CA1102313A - Somatostatin analogs with dissociated biological activities - Google Patents

Somatostatin analogs with dissociated biological activities

Info

Publication number
CA1102313A
CA1102313A CA279,918A CA279918A CA1102313A CA 1102313 A CA1102313 A CA 1102313A CA 279918 A CA279918 A CA 279918A CA 1102313 A CA1102313 A CA 1102313A
Authority
CA
Canada
Prior art keywords
cys
ser
asn
peptide
trp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA279,918A
Other languages
English (en)
French (fr)
Inventor
Wylie W. Vale, Jr.
Jean E.F. Rivier
Marvin R. Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/785,533 external-priority patent/US4133782A/en
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Application granted granted Critical
Publication of CA1102313A publication Critical patent/CA1102313A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA279,918A 1976-06-07 1977-06-06 Somatostatin analogs with dissociated biological activities Expired CA1102313A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69328276A 1976-06-07 1976-06-07
US693,282 1976-06-07
US785,533 1977-04-07
US05/785,533 US4133782A (en) 1976-06-07 1977-04-07 Somatostatin analogs with dissociated biological activities

Publications (1)

Publication Number Publication Date
CA1102313A true CA1102313A (en) 1981-06-02

Family

ID=27105142

Family Applications (1)

Application Number Title Priority Date Filing Date
CA279,918A Expired CA1102313A (en) 1976-06-07 1977-06-06 Somatostatin analogs with dissociated biological activities

Country Status (11)

Country Link
JP (1) JPS52156885A (cs)
AU (1) AU509631B2 (cs)
CA (1) CA1102313A (cs)
CH (1) CH640827A5 (cs)
DE (1) DE2725735A1 (cs)
DK (1) DK250977A (cs)
FR (1) FR2375190A1 (cs)
GB (1) GB1567341A (cs)
IL (1) IL52231A (cs)
NL (1) NL7706002A (cs)
SE (1) SE441452B (cs)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904594A (en) * 1973-07-02 1975-09-09 Salk Inst For Biological Studi Somatostatin and acylated des-(ala' 1', gly' 2') derivatives thereof
US3842067A (en) * 1973-07-27 1974-10-15 American Home Prod Synthesis of(des-asn5)-srif and intermediates

Also Published As

Publication number Publication date
FR2375190A1 (fr) 1978-07-21
SE7706567L (sv) 1977-12-08
NL7706002A (nl) 1977-12-09
IL52231A (en) 1980-05-30
DE2725735A1 (de) 1977-12-15
AU2577577A (en) 1978-12-07
IL52231A0 (en) 1977-08-31
FR2375190B1 (cs) 1981-10-30
GB1567341A (en) 1980-05-14
JPS6315280B2 (cs) 1988-04-04
CH640827A5 (en) 1984-01-31
AU509631B2 (en) 1980-05-22
DK250977A (da) 1977-12-08
JPS52156885A (en) 1977-12-27
SE441452B (sv) 1985-10-07

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Legal Events

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