BR9711062A - Tienopirimidinas - Google Patents

Tienopirimidinas

Info

Publication number
BR9711062A
BR9711062A BR9711062A BR9711062A BR9711062A BR 9711062 A BR9711062 A BR 9711062A BR 9711062 A BR9711062 A BR 9711062A BR 9711062 A BR9711062 A BR 9711062A BR 9711062 A BR9711062 A BR 9711062A
Authority
BR
Brazil
Prior art keywords
tienopirimidinas
Prior art date
Application number
BR9711062A
Other languages
Portuguese (pt)
Inventor
Jonas Rochus
Pierre Schelling
Franz-Werner Kluxen
Maria Christadler
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE1996132423 priority Critical patent/DE19632423A1/en
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Priority to PCT/EP1997/004139 priority patent/WO1998006722A1/en
Publication of BR9711062A publication Critical patent/BR9711062A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
BR9711062A 1996-08-12 1997-07-30 Tienopirimidinas BR9711062A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE1996132423 DE19632423A1 (en) 1996-08-12 1996-08-12 thienopyrimidines
PCT/EP1997/004139 WO1998006722A1 (en) 1996-08-12 1997-07-30 Thienopyrimidines

Publications (1)

Publication Number Publication Date
BR9711062A true BR9711062A (en) 1999-08-17

Family

ID=7802392

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711062A BR9711062A (en) 1996-08-12 1997-07-30 Tienopirimidinas

Country Status (28)

Country Link
US (1) US6110920A (en)
EP (1) EP0920431B1 (en)
JP (1) JP4405593B2 (en)
KR (1) KR100502271B1 (en)
CN (1) CN1081638C (en)
AR (1) AR009052A1 (en)
AT (1) AT233265T (en)
AU (1) AU725227B2 (en)
BR (1) BR9711062A (en)
CA (1) CA2263561C (en)
CZ (1) CZ287772B6 (en)
DE (2) DE19632423A1 (en)
DK (1) DK0920431T3 (en)
ES (1) ES2191192T3 (en)
HK (1) HK1021731A1 (en)
HU (1) HU0001607A3 (en)
IL (1) IL128504A (en)
NO (1) NO990643L (en)
NZ (1) NZ334600A (en)
PL (1) PL190174B1 (en)
PT (1) PT920431E (en)
RU (1) RU2199541C2 (en)
SI (1) SI0920431T1 (en)
SK (1) SK282823B6 (en)
TR (1) TR199900308T2 (en)
TW (1) TW359672B (en)
WO (1) WO1998006722A1 (en)
ZA (1) ZA9707156B (en)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19819023A1 (en) * 1998-04-29 1999-11-04 Merck Patent Gmbh thienopyrimidines
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
CA2365578A1 (en) 1999-03-30 2000-10-12 Seiichi Uchida Thienopyrimidine compounds and salts thereof and process for the preparation of the same
DE10031585A1 (en) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-aminoalkyl-thieno [2,3-d] pyrimidine
JPWO2002026745A1 (en) * 2000-09-29 2004-02-05 日本曹達株式会社 Thieno pyrimidine compound and a salt thereof and manufacturing method
WO2002062343A2 (en) * 2001-02-02 2002-08-15 Merck Patent Gmbh PHARMACEUTICAL FORMULATION COMPRISING PYRAZOLO[4,3-d]PYRIMIDINES AND ENDOTHELIN RECEPTOR ANTAGONISTS OR THIENOPYRIMIDINES AND ENDOTHELIN RECEPTOR ANTAGONISTS
US6610887B2 (en) 2001-04-13 2003-08-26 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
CN100343258C (en) * 2001-04-30 2007-10-17 美国拜尔公司 Novel 4-amino-5,6-substituted thiopheno 2,3-d]pyrimidines
JPWO2003035653A1 (en) * 2001-10-26 2005-02-10 日本曹達株式会社 Pyrido thienopyrimidine compounds and their salts
US7153412B2 (en) 2001-12-28 2006-12-26 Kabushiki Kaisha Toyota Chuo Kenkyusho Electrodes, electrochemical elements, gas sensors, and gas measurement methods
US7208516B2 (en) 2002-03-20 2007-04-24 Celgene Corporation Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7276529B2 (en) 2002-03-20 2007-10-02 Celgene Corporation Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
AR044743A1 (en) * 2002-09-26 2005-10-05 Nihon Nohyaku Co Ltd Herbicidal method of using it, substituted thienopyrimidine derivatives, intermediate compounds and processes used to produce them,
GB0320300D0 (en) * 2003-08-29 2003-10-01 Cancer Rec Tech Ltd Pyrimidothiophene compounds
DE10351436A1 (en) * 2003-11-04 2005-06-09 Merck Patent Gmbh Use of thienopyrimidines
GB0420719D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
GB0420722D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
AR059898A1 (en) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivatives 3-cyano-pyridone and 1,4-disubstituted use as allosteric mGluR2 receptor modulators
TW200845978A (en) * 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) * 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
CA2697399C (en) 2007-09-14 2016-01-19 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
MX2010002536A (en) * 2007-09-14 2010-08-10 Ortho Mcneil Janssen Pharm 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h, 1'h-[1, 4'] bipyridinyl-2'-ones.
BRPI0816970A2 (en) * 2007-09-14 2015-03-24 Ortho Mcneil Janssen Pharm 1,3-disubstituted-4-phenyl-1h-pyridin-2-ones
CN101861316B (en) * 2007-11-14 2013-08-21 奥梅-杨森制药有限公司 Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors
US20100227853A1 (en) * 2008-04-18 2010-09-09 Trustees Of Boston College Inhibitors of cyclic amp phosphodiesterases
KR101523126B1 (en) 2008-07-31 2015-05-26 세노믹스, 인코포레이티드 Processes and intermediates for making sweet taste enhancers
CN102143955B (en) 2008-09-02 2013-08-14 Omj制药公司 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
ES2466341T3 (en) 2008-10-16 2014-06-10 Janssen Pharmaceuticals, Inc. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
BRPI0921333A2 (en) 2008-11-28 2015-12-29 Addex Pharmaceuticals Sa indole and benzoxazine derivatives as metabotropic glutamate receptor modulators
EP2430031B1 (en) 2009-05-12 2013-04-17 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
KR101753826B1 (en) 2009-05-12 2017-07-04 얀센 파마슈티칼즈, 인코포레이티드 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders
CA2815002C (en) 2010-11-08 2019-10-22 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
JP5852665B2 (en) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド 1,2,4-Triazolo [4,3-a] pyridine derivatives and their use as positive allosteric modulators of the mGluR2 receptor
ES2552455T3 (en) 2010-11-08 2015-11-30 Janssen Pharmaceuticals, Inc. 1,2,4-Triazolo [4,3-a] pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
EP2734530A1 (en) 2011-07-19 2014-05-28 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
CN104603132A (en) 2012-08-06 2015-05-06 赛诺米克斯公司 Sweet flavor modifier
JO3155B1 (en) 2013-02-19 2017-09-20 Senomyx Inc Sweet flavor modifier
JO3368B1 (en) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv 6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
JO3367B1 (en) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv 1,2,4-TRIAZOLO[4,3-a]PYRIDINE COMPOUNDS AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
MX2016014384A (en) 2014-06-23 2017-01-20 Celgene Corp Apremilast for the treatment of a liver disease or a liver function abnormality.
WO2018237084A1 (en) * 2017-06-21 2018-12-27 SHY Therapeutics LLC Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
ZA7802648B (en) * 1977-05-23 1979-06-27 Ici Australia Ltd The prevention,control or eradication of infestations of ixodid ticks
JP2657760B2 (en) * 1992-07-15 1997-09-24 小野薬品工業株式会社 4- aminoquinazoline derivatives and medicaments containing them
US5869486A (en) * 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds

Also Published As

Publication number Publication date
ES2191192T3 (en) 2003-09-01
NO990643D0 (en) 1999-02-11
CN1227560A (en) 1999-09-01
DK0920431T3 (en) 2003-06-02
RU2199541C2 (en) 2003-02-27
HU0001607A3 (en) 2002-09-30
HU0001607A2 (en) 2000-10-28
IL128504A (en) 2003-01-12
AR009052A1 (en) 2000-03-08
CA2263561A1 (en) 1998-02-19
DE59709404D1 (en) 2003-04-03
SI0920431T1 (en) 2003-08-31
NZ334600A (en) 2000-07-28
PL331538A1 (en) 1999-07-19
HK1021731A1 (en) 2002-12-13
AU725227B2 (en) 2000-10-12
CA2263561C (en) 2007-02-20
IL128504D0 (en) 2000-01-31
KR20000029932A (en) 2000-05-25
ZA9707156B (en) 1998-02-19
DE19632423A1 (en) 1998-02-19
JP2000516223A (en) 2000-12-05
NO990643L (en) 1999-02-11
TR199900308T2 (en) 1999-04-21
SK16499A3 (en) 1999-06-11
SK282823B6 (en) 2002-12-03
TW359672B (en) 1999-06-01
EP0920431A1 (en) 1999-06-09
EP0920431B1 (en) 2003-02-26
CN1081638C (en) 2002-03-27
KR100502271B1 (en) 2005-07-22
WO1998006722A1 (en) 1998-02-19
PL190174B1 (en) 2005-11-30
PT920431E (en) 2003-07-31
CZ287772B6 (en) 2001-01-17
CZ44899A3 (en) 1999-05-12
US6110920A (en) 2000-08-29
JP4405593B2 (en) 2010-01-27
AU4203597A (en) 1998-03-06
AT233265T (en) 2003-03-15

Similar Documents

Publication Publication Date Title
IT1296467B1 (en) Idrossifeniltriazine
BR9707598A (en) Syringe
BR9711853A (en) vaccines
BR9707523A (en) article
BR9709174A (en) Inhaler
BR9710365A (en) Device anastomÄtica conexÆo
BR9707233A (en) Phenanthridines
BR9710677A (en) Com-AEO detergent
BR9707160A (en) halopyrimidines
IT1295009B1 (en) Idrossifeniltriazine
BR9708314A (en) Pesticide
BR9711781A (en) bushing
BR9710426A (en) dirÚrgico instrument
BR9711597A (en) àculos asf-rich plans
BR9701169A (en) Polixaésteres absorbable
BR9710521A (en) Bottle
BR9609301A (en) Cetoenois di-halogenophenyl-substituted
BR9609888A (en) Halogenobenzimidazóis
BR9711799A (en) Compound indenonaftopiranos and article-malic fotocr
BR9708011A (en) Compound tríarila
BR9710678A (en) Com-AEO detergent
BR9709489A (en) Device eletromagnétiso
BR9608046A (en) Sensor
BR9608367A (en) new pre-dyes
BR9709230A (en) Compound

Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 10A ANUIDADE.

B08K Maintenance of archiving: application remains archived as no request for restauration (art. 87) has been received.

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1917 DE 02/10/2007.