BR112015023088A2 - método para preparar um composto, e, composto - Google Patents
método para preparar um composto, e, compostoInfo
- Publication number
- BR112015023088A2 BR112015023088A2 BR112015023088A BR112015023088A BR112015023088A2 BR 112015023088 A2 BR112015023088 A2 BR 112015023088A2 BR 112015023088 A BR112015023088 A BR 112015023088A BR 112015023088 A BR112015023088 A BR 112015023088A BR 112015023088 A2 BR112015023088 A2 BR 112015023088A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- preparing
- formula
- methods
- certain intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/02—Formation of carboxyl groups in compounds containing amino groups, e.g. by oxidation of amino alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
Abstract
1 / 1 resumo âmãtodo para preparar um composto, e, compostoâ sã£o aqui fornecidos mã©todos para preparar o composto da fã³rmula i e determinados intermediã¡rios envolvidos em tal processo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361791909P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/029674 WO2014145035A1 (en) | 2013-03-15 | 2014-03-14 | Methods of making cancer compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015023088A2 true BR112015023088A2 (pt) | 2017-11-21 |
Family
ID=51537866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015023088A BR112015023088A2 (pt) | 2013-03-15 | 2014-03-14 | método para preparar um composto, e, composto |
Country Status (15)
Country | Link |
---|---|
US (3) | US9446141B2 (pt) |
EP (1) | EP2967072A4 (pt) |
JP (1) | JP2016518339A (pt) |
KR (1) | KR20150132225A (pt) |
CN (1) | CN105722394A (pt) |
AU (1) | AU2014233421A1 (pt) |
BR (1) | BR112015023088A2 (pt) |
CA (1) | CA2903599A1 (pt) |
CL (1) | CL2015002584A1 (pt) |
EA (1) | EA201591449A1 (pt) |
HK (1) | HK1213740A1 (pt) |
IL (1) | IL241149A0 (pt) |
MX (1) | MX2015012523A (pt) |
SG (1) | SG11201506953RA (pt) |
WO (1) | WO2014145035A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2967072A4 (en) * | 2013-03-15 | 2016-11-16 | METHODS OF MANUFACTURING COMPOSITIONS FOR THE TREATMENT OF CANCER | |
TW201618768A (zh) * | 2014-11-18 | 2016-06-01 | 琴史匹亞公司 | 製造前藥及靶定治療性化合物之方法 |
US11659854B2 (en) | 2017-07-13 | 2023-05-30 | Fuji Oil Holdings Inc. | Method for imparting body taste to food |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5948919A (en) * | 1993-02-05 | 1999-09-07 | Napro Biotherapeutics, Inc. | Paclitaxel synthesis from precursor compounds and methods of producing the same |
US6504014B1 (en) * | 1997-05-19 | 2003-01-07 | The John Hopkins University | Tissue specific prodrug |
AU2002239403A1 (en) * | 2000-12-01 | 2002-06-11 | The Johns Hopkins University | Tissue specific prodrugs |
US9107863B2 (en) * | 2006-03-27 | 2015-08-18 | The Buck Institute For Age Reasearch | Reagents and methods for cancer treatment and prevention |
JP2012516852A (ja) * | 2009-02-02 | 2012-07-26 | マーテック バイオサイエンシーズ コーポレーション | 認知機能改善および心拍数低下のための方法 |
US8772226B2 (en) * | 2009-03-17 | 2014-07-08 | The Johns Hopkins University | Methods and compositions for the detection of cancer |
EP2967072A4 (en) * | 2013-03-15 | 2016-11-16 | METHODS OF MANUFACTURING COMPOSITIONS FOR THE TREATMENT OF CANCER |
-
2014
- 2014-03-14 EP EP14764564.2A patent/EP2967072A4/en not_active Withdrawn
- 2014-03-14 SG SG11201506953RA patent/SG11201506953RA/en unknown
- 2014-03-14 BR BR112015023088A patent/BR112015023088A2/pt not_active Application Discontinuation
- 2014-03-14 AU AU2014233421A patent/AU2014233421A1/en not_active Abandoned
- 2014-03-14 MX MX2015012523A patent/MX2015012523A/es unknown
- 2014-03-14 JP JP2016503190A patent/JP2016518339A/ja active Pending
- 2014-03-14 US US14/776,730 patent/US9446141B2/en not_active Expired - Fee Related
- 2014-03-14 EA EA201591449A patent/EA201591449A1/ru unknown
- 2014-03-14 CN CN201480013662.0A patent/CN105722394A/zh active Pending
- 2014-03-14 KR KR1020157027332A patent/KR20150132225A/ko not_active Application Discontinuation
- 2014-03-14 WO PCT/US2014/029674 patent/WO2014145035A1/en active Application Filing
- 2014-03-14 CA CA2903599A patent/CA2903599A1/en not_active Abandoned
-
2015
- 2015-09-03 IL IL241149A patent/IL241149A0/en unknown
- 2015-09-10 CL CL2015002584A patent/CL2015002584A1/es unknown
-
2016
- 2016-02-23 HK HK16101956.2A patent/HK1213740A1/zh unknown
- 2016-08-09 US US15/232,599 patent/US9845283B2/en not_active Expired - Fee Related
- 2016-08-09 US US15/232,590 patent/US9822064B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EA201591449A1 (ru) | 2016-04-29 |
US20160347706A1 (en) | 2016-12-01 |
MX2015012523A (es) | 2016-04-26 |
KR20150132225A (ko) | 2015-11-25 |
HK1213740A1 (zh) | 2016-07-15 |
EP2967072A4 (en) | 2016-11-16 |
US9845283B2 (en) | 2017-12-19 |
US9446141B2 (en) | 2016-09-20 |
CN105722394A (zh) | 2016-06-29 |
SG11201506953RA (en) | 2015-10-29 |
WO2014145035A8 (en) | 2016-04-14 |
CA2903599A1 (en) | 2014-09-18 |
EP2967072A1 (en) | 2016-01-20 |
IL241149A0 (en) | 2015-11-30 |
AU2014233421A1 (en) | 2015-09-24 |
JP2016518339A (ja) | 2016-06-23 |
CL2015002584A1 (es) | 2016-02-26 |
US20160030589A1 (en) | 2016-02-04 |
US9822064B2 (en) | 2017-11-21 |
WO2014145035A1 (en) | 2014-09-18 |
US20160347730A1 (en) | 2016-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |