BR112014015959A8 - método para o tratamento de um indivíduo em necessidade de um enxerto de célula não singênico ou tecido, método para tratar um indivíduo que precisa de um transplante de célula hematopoiética imatura, método para induzir a tolerância específica do doador em um indivíduo que precisa de uma célula não singênica ou enxerto de tecido, e método para tratar um indivíduo que precisa de uma célula não singênica ou enxerto de tecido - Google Patents
método para o tratamento de um indivíduo em necessidade de um enxerto de célula não singênico ou tecido, método para tratar um indivíduo que precisa de um transplante de célula hematopoiética imatura, método para induzir a tolerância específica do doador em um indivíduo que precisa de uma célula não singênica ou enxerto de tecido, e método para tratar um indivíduo que precisa de uma célula não singênica ou enxerto de tecidoInfo
- Publication number
- BR112014015959A8 BR112014015959A8 BR112014015959A BR112014015959A BR112014015959A8 BR 112014015959 A8 BR112014015959 A8 BR 112014015959A8 BR 112014015959 A BR112014015959 A BR 112014015959A BR 112014015959 A BR112014015959 A BR 112014015959A BR 112014015959 A8 BR112014015959 A8 BR 112014015959A8
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- cell
- treating
- need
- syngeneic
- Prior art date
Links
- 238000000034 method Methods 0.000 title 4
- 210000004027 cell Anatomy 0.000 title 3
- 210000003958 hematopoietic stem cell Anatomy 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 238000002054 transplantation Methods 0.000 title 1
Classifications
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Zoology (AREA)
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- Organic Chemistry (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
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- Nutrition Science (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
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- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161578917P | 2011-12-22 | 2011-12-22 | |
| PCT/IL2012/050541 WO2013093919A2 (en) | 2011-12-22 | 2012-12-20 | A combination therapy for a stable and long term engraftment using specific protocols for t/b cell depletion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014015959A2 BR112014015959A2 (pt) | 2017-06-13 |
| BR112014015959A8 true BR112014015959A8 (pt) | 2017-07-04 |
Family
ID=48669650
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014015959A BR112014015959A8 (pt) | 2011-12-22 | 2012-12-20 | método para o tratamento de um indivíduo em necessidade de um enxerto de célula não singênico ou tecido, método para tratar um indivíduo que precisa de um transplante de célula hematopoiética imatura, método para induzir a tolerância específica do doador em um indivíduo que precisa de uma célula não singênica ou enxerto de tecido, e método para tratar um indivíduo que precisa de uma célula não singênica ou enxerto de tecido |
| BR112014015960A BR112014015960A8 (pt) | 2011-12-22 | 2012-12-20 | método para tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante hematopoiéticas, método para o tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante de células hematopoiéticas imaturas, e método para indução de tolerância do doador específico em um indivíduo em necessidade de um enxerto de célula ou tecido não congênito |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014015960A BR112014015960A8 (pt) | 2011-12-22 | 2012-12-20 | método para tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante hematopoiéticas, método para o tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante de células hematopoiéticas imaturas, e método para indução de tolerância do doador específico em um indivíduo em necessidade de um enxerto de célula ou tecido não congênito |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US10369172B2 (https=) |
| EP (2) | EP2793914B1 (https=) |
| JP (3) | JP2015504047A (https=) |
| KR (2) | KR102109643B1 (https=) |
| CN (2) | CN104470542A (https=) |
| AU (3) | AU2012355989B2 (https=) |
| BR (2) | BR112014015959A8 (https=) |
| CA (2) | CA2859953A1 (https=) |
| DK (2) | DK2797421T3 (https=) |
| ES (2) | ES2811529T3 (https=) |
| IN (2) | IN2014MN01467A (https=) |
| MX (2) | MX370404B (https=) |
| RU (2) | RU2648354C2 (https=) |
| SG (3) | SG11201403459XA (https=) |
| WO (2) | WO2013093920A2 (https=) |
| ZA (2) | ZA201405071B (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012305931B2 (en) | 2011-09-08 | 2017-09-07 | Yeda Research And Development Co. Ltd | Anti third party central memory T cells, methods of producing same and use of same in transplantation and disease treatment |
| KR20140102730A (ko) | 2011-12-08 | 2014-08-22 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 포유류 태아 폐 세포와 이를 치료용으로 사용하는 방법 |
| MX370404B (es) | 2011-12-22 | 2019-12-11 | Yeda Res & Dev | Uso de una terapia de combinación para inducir un injerto estable y a largo plazo. |
| AU2014262532B2 (en) | 2013-05-09 | 2019-08-22 | Advanced Neuroregenerative Therapies, Llc | G-CSF for use in treating or preventing a disease associated with aging in a patient, for administration with a stem-cell containing composition and/or an electromagnetic signal |
| ES2917884T3 (es) | 2015-06-18 | 2022-07-12 | Yeda Res & Dev | Protocolos de acondicionamiento y uso de los mismos para la regeneración de tejidos |
| JP7057748B2 (ja) * | 2015-07-16 | 2022-04-20 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッド | 遺伝子改変された抗第三者中枢性メモリーt細胞および免疫療法におけるその使用 |
| CN115137752A (zh) * | 2015-08-25 | 2022-10-04 | Uab研究基金会 | 用于干细胞移植的方法 |
| MX2018006828A (es) * | 2015-12-04 | 2018-08-09 | Hutchinson Fred Cancer Res | Usos de poblaciones expandidas de celulas madre/progenitoras hematopoyeticas. |
| WO2017203520A1 (en) | 2016-05-22 | 2017-11-30 | Yeda Research And Development Co. Ltd. | Methods of using pulmonary cells for transplantation and induction of tolerance |
| MX2018014991A (es) * | 2016-06-03 | 2019-08-29 | Memorial Sloan Kettering Cancer Center | Terapias adoptivas de celulas como opciones de tratamiento temprano. |
| CN110392736A (zh) | 2017-01-18 | 2019-10-29 | 耶达研究及发展有限公司 | 遗传修饰的反抑细胞及其在免疫治疗中的用途 |
| US10751368B2 (en) | 2017-01-18 | 2020-08-25 | Yeda Research And Development Co. Ltd. | Methods of transplantation and disease treatment |
| MX395639B (es) | 2017-01-20 | 2025-03-25 | Heidelberg Pharma Res Gmbh | Composiciones y métodos para el agotamiento de células cd137+. |
| EP3595683A1 (en) | 2017-03-15 | 2020-01-22 | Orca Biosystems, Inc. | Compositions and methods for hematopoietic stem cell transplants |
| MX2020004811A (es) * | 2017-11-15 | 2020-10-07 | Weird Science Llc | Métodos y composiciones de reconstrucción no mieloablativa de médula ósea. |
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