CA1209500A - Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction - Google Patents

Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction

Info

Publication number
CA1209500A
CA1209500A CA000422956A CA422956A CA1209500A CA 1209500 A CA1209500 A CA 1209500A CA 000422956 A CA000422956 A CA 000422956A CA 422956 A CA422956 A CA 422956A CA 1209500 A CA1209500 A CA 1209500A
Authority
CA
Canada
Prior art keywords
lens epithelial
epithelial cells
cells
monoclonal antibodies
human lens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000422956A
Other languages
English (en)
French (fr)
Inventor
Jared M. Emery
Dominic M. Lam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Original Assignee
Baylor College of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine
Application granted granted Critical
Publication of CA1209500A publication Critical patent/CA1209500A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CA000422956A 1982-03-05 1983-03-04 Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction Expired CA1209500A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/355,081 US4432751A (en) 1982-03-05 1982-03-05 Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction
US355,081 1982-03-05

Publications (1)

Publication Number Publication Date
CA1209500A true CA1209500A (en) 1986-08-12

Family

ID=23396159

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000422956A Expired CA1209500A (en) 1982-03-05 1983-03-04 Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction

Country Status (10)

Country Link
US (1) US4432751A (https=)
EP (1) EP0088606B1 (https=)
JP (2) JPS58192831A (https=)
CA (1) CA1209500A (https=)
DE (1) DE3372785D1 (https=)
DK (1) DK160562C (https=)
GR (1) GR77941B (https=)
IE (1) IE54702B1 (https=)
IL (1) IL69715A (https=)
ZA (1) ZA831168B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202252A (en) * 1982-03-05 1993-04-13 Houston Biotechnology Inc. Monoclonal antibodies against lens epithelial cells and methods for preventing proliferation of remnant lens epithelial cells after extracapsular extraction
EP0256344B1 (de) * 1986-08-18 1992-04-22 Wolfgang G.K. Dr. Müller-Lierheim Kontaktlinse
US5616122A (en) * 1986-11-04 1997-04-01 Baylor College Of Medicine Methods and compositions for preventing secondary cataracts
US5055291A (en) * 1986-11-04 1991-10-08 Baylor College Of Medicine Compositions for preventing secondary cataracts
DE3783211T2 (de) * 1986-11-04 1993-04-29 Baylor College Medicine Zusammensetzungen zur verhuetung sekundaeren grauen stars.
US4871350A (en) * 1986-11-04 1989-10-03 Baylor College Of Medicine Methods and compositions for preventing secondary cataracts
US4918165A (en) * 1987-07-16 1990-04-17 Ophthalmic Research Corporation Mitotic inhibitor and method for preventing posterior lens capsule opacification after extracapsular extraction
US4966577A (en) * 1988-03-16 1990-10-30 Allergan, Inc. Prevention of lens-related tissue growth in the eye
US4909784A (en) * 1988-03-25 1990-03-20 Seymour Dubroff Method for preventing clouding of posterior capsule after extracapsular cataract eye surgery
ATE126530T1 (de) * 1988-06-08 1995-09-15 Baylor College Medicine Monoklonale antikörper gegen linsenepithelzellen und methoden zur verhinderung des vermehrung übriggebliebener linsenepithelzellen nach extrakapsuläres extraktion.
DE3826399C2 (de) * 1988-08-03 2001-08-30 Wilhelm Ludwig Kraemer Reinigungsanlage für Waagen, insbesondere Kombinationswaagen
US5627162A (en) * 1990-01-11 1997-05-06 Gwon; Arlene E. Methods and means for control of proliferation of remnant cells following surgery
JPH0555847U (ja) * 1992-01-13 1993-07-27 三菱農機株式会社 脱穀機の受網目詰まり防止装置
US5375611A (en) * 1993-01-26 1994-12-27 Pharmacia Ab Method for preventing secondary cataract
US5876438A (en) * 1993-08-02 1999-03-02 Houston Biotechnology Incorporated Polymeric device for the delivery of immunotoxins for the prevention of secondary cataract
US5620013A (en) * 1994-10-21 1997-04-15 American Cyanamid Company Method for destroying residual lens epithelial cells
CA2187482A1 (en) * 1995-10-13 1997-04-14 Eri Inoue Pharmaceutical composition
US6106554A (en) * 1999-02-25 2000-08-22 Bausch & Lomb Surgical, Inc. Intraocular lens implants for the prevention of secondary cataracts
US6454802B1 (en) 2000-08-21 2002-09-24 Bausch & Lomb Incorporated Intraocular lens implant for the prevention of secondary cataracts
US6945971B1 (en) * 2004-07-19 2005-09-20 Gwon Arlene E Controlled ocular lens regeneration
US7252662B2 (en) * 2004-11-02 2007-08-07 Lenticular Research Group Llc Apparatus and processes for preventing or delaying one or more symptoms of presbyopia
AU2006213997A1 (en) 2005-02-19 2006-08-24 Lenticular Research Group Llc Apparatus and processes for preventing or delaying onset or progression of age-related cataract

