BR112015031813A2 - composições e métodos para melhorar a mobilização de células-tronco - Google Patents

composições e métodos para melhorar a mobilização de células-tronco

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Publication number
BR112015031813A2
BR112015031813A2 BR112015031813A BR112015031813A BR112015031813A2 BR 112015031813 A2 BR112015031813 A2 BR 112015031813A2 BR 112015031813 A BR112015031813 A BR 112015031813A BR 112015031813 A BR112015031813 A BR 112015031813A BR 112015031813 A2 BR112015031813 A2 BR 112015031813A2
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BR
Brazil
Prior art keywords
stem cell
stem cells
methods
hscs
migration
Prior art date
Application number
BR112015031813A
Other languages
English (en)
Inventor
Drapeau Christian
S Jensen Gitte
Original Assignee
Stemtech Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemtech Int Inc filed Critical Stemtech Int Inc
Publication of BR112015031813A2 publication Critical patent/BR112015031813A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/748—Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/066—Clavicipitaceae
    • A61K36/068—Cordyceps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)

Abstract

resumo da patente de invenã§ã£o para: “composiã‡ã•es e mã‰todos para melhorar a mobilizaã‡ãƒo de cã‰lulas-tronco”. a presente invenã§ã£o proporciona um mã©todo de utilizaã§ã£o de agentes de mobilizaã§ã£o para aumentar a mobilizaã§ã£o das cã©lulas-tronco num sujeito, incluindo as cã©lulas-tronco hematopoiã©ticas (hscs) e de cã©lulas-tronco da medula ã³ssea (bmsc). numa modalidade, uma composiã§ã£o misturada de frutas, cogumelos, micro-organismos, fluidos maternos, e os seus extratos, sã£o utilizados para promover o trã¡fico de cã©lulas-tronco, o que resulta na migraã§ã£o das cã©lulas-tronco para pocilgas especã­ficos da manutenã§ã£o e a reparaã§ã£o dentro dos tecidos e/ou ã³rgã£os. o aumento da circulaã§ã£o de hscs e/ou bmscs e migraã§ã£o para sã­tios de manutenã§ã£o e os mecanismos de regeneraã§ã£o natural no corpo. proporciona-se um regime de dosagem para a administraã§ã£o de fucoidano e a um mã©todo de aumentar a libertaã§ã£o de circulaã§ã£o e das cã©lulas-tronco.
BR112015031813A 2013-06-19 2014-06-19 composições e métodos para melhorar a mobilização de células-tronco BR112015031813A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361837045P 2013-06-19 2013-06-19
PCT/US2014/043237 WO2014205250A1 (en) 2013-06-19 2014-06-19 Methods and compositions for enhancing stem cell mobilization

Publications (1)

Publication Number Publication Date
BR112015031813A2 true BR112015031813A2 (pt) 2017-07-25

Family

ID=52105299

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015031813A BR112015031813A2 (pt) 2013-06-19 2014-06-19 composições e métodos para melhorar a mobilização de células-tronco

Country Status (13)

Country Link
US (1) US20160136225A1 (pt)
EP (1) EP3010482A4 (pt)
JP (1) JP2016522265A (pt)
KR (1) KR20160021182A (pt)
AU (1) AU2014281338A1 (pt)
BR (1) BR112015031813A2 (pt)
CA (1) CA2912185A1 (pt)
HK (1) HK1223826A1 (pt)
MX (1) MX2015017555A (pt)
PH (1) PH12015502827A1 (pt)
RU (1) RU2016101222A (pt)
SG (1) SG11201509437XA (pt)
WO (1) WO2014205250A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10159705B2 (en) 2010-06-28 2018-12-25 Stemtech IP Holdings, LLC Methods and compositions for enhancing stem cell mobilization
WO2013074801A1 (en) 2011-11-18 2013-05-23 Stemtech International, Inc. Use of foti to enhance stem cell mobilization and proliferation
CN105852125A (zh) * 2016-04-27 2016-08-17 深圳爱生再生医学科技有限公司 芦荟干细胞冻干粉及其制备方法和应用
US20180021326A1 (en) * 2016-07-23 2018-01-25 Paul Edward Stamets Compositions and methods for enhancing neuroregeneration and cognition by combining mushroom extracts containing active ingredients psilocin or psilocybin with erinacines or hericenones enhanced with niacin
JP7076709B2 (ja) * 2016-08-18 2022-05-30 北海道公立大学法人 札幌医科大学 間葉系幹細胞活性化剤
CN110192623A (zh) * 2019-07-05 2019-09-03 福建冠丰生物科技有限公司 一种海参牡蛎复合型营养低聚肽粉及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1282952B1 (it) * 1996-01-24 1998-04-02 Silvie Limited Formulazioni farmaceutiche gastroresistenti contenenti colostro e uso del colostro per il trattamento della costipazione
CA2435196A1 (fr) * 2003-07-21 2005-01-21 Thi Thanh Nguyen Methode de traitement radical et etiologique contre les rides et vieillissement precoces
MA29706B1 (fr) * 2007-02-14 2008-09-01 Philippe Alleon Complement alimentaire comprenant de la spiruline et un produit a base de plante du genre aloe, et son utilisation cosmetique
US10159705B2 (en) * 2010-06-28 2018-12-25 Stemtech IP Holdings, LLC Methods and compositions for enhancing stem cell mobilization
BR112014002626A2 (pt) * 2011-08-05 2017-04-04 Stemtech Int Inc composições de cuidados da pele que contêm combinações de ingredientes naturais
WO2013074801A1 (en) * 2011-11-18 2013-05-23 Stemtech International, Inc. Use of foti to enhance stem cell mobilization and proliferation

Also Published As

Publication number Publication date
MX2015017555A (es) 2016-04-26
PH12015502827A1 (en) 2016-03-21
WO2014205250A1 (en) 2014-12-24
EP3010482A4 (en) 2016-11-02
KR20160021182A (ko) 2016-02-24
US20160136225A1 (en) 2016-05-19
RU2016101222A (ru) 2017-07-24
CA2912185A1 (en) 2014-12-24
EP3010482A1 (en) 2016-04-27
SG11201509437XA (en) 2015-12-30
AU2014281338A1 (en) 2015-11-26
JP2016522265A (ja) 2016-07-28
HK1223826A1 (zh) 2017-08-11

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B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]