427S1 (en) | 2013-03-14 | 2014-11-11 | Water Pik, Inc. | Handle for water flosser |
USD714929S1 (en) | 2013-03-14 | 2014-10-07 | Water Pik, Inc. | Base for water flosser |
USD725770S1 (en) | 2013-03-14 | 2015-03-31 | Water Pik, Inc. | Reservoir for water flosser |
USD788907S1 (en) | 2013-03-14 | 2017-06-06 | Water Pik, Inc. | Water flosser base unit with reservoir lid |
KR101824377B1 (en) | 2013-11-27 | 2018-01-31 | 워어터 피이크, 인코포레이티드 | Oral irrigator with slide pause switch |
US9980793B2 (en) | 2013-11-27 | 2018-05-29 | Water Pik, Inc. | Oral hygiene system |
CN203693808U (en) | 2013-12-12 | 2014-07-09 | 洁碧有限公司 | Dental water sprayer |
USD772396S1 (en) | 2014-12-01 | 2016-11-22 | Water Pik, Inc. | Handheld oral irrigator |
USD772397S1 (en) | 2014-12-01 | 2016-11-22 | Water Pik, Inc. | Oral irrigator with a charging device |
CN205586102U (en) | 2014-12-01 | 2016-09-21 | 洁碧有限公司 | Waterproof wireless oral cavity flusher |
USD780908S1 (en) | 2015-11-03 | 2017-03-07 | Water Pik, Inc. | Handheld oral irrigator |
USD822196S1 (en) | 2016-01-14 | 2018-07-03 | Water Pik, Inc. | Oral irrigator |
USD786422S1 (en) | 2016-01-25 | 2017-05-09 | Water Pik, Inc. | Oral irrigator |
USD804018S1 (en) | 2016-07-19 | 2017-11-28 | Water Pik, Inc. | Base for an oral irrigator |
USD783809S1 (en) | 2016-01-25 | 2017-04-11 | Water Pik, Inc. | Oral irrigator handle |
US10835356B2 (en) | 2016-01-25 | 2020-11-17 | Water Pik, Inc. | Swivel assembly for oral irrigator handle |
USD782656S1 (en) | 2016-01-25 | 2017-03-28 | Water Pik, Inc. | Oral irrigator |
USD802747S1 (en) | 2016-07-19 | 2017-11-14 | Water Pik, Inc. | Reservoir for oral irrigator |
USD796028S1 (en) | 2016-07-19 | 2017-08-29 | Water Pik, Inc. | Oral irrigator |
USD819956S1 (en) | 2016-01-25 | 2018-06-12 | Water Pik, Inc. | Kit bag |
CN114732551A (en) | 2016-01-25 | 2022-07-12 | 洁碧有限公司 | Reduced form factor oral irrigator |
USD794773S1 (en) | 2016-07-19 | 2017-08-15 | Water Pik, Inc. | Oral irrigator |
USD804016S1 (en) | 2016-02-05 | 2017-11-28 | Water Pik, Inc. | Handheld oral irrigator |
USD783810S1 (en) | 2016-02-22 | 2017-04-11 | Water Pik, Inc. | Handle for an oral irrigator |
USD809650S1 (en) | 2016-02-22 | 2018-02-06 | Water Pik, Inc. | Oral irrigator |
USD782657S1 (en) | 2016-03-02 | 2017-03-28 | Water Pik, Inc. | Oral irrigator handle |
USD802119S1 (en) | 2016-03-02 | 2017-11-07 | Water Pik, Inc. | Oral irrigator |
AU2017225965B2 (en) | 2016-03-02 | 2020-11-05 | Water Pik, Inc. | Actuation assembly for an oral irrigator |
USD807822S1 (en) | 2016-07-19 | 2018-01-16 | Water Pik, Inc. | Power supply cartridge |
USD809651S1 (en) | 2016-07-19 | 2018-02-06 | Water Pik, Inc. | Combination base and reservoir for an oral irrigator |
USD832420S1 (en) | 2016-12-15 | 2018-10-30 | Water Pik, Inc. | Oral irrigator base |
USD833600S1 (en) | 2016-12-15 | 2018-11-13 | Water Pik, Inc. | Oral irrigator reservoir |
USD832418S1 (en) | 2016-12-15 | 2018-10-30 | Water Pik, Inc. | Oral irrigator base |
WO2018112416A1 (en) | 2016-12-15 | 2018-06-21 | Water Pik, Inc. | Pause valve and swivel assemblies for oral irrigator handle |
