BR112015022223A2 - topical compositions and methods of treating topical disorders - Google Patents
topical compositions and methods of treating topical disordersInfo
- Publication number
- BR112015022223A2 BR112015022223A2 BR112015022223A BR112015022223A BR112015022223A2 BR 112015022223 A2 BR112015022223 A2 BR 112015022223A2 BR 112015022223 A BR112015022223 A BR 112015022223A BR 112015022223 A BR112015022223 A BR 112015022223A BR 112015022223 A2 BR112015022223 A2 BR 112015022223A2
- Authority
- BR
- Brazil
- Prior art keywords
- topical
- film
- body surface
- composition
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Abstract
resumo patente de invenção: "composições tópicas e métodos de tratamento de distúrbios tópicos". a presente invenção refere-se a uma composição tópica que inclui pelo menos um ingrediente formador de filme; pelo menos um tensoativo; pelo menos um solvente de siloxano volátil não polar; pelo menos 15% (p/p) de água; e uma concentração terapeuticamente eficaz de pelo menos um agente farmacêutico, em que a composição é suficientemente projetada para secar em 60 segundos após a aplicação a uma superfície corporal para formar uma composição seca e em que a composição seca forma: um filme flexível, em que o filme flexível segue de perto as irregularidades da superfície corporal bem como o movimento da superfície corporal, e (ii) um filme durável, em que o filme durável não racha ou descama e permanece intacto por mais de 12 horas, proporcionando a liberação do agente farmacêutico por um período de tempo estendido. 1/1Patent Summary: "Topical compositions and methods of treating topical disorders". The present invention relates to a topical composition comprising at least one film-forming ingredient; at least one surfactant; at least one nonpolar volatile siloxane solvent; at least 15% (w / w) water; and a therapeutically effective concentration of at least one pharmaceutical agent, wherein the composition is sufficiently designed to dry within 60 seconds after application to a body surface to form a dry composition and wherein the dry composition forms: a flexible film wherein the flexible film closely follows body surface irregularities as well as body surface movement, and (ii) a durable film in which the durable film does not crack or peel and remains intact for more than 12 hours, providing agent release pharmacist for an extended period of time. 1/1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361775598P | 2013-03-10 | 2013-03-10 | |
US61/775,598 | 2013-03-10 | ||
IB2014140925 | 2014-09-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015022223A2 true BR112015022223A2 (en) | 2017-07-18 |
BR112015022223B1 BR112015022223B1 (en) | 2022-06-28 |
Family
ID=51488109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015022223-4A BR112015022223B1 (en) | 2013-03-10 | 2014-03-10 | TOPICAL COMPOSITION, ITS USE, AND KIT |
Country Status (12)
Country | Link |
---|---|
US (5) | US9072747B2 (en) |
EP (1) | EP2968133A4 (en) |
JP (1) | JP2016510807A (en) |
KR (1) | KR20150136077A (en) |
CN (1) | CN105142611B (en) |
AU (1) | AU2014229497A1 (en) |
BR (1) | BR112015022223B1 (en) |
CA (1) | CA2904507C (en) |
IL (1) | IL241191B (en) |
MX (1) | MX2015012302A (en) |
RU (1) | RU2670750C9 (en) |
WO (1) | WO2014140925A2 (en) |
Families Citing this family (21)
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CA2904507C (en) | 2013-03-10 | 2021-05-04 | Peritech Pharma Ltd. | Topical compositions and methods of treatment of topical disorders |
WO2014183055A1 (en) | 2013-05-10 | 2014-11-13 | M. Alphabet 2, L.L.C. | Methods of treating skin conditions using cyclolignan compounds |
US20150366798A1 (en) * | 2014-06-19 | 2015-12-24 | Evgenia Lozinsky | Pharmaceutical adhesive compositions for treatment of epistaxis and methods of use thereof |
AU2015297021A1 (en) * | 2014-07-31 | 2017-03-02 | Kimberly-Clark Worldwide, Inc. | Anti-adherent composition |
WO2016178053A1 (en) * | 2015-05-01 | 2016-11-10 | Lozinsky Evgenia | Compositions for the treatment of epistaxis |
WO2017024029A1 (en) * | 2015-08-03 | 2017-02-09 | Synergistic Therapeutics, Llc | Sexual dysfunction therapeutic gel |
WO2017040420A1 (en) * | 2015-08-28 | 2017-03-09 | C.B. Fleet Company, Incorporated | Hemorrhoid preparation and sheets |
ES2905445T3 (en) * | 2016-10-21 | 2022-04-08 | Crescita Therapeutics Inc | Pharmaceutical compositions |
WO2019064165A1 (en) * | 2017-09-28 | 2019-04-04 | Zenvision Pharma Llp | Synergistic pharmaceutical composition of acyclovir or penciclovir, docosanol and hydrocortisone |
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
AT521126A2 (en) * | 2018-03-29 | 2019-10-15 | Bcsk Biocid Gmbh | Sprühpflasterzusammensetzung |
EP3955936A1 (en) | 2019-04-17 | 2022-02-23 | COMPASS Pathfinder Limited | Treatment of depression and other various disorders with psilocybin |
WO2020252252A1 (en) | 2019-06-14 | 2020-12-17 | Propella Therapeutics, Inc. | Topical acyclovir formulations and uses thereof |
IL291839A (en) | 2019-10-01 | 2022-06-01 | Empyrean Neuroscience Inc | Genetic engineering of fungi to modulate tryptamine expression |
CN110585312A (en) * | 2019-10-18 | 2019-12-20 | 北京博达绿洲医药科技研究有限公司 | Liduodeoxyemulsion and preparation method and application thereof |
CN111374938B (en) * | 2020-03-19 | 2020-12-22 | 广州杨森药业有限公司 | Oil-free gel containing azelaic acid and preparation method thereof |
MX2022014605A (en) | 2020-05-19 | 2022-12-16 | Cybin Irl Ltd | Deuterated tryptamine derivatives and methods of use. |
CA3085078A1 (en) * | 2020-06-29 | 2021-12-29 | Napoleon Savescu | Medicament, compound, composition and method for treating herpes |
CN117377461A (en) * | 2021-04-01 | 2024-01-09 | 钢铁疗法公司 | Topical wipe containing nifedipine and lidocaine |
WO2023172216A1 (en) * | 2022-03-11 | 2023-09-14 | Ilko Ilac Sanayi Ve Ticaret A.S. | Hydrocortisone and pramoxine topical formulations having enhanced in-vitro release |
CN115518031A (en) * | 2022-10-28 | 2022-12-27 | 云飞生物药业(吉林)有限公司 | Carbomer hemorrhoid gel |
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-
2014
- 2014-03-10 CA CA2904507A patent/CA2904507C/en not_active Expired - Fee Related
- 2014-03-10 EP EP14764960.2A patent/EP2968133A4/en not_active Withdrawn
- 2014-03-10 RU RU2015143158A patent/RU2670750C9/en active
- 2014-03-10 MX MX2015012302A patent/MX2015012302A/en unknown
- 2014-03-10 BR BR112015022223-4A patent/BR112015022223B1/en not_active IP Right Cessation
- 2014-03-10 AU AU2014229497A patent/AU2014229497A1/en not_active Abandoned
- 2014-03-10 US US14/203,295 patent/US9072747B2/en not_active Expired - Fee Related
- 2014-03-10 WO PCT/IB2014/001233 patent/WO2014140925A2/en active Application Filing
- 2014-03-10 US US14/203,329 patent/US20140255522A1/en not_active Abandoned
- 2014-03-10 KR KR1020157026948A patent/KR20150136077A/en not_active Application Discontinuation
- 2014-03-10 CN CN201480021297.8A patent/CN105142611B/en not_active Expired - Fee Related
- 2014-03-10 US US14/203,246 patent/US10085994B2/en active Active - Reinstated
- 2014-03-10 JP JP2015562408A patent/JP2016510807A/en active Pending
-
2015
- 2015-06-16 US US14/740,821 patent/US10085995B2/en not_active Expired - Fee Related
- 2015-09-06 IL IL241191A patent/IL241191B/en active IP Right Grant
-
2018
- 2018-08-10 US US16/100,432 patent/US20180344743A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20140255521A1 (en) | 2014-09-11 |
EP2968133A2 (en) | 2016-01-20 |
CN105142611B (en) | 2019-06-04 |
US20150272957A1 (en) | 2015-10-01 |
JP2016510807A (en) | 2016-04-11 |
KR20150136077A (en) | 2015-12-04 |
RU2670750C9 (en) | 2018-12-13 |
AU2014229497A1 (en) | 2015-09-24 |
CA2904507C (en) | 2021-05-04 |
US10085995B2 (en) | 2018-10-02 |
CN105142611A (en) | 2015-12-09 |
RU2015143158A3 (en) | 2018-03-20 |
BR112015022223B1 (en) | 2022-06-28 |
US20180344743A1 (en) | 2018-12-06 |
WO2014140925A3 (en) | 2015-07-30 |
US9072747B2 (en) | 2015-07-07 |
RU2015143158A (en) | 2017-04-18 |
US20140256688A1 (en) | 2014-09-11 |
WO2014140925A2 (en) | 2014-09-18 |
EP2968133A4 (en) | 2016-03-09 |
IL241191B (en) | 2020-02-27 |
US20140255522A1 (en) | 2014-09-11 |
US10085994B2 (en) | 2018-10-02 |
IL241191A0 (en) | 2015-11-30 |
CA2904507A1 (en) | 2014-09-18 |
RU2670750C2 (en) | 2018-10-25 |
MX2015012302A (en) | 2016-06-21 |
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