BR112021012428A2 - Derivado de dihidropirazolopirazinona tendo atividade inibitória de mgat2 - Google Patents

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Publication number

BR112021012428A2

BR112021012428A2 BR112021012428-4A BR112021012428A BR112021012428A2 BR 112021012428 A2 BR112021012428 A2 BR 112021012428A2 BR 112021012428 A BR112021012428 A BR 112021012428A BR 112021012428 A2 BR112021012428 A2 BR 112021012428A2

Authority

BR

Brazil

Prior art keywords

substituted

unsubstituted

aromatic

compound

substituent group

Prior art date

2019-01-11

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• 230000002401 inhibitory effect Effects 0.000 title claims abstract description 25
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• 150000001875 compounds Chemical class 0.000 claims abstract description 289
• 150000003839 salts Chemical class 0.000 claims abstract description 69
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• 125000003545 alkoxy group Chemical group 0.000 claims description 52
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• 239000001257 hydrogen Substances 0.000 claims description 51
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• 150000002431 hydrogen Chemical class 0.000 claims description 31
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• YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 9
• 239000007864 aqueous solution Substances 0.000 description 9
• 230000015572 biosynthetic process Effects 0.000 description 9
• KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
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