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307082A (en) * 1979-07-10 1981-12-22 New York University Method for the extraction of a factor that mediates contact inhibition of cell growth
US4342828A (en) * 1979-07-20 1982-08-03 Morinaga Milk Industry Co., Ltd. Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells
US4349528A (en) * 1979-11-21 1982-09-14 The Wistar Institute Monocolonal hybridoma antibody specific for high molecular weight carcinoembryonic antigen

Also Published As

Publication number Publication date
EP0088606A3 (en) 1984-03-28
ZA831168B (en) 1983-11-30
JPH05184358A (ja) 1993-07-27
EP0088606A2 (en) 1983-09-14
GR77941B (https=) 1984-09-25
IL69715A (en) 1988-06-30
DE3372785D1 (en) 1987-09-03
IE54702B1 (en) 1990-01-17
DK160562C (da) 1991-09-02
DK84783A (da) 1983-09-06
JPH0751063B2 (ja) 1995-06-05
IE830467L (en) 1983-09-05
EP0088606B1 (en) 1987-07-29
US4432751A (en) 1984-02-21
DK84783D0 (da) 1983-02-24
JPH0537B2 (https=) 1993-01-05
DK160562B (da) 1991-03-25
JPS58192831A (ja) 1983-11-10

Similar Documents

Publication Publication Date Title
CA1209500A (en) Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction
Glaser et al. Prolieferative vitreoretinopathy: the mechanism of development of vitreoretinal traction
Yamamoto Growth of lens and ocular environment: role of neural retina in the growth of mouse lens as revealed by an implantation experiment
SAIKA et al. Immunolocalization of prolyl 4-hydroxylase subunits, α-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants
Tomokane et al. Rosenthal fibers share epitopes with alpha B-crystallin, glial fibrillary acidic protein, and ubiquitin, but not with vimentin. Immunoelectron microscopy with colloidal gold
US4996159A (en) Neovascularization inhibitors and methods for their production and use
AU602993B2 (en) Mitotic inhibitor and method for preventing posterior lens capsule opacification after extracapsular extraction
Marcantonio et al. Lens cell populations studied in human donor capsular bags with implanted intraocular lenses
Cadelli et al. Regeneration of lesioned septohippocampal acetylcholinesterase‐positive axons is improved by antibodies against the myelin‐associated neurite growth inhibitors NI‐35/250
Rungger-Brändle et al. Bilateral acute retinal necrosis (BARN): identification of the presumed infectious agent
Takata et al. Phosphotyrosine-modified proteins are concentrated at the membranes of epithelial and endothelial cells during tissue development in chick embryos.
Lange et al. Corneal endothelial cell transplantation using Descemet's membrane as a carrier
Gwon et al. A histologic study of lens regeneration in aphakic rabbits.
Hayashida et al. Transplantation of tissue-engineered epithelial cell sheets after excimer laser photoablation reduces postoperative corneal haze
Tarsio et al. Inhibition of cell proliferation on lens capsules by 4197X-ricin A immunoconjugate
Felton et al. Vitreous inhibition of tumor neovascularization
Crawford Cloned pigmented retinal epiehtlium. The role of microfilaments in the differentiation of cell shape.
Saika et al. Osteopontin: a component of matrix in capsular opacification and subcapsular cataract
EA002986B1 (ru) Применение фактора роста нервов для хранения, продуцирования и лечения роговицы и конъюнктивы
Gwon et al. Induction of de novo synthesis of crystalline lenses in aphakic rabbits
Ehrlich et al. The effects of anti-cornea and anti-heart serum on cultured cells of rabbit cornea and other tissues
Saika et al. Collagenous deposits on explanted intraocular lenses
US5202252A (en) Monoclonal antibodies against lens epithelial cells and methods for preventing proliferation of remnant lens epithelial cells after extracapsular extraction
CN113559121B (zh) 一种用于角膜移植免疫排斥反应治疗的药物
Saika et al. Pathological findings in lens capsule and silicone intraocular lens extracted from eye with chronic infectious endophthalmitis

Legal Events

Date Code Title Description
MKEX Expiry