CA1056685A - Active agent dispenser and process for making same - Google Patents

Active agent dispenser and process for making same

Info

Publication number
CA1056685A
CA1056685A CA239,459A CA239459A CA1056685A CA 1056685 A CA1056685 A CA 1056685A CA 239459 A CA239459 A CA 239459A CA 1056685 A CA1056685 A CA 1056685A
Authority
CA
Canada
Prior art keywords
active agent
dispenser
lamina
drug
core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA239,459A
Other languages
English (en)
French (fr)
Inventor
Robert M. Gale
Richard W. Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of CA1056685A publication Critical patent/CA1056685A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA239,459A 1974-11-14 1975-11-12 Active agent dispenser and process for making same Expired CA1056685A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US523720A US3926188A (en) 1974-11-14 1974-11-14 Laminated drug dispenser

Publications (1)

Publication Number Publication Date
CA1056685A true CA1056685A (en) 1979-06-19

Family

ID=24086191

Family Applications (1)

Application Number Title Priority Date Filing Date
CA239,459A Expired CA1056685A (en) 1974-11-14 1975-11-12 Active agent dispenser and process for making same

Country Status (10)

Country Link
US (1) US3926188A (sv)
JP (1) JPS6059203B2 (sv)
CA (1) CA1056685A (sv)
CH (1) CH634226A5 (sv)
DE (1) DE2549856C2 (sv)
FR (1) FR2290891A1 (sv)
GB (1) GB1477813A (sv)
IT (1) IT1050619B (sv)
MX (2) MX158867A (sv)
SE (1) SE439432B (sv)

