CA1036598A - Piperazino-pyrimidines utilisables comme medicaments - Google Patents

Piperazino-pyrimidines utilisables comme medicaments

Info

Publication number
CA1036598A
CA1036598A CA233,149A CA233149A CA1036598A CA 1036598 A CA1036598 A CA 1036598A CA 233149 A CA233149 A CA 233149A CA 1036598 A CA1036598 A CA 1036598A
Authority
CA
Canada
Prior art keywords
group
carbon atoms
compounds
alkyl group
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA233,149A
Other languages
English (en)
French (fr)
Inventor
Gerard Loiseau
Georges Mattioda
Rene Millischer
Pierre Obellianne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Produits Chimiques Ugine Kuhlmann
Original Assignee
Produits Chimiques Ugine Kuhlmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Produits Chimiques Ugine Kuhlmann filed Critical Produits Chimiques Ugine Kuhlmann
Application granted granted Critical
Publication of CA1036598A publication Critical patent/CA1036598A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA233,149A 1974-08-09 1975-08-08 Piperazino-pyrimidines utilisables comme medicaments Expired CA1036598A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7427671A FR2281117A2 (fr) 1974-08-09 1974-08-09 Nouvelles piperazino-pyrimidines utilisables comme medicaments

Publications (1)

Publication Number Publication Date
CA1036598A true CA1036598A (fr) 1978-08-15

Family

ID=9142279

Family Applications (1)

Application Number Title Priority Date Filing Date
CA233,149A Expired CA1036598A (fr) 1974-08-09 1975-08-08 Piperazino-pyrimidines utilisables comme medicaments

Country Status (13)

Country Link
JP (2) JPS51125089A (enrdf_load_stackoverflow)
AR (1) AR205579A1 (enrdf_load_stackoverflow)
BE (1) BE832277R (enrdf_load_stackoverflow)
CA (1) CA1036598A (enrdf_load_stackoverflow)
CH (1) CH609692A5 (enrdf_load_stackoverflow)
DE (1) DE2534963A1 (enrdf_load_stackoverflow)
ES (1) ES440153A2 (enrdf_load_stackoverflow)
FR (1) FR2281117A2 (enrdf_load_stackoverflow)
GB (1) GB1512101A (enrdf_load_stackoverflow)
LU (1) LU73175A1 (enrdf_load_stackoverflow)
NL (1) NL7509184A (enrdf_load_stackoverflow)
NO (1) NO752586L (enrdf_load_stackoverflow)
ZA (1) ZA755118B (enrdf_load_stackoverflow)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2417507A2 (fr) * 1977-07-28 1979-09-14 Ugine Kuhlmann Diamino-2,4 (ou -4,6) methylthio-5 pyrimidines herbicides
FR2503162A1 (fr) * 1981-04-07 1982-10-08 Pharmindustrie Nouveaux derives de piperazino-2 pyrimidine, procedes pour leur preparation et leur utilisation comme medicaments ou comme intermediaires pour la fabrication de medicaments
JPS5973573A (ja) * 1982-09-09 1984-04-25 ワ−ナ−−ランバ−ト・コンパニ− ジアミノピリミジン化合物
US6825198B2 (en) 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
JP2007521287A (ja) 2003-07-02 2007-08-02 バーテックス　ファーマシューティカルズ　インコーポレイテッド 電位依存性イオンチャネルの調節因子として有用なピリミジン
EP1904491A2 (en) 2005-05-31 2008-04-02 Vertex Pharmaceuticals Incorporated Heterocycles useful as modulators of ion channels

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2119234A5 (en) * 1970-12-24 1972-08-04 Ugine Kuhlmann 5-alkylthio amino halopyrimidines - fungicides herbicides insecticides and bactericides
FR2173746B1 (enrdf_load_stackoverflow) * 1972-03-01 1975-04-25 Ugine Kuhlmann

Also Published As

Publication number Publication date
NO752586L (enrdf_load_stackoverflow) 1976-02-10
AR205579A1 (es) 1976-05-14
FR2281117A2 (fr) 1976-03-05
GB1512101A (en) 1978-05-24
NL7509184A (nl) 1976-02-11
ZA755118B (en) 1976-07-28
JPS58150571A (ja) 1983-09-07
LU73175A1 (enrdf_load_stackoverflow) 1976-03-02
BE832277R (fr) 1976-02-09
DE2534963A1 (de) 1976-02-19
ES440153A2 (es) 1977-07-01
CH609692A5 (en) 1979-03-15
JPS51125089A (en) 1976-11-01
FR2281117B2 (enrdf_load_stackoverflow) 1978-07-28
JPS5946943B2 (ja) 1984-11-15

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