BR9809478A - Uso de um oligossacarìdeo sintético, processos para prevenção de coagulação sanguìnea em um mamìfero e para prevenção de coagulação sanguìnea e um circuito sanguìneo extracorpóreo, e, composição farmacêutica adaptada para prevenir coagulação sanguìnea em um circuito sanguìneo extracorpóreo - Google Patents
Uso de um oligossacarìdeo sintético, processos para prevenção de coagulação sanguìnea em um mamìfero e para prevenção de coagulação sanguìnea e um circuito sanguìneo extracorpóreo, e, composição farmacêutica adaptada para prevenir coagulação sanguìnea em um circuito sanguìneo extracorpóreoInfo
- Publication number
- BR9809478A BR9809478A BR9809478-5A BR9809478A BR9809478A BR 9809478 A BR9809478 A BR 9809478A BR 9809478 A BR9809478 A BR 9809478A BR 9809478 A BR9809478 A BR 9809478A
- Authority
- BR
- Brazil
- Prior art keywords
- blood clotting
- preventing
- clotting
- extracorporeal
- circuit
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Materials For Medical Uses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
"USO DE UM OLIGOSSACARìDEO SINTéTICO, PROCESSOS PARA PREVENçãO DE COAGULAçãO SANGUìNEA EM UM MAMìFERO E PARA PREVENçãO DE COAGULAçãO SANGUìNEA EM UM CIRCUITO SANGUìNEO EXTRACORPóREO, E, COMPOSIçãO FARMACêUTICA ADAPTADA PARA PREVENIR COAGULAçãO SANGUìNEA EM UM CIRCUITO SANGUìNEO EXTRACORPóREO". A invenção refere-se ao uso de um oligossacarídeo sintético que é inibidor seletivo de fator Xa, atuando via antitrombina III, para a produção de um medicamento para prevenção de coágulo sanguíneo em pacientes com um circuito sanguíneo extracorpóreo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97201586 | 1997-05-27 | ||
PCT/EP1998/003174 WO1998053829A1 (en) | 1997-05-27 | 1998-05-22 | Use of oligosaccharide for preventing blood clotting in extracorporeal blood circuits |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9809478A true BR9809478A (pt) | 2000-06-20 |
Family
ID=8228366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9809478-5A BR9809478A (pt) | 1997-05-27 | 1998-05-22 | Uso de um oligossacarìdeo sintético, processos para prevenção de coagulação sanguìnea em um mamìfero e para prevenção de coagulação sanguìnea e um circuito sanguìneo extracorpóreo, e, composição farmacêutica adaptada para prevenir coagulação sanguìnea em um circuito sanguìneo extracorpóreo |
Country Status (12)
Country | Link |
---|---|
US (3) | US6391339B1 (pt) |
EP (2) | EP0984785B1 (pt) |
JP (2) | JP2002503270A (pt) |
AT (1) | ATE307596T1 (pt) |
AU (1) | AU8211398A (pt) |
BR (1) | BR9809478A (pt) |
CA (1) | CA2289522A1 (pt) |
DE (1) | DE69832066T2 (pt) |
DK (1) | DK0984785T3 (pt) |
ES (1) | ES2251090T3 (pt) |
NO (1) | NO325142B1 (pt) |
WO (1) | WO1998053829A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2289522A1 (en) * | 1997-05-27 | 1998-12-03 | Akzo Nobel Nv | Use of oligosaccharide for preventing blood clotting in extracorporeal blood circuits |
FR2804328B1 (fr) | 2000-01-27 | 2002-03-15 | Hospal Ind | Membrane semi-permeable non thrombogene et procede de fabrication |
JP2006096668A (ja) * | 2002-11-08 | 2006-04-13 | Ono Pharmaceut Co Ltd | エラスターゼ阻害剤と血液凝固系および/または線溶系酵素阻害剤との組み合わせからなる医薬 |
JP5925693B2 (ja) * | 2009-12-01 | 2016-05-25 | エクステラ・メディカル・コーポレーション | 表面固定した多糖類を用いた、血液からのサイトカイン除去法 |
WO2013188073A1 (en) | 2012-06-13 | 2013-12-19 | Exthera Medical, Llc | Use of heparin and carbohydrates to treat cancer |
CA2928866C (en) | 2013-11-08 | 2021-11-09 | Exthera Medical Corporation | Methods for diagnosing infectious diseases using adsorption media |
JP2017513636A (ja) | 2014-04-24 | 2017-06-01 | エクスセラ メディカル コーポレイション | 高流量を用いて血液から細菌を除去するための方法 |
US11911551B2 (en) | 2016-03-02 | 2024-02-27 | Exthera Medical Corporation | Method for treating drug intoxication |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2002A (en) * | 1841-03-12 | Tor and planter for plowing | ||
DE3008993A1 (de) * | 1980-03-08 | 1981-10-01 | Röhm Pharma GmbH, 6100 Darmstadt | Pharmazeutische zubereitungen |
US4331697A (en) * | 1980-09-02 | 1982-05-25 | Teijin Limited | Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative |
US4818816A (en) * | 1981-04-28 | 1989-04-04 | Choay, S.A. | Process for the organic synthesis of oligosaccharides and derivatives thereof |
US4987223A (en) * | 1981-12-23 | 1991-01-22 | Choay S.A. | Derivatives of the uronic acid |
AU563351C (en) * | 1982-01-15 | 2003-06-19 | Glaxo Group Limited | Synthesis of oligosaccharides |
US4801583A (en) * | 1982-01-15 | 1989-01-31 | Choay S.A. | Oligosaccharides and their biological applications |
JPS63218691A (ja) * | 1987-03-09 | 1988-09-12 | Rikagaku Kenkyusho | 新規な5糖類化合物及びその製造法並びに抗凝血及び抗血栓剤 |
EP0300099A1 (en) * | 1987-07-20 | 1989-01-25 | Akzo N.V. | New pentasaccharides |
US5256559A (en) * | 1988-03-04 | 1993-10-26 | Biogen, Inc. | Methods and compositions for inhibiting platelet aggregation |
US5252213A (en) * | 1989-06-20 | 1993-10-12 | University Of Washington | Dry dialysate composition |
US5378829A (en) * | 1990-04-23 | 1995-01-03 | Akzo N.V. | Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type |
WO1993005825A1 (en) * | 1991-09-20 | 1993-04-01 | Baxter International Inc. | Processes for reducing the thrombogenicity of biomaterials |
ITPD940054A1 (it) * | 1994-03-23 | 1995-09-23 | Fidia Advanced Biopolymers Srl | Polisaccaridi solfatati |
US6391369B1 (en) * | 1996-03-27 | 2002-05-21 | Bunge Foods Corporation | Selectively hydrogenated high oleic oil compositions and process |
IL120722A (en) * | 1996-05-08 | 1999-07-14 | Akzo Nobel Nv | Polysulfated tetrasaccharide derivatives and pharmaceutical compositions containing them |
CA2289522A1 (en) * | 1997-05-27 | 1998-12-03 | Akzo Nobel Nv | Use of oligosaccharide for preventing blood clotting in extracorporeal blood circuits |
-
1998
- 1998-05-22 CA CA002289522A patent/CA2289522A1/en not_active Abandoned
- 1998-05-22 DE DE69832066T patent/DE69832066T2/de not_active Expired - Lifetime
- 1998-05-22 WO PCT/EP1998/003174 patent/WO1998053829A1/en active IP Right Grant
- 1998-05-22 DK DK98932096T patent/DK0984785T3/da active
- 1998-05-22 AT AT98932096T patent/ATE307596T1/de active
- 1998-05-22 EP EP98932096A patent/EP0984785B1/en not_active Expired - Lifetime
- 1998-05-22 JP JP50025099A patent/JP2002503270A/ja active Pending
- 1998-05-22 BR BR9809478-5A patent/BR9809478A/pt not_active Application Discontinuation
- 1998-05-22 US US09/424,626 patent/US6391339B1/en not_active Expired - Lifetime
- 1998-05-22 AU AU82113/98A patent/AU8211398A/en not_active Abandoned
- 1998-05-22 ES ES98932096T patent/ES2251090T3/es not_active Expired - Lifetime
- 1998-05-22 EP EP05015221A patent/EP1593380A3/en not_active Withdrawn
-
1999
- 1999-11-26 NO NO19995800A patent/NO325142B1/no not_active IP Right Cessation
-
2001
- 2001-11-02 US US10/005,793 patent/US20020040012A1/en not_active Abandoned
-
2006
- 2006-08-14 US US11/464,259 patent/US20070197637A1/en not_active Abandoned
-
2009
- 2009-08-25 JP JP2009193834A patent/JP2010013455A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69832066D1 (de) | 2005-12-01 |
US20070197637A1 (en) | 2007-08-23 |
NO325142B1 (no) | 2008-02-11 |
NO995800L (no) | 1999-11-26 |
US6391339B1 (en) | 2002-05-21 |
CA2289522A1 (en) | 1998-12-03 |
JP2010013455A (ja) | 2010-01-21 |
EP0984785A1 (en) | 2000-03-15 |
ES2251090T3 (es) | 2006-04-16 |
DE69832066T2 (de) | 2006-07-13 |
ATE307596T1 (de) | 2005-11-15 |
WO1998053829A1 (en) | 1998-12-03 |
AU8211398A (en) | 1998-12-30 |
NO995800D0 (no) | 1999-11-26 |
EP1593380A3 (en) | 2008-06-11 |
EP1593380A2 (en) | 2005-11-09 |
JP2002503270A (ja) | 2002-01-29 |
DK0984785T3 (da) | 2006-01-30 |
EP0984785B1 (en) | 2005-10-26 |
US20020040012A1 (en) | 2002-04-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Free format text: SANOFI-SYNTHELABO (FR) |
|
B25D | Requested change of name of applicant approved |
Owner name: SANOFI-AVENTIS (FR) Free format text: ALTERADO DE: SANOFI-SYNTHELABO |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO REQUISEITO DE ATIVIDADE INVENTIVA ( ATIGO 8O COMBINADO COM ARTIGO 13 DA LEI 9279/96 |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] |