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US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
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DE3115763A1 (de) * 1981-04-18 1982-11-04 Edgar Dr.med. 6238 Hofheim Lenhard Medizinische depotsonde zur lokalen protrahierten wirkstoffreisetzung
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
JPS58134019A (ja) * 1982-02-05 1983-08-10 Ono Pharmaceut Co Ltd プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法
US4571039A (en) * 1983-04-15 1986-02-18 Stanley Poler Eye-medicating contact-lens construction
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US4564364A (en) * 1983-05-26 1986-01-14 Alza Corporation Active agent dispenser
US4601893A (en) * 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
US4863445A (en) * 1984-07-30 1989-09-05 Baxter Travenol Laboratories, Inc. Assembly for inhibiting microbial growth in collected fluid
US4693895A (en) * 1984-10-26 1987-09-15 Alza Corporation Colon delivery system
US4627851A (en) * 1984-10-26 1986-12-09 Alza Corporation Colonic-therapeutic delivery system
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US4880633A (en) * 1986-03-12 1989-11-14 Merck & Co., Inc. Transdermal drug delivery system
US4938759A (en) * 1986-09-02 1990-07-03 Alza Corporation Transdermal delivery device having a rate controlling adhesive
US4908027A (en) * 1986-09-12 1990-03-13 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
US5344656A (en) * 1986-09-12 1994-09-06 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
US4841968A (en) * 1986-09-26 1989-06-27 Southern Research Institute Antithrombotic/thrombolytic suture and methods of making and using the same
US4830860A (en) * 1986-10-30 1989-05-16 Pfizer Inc. Stressed polymeric device for controlled release of a substance to an ambient environment
JPS63143581A (ja) * 1986-12-05 1988-06-15 Nissha Printing Co Ltd ホログラム成型品
US4892778A (en) * 1987-05-27 1990-01-09 Alza Corporation Juxtaposed laminated arrangement
DE19975054I2 (de) * 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
DK530787D0 (da) * 1987-10-09 1987-10-09 Bukh Meditec Indretning til indfoering i en legemshulhed
US4959208A (en) * 1987-10-19 1990-09-25 Ppg Industries, Inc. Active agent delivery device
US5035886A (en) * 1987-10-19 1991-07-30 Ppg Industries, Inc. Active agent delivery device
US5071645A (en) * 1987-10-19 1991-12-10 Ppg Industries, Inc. Process of producing an active agent delivery device
US4781924A (en) 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
US5004610A (en) * 1988-06-14 1991-04-02 Alza Corporation Subsaturated nicotine transdermal therapeutic system
GB8815968D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Veterinary devices
US5053227A (en) * 1989-03-22 1991-10-01 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US5059426A (en) * 1989-03-22 1991-10-22 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US4973468A (en) * 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5508038A (en) * 1990-04-16 1996-04-16 Alza Corporation Polyisobutylene adhesives for transdermal devices
AU660290B2 (en) * 1990-08-09 1995-06-22 Endocon, Inc. Multiple drug delivery system
JPH0444601U (sv) * 1990-08-22 1992-04-15
JPH0444666U (sv) * 1990-08-22 1992-04-15
US5538735A (en) * 1993-02-19 1996-07-23 Ahn; Sam S. Method of making a drug delivery system using hollow fibers
JP3720386B2 (ja) * 1993-12-27 2005-11-24 住友製薬株式会社 薬物放出制御製剤
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
AU6061201A (en) * 2000-05-26 2001-12-03 Kanji Takada Nonoral preparation having three-layer structure
US20020148138A1 (en) * 2001-04-06 2002-10-17 Egan Brian A. Smart tread boot covers
WO2002100318A2 (en) 2001-06-12 2002-12-19 Johns Hopkins University School Of Medicine Reservoir device for intraocular drug delivery
US7306580B2 (en) * 2003-04-16 2007-12-11 Cook Incorporated Medical device with therapeutic agents
CA2531640C (en) * 2003-07-10 2013-06-18 Galen (Chemicals) Limited Intravaginal drug delivery devices
CN1882338A (zh) * 2003-09-18 2006-12-20 马库赛特公司 经巩膜递送
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
DE102004050457A1 (de) * 2004-10-12 2006-04-13 Capsulution Nanoscience Ag Segmentierte Vorrichtung für die verzögerte Freisetzung von Molekülen in tangentialer Richtung durch dünne Filme und Anwendungen derselben
US8663639B2 (en) 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
US20060258698A1 (en) 2005-02-09 2006-11-16 Sreenivasu Mudumba Liquid formulations for treatment of diseases or conditions
US8492400B2 (en) 2006-02-09 2013-07-23 Santen Pharmaceutical Co., Ltd. Stable formulations, and methods of their preparation and use
JP5506378B2 (ja) 2006-03-23 2014-05-28 参天製薬株式会社 血管透過性に関連する疾患または病気のための製剤および方法
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
US8399006B2 (en) 2009-01-29 2013-03-19 Forsight Vision4, Inc. Posterior segment drug delivery
ES2921527T3 (es) 2009-06-03 2022-08-29 Forsight Vision5 Inc Administración de fármaco en segmento anterior
US20110066141A1 (en) * 2009-09-11 2011-03-17 Cook Incorporated Implantable medical device having an anti-gastric distress agent
US20110098797A1 (en) * 2009-10-23 2011-04-28 Cleek Robert L Drug eluting composite
US9320890B2 (en) * 2009-11-09 2016-04-26 W. L. Gore & Associates, Inc. Drug eluting composite
US9504771B2 (en) 2009-11-09 2016-11-29 W. L. Gore & Associates, Inc. Drug eluting composite
ES2699200T3 (es) 2010-03-16 2019-02-07 Titan Pharmaceuticals Inc Dispositivos implantables heterogéneos de administración de fármacos
US9033911B2 (en) 2010-08-05 2015-05-19 Forsight Vision4, Inc. Injector apparatus and method for drug delivery
US9492315B2 (en) 2010-08-05 2016-11-15 Forsight Vision4, Inc. Implantable therapeutic device
JP6111194B2 (ja) 2010-08-05 2017-04-05 フォーサイト・ビジョン フォー・インコーポレーテッド 組み合わせ薬物送達方法および装置
US20140031769A1 (en) 2010-11-19 2014-01-30 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
US10398592B2 (en) 2011-06-28 2019-09-03 Forsight Vision4, Inc. Diagnostic methods and apparatus
EP2739252A4 (en) 2011-08-05 2015-08-12 Forsight Vision4 Inc SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE
RU2740680C2 (ru) 2011-09-14 2021-01-19 Форсайт Вижн5, Инк. Глазное вкладочное устройство и способы
PT2755600T (pt) 2011-09-16 2021-04-19 Forsight Vision4 Inc Aparelhos de troca de fluidos
WO2013056213A1 (en) * 2011-10-14 2013-04-18 Purdue Research Foundation Ingestible multi-sheet unit having predetermined functions and combinations
CN104884006B (zh) 2012-10-26 2017-12-15 弗赛特影像5股份有限公司 用于持续释放药物到眼睛的眼科系统
EP2968113B8 (en) 2013-03-14 2020-10-28 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
ES2972168T3 (es) 2013-03-28 2024-06-11 Forsight Vision4 Inc Implante oftálmico para administración de sustancias terapéuticas
MY182793A (en) 2014-08-08 2021-02-05 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
US10226419B2 (en) * 2014-09-08 2019-03-12 ProMed Pharma, LLC Methods for manufacturing implants
CA2967330A1 (en) 2014-11-10 2016-05-19 Forsight Vision4, Inc. Expandable drug delivery devices and methods of use
WO2016168141A1 (en) 2015-04-13 2016-10-20 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
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US2928770A (en) * 1958-11-28 1960-03-15 Frank M Bardani Sustained action pill
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US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3630200A (en) * 1969-06-09 1971-12-28 Alza Corp Ocular insert
US3618604A (en) * 1969-06-09 1971-11-09 Alza Corp Ocular insert
US3625214A (en) * 1970-05-18 1971-12-07 Alza Corp Drug-delivery device
US3832252A (en) * 1970-09-29 1974-08-27 T Higuchi Method of making a drug-delivery device
US3797485A (en) * 1971-03-26 1974-03-19 Alza Corp Novel drug delivery device for administering drug into blood circulation in blood vessel
US3851648A (en) * 1973-10-11 1974-12-03 Mead Johnson & Co Zero-order release device

Also Published As

Publication number Publication date
DE2549856C2 (de) 1985-01-03
IT1050619B (it) 1981-03-20
SE7512744L (sv) 1977-05-15
US3926188A (en) 1975-12-16
FR2290891B1 (sv) 1978-11-10
JPS5170807A (sv) 1976-06-18
MX158867A (es) 1989-03-27
JPS6059203B2 (ja) 1985-12-24
CH634226A5 (de) 1983-01-31
GB1477813A (en) 1977-06-29
DE2549856A1 (de) 1976-05-20
FR2290891A1 (fr) 1976-06-11
SE439432B (sv) 1985-06-17
MX158868A (es) 1989-03-27

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