BR112022004927A2 - Bloqueadores de kv1.3 - Google Patents

Bloqueadores de kv1.3

Info

Publication number
BR112022004927A2
BR112022004927A2 BR112022004927A BR112022004927A BR112022004927A2 BR 112022004927 A2 BR112022004927 A2 BR 112022004927A2 BR 112022004927 A BR112022004927 A BR 112022004927A BR 112022004927 A BR112022004927 A BR 112022004927A BR 112022004927 A2 BR112022004927 A2 BR 112022004927A2
Authority
BR
Brazil
Prior art keywords
blockers
same
making
methods
present
Prior art date
Application number
BR112022004927A
Other languages
English (en)
Inventor
Fischer Munch Henrik
Bugge Jensen Rasmus
Kvist Madsen Jens
Original Assignee
Zealand Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zealand Pharma As filed Critical Zealand Pharma As
Publication of BR112022004927A2 publication Critical patent/BR112022004927A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)

Abstract

BLOQUEADORES DE KV1.3. A presente invenção fornece novos bloqueadores do canal de potássio Kv1.3, polinucleotídeos que codificam os mesmos e métodos para produzir e usar os mesmos.
BR112022004927A 2019-09-20 2020-09-18 Bloqueadores de kv1.3 BR112022004927A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19198763 2019-09-20
EP20172989 2020-05-05
PCT/EP2020/076187 WO2021053194A1 (en) 2019-09-20 2020-09-18 Kv1.3 blockers

Publications (1)

Publication Number Publication Date
BR112022004927A2 true BR112022004927A2 (pt) 2022-06-28

Family

ID=72474339

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022004927A BR112022004927A2 (pt) 2019-09-20 2020-09-18 Bloqueadores de kv1.3

Country Status (13)

Country Link
US (3) US11292820B2 (pt)
EP (1) EP4031162A1 (pt)
JP (1) JP2022548956A (pt)
KR (1) KR20220066095A (pt)
CN (1) CN114728039A (pt)
AU (1) AU2020351273A1 (pt)
BR (1) BR112022004927A2 (pt)
CA (1) CA3155089A1 (pt)
CL (1) CL2022000660A1 (pt)
IL (1) IL291303A (pt)
MX (1) MX2022003300A (pt)
TW (1) TW202116350A (pt)
WO (1) WO2021053194A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024511449A (ja) * 2021-03-23 2024-03-13 ジーランド ファーマ エー／エス Ｋｖ１．３遮断薬
WO2023061502A1 (zh) * 2021-10-15 2023-04-20 苏州生物医药转化工程中心 一种双特异性结合分子
WO2024083919A1 (en) * 2022-10-18 2024-04-25 Zealand Pharma A/S Inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69732640T2 (de) 1996-09-09 2006-01-12 Zealand Pharma A/S Festphasen-peptidsynthese
GB0414272D0 (en) 2004-06-25 2004-07-28 Cellpep Sa OsK1 derivatives
JP5118969B2 (ja) 2004-10-07 2013-01-16 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニア Ｋｖ１．３カリウムチャネルの選択的阻害におけるＳｈＫトキシンの類似体ならびにその使用方法
US7833979B2 (en) 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
PE20081140A1 (es) 2006-10-25 2008-09-22 Amgen Inc Agentes terapeuticos a base de peptidos derivados de toxinas
WO2010105184A2 (en) 2009-03-13 2010-09-16 Breach Security , Inc. A method and apparatus for phishing and leeching vulnerability detection
WO2014116937A1 (en) 2013-01-25 2014-07-31 Janssen Biotech, Inc. Kv1.3 antagonists and methods of use
AU2014293270A1 (en) 2013-07-22 2016-02-11 Kineta One, Llc Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof
US20180264080A1 (en) 2015-01-09 2018-09-20 Kineta One, Llc TOPICAL APPLICATIONS OF Kv1.3 CHANNEL BLOCKING PEPTIDES TO TREAT SKIN INFLAMMATION

Also Published As

Publication number Publication date
WO2021053194A1 (en) 2021-03-25
CA3155089A1 (en) 2021-03-25
JP2022548956A (ja) 2022-11-22
US20210380646A1 (en) 2021-12-09
AU2020351273A1 (en) 2022-04-07
US20220251151A1 (en) 2022-08-11
IL291303A (en) 2022-05-01
EP4031162A1 (en) 2022-07-27
MX2022003300A (es) 2022-07-13
CN114728039A (zh) 2022-07-08
TW202116350A (zh) 2021-05-01
US11292820B2 (en) 2022-04-05
KR20220066095A (ko) 2022-05-23
US11780893B2 (en) 2023-10-10
US20240076328A1 (en) 2024-03-07
CL2022000660A1 (es) 2023-04-28

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