CA1116594A - Peptides which inhibit gonadal function - Google Patents

Peptides which inhibit gonadal function

Info

Publication number
CA1116594A
CA1116594A CA000317018A CA317018A CA1116594A CA 1116594 A CA1116594 A CA 1116594A CA 000317018 A CA000317018 A CA 000317018A CA 317018 A CA317018 A CA 317018A CA 1116594 A CA1116594 A CA 1116594A
Authority
CA
Canada
Prior art keywords
trp
pro
phe
leu
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000317018A
Other languages
English (en)
French (fr)
Inventor
Catherine L. Rivier
Jean E.F. Rivier
Wylie W. Vale, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/950,301 external-priority patent/US4215038A/en
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Application granted granted Critical
Publication of CA1116594A publication Critical patent/CA1116594A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA000317018A 1977-11-30 1978-11-28 Peptides which inhibit gonadal function Expired CA1116594A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85583777A 1977-11-30 1977-11-30
US950,301 1978-10-16
US05/950,301 US4215038A (en) 1978-10-16 1978-10-16 Peptides which inhibit gonadal function
US855,837 1986-04-24

Publications (1)

Publication Number Publication Date
CA1116594A true CA1116594A (en) 1982-01-19

Family

ID=27127312

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000317018A Expired CA1116594A (en) 1977-11-30 1978-11-28 Peptides which inhibit gonadal function

Country Status (9)

Country Link
AU (1) AU520419B2 (xx)
CA (1) CA1116594A (xx)
CH (1) CH639942A5 (xx)
DE (1) DE2851630A1 (xx)
FR (1) FR2410642A1 (xx)
GB (1) GB2009182B (xx)
NL (1) NL7811723A (xx)
NZ (1) NZ188987A (xx)
SE (1) SE444946B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409208A (en) * 1980-04-15 1983-10-11 The Salk Institute For Biological Studies GnRH antagonists
US4292313A (en) * 1980-04-15 1981-09-29 The Salk Institute For Biological Studies LRF Antagonists
NZ196558A (en) * 1980-04-15 1984-10-19 Salk Inst For Biological Studi Lrf antagonists and pharmaceutical compositions
DE3165535D1 (en) * 1980-06-02 1984-09-20 Andrew Victor Schally Lh-rh antagonists
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
US4530920A (en) * 1983-11-07 1985-07-23 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
IL74827A (en) * 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
US4632979A (en) * 1984-06-18 1986-12-30 Tulane Educational Fund Therapeutic LHRH analogs
US4866160A (en) * 1985-04-09 1989-09-12 The Administrators Of The Tulane Educational Fund Therapeutic decapeptides
ZA862570B (en) * 1985-04-09 1986-12-30 Univ Tulane Therapeutic decapeptides
EP0225746A3 (en) * 1985-11-14 1989-12-20 The Administrators of The Tulane Educational Fund Therapeutic decapeptides
DE3634435A1 (de) * 1986-10-09 1988-04-14 Hoechst Ag Analoga von gonadoliberin mit verbesserter loeslichkeit, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
EP0328090A3 (en) * 1988-02-10 1990-08-16 Abbott Laboratories Lhrh analogs
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
US5084443A (en) * 1989-12-04 1992-01-28 Biomeasure, Inc. Promoting expression of acetylcholine receptors with lhrh antagonist

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928307A (en) * 1974-11-04 1975-12-23 American Home Prod P-Glu-D-Phe-Trp-Ser-Tyr-D-Phee-Leu-Arg-Pro-Gly-NH2 and intermediates
US3933782A (en) * 1974-11-14 1976-01-20 American Home Products Corporation (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates
US4089946A (en) * 1976-06-07 1978-05-16 American Home Products Corporation Claudogenic-interceptive nonapeptides

Also Published As

Publication number Publication date
GB2009182B (en) 1982-02-24
GB2009182A (en) 1979-06-13
DE2851630A1 (de) 1979-05-31
SE7812255L (sv) 1979-05-31
NZ188987A (en) 1982-02-23
CH639942A5 (de) 1983-12-15
AU520419B2 (en) 1982-01-28
FR2410642B1 (xx) 1983-10-21
FR2410642A1 (fr) 1979-06-29
AU4194878A (en) 1979-06-07
SE444946B (sv) 1986-05-20
NL7811723A (nl) 1979-06-01

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Legal Events

Date Code Title Description
MKEX Expiry