USD822825S1 (en) | 2016-12-15 | 2018-07-10 | Water Pik, Inc. | Oral irrigator unit |
JP7146762B2 (en) | 2016-12-15 | 2022-10-04 | ウォーター ピック インコーポレイテッド | Oral irrigator with magnetic attachment |
USD867579S1 (en) | 2016-12-15 | 2019-11-19 | Water Pik, Inc. | Oral irrigator unit |
USD822826S1 (en) | 2016-12-15 | 2018-07-10 | Water Pik, Inc. | Oral irrigator base |
USD840022S1 (en) | 2016-12-15 | 2019-02-05 | Water Pik, Inc. | Oral irrigator handle |
USD834180S1 (en) | 2016-12-15 | 2018-11-20 | Water Pik, Inc. | Oral irrigator base |
USD829886S1 (en) | 2016-12-15 | 2018-10-02 | Water Pik, Inc. | Oral irrigator base |
USD832419S1 (en) | 2016-12-15 | 2018-10-30 | Water Pik, Inc. | Oral irrigator unit |
USD825741S1 (en) | 2016-12-15 | 2018-08-14 | Water Pik, Inc. | Oral irrigator handle |
USD840023S1 (en) | 2016-12-15 | 2019-02-05 | Water Pik, Inc. | Oral irrigator reservoir |
USD839409S1 (en) | 2016-12-15 | 2019-01-29 | Water Pik, Inc. | Oral irrigator unit |
USD833000S1 (en) | 2016-12-15 | 2018-11-06 | Water Pik, Inc. | Oral irrigator unit |
USD829887S1 (en) | 2017-02-06 | 2018-10-02 | Water Pik, Inc. | Oral irrigator reservoir |
USD833602S1 (en) | 2017-02-06 | 2018-11-13 | Water Pik, Inc. | Oral irrigator base |
USD833601S1 (en) | 2017-02-06 | 2018-11-13 | Water Pik, Inc. | Oral irrigator |
USD868243S1 (en) | 2018-03-16 | 2019-11-26 | Water Pik, Inc. | Oral irrigator tip |
USD877324S1 (en) | 2018-05-17 | 2020-03-03 | Water Pik, Inc. | Oral irrigator handle |
EP3669911A1 (en) * | 2018-12-18 | 2020-06-24 | SHL Medical AG | Medicament delivery device |
USD888936S1 (en) | 2019-02-22 | 2020-06-30 | Water Pik, Inc. | Cordless water flosser |
USD889636S1 (en) | 2019-02-22 | 2020-07-07 | Water Pik, Inc. | Water flosser |
USD966498S1 (en) | 2020-09-15 | 2022-10-11 | Water Pik, Inc. | Oral irrigator |
USD1016274S1 (en) | 2021-02-16 | 2024-02-27 | Water Pik, Inc. | Oral irrigator |
RU210461U1 (en) * | 2022-01-11 | 2022-04-15 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации | Hemostatic applicator |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2754822A (en) * | 1954-02-15 | 1956-07-17 | Emelock Melvin | Instrument for the administration of suppositories |
US3424158A (en) * | 1966-06-21 | 1969-01-28 | Jules Silver | Combination plastic mold,suppository package,dispenser and method for providing and using the same |
US3633585A (en) * | 1969-04-17 | 1972-01-11 | Cutter Lab | Catheter |
US3960153A (en) * | 1969-09-30 | 1976-06-01 | Jane Towne Carey | Apparatus for the palliative treatment of pleural effusions |
BE792846A (en) * | 1971-12-17 | 1973-06-15 | Procter & Gamble | NEW HYGIENIC BUFFER INSERTION DEVICE |
US3934584A (en) * | 1973-09-26 | 1976-01-27 | Corio Nicholas N | Balling gun |
US3828767A (en) * | 1973-10-29 | 1974-08-13 | Fenton J | Angiographic and arteriographic catherters |
DE2421928B2 (en) * | 1974-05-07 | 1980-08-07 | A. Kettenbach Fabrik Chemischer Erzeugnisse Dental-Spezialitaeten Gmbh & Co Kg, 6345 Eschenburg | Dosing device designed as a pack for flowable impression materials for the dental practice and dental laboratories |
