BR112022010520A2 - Processo para síntese de uma 2-tioalquil pirimidina - Google Patents

Processo para síntese de uma 2-tioalquil pirimidina

Info

Publication number
BR112022010520A2
BR112022010520A2 BR112022010520A BR112022010520A BR112022010520A2 BR 112022010520 A2 BR112022010520 A2 BR 112022010520A2 BR 112022010520 A BR112022010520 A BR 112022010520A BR 112022010520 A BR112022010520 A BR 112022010520A BR 112022010520 A2 BR112022010520 A2 BR 112022010520A2
Authority
BR
Brazil
Prior art keywords
formula
compound
synthesis
thioalkyl
pyrimidine
Prior art date
Application number
BR112022010520A
Other languages
English (en)
Inventor
Hong Junbae
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of BR112022010520A2 publication Critical patent/BR112022010520A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCESSO PARA SÍNTESE DE UMA 2-TIOALQUIL PIRIMIDINA. A presente invenção refere-se a um método para preparar um composto de Fórmula 1 e compostos a partir do mesmo, que compreende tratar um composto de Fórmula 2 com um composto de Fórmula 3 e reagir o intermediário resultante de Fórmula 4 com um composto de Fórmula 5 (ou um sal do mesmo). O composto de Fórmula 1, preparado pelo método acima, pode ser usado para preparar um composto de Fórmula 8 em que R2, R3, R4, m e r são conforme definidos no presente relatório descritivo.
BR112022010520A 2019-12-02 2020-12-02 Processo para síntese de uma 2-tioalquil pirimidina BR112022010520A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962942490P 2019-12-02 2019-12-02
PCT/US2020/062779 WO2021113282A1 (en) 2019-12-02 2020-12-02 Process for synthesis of a 2-thioalkyl pyrimidine

Publications (1)

Publication Number Publication Date
BR112022010520A2 true BR112022010520A2 (pt) 2022-08-16

Family

ID=74046154

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022010520A BR112022010520A2 (pt) 2019-12-02 2020-12-02 Processo para síntese de uma 2-tioalquil pirimidina

Country Status (12)

Country Link
US (1) US20230068064A1 (pt)
EP (1) EP4069679A1 (pt)
JP (1) JP2023503573A (pt)
KR (1) KR20220109428A (pt)
CN (1) CN114761384A (pt)
AU (1) AU2020395117A1 (pt)
BR (1) BR112022010520A2 (pt)
CA (1) CA3162102A1 (pt)
IL (1) IL292898A (pt)
MX (1) MX2022006569A (pt)
TW (1) TW202130623A (pt)
WO (1) WO2021113282A1 (pt)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7326715B2 (en) * 2005-09-23 2008-02-05 N.V. Organon 4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives
WO2007043278A1 (ja) 2005-10-14 2007-04-19 Asahi Glass Company, Limited 塩基性陰イオン交換樹脂の再生方法
UY31774A (es) * 2008-04-22 2009-12-14 Astrazeneca Ab Compuestos de 2-pirimidin-5- ilcarboxamida sustituidos
US8080566B1 (en) 2008-06-11 2011-12-20 Kalypsys, Inc Carbazole inhibitors of histamine receptors for the treatment of disease
SI3094631T1 (sl) * 2014-01-16 2019-05-31 Fmc Corporation Pirimidiniloksi benzen derivati kot herbicidi
RU2735278C2 (ru) * 2015-03-18 2020-10-29 ЭфЭмСи Корпорейшн Замещенные производные пиримидинилокси-пиридина в качестве гербицидов
TW202400564A (zh) * 2015-06-05 2024-01-01 美商艾佛艾姆希公司 作為除草劑之嘧啶氧基苯衍生物

Also Published As

Publication number Publication date
JP2023503573A (ja) 2023-01-31
CA3162102A1 (en) 2021-06-10
MX2022006569A (es) 2022-07-01
TW202130623A (zh) 2021-08-16
EP4069679A1 (en) 2022-10-12
AU2020395117A1 (en) 2022-06-16
US20230068064A1 (en) 2023-03-02
KR20220109428A (ko) 2022-08-04
CN114761384A (zh) 2022-07-15
WO2021113282A1 (en) 2021-06-10
IL292898A (en) 2022-07-01

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