CA1217728A - Automatic installation for liquid chromatography - Google Patents
Automatic installation for liquid chromatographyInfo
- Publication number
- CA1217728A CA1217728A CA000437854A CA437854A CA1217728A CA 1217728 A CA1217728 A CA 1217728A CA 000437854 A CA000437854 A CA 000437854A CA 437854 A CA437854 A CA 437854A CA 1217728 A CA1217728 A CA 1217728A
- Authority
- CA
- Canada
- Prior art keywords
- column
- container
- eluent
- signal
- installation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000009434 installation Methods 0.000 title claims abstract description 35
- 238000004811 liquid chromatography Methods 0.000 title claims abstract description 7
- 239000003480 eluent Substances 0.000 claims abstract description 58
- 238000001514 detection method Methods 0.000 claims abstract description 24
- 238000002347 injection Methods 0.000 claims abstract description 22
- 239000007924 injection Substances 0.000 claims abstract description 22
- 238000004587 chromatography analysis Methods 0.000 claims abstract description 21
- 239000007788 liquid Substances 0.000 claims description 27
- 239000000523 sample Substances 0.000 claims description 26
- 230000000875 corresponding effect Effects 0.000 description 11
- 230000001276 controlling effect Effects 0.000 description 8
- 238000010586 diagram Methods 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 239000000470 constituent Substances 0.000 description 4
- 239000003990 capacitor Substances 0.000 description 3
- 238000012435 analytical chromatography Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 230000002452 interceptive effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 210000002381 plasma Anatomy 0.000 description 2
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical group CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 241001296096 Probles Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 238000005868 electrolysis reaction Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000003455 independent Effects 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000001702 transmitter Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/24—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the treatment of the fractions to be distributed
- B01D15/247—Fraction collectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/22—Injection in high pressure liquid systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Fluid Mechanics (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8216302A FR2533456A1 (fr) | 1982-09-28 | 1982-09-28 | Installation automatique pour chromatographie liquide |
| FR8216302 | 1982-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1217728A true CA1217728A (en) | 1987-02-10 |
Family
ID=9277809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000437854A Expired CA1217728A (en) | 1982-09-28 | 1983-09-28 | Automatic installation for liquid chromatography |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0107544B1 (enrdf_load_stackoverflow) |
| JP (1) | JPS5983053A (enrdf_load_stackoverflow) |
| CA (1) | CA1217728A (enrdf_load_stackoverflow) |
| DE (1) | DE3368530D1 (enrdf_load_stackoverflow) |
| DK (1) | DK161498C (enrdf_load_stackoverflow) |
| FR (1) | FR2533456A1 (enrdf_load_stackoverflow) |
| IE (1) | IE54651B1 (enrdf_load_stackoverflow) |
| NO (1) | NO159433C (enrdf_load_stackoverflow) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61215962A (ja) * | 1985-03-22 | 1986-09-25 | Yamazen Kk | フラクシヨンコレクタ− |
| JPS6396552A (ja) * | 1986-10-14 | 1988-04-27 | Suntory Ltd | 生体高分子の工業的分離法、その方法に使用する装置 |
| FR2705582B1 (fr) * | 1993-05-25 | 1995-06-30 | Commissariat Energie Atomique | Dispositif automatique de traitement par chromatographie sur colonne et détecteur de liquide utilisable dans un tel dispositif. |
| AUPM895494A0 (en) * | 1994-10-24 | 1994-11-17 | Vassett, Paul Andrew | Column guard |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2692820A (en) * | 1950-10-28 | 1954-10-26 | Upjohn Co | Method and means for effecting automatic fractionation |
| US3701609A (en) * | 1971-05-13 | 1972-10-31 | David G Bailey | Apparatus for automatically adding preselected patterns of eluent solutions to a chromatographic column and monitoring and collecting eluted fractions |
| US3826905A (en) * | 1971-10-27 | 1974-07-30 | Suomen Sokeri Oy | Methods and apparatus for providing automatic control of chromatographic fractionating processes |
| JPS5123360A (ja) * | 1974-08-15 | 1976-02-24 | Teijin Ltd | Yokoitotanchisochi |
| FR2388585A1 (fr) * | 1977-04-26 | 1978-11-24 | Elf Aquitaine | Separation et purification de proteines et/ou d'unites morphologiquement organisees (virus) par la chromatographie d'exclusion |
| US4116046A (en) * | 1977-08-05 | 1978-09-26 | Hoffmann-La Roche Inc. | Liquid chromatography system |
| DE3030069A1 (de) * | 1980-08-08 | 1982-03-11 | Philips Patentverwaltung Gmbh, 2000 Hamburg | Anordnung zur messung des elektrischen flaechenwiderstandes elektrisch leitender schichten |
-
1982
- 1982-09-28 FR FR8216302A patent/FR2533456A1/fr active Granted
-
1983
- 1983-09-22 IE IE2227/83A patent/IE54651B1/en not_active IP Right Cessation
- 1983-09-27 NO NO833481A patent/NO159433C/no unknown
- 1983-09-27 DE DE8383401880T patent/DE3368530D1/de not_active Expired
- 1983-09-27 EP EP83401880A patent/EP0107544B1/fr not_active Expired
- 1983-09-28 CA CA000437854A patent/CA1217728A/en not_active Expired
- 1983-09-28 JP JP58180089A patent/JPS5983053A/ja active Pending
- 1983-09-28 DK DK444983A patent/DK161498C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0107544A3 (en) | 1984-06-20 |
| EP0107544A2 (fr) | 1984-05-02 |
| DK444983D0 (da) | 1983-09-28 |
| DK444983A (da) | 1984-03-29 |
| NO159433C (no) | 1988-12-28 |
| IE54651B1 (en) | 1989-12-20 |
| DK161498B (da) | 1991-07-15 |
| NO833481L (no) | 1984-03-29 |
| JPS5983053A (ja) | 1984-05-14 |
| EP0107544B1 (fr) | 1986-12-30 |
| FR2533456A1 (fr) | 1984-03-30 |
| NO159433B (no) | 1988-09-19 |
| DK161498C (da) | 1991-12-23 |
| FR2533456B1 (enrdf_load_stackoverflow) | 1985-03-29 |
| DE3368530D1 (en) | 1987-02-05 |
| IE832227L (en) | 1984-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |