BR112018076904B1 - Método e kit de partes para a remoção de cálculo de um dente - Google Patents
Método e kit de partes para a remoção de cálculo de um dente Download PDFInfo
- Publication number
- BR112018076904B1 BR112018076904B1 BR112018076904-5A BR112018076904A BR112018076904B1 BR 112018076904 B1 BR112018076904 B1 BR 112018076904B1 BR 112018076904 A BR112018076904 A BR 112018076904A BR 112018076904 B1 BR112018076904 B1 BR 112018076904B1
- Authority
- BR
- Brazil
- Prior art keywords
- component
- calculus
- tooth
- hydrogen peroxide
- catalase
- Prior art date
Links
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 148
- 238000000034 method Methods 0.000 claims abstract description 82
- 102000016938 Catalase Human genes 0.000 claims abstract description 55
- 108010053835 Catalase Proteins 0.000 claims abstract description 55
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 21
- 239000001301 oxygen Substances 0.000 claims abstract description 21
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 21
- 239000002243 precursor Substances 0.000 claims abstract description 15
- 239000000203 mixture Substances 0.000 claims description 51
- 150000003839 salts Chemical class 0.000 claims description 16
- 239000002253 acid Substances 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 13
- 150000007513 acids Chemical class 0.000 claims description 10
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 8
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 8
- 150000001451 organic peroxides Chemical class 0.000 claims description 7
- MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical class [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 claims description 7
- 102000004190 Enzymes Human genes 0.000 claims description 5
- 108090000790 Enzymes Proteins 0.000 claims description 5
- 150000002978 peroxides Chemical class 0.000 claims description 5
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 5
- 229940078916 carbamide peroxide Drugs 0.000 claims description 4
- 150000004972 metal peroxides Chemical class 0.000 claims description 4
- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 claims description 4
- 150000004965 peroxy acids Chemical class 0.000 claims description 3
- 239000000499 gel Substances 0.000 description 42
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 25
- 238000007790 scraping Methods 0.000 description 19
- JVTIXNMXDLQEJE-UHFFFAOYSA-N 2-decanoyloxypropyl decanoate 2-octanoyloxypropyl octanoate Chemical compound C(CCCCCCC)(=O)OCC(C)OC(CCCCCCC)=O.C(=O)(CCCCCCCCC)OCC(C)OC(=O)CCCCCCCCC JVTIXNMXDLQEJE-UHFFFAOYSA-N 0.000 description 16
- 230000003068 static effect Effects 0.000 description 16
- 238000011282 treatment Methods 0.000 description 16
- 238000009472 formulation Methods 0.000 description 15
- 239000000243 solution Substances 0.000 description 14
- 208000006558 Dental Calculus Diseases 0.000 description 11
- 206010044029 Tooth deposit Diseases 0.000 description 11
- 235000011187 glycerol Nutrition 0.000 description 11
- 210000003296 saliva Anatomy 0.000 description 11
- 229920002125 Sokalan® Polymers 0.000 description 10
- 239000002562 thickening agent Substances 0.000 description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 9
- 239000004575 stone Substances 0.000 description 9
- 238000002156 mixing Methods 0.000 description 7
- 210000000214 mouth Anatomy 0.000 description 7
- 239000003981 vehicle Substances 0.000 description 7
- 238000004364 calculation method Methods 0.000 description 6
- 241000228245 Aspergillus niger Species 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 229910052791 calcium Inorganic materials 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- 229940088598 enzyme Drugs 0.000 description 4
- 239000003349 gelling agent Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 230000002421 anti-septic effect Effects 0.000 description 3
- 229940064004 antiseptic throat preparations Drugs 0.000 description 3
- 230000001680 brushing effect Effects 0.000 description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 3
- -1 long chain fatty acid alcohols Chemical class 0.000 description 3
- 238000010297 mechanical methods and process Methods 0.000 description 3
- 239000002324 mouth wash Substances 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
- 239000004584 polyacrylic acid Substances 0.000 description 3
- 229920001223 polyethylene glycol Polymers 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 239000000377 silicon dioxide Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 230000002087 whitening effect Effects 0.000 description 3
- 208000012514 Cumulative Trauma disease Diseases 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- 239000004366 Glucose oxidase Substances 0.000 description 2
- 108010015776 Glucose oxidase Proteins 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 208000021642 Muscular disease Diseases 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 description 2
- 102000003992 Peroxidases Human genes 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 102000019197 Superoxide Dismutase Human genes 0.000 description 2
- 108010012715 Superoxide dismutase Proteins 0.000 description 2
- 239000003082 abrasive agent Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 229920001525 carrageenan Polymers 0.000 description 2
- 239000000679 carrageenan Substances 0.000 description 2
- 229940113118 carrageenan Drugs 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical class [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 150000004673 fluoride salts Chemical class 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 229940116332 glucose oxidase Drugs 0.000 description 2
- 235000019420 glucose oxidase Nutrition 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 150000004966 inorganic peroxy acids Chemical class 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 229940051866 mouthwash Drugs 0.000 description 2
- 208000028169 periodontal disease Diseases 0.000 description 2
- 108040007629 peroxidase activity proteins Proteins 0.000 description 2
- 235000021317 phosphate Nutrition 0.000 description 2
- 229920000223 polyglycerol Polymers 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 238000011321 prophylaxis Methods 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- FFTVPQUHLQBXQZ-KVUCHLLUSA-N (4s,4as,5ar,12ar)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1C2=C(N(C)C)C=CC(O)=C2C(O)=C2[C@@H]1C[C@H]1[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]1(O)C2=O FFTVPQUHLQBXQZ-KVUCHLLUSA-N 0.000 description 1
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 description 1
- UBLAMKHIFZBBSS-UHFFFAOYSA-N 3-Methylbutyl pentanoate Chemical compound CCCCC(=O)OCCC(C)C UBLAMKHIFZBBSS-UHFFFAOYSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 241000589155 Agrobacterium tumefaciens Species 0.000 description 1
- 241000122170 Aliivibrio salmonicida Species 0.000 description 1
- 241000256182 Anopheles gambiae Species 0.000 description 1
- 102100030356 Arginase-2, mitochondrial Human genes 0.000 description 1
- 241000351920 Aspergillus nidulans Species 0.000 description 1
- 241000416162 Astragalus gummifer Species 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 239000004343 Calcium peroxide Substances 0.000 description 1
- QDHHCQZDFGDHMP-UHFFFAOYSA-N Chloramine Chemical compound ClN QDHHCQZDFGDHMP-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- 241000206575 Chondrus crispus Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 229920000569 Gum karaya Polymers 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 101000792835 Homo sapiens Arginase-2, mitochondrial Proteins 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- SPAGIJMPHSUYSE-UHFFFAOYSA-N Magnesium peroxide Chemical compound [Mg+2].[O-][O-] SPAGIJMPHSUYSE-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000191938 Micrococcus luteus Species 0.000 description 1
- 208000029578 Muscle disease Diseases 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 229920002413 Polyhexanide Polymers 0.000 description 1
- 229920000388 Polyphosphate Polymers 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 241000934878 Sterculia Species 0.000 description 1
- 239000004098 Tetracycline Substances 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- 229920001938 Vegetable gum Polymers 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 235000010419 agar Nutrition 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 229940009868 aluminum magnesium silicate Drugs 0.000 description 1
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
- 235000021311 artificial sweeteners Nutrition 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- LHJQIRIGXXHNLA-UHFFFAOYSA-N calcium peroxide Chemical compound [Ca+2].[O-][O-] LHJQIRIGXXHNLA-UHFFFAOYSA-N 0.000 description 1
- 235000019402 calcium peroxide Nutrition 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- MMCOUVMKNAHQOY-UHFFFAOYSA-N carbonoperoxoic acid Chemical compound OOC(O)=O MMCOUVMKNAHQOY-UHFFFAOYSA-N 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 229950008138 carmellose Drugs 0.000 description 1
- 208000003295 carpal tunnel syndrome Diseases 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000008119 colloidal silica Substances 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 239000012612 commercial material Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 210000002455 dental arch Anatomy 0.000 description 1
- 235000011180 diphosphates Nutrition 0.000 description 1
- BHDAXLOEFWJKTL-UHFFFAOYSA-L dipotassium;carboxylatooxy carbonate Chemical compound [K+].[K+].[O-]C(=O)OOC([O-])=O BHDAXLOEFWJKTL-UHFFFAOYSA-L 0.000 description 1
- VTIIJXUACCWYHX-UHFFFAOYSA-L disodium;carboxylatooxy carbonate Chemical compound [Na+].[Na+].[O-]C(=O)OOC([O-])=O VTIIJXUACCWYHX-UHFFFAOYSA-L 0.000 description 1
- 238000007323 disproportionation reaction Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- PEYVWSJAZONVQK-UHFFFAOYSA-N hydroperoxy(oxo)borane Chemical compound OOB=O PEYVWSJAZONVQK-UHFFFAOYSA-N 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000010954 inorganic particle Substances 0.000 description 1
- 235000010494 karaya gum Nutrition 0.000 description 1
- 239000000231 karaya gum Substances 0.000 description 1
- 229940039371 karaya gum Drugs 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 229960004995 magnesium peroxide Drugs 0.000 description 1
- DSJNICGAALCLRF-UHFFFAOYSA-L magnesium;oxidooxy(oxo)borane Chemical compound [Mg+2].[O-]OB=O.[O-]OB=O DSJNICGAALCLRF-UHFFFAOYSA-L 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229960004023 minocycline Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 229920001206 natural gum Polymers 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 229960001774 octenidine Drugs 0.000 description 1
- SMGTYJPMKXNQFY-UHFFFAOYSA-N octenidine dihydrochloride Chemical compound Cl.Cl.C1=CC(=NCCCCCCCC)C=CN1CCCCCCCCCCN1C=CC(=NCCCCCCCC)C=C1 SMGTYJPMKXNQFY-UHFFFAOYSA-N 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000011146 organic particle Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 239000013500 performance material Substances 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- MPNNOLHYOHFJKL-UHFFFAOYSA-N peroxyphosphoric acid Chemical compound OOP(O)(O)=O MPNNOLHYOHFJKL-UHFFFAOYSA-N 0.000 description 1
- FHHJDRFHHWUPDG-UHFFFAOYSA-N peroxysulfuric acid Chemical compound OOS(O)(=O)=O FHHJDRFHHWUPDG-UHFFFAOYSA-N 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001515 polyalkylene glycol Polymers 0.000 description 1
- 239000001205 polyphosphate Substances 0.000 description 1
- 235000011176 polyphosphates Nutrition 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000005201 scrubbing Methods 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- 229960001922 sodium perborate Drugs 0.000 description 1
- 229940045872 sodium percarbonate Drugs 0.000 description 1
- YKLJGMBLPUQQOI-UHFFFAOYSA-M sodium;oxidooxy(oxo)borane Chemical compound [Na+].[O-]OB=O YKLJGMBLPUQQOI-UHFFFAOYSA-M 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
- PLVWNARVBMHCST-UHFFFAOYSA-L zinc;oxidooxy(oxo)borane Chemical compound [Zn+2].[O-]OB=O.[O-]OB=O PLVWNARVBMHCST-UHFFFAOYSA-L 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662353407P | 2016-06-22 | 2016-06-22 | |
| US62/353,407 | 2016-06-22 | ||
| PCT/US2017/038471 WO2017223161A1 (en) | 2016-06-22 | 2017-06-21 | Methods and kits of removing calculus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112018076904A2 BR112018076904A2 (pt) | 2019-04-02 |
| BR112018076904B1 true BR112018076904B1 (pt) | 2022-02-08 |
Family
ID=59258409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018076904-5A BR112018076904B1 (pt) | 2016-06-22 | 2017-06-21 | Método e kit de partes para a remoção de cálculo de um dente |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11596590B2 (https=) |
| EP (1) | EP3474818B1 (https=) |
| JP (1) | JP7292037B2 (https=) |
| CN (1) | CN109414392B (https=) |
| BR (1) | BR112018076904B1 (https=) |
| RU (1) | RU2719462C1 (https=) |
| WO (1) | WO2017223161A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016099875A1 (en) | 2014-12-15 | 2016-06-23 | 3M Innovative Properties Company | Methods and kits for removing calculus |
| CN109414392B (zh) | 2016-06-22 | 2022-07-08 | 3M创新有限公司 | 移除结石的方法和试剂盒 |
| BR112019008002A2 (pt) | 2016-10-20 | 2019-07-02 | 3M Innovative Properties Co | métodos e kits para a remoção de cálculo com o uso de um catalisador de decomposição não enzimático de peróxido de hidrogênio |
| US12514792B2 (en) | 2016-10-20 | 2026-01-06 | Solventum Intellectual Properties Company | Methods and kits for removing calculus using a metal ion and bicarbonate |
| EP4419062A1 (en) | 2021-10-20 | 2024-08-28 | Solventum Intellectual Properties Company | Composition and process for treating a disorder in the oral cavity of a mammal |
| US20230149145A1 (en) * | 2021-11-16 | 2023-05-18 | Essential Dental Systems, Inc. | Dual gel colorimetric effervescent dental calculus softening/tooth whitening/ anti-inflammatory cleaning composition with instantaneous mixing via double barrel syringe delivery |
| CN115770208B (zh) * | 2022-12-15 | 2024-12-27 | 中国人民解放军空军军医大学 | 一种牙膏组合物及其制备方法、使用方法和应用 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1482367A (en) | 1922-12-28 | 1924-01-29 | Harvey G Elledge | Production of carbon dioxide |
| US3372125A (en) | 1965-11-15 | 1968-03-05 | Peter Strong & Company Inc | Denture cleanser |
| US3678154A (en) | 1968-07-01 | 1972-07-18 | Procter & Gamble | Oral compositions for calculus retardation |
| US3535421A (en) | 1968-07-11 | 1970-10-20 | Procter & Gamble | Oral compositions for calculus retardation |
| BE755331A (fr) | 1969-09-01 | 1971-02-01 | Blendax Werke Schneider Co | Produits de soins buccaux et dentaires |
| GB1492660A (en) | 1975-10-13 | 1977-11-23 | Colgate Palmolive Co | Dentifrices |
| AU510235B2 (en) | 1975-12-22 | 1980-06-19 | Johnson & Johnson | Denture cleanser tablet |
| AT371338B (de) | 1979-10-30 | 1983-06-27 | Gergely Gerhard | Reinigungstablette fuer zahnprothesen |
| JPS5950280B2 (ja) | 1980-10-24 | 1984-12-07 | 花王株式会社 | 酵素入り漂白剤組成物 |
| US4528180A (en) | 1983-03-01 | 1985-07-09 | Schaeffer Hans A | Dental preparation, article and method for storage and delivery thereof |
| US4522805A (en) * | 1983-06-08 | 1985-06-11 | Norman Gordon | Tooth and gum dentifrice |
| US4894220A (en) | 1987-01-30 | 1990-01-16 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
| FR2627517B1 (fr) | 1988-02-24 | 1990-10-12 | Sandoz Sa | Procede de blanchiment des matieres textiles avec destruction enzymatique de l'exces de peroxyde |
| US5817294A (en) | 1990-11-02 | 1998-10-06 | Arnold; Michael J. | Plaque adsorbent oral composition and method |
| JPH0597640A (ja) | 1991-10-08 | 1993-04-20 | Lion Corp | 義歯洗浄剤 |
| US5403578A (en) | 1994-02-08 | 1995-04-04 | Gordon; Norman | Stable tooth and gum dentifrice with microencapsulation and method for making same |
| EP0691124A1 (en) | 1994-07-07 | 1996-01-10 | Sara Lee/DE N.V. | Mouth care products |
| US5908614A (en) | 1995-08-15 | 1999-06-01 | Montgomery; Robert Eric | Peroxidase-activating oral compositions |
| US6331291B1 (en) * | 1996-05-30 | 2001-12-18 | William R. Glace | Dentifrice gel/paste compositions |
| US6108850A (en) | 1997-06-03 | 2000-08-29 | Mclaughlin; Gerald | Accelerated method and instrumentation for whitening teeth |
| AU740108B2 (en) * | 1997-06-17 | 2001-11-01 | Novozymes A/S | An oral care composition comprising a bacillus pullulanase and a dextranase |
| EP1100927A2 (en) | 1998-07-02 | 2001-05-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for making polyketides using altered pks |
| US6591091B1 (en) * | 1998-11-12 | 2003-07-08 | Broadcom Corporation | System and method for coarse/fine PLL adjustment |
| FR2787778B1 (fr) | 1998-12-23 | 2001-02-23 | Cleani | Compositions comprenant un persel en milieu anhydre, et leurs utilisations |
| US6685921B2 (en) | 2000-10-25 | 2004-02-03 | The Procter & Gamble Company | Dental care compositions |
| US6379654B1 (en) | 2000-10-27 | 2002-04-30 | Colgate Palmolive Company | Oral composition providing enhanced tooth stain removal |
| US6485709B2 (en) | 2001-01-23 | 2002-11-26 | Addent Inc. | Dental bleaching gel composition, activator system and method for activating a dental bleaching gel |
| US6946142B2 (en) | 2001-06-23 | 2005-09-20 | Lg Household & Healthcare Ltd. | Multi-layer patches for teeth whitening |
| JP2003040754A (ja) | 2001-07-26 | 2003-02-13 | Yoshida Dental Mfg Co Ltd | 歯科用研磨剤及び研磨方法 |
| EP2275077A3 (en) | 2001-08-15 | 2014-07-16 | 3M Innovative Properties Co. | Hardenable self-supporting structures and methods |
| JP2004091404A (ja) | 2002-08-30 | 2004-03-25 | Takuro Ishibashi | 歯面清浄剤組成物 |
| JP2004107231A (ja) | 2002-09-17 | 2004-04-08 | Showa Yakuhin Kako Kk | 口腔用組成物 |
| US20040120900A1 (en) * | 2002-12-20 | 2004-06-24 | Peter Arsenault | Intraoral calculus dissolving gel composition |
| US6669929B1 (en) | 2002-12-30 | 2003-12-30 | Colgate Palmolive Company | Dentifrice containing functional film flakes |
| US20050196348A1 (en) | 2004-03-03 | 2005-09-08 | Constantine Georgiades | Stabilized peroxide compositions |
| US7530808B2 (en) | 2004-03-10 | 2009-05-12 | Cao Group, Inc | Binary dental bleaching using switch-closable double barrel syringe |
| US10285789B2 (en) * | 2004-03-10 | 2019-05-14 | Cao Group, Inc. | Dental bleaching gels and methods for making and using them |
| US9028852B2 (en) | 2004-09-07 | 2015-05-12 | 3M Innovative Properties Company | Cationic antiseptic compositions and methods of use |
| WO2006053207A2 (en) | 2004-11-09 | 2006-05-18 | Discus Dental Impressions, Inc | Dental whitening systems comprising transition metal salt activator |
| US9271902B2 (en) | 2005-02-15 | 2016-03-01 | Martin S. Giniger | Whitening system capable of delivering effective whitening action |
| US20070071696A1 (en) | 2005-09-27 | 2007-03-29 | Colgate-Palmolive Company | Dual phase whitening dentifrice |
| JP5628031B2 (ja) | 2007-07-25 | 2014-11-19 | スリーエム イノベイティブ プロパティズ カンパニー | 治療用歯科用組成物及び関連する方法 |
| US7740479B2 (en) | 2007-10-03 | 2010-06-22 | Ultradent Products, Inc. | Activating brush tip applicators for dental bleaching compositions |
| US20090220919A1 (en) | 2008-02-28 | 2009-09-03 | Jen-Chang Yang | Dental Bleaching Gel Composition Containing Vegetative Enzymes |
| WO2009109533A1 (en) | 2008-03-07 | 2009-09-11 | Basf Se | Bleach catalysts and their use as teeth whitening agents |
| RU2432620C1 (ru) | 2010-02-17 | 2011-10-27 | Государственное образовательное учреждение высшего профессионального образования "Омский государственный университет им. Ф.М. Достоевского" | Способ изучения влияния глюкозы на процесс образования зубного камня |
| US20110305738A1 (en) | 2010-06-09 | 2011-12-15 | Ladizinsky Daniel A | Oxygenating Oral Compositions |
| WO2012057917A1 (en) | 2010-10-27 | 2012-05-03 | 3M Innovative Properties Company | Dental compositions comprising semi-crystalline resin and nanocluster filler |
| WO2012072777A1 (en) | 2010-12-01 | 2012-06-07 | B.R.A.I.N. Biotechnology Research And Information Network Ag | Novel catalases |
| US9089479B2 (en) | 2011-05-03 | 2015-07-28 | Fenwal, Inc. | Medium, solutions and methods for the washing, culturing and storage of white blood cells |
| WO2013055478A1 (en) | 2011-10-10 | 2013-04-18 | Ultradent Products, Inc | Anti-plaque dental compositions |
| US20160270879A1 (en) | 2013-11-12 | 2016-09-22 | 3M Innovative Properties Company | Cartridge, a piston and a syringe comprising the cartridge and the piston |
| JP2015113338A (ja) | 2013-12-10 | 2015-06-22 | 川村 弘 | 歯周ポケット内プラークの剥離及び殺菌剤。 |
| CN104173197A (zh) | 2014-08-24 | 2014-12-03 | 秦俊远 | 一种高效美白牙贴 |
| WO2016099875A1 (en) | 2014-12-15 | 2016-06-23 | 3M Innovative Properties Company | Methods and kits for removing calculus |
| CN109414392B (zh) | 2016-06-22 | 2022-07-08 | 3M创新有限公司 | 移除结石的方法和试剂盒 |
| US12514792B2 (en) | 2016-10-20 | 2026-01-06 | Solventum Intellectual Properties Company | Methods and kits for removing calculus using a metal ion and bicarbonate |
| BR112019008002A2 (pt) | 2016-10-20 | 2019-07-02 | 3M Innovative Properties Co | métodos e kits para a remoção de cálculo com o uso de um catalisador de decomposição não enzimático de peróxido de hidrogênio |
-
2017
- 2017-06-21 CN CN201780038733.6A patent/CN109414392B/zh active Active
- 2017-06-21 JP JP2018565010A patent/JP7292037B2/ja active Active
- 2017-06-21 EP EP17734617.8A patent/EP3474818B1/en active Active
- 2017-06-21 BR BR112018076904-5A patent/BR112018076904B1/pt not_active IP Right Cessation
- 2017-06-21 RU RU2018146287A patent/RU2719462C1/ru active
- 2017-06-21 WO PCT/US2017/038471 patent/WO2017223161A1/en not_active Ceased
- 2017-06-21 US US16/305,107 patent/US11596590B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2719462C1 (ru) | 2020-04-17 |
| US20200315942A1 (en) | 2020-10-08 |
| BR112018076904A2 (pt) | 2019-04-02 |
| JP7292037B2 (ja) | 2023-06-16 |
| EP3474818B1 (en) | 2020-05-13 |
| CN109414392B (zh) | 2022-07-08 |
| WO2017223161A1 (en) | 2017-12-28 |
| US11596590B2 (en) | 2023-03-07 |
| EP3474818A1 (en) | 2019-05-01 |
| CN109414392A (zh) | 2019-03-01 |
| JP2019520350A (ja) | 2019-07-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112018076904B1 (pt) | Método e kit de partes para a remoção de cálculo de um dente | |
| US7060256B2 (en) | Increased peroxide content tooth bleaching gel | |
| JPH11500722A (ja) | 歯を漂白するため又は皮膚病訴と粘膜障害とを治療するための製剤の製造方法 | |
| Qing et al. | Cleaning efficacy and dentin micro-hardness after root canal irrigation with a strong acid electrolytic water | |
| JP2007509160A (ja) | 歯のホワイトニングを促進する方法、組成物、及びキット | |
| US20200230038A1 (en) | Methods and kits for removing calculus | |
| Dursun et al. | Which whitening toothpaste with different contents is more effective on color and bond strength of enamel? | |
| JP3710135B2 (ja) | 歯石溶解剤 | |
| WO1999034765A1 (en) | Preparation for dental treatment | |
| CN1630503A (zh) | 洁牙剂的成份 | |
| US20030035779A1 (en) | Biofilm therapy process and elements | |
| Forner et al. | Therapeutic effectiveness of a new enzymatic bleaching dentifrice | |
| US6685474B2 (en) | Aqueous slurries useful for cleaning teeth and methods related thereto | |
| US6582681B1 (en) | Method and a preparation for cleaning tooth root surfaces and surrounding tissue | |
| JP2007126409A (ja) | 歯石溶解剤 | |
| JP4588348B2 (ja) | 歯石及びウ蝕部除去剤 | |
| JP2005139201A (ja) | 歯石及びウ蝕部溶解剤 | |
| Shukla et al. | Chemo Mechanical Caries Removal Technique: A Review Article on Lost and Found Approach towards Painless Dentistry. | |
| JP2000136119A (ja) | 虫歯予防用組成物 | |
| CN100350901C (zh) | 牙石及龋蚀部分溶解剂 | |
| JP2007008839A (ja) | 歯石染色剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/06/2017, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2728 DE 18-04-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |