BR112014015959A8 - método para o tratamento de um indivíduo em necessidade de um enxerto de célula não singênico ou tecido, método para tratar um indivíduo que precisa de um transplante de célula hematopoiética imatura, método para induzir a tolerância específica do doador em um indivíduo que precisa de uma célula não singênica ou enxerto de tecido, e método para tratar um indivíduo que precisa de uma célula não singênica ou enxerto de tecido - Google Patents

método para o tratamento de um indivíduo em necessidade de um enxerto de célula não singênico ou tecido, método para tratar um indivíduo que precisa de um transplante de célula hematopoiética imatura, método para induzir a tolerância específica do doador em um indivíduo que precisa de uma célula não singênica ou enxerto de tecido, e método para tratar um indivíduo que precisa de uma célula não singênica ou enxerto de tecido

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Publication number
BR112014015959A8
BR112014015959A8 BR112014015959A BR112014015959A BR112014015959A8 BR 112014015959 A8 BR112014015959 A8 BR 112014015959A8 BR 112014015959 A BR112014015959 A BR 112014015959A BR 112014015959 A BR112014015959 A BR 112014015959A BR 112014015959 A8 BR112014015959 A8 BR 112014015959A8
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BR
Brazil
Prior art keywords
individual
cell
treating
need
syngeneic
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BR112014015959A
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English (en)
Portuguese (pt)
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BR112014015959A2 (pt
Inventor
Bachar-Lusting Esther
Reisner Yair
Original Assignee
Yeda Res & Dev
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Publication of BR112014015959A2 publication Critical patent/BR112014015959A2/pt
Publication of BR112014015959A8 publication Critical patent/BR112014015959A8/pt

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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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BR112014015959A 2011-12-22 2012-12-20 método para o tratamento de um indivíduo em necessidade de um enxerto de célula não singênico ou tecido, método para tratar um indivíduo que precisa de um transplante de célula hematopoiética imatura, método para induzir a tolerância específica do doador em um indivíduo que precisa de uma célula não singênica ou enxerto de tecido, e método para tratar um indivíduo que precisa de uma célula não singênica ou enxerto de tecido BR112014015959A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161578917P 2011-12-22 2011-12-22
PCT/IL2012/050541 WO2013093919A2 (en) 2011-12-22 2012-12-20 A combination therapy for a stable and long term engraftment using specific protocols for t/b cell depletion

Publications (2)

Publication Number Publication Date
BR112014015959A2 BR112014015959A2 (pt) 2017-06-13
BR112014015959A8 true BR112014015959A8 (pt) 2017-07-04

Family

ID=48669650

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112014015959A BR112014015959A8 (pt) 2011-12-22 2012-12-20 método para o tratamento de um indivíduo em necessidade de um enxerto de célula não singênico ou tecido, método para tratar um indivíduo que precisa de um transplante de célula hematopoiética imatura, método para induzir a tolerância específica do doador em um indivíduo que precisa de uma célula não singênica ou enxerto de tecido, e método para tratar um indivíduo que precisa de uma célula não singênica ou enxerto de tecido
BR112014015960A BR112014015960A8 (pt) 2011-12-22 2012-12-20 método para tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante hematopoiéticas, método para o tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante de células hematopoiéticas imaturas, e método para indução de tolerância do doador específico em um indivíduo em necessidade de um enxerto de célula ou tecido não congênito

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR112014015960A BR112014015960A8 (pt) 2011-12-22 2012-12-20 método para tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante hematopoiéticas, método para o tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante de células hematopoiéticas imaturas, e método para indução de tolerância do doador específico em um indivíduo em necessidade de um enxerto de célula ou tecido não congênito

Country Status (16)

Country Link
US (5) US10369172B2 (https=)
EP (2) EP2793914B1 (https=)
JP (3) JP2015504047A (https=)
KR (2) KR102109643B1 (https=)
CN (2) CN104470542A (https=)
AU (3) AU2012355989B2 (https=)
BR (2) BR112014015959A8 (https=)
CA (2) CA2859953A1 (https=)
DK (2) DK2797421T3 (https=)
ES (2) ES2811529T3 (https=)
IN (2) IN2014MN01467A (https=)
MX (2) MX370404B (https=)
RU (2) RU2648354C2 (https=)
SG (3) SG11201403459XA (https=)
WO (2) WO2013093920A2 (https=)
ZA (2) ZA201405071B (https=)

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AU2012305931B2 (en) 2011-09-08 2017-09-07 Yeda Research And Development Co. Ltd Anti third party central memory T cells, methods of producing same and use of same in transplantation and disease treatment
KR20140102730A (ko) 2011-12-08 2014-08-22 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 포유류 태아 폐 세포와 이를 치료용으로 사용하는 방법
MX370404B (es) 2011-12-22 2019-12-11 Yeda Res & Dev Uso de una terapia de combinación para inducir un injerto estable y a largo plazo.
AU2014262532B2 (en) 2013-05-09 2019-08-22 Advanced Neuroregenerative Therapies, Llc G-CSF for use in treating or preventing a disease associated with aging in a patient, for administration with a stem-cell containing composition and/or an electromagnetic signal
ES2917884T3 (es) 2015-06-18 2022-07-12 Yeda Res & Dev Protocolos de acondicionamiento y uso de los mismos para la regeneración de tejidos
JP7057748B2 (ja) * 2015-07-16 2022-04-20 イェダ リサーチ アンド ディベロップメント カンパニー リミテッド 遺伝子改変された抗第三者中枢性メモリーt細胞および免疫療法におけるその使用
CN115137752A (zh) * 2015-08-25 2022-10-04 Uab研究基金会 用于干细胞移植的方法
MX2018006828A (es) * 2015-12-04 2018-08-09 Hutchinson Fred Cancer Res Usos de poblaciones expandidas de celulas madre/progenitoras hematopoyeticas.
WO2017203520A1 (en) 2016-05-22 2017-11-30 Yeda Research And Development Co. Ltd. Methods of using pulmonary cells for transplantation and induction of tolerance
MX2018014991A (es) * 2016-06-03 2019-08-29 Memorial Sloan Kettering Cancer Center Terapias adoptivas de celulas como opciones de tratamiento temprano.
CN110392736A (zh) 2017-01-18 2019-10-29 耶达研究及发展有限公司 遗传修饰的反抑细胞及其在免疫治疗中的用途
US10751368B2 (en) 2017-01-18 2020-08-25 Yeda Research And Development Co. Ltd. Methods of transplantation and disease treatment
MX395639B (es) 2017-01-20 2025-03-25 Heidelberg Pharma Res Gmbh Composiciones y métodos para el agotamiento de células cd137+.
EP3595683A1 (en) 2017-03-15 2020-01-22 Orca Biosystems, Inc. Compositions and methods for hematopoietic stem cell transplants
MX2020004811A (es) * 2017-11-15 2020-10-07 Weird Science Llc Métodos y composiciones de reconstrucción no mieloablativa de médula ósea.
WO2019108863A1 (en) 2017-11-29 2019-06-06 Magenta Therapeutics, Inc. Compositions and methods for the depletion of cd5+ cells
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