US3918452A (en) * | 1974-08-01 | 1975-11-11 | Edward Cornfeld | Tampons impregnated with contraceptive compositions |
US4046145A (en) * | 1976-06-29 | 1977-09-06 | American Hospital Supply Corporation | Syringe connector |
US4060082A (en) * | 1976-08-16 | 1977-11-29 | Mpl, Inc. | Dual-ingredient medication dispenser |
US4280500A (en) * | 1978-03-31 | 1981-07-28 | Kazuaki Ono | Tubular flexible medical instrument |
IT7822184V0 (en) * | 1978-06-27 | 1978-06-27 | Boschetti Enrica | PACKAGING FOR FUNGENT PASTIC SUBSTANCES ALSO FROM CYLINDER FOR THE EXPULSION OF THE SAME. |
US4318402A (en) * | 1979-07-12 | 1982-03-09 | Critikon, Inc | Liquid infusion catheter assembly |
CA1092927A (en) * | 1979-12-28 | 1981-01-06 | Allentyne Limited | Hemodialysis cannula for subclavian insertion |
US4551135A (en) * | 1981-06-22 | 1985-11-05 | Sterling Drug Inc. | Syringe for extrusion of semi-plastic material |
US4464176A (en) * | 1982-06-04 | 1984-08-07 | Mallinckrodt, Inc. | Blood vessel catheter for medicine delivery and method of manufacture |
US4545390A (en) * | 1982-09-22 | 1985-10-08 | C. R. Bard, Inc. | Steerable guide wire for balloon dilatation procedure |
US4540404A (en) * | 1983-01-19 | 1985-09-10 | Datascope Corp. | Balloon catheter with intrinsic introducer for percutaneous insertion into a blood vessel over a guide wire, and method of use |
US4571240A (en) * | 1983-08-12 | 1986-02-18 | Advanced Cardiovascular Systems, Inc. | Catheter having encapsulated tip marker |
US4573470A (en) * | 1984-05-30 | 1986-03-04 | Advanced Cardiovascular Systems, Inc. | Low-profile steerable intraoperative balloon dilitation catheter |
-
1983
- 1983-07-27 NZ NZ205033A patent/NZ205033A/en unknown
- 1983-08-01 AU AU17477/83A patent/AU562631B2/en not_active Ceased
- 1983-08-04 IE IE1847/83A patent/IE54384B1/en unknown
- 1983-08-09 KR KR1019830003717A patent/KR840005668A/en not_active Application Discontinuation
- 1983-08-09 CA CA000434170A patent/CA1235032A/en not_active Expired
- 1983-08-09 GR GR72176A patent/GR78911B/el unknown
- 1983-08-10 DE DE8383107915T patent/DE3374172D1/en not_active Expired
- 1983-08-10 JP JP1983124363U patent/JPS59105108U/en active Granted
- 1983-08-10 DK DK364683A patent/DK364683A/en unknown
- 1983-08-10 EP EP83107915A patent/EP0106053B1/en not_active Expired
- 1983-08-10 DE DE19838323058U patent/DE8323058U1/en not_active Expired
- 1983-11-30 US US06/556,725 patent/US4645488A/en not_active Expired - Fee Related
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IE54384B1 (en) | 1989-09-13 |
AU1747783A (en) | 1984-02-16 |
KR840005668A (en) | 1984-11-16 |
EP0106053A1 (en) | 1984-04-25 |
DE8323058U1 (en) | 1984-02-23 |
AU562631B2 (en) | 1987-06-18 |
DK364683D0 (en) | 1983-08-10 |
GR78911B (en) | 1984-10-02 |
JPS6311937Y2 (en) | 1988-04-06 |
DE3374172D1 (en) | 1987-12-03 |
NZ205033A (en) | 1986-07-11 |
DK364683A (en) | 1984-02-13 |
JPS59105108U (en) | 1984-07-14 |
US4645488A (en) | 1987-02-24 |
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