BRPI0501708A - transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device - Google Patents
transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal deviceInfo
- Publication number
- BRPI0501708A BRPI0501708A BRPI0501708A BRPI0501708A BR PI0501708 A BRPI0501708 A BR PI0501708A BR PI0501708 A BRPI0501708 A BR PI0501708A BR PI0501708 A BRPI0501708 A BR PI0501708A
- Authority
- BR
- Brazil
- Prior art keywords
- transdermal
- slow
- producing
- release device
- excess
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
Abstract
DIPOSITIVO DE LIBERAçãO LENTA POR PROCESSO TRANSDéRMICO DE UM MEDICAMENTO CONTRA O EXECESSO DE COLESTEROL E MéTODO DE PRODUçãO DE UM DISPOSITIVO TRANSDéRMICO,o qual é caracterizado por prever um dispositivo bi-laminar,leberação lenta transdérmica constituída de uma matriz macromolecular flexível (2) de uma espessura de 0,15 0, 6 cm e de uma superfície entre 10 e 100 cm quadrados e apresentando de um lado um revestimento posterior (1), permitindo uma redução considerável (mais de 15 vezes) das doses diárias a serem asministradas no tratamento do excesso de colesterol,a matriz macromolecular contendo e liberando de maneira contínua durante um período de 1 a 4 meses 0, 05 a 18% por dias de seu peso total em ómega 3 e/ou estatina,pela superfície em contato com a pele do paciente sem precisar aderir de forma fixa e permanente à pele do mesmo.SLOW RELEASE DEVICE BY TRANSDERMAL PROCESS OF A MEDICINAL PRODUCT AGAINST EXCESS OF CHOLESTEROL AND PRODUCTION METHOD OF A TRANSDERMAL DEVICE, which is characterized by providing a bi-laminar device, slow transdermal leberation consisting of a flexible macromolecular matrix (2) thickness of 0.15 0.6 cm and a surface area of 10 to 100 cm square and having on one side a backing (1), allowing a considerable reduction (more than 15 times) of the daily doses to be administered in the treatment of excess cholesterol, the macromolecular matrix containing and releasing continuously over a period of 1 to 4 months 0, 05 to 18% per day of its total weight in omega 3 and / or statin, by the surface in contact with the patient's skin without sticking permanently to the skin of the same.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0501708 BRPI0501708A (en) | 2005-05-10 | 2005-05-10 | transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device |
PCT/BR2006/000090 WO2006119598A2 (en) | 2005-05-10 | 2006-05-10 | Transdermal device for the slow delivery of an omega-3-fatty acid, optionally in combination with a hmg coa reductase inhibitor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0501708 BRPI0501708A (en) | 2005-05-10 | 2005-05-10 | transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0501708A true BRPI0501708A (en) | 2007-05-02 |
Family
ID=37396906
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0501708 BRPI0501708A (en) | 2005-05-10 | 2005-05-10 | transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device |
Country Status (2)
Country | Link |
---|---|
BR (1) | BRPI0501708A (en) |
WO (1) | WO2006119598A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2940116B1 (en) * | 2008-12-22 | 2012-07-06 | Philippe Perovitch | FORMULATION FOR THE ADMINISTRATION OF HYPOLIPEMIC BY ORAL TRANS-MUCOSAL |
US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
WO2012170417A2 (en) | 2011-06-06 | 2012-12-13 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2548021B1 (en) * | 1983-06-29 | 1986-02-28 | Dick P R | PROLONGED AND CONTINUOUS DERMAL PHARMACEUTICAL COMPOSITIONS BASED ON ESSENTIAL FATTY ACIDS |
JP4062639B2 (en) * | 1996-12-23 | 2008-03-19 | 日本水産株式会社 | Skin preparation |
DE10056010A1 (en) * | 2000-11-11 | 2002-05-16 | Beiersdorf Ag | Well tolerated plaster for controlled delivery of cosmetic skin care agents, having active agent-containing matrix comprising polyisobutylene, amorphous poly-alpha-olefin and optionally filler |
-
2005
- 2005-05-10 BR BRPI0501708 patent/BRPI0501708A/en not_active Application Discontinuation
-
2006
- 2006-05-10 WO PCT/BR2006/000090 patent/WO2006119598A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2006119598A3 (en) | 2007-03-01 |
WO2006119598A2 (en) | 2006-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |