BR112018016874A2 - métodos e composições para distribuição de arilsulfatase a no sistema nervoso central (snc) - Google Patents
métodos e composições para distribuição de arilsulfatase a no sistema nervoso central (snc)Info
- Publication number
- BR112018016874A2 BR112018016874A2 BR112018016874A BR112018016874A BR112018016874A2 BR 112018016874 A2 BR112018016874 A2 BR 112018016874A2 BR 112018016874 A BR112018016874 A BR 112018016874A BR 112018016874 A BR112018016874 A BR 112018016874A BR 112018016874 A2 BR112018016874 A2 BR 112018016874A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- arylsulfatase
- snc
- distributing
- compositions
- Prior art date
Links
- 102100022146 Arylsulfatase A Human genes 0.000 title 1
- 108010036867 Cerebroside-Sulfatase Proteins 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000009133 Arylsulfatases Human genes 0.000 abstract 1
- 201000011442 Metachromatic leukodystrophy Diseases 0.000 abstract 1
- 108060007951 sulfatase Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/06—Sulfuric ester hydrolases (3.1.6)
- C12Y301/06001—Arylsulfatase (3.1.6.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662296563P | 2016-02-17 | 2016-02-17 | |
| US201762453864P | 2017-02-02 | 2017-02-02 | |
| PCT/US2017/018440 WO2017143233A1 (en) | 2016-02-17 | 2017-02-17 | Methods and compositions for cns delivery of arylsulfatase a |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018016874A2 true BR112018016874A2 (pt) | 2019-02-05 |
Family
ID=58192404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018016874A BR112018016874A2 (pt) | 2016-02-17 | 2017-02-17 | métodos e composições para distribuição de arilsulfatase a no sistema nervoso central (snc) |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11020461B2 (https=) |
| EP (1) | EP3416678A1 (https=) |
| JP (4) | JP2019509270A (https=) |
| CN (2) | CN108883162A (https=) |
| AU (1) | AU2017220100B2 (https=) |
| BR (1) | BR112018016874A2 (https=) |
| CA (1) | CA3014909A1 (https=) |
| MA (1) | MA44237A (https=) |
| MX (2) | MX2018009937A (https=) |
| WO (1) | WO2017143233A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019126376A1 (en) * | 2017-12-19 | 2019-06-27 | Shire Human Genetic Therapies, Inc. | Purified arylsulfatase a and compositons thereof |
| BR112021021908A2 (pt) * | 2019-05-03 | 2022-02-01 | Univ Pennsylvania | Composições úteis no tratamento da leucodistrofia metacromática |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6217552B1 (en) | 1999-03-01 | 2001-04-17 | Coaxia, Inc. | Medical device for selective intrathecal spinal cooling in aortic surgery and spinal trauma |
| US6537785B1 (en) | 1999-09-14 | 2003-03-25 | Genzyme Glycobiology Research Institute, Inc. | Methods of treating lysosomal storage diseases |
| NZ605874A (en) * | 2010-06-25 | 2015-02-27 | Shire Human Genetic Therapies | Methods and compositions for cns delivery of heparan n-sulfatase |
| SMT201600385T1 (it) * | 2010-06-25 | 2017-03-08 | Shire Human Genetic Therapies | Trasporto di agenti terapeutici all’snc |
| NZ605873A (en) * | 2010-06-25 | 2015-02-27 | Shire Human Genetic Therapies | Methods and compositions for cns delivery of arylsulfatase a |
| CN103179980B (zh) * | 2010-06-25 | 2016-09-28 | 夏尔人类遗传性治疗公司 | 艾杜糖醛酸-2-硫酸酯酶的cns递送的方法和组合物 |
-
2017
- 2017-02-17 EP EP17708395.3A patent/EP3416678A1/en not_active Withdrawn
- 2017-02-17 AU AU2017220100A patent/AU2017220100B2/en active Active
- 2017-02-17 WO PCT/US2017/018440 patent/WO2017143233A1/en not_active Ceased
- 2017-02-17 MX MX2018009937A patent/MX2018009937A/es unknown
- 2017-02-17 JP JP2018543324A patent/JP2019509270A/ja active Pending
- 2017-02-17 US US15/999,472 patent/US11020461B2/en active Active
- 2017-02-17 CA CA3014909A patent/CA3014909A1/en active Pending
- 2017-02-17 BR BR112018016874A patent/BR112018016874A2/pt unknown
- 2017-02-17 MA MA044237A patent/MA44237A/fr unknown
- 2017-02-17 CN CN201780022756.8A patent/CN108883162A/zh active Pending
- 2017-02-17 CN CN202311189440.1A patent/CN117224659A/zh active Pending
-
2018
- 2018-08-16 MX MX2024004034A patent/MX2024004034A/es unknown
-
2021
- 2021-04-30 US US17/246,119 patent/US20210315981A1/en not_active Abandoned
- 2021-07-29 JP JP2021124414A patent/JP2021169528A/ja not_active Withdrawn
-
2023
- 2023-08-29 JP JP2023138821A patent/JP2023159405A/ja active Pending
-
2024
- 2024-05-21 JP JP2024082556A patent/JP2024102370A/ja active Pending
- 2024-09-10 US US18/829,900 patent/US20250099555A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3416678A1 (en) | 2018-12-26 |
| WO2017143233A1 (en) | 2017-08-24 |
| US20210315981A1 (en) | 2021-10-14 |
| AU2017220100B2 (en) | 2024-04-04 |
| CN108883162A (zh) | 2018-11-23 |
| JP2023159405A (ja) | 2023-10-31 |
| MX2024004034A (es) | 2024-04-24 |
| MX2018009937A (es) | 2018-11-29 |
| AU2017220100A1 (en) | 2018-08-30 |
| CN117224659A (zh) | 2023-12-15 |
| US20250099555A1 (en) | 2025-03-27 |
| US11020461B2 (en) | 2021-06-01 |
| JP2024102370A (ja) | 2024-07-30 |
| CA3014909A1 (en) | 2017-08-24 |
| JP2021169528A (ja) | 2021-10-28 |
| MA44237A (fr) | 2021-06-02 |
| JP2019509270A (ja) | 2019-04-04 |
| US20200179492A1 (en) | 2020-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) |
|
| B25L | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled |
Owner name: SHIRE HUMAN GENETIC THERAPIES, INC. (US) Free format text: ANULADA A PUBLICACAO CODIGO 25.1 NA RPI NO 2648 DE 05/10/2021 POR TER SIDO INDEVIDA. |
|
| B25A | Requested transfer of rights approved |
Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) |
|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |