BR112015002727B1 - Combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmacêutica - Google Patents

Combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmacêutica Download PDF

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Publication number
BR112015002727B1
BR112015002727B1 BR112015002727-0A BR112015002727A BR112015002727B1 BR 112015002727 B1 BR112015002727 B1 BR 112015002727B1 BR 112015002727 A BR112015002727 A BR 112015002727A BR 112015002727 B1 BR112015002727 B1 BR 112015002727B1
Authority
BR
Brazil
Prior art keywords
dab
combination
pharmaceutical composition
infections
compounds
Prior art date
Application number
BR112015002727-0A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112015002727A2 (pt
Inventor
Glenn E. Dale
Daniel Obrecht
Francesca Bernardini
Original Assignee
Polyphor Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyphor Ag filed Critical Polyphor Ag
Publication of BR112015002727A2 publication Critical patent/BR112015002727A2/pt
Publication of BR112015002727B1 publication Critical patent/BR112015002727B1/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
BR112015002727-0A 2012-08-08 2013-08-07 Combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmacêutica BR112015002727B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12005744.3 2012-08-08
EP12005744 2012-08-08
PCT/EP2013/066530 WO2014023757A1 (en) 2012-08-08 2013-08-07 Combinations with a backbone-cyclized peptide

Publications (2)

Publication Number Publication Date
BR112015002727A2 BR112015002727A2 (pt) 2017-08-08
BR112015002727B1 true BR112015002727B1 (pt) 2022-09-06

Family

ID=46796226

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015002727-0A BR112015002727B1 (pt) 2012-08-08 2013-08-07 Combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmacêutica

Country Status (25)

Country Link
US (1) US9775877B2 (https=)
EP (1) EP2882770B1 (https=)
JP (2) JP6486270B2 (https=)
KR (1) KR102167324B1 (https=)
CN (1) CN104684925B (https=)
AU (1) AU2013301567B2 (https=)
BR (1) BR112015002727B1 (https=)
CA (1) CA2879207C (https=)
CY (1) CY1119308T1 (https=)
DK (1) DK2882770T3 (https=)
EA (1) EA030077B1 (https=)
ES (1) ES2639165T3 (https=)
HR (1) HRP20171299T1 (https=)
HU (1) HUE035891T2 (https=)
IL (1) IL236697B (https=)
LT (1) LT2882770T (https=)
MX (2) MX366997B (https=)
NZ (1) NZ703729A (https=)
PL (1) PL2882770T3 (https=)
PT (1) PT2882770T (https=)
RS (1) RS56249B1 (https=)
SG (1) SG11201500216TA (https=)
SI (1) SI2882770T1 (https=)
WO (1) WO2014023757A1 (https=)
ZA (1) ZA201500278B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2132221T3 (pl) 2007-02-28 2011-04-29 Polyphor Ltd Przyłączone do matrycy peptydomimetyki
EP2882770B1 (en) * 2012-08-08 2017-05-31 Polyphor AG Combinations with a backbone-cyclized peptide
JP2023549971A (ja) * 2020-11-23 2023-11-29 スペクシス アーゲー ベータヘアピン型ペプチド模倣物の組成物及びそのエアロゾル投与形態

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2527339T3 (es) 2001-02-23 2015-01-23 Polyphor Ltd. Peptidomiméticos fijados a patrón con actividad antimicrobiana
JP4221368B2 (ja) 2002-08-20 2009-02-12 ポリファー リミテッド 抗菌活性を有するテンプレート結合ペプチド擬似体
WO2007079597A1 (en) * 2006-01-16 2007-07-19 Polyphor Ltd. Template - fixed peptidomimetics with antimicrobial activity
PL2132221T3 (pl) * 2007-02-28 2011-04-29 Polyphor Ltd Przyłączone do matrycy peptydomimetyki
WO2010017273A2 (en) * 2008-08-06 2010-02-11 Wyeth Tigecycline formulations
EP2882770B1 (en) * 2012-08-08 2017-05-31 Polyphor AG Combinations with a backbone-cyclized peptide

Also Published As

Publication number Publication date
KR102167324B1 (ko) 2020-10-20
JP2018087191A (ja) 2018-06-07
WO2014023757A1 (en) 2014-02-13
EP2882770A1 (en) 2015-06-17
IL236697B (en) 2020-02-27
MX2019002657A (es) 2019-07-15
CA2879207A1 (en) 2014-02-13
US9775877B2 (en) 2017-10-03
HRP20171299T1 (hr) 2017-10-20
US20150216927A1 (en) 2015-08-06
CN104684925A (zh) 2015-06-03
CN104684925B (zh) 2021-11-30
DK2882770T3 (en) 2017-09-18
EP2882770B1 (en) 2017-05-31
EA030077B1 (ru) 2018-06-29
CY1119308T1 (el) 2018-02-14
ES2639165T3 (es) 2017-10-25
HK1207866A1 (en) 2016-02-12
NZ703729A (en) 2018-03-23
KR20150038612A (ko) 2015-04-08
CA2879207C (en) 2021-02-16
EA201590351A1 (ru) 2016-05-31
JP2015524460A (ja) 2015-08-24
AU2013301567B2 (en) 2017-08-03
BR112015002727A2 (pt) 2017-08-08
ZA201500278B (en) 2016-01-27
JP6486270B2 (ja) 2019-03-20
MX366997B (es) 2019-08-02
PL2882770T3 (pl) 2018-01-31
MX2015001685A (es) 2015-04-10
AU2013301567A1 (en) 2015-02-05
SG11201500216TA (en) 2015-03-30
SI2882770T1 (sl) 2017-10-30
HUE035891T2 (en) 2018-05-28
RS56249B1 (sr) 2017-11-30
IL236697A0 (en) 2015-02-26
PT2882770T (pt) 2017-09-11
LT2882770T (lt) 2017-10-10

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/08/2013, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 12A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2845 DE 15-07-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.