BR112013002832A2 - composição compreendendo retinol, um precursor ou um produto de reação do mesmo e um extrato vegetal de pelo menos uma planta de camomila para o tratamento de câncer - Google Patents

composição compreendendo retinol, um precursor ou um produto de reação do mesmo e um extrato vegetal de pelo menos uma planta de camomila para o tratamento de câncer

Info

Publication number
BR112013002832A2
BR112013002832A2 BR112013002832A BR112013002832A BR112013002832A2 BR 112013002832 A2 BR112013002832 A2 BR 112013002832A2 BR 112013002832 A BR112013002832 A BR 112013002832A BR 112013002832 A BR112013002832 A BR 112013002832A BR 112013002832 A2 BR112013002832 A2 BR 112013002832A2
Authority
BR
Brazil
Prior art keywords
plant
composition
precursor
cancer
chamomile
Prior art date
Application number
BR112013002832A
Other languages
English (en)
Inventor
Jianying Yam
Matthias H Kreuter
Original Assignee
Alpinia Laudanum Inst Of Phytopharmaceutical Sciences Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpinia Laudanum Inst Of Phytopharmaceutical Sciences Ag filed Critical Alpinia Laudanum Inst Of Phytopharmaceutical Sciences Ag
Publication of BR112013002832A2 publication Critical patent/BR112013002832A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

composição compreendendo retinol, um precursor ou um produto de reação do mesmo e um extrato vegetal de pelo menos uma planta de camomila para o tratamento de câncer. a invenção refere-se a (i) vitamina a, um produto de reação, um metabólito ou um precursor da mesma e (ii) extrato vegetal de camomila ou um componente ativo do mesmo, preferencialmente para uso no tratamento de câncer. a composição da invenção pode ser fornecida como um medicamento ou uma composição farmacêutica. pelo menos uma planta de camomila tipicamente contida nas composições da invenção preferencialmente compreende matricaria recutita, mais preferencialmente flores tubiformis de matricaria recutita. ésteres de retinol tipicamente contidos nas composições da invenção tipicamente compreendem, por exemplo, acetato de retinila e um extrrato vegetal da planta matricaria recutita.
BR112013002832A 2010-08-05 2011-08-04 composição compreendendo retinol, um precursor ou um produto de reação do mesmo e um extrato vegetal de pelo menos uma planta de camomila para o tratamento de câncer BR112013002832A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37090110P 2010-08-05 2010-08-05
EP10008189A EP2420228A1 (en) 2010-08-05 2010-08-05 Composition comprising retinol, a precursor or a reaction product of it and a plant extract from at least one chamomilla plant for the treatment of cancer
PCT/EP2011/003923 WO2012016706A1 (en) 2010-08-05 2011-08-04 Composition comprising retinol, a precursor or a reaction product of it and a plant extract from at least one chamomilla plant for the treatment of cancer

Publications (1)

Publication Number Publication Date
BR112013002832A2 true BR112013002832A2 (pt) 2016-05-31

Family

ID=43033084

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013002832A BR112013002832A2 (pt) 2010-08-05 2011-08-04 composição compreendendo retinol, um precursor ou um produto de reação do mesmo e um extrato vegetal de pelo menos uma planta de camomila para o tratamento de câncer

Country Status (11)

Country Link
US (4) US20140234452A1 (pt)
EP (2) EP2420228A1 (pt)
JP (1) JP5636108B2 (pt)
KR (1) KR20130135226A (pt)
CN (1) CN103037855A (pt)
AU (1) AU2011287876A1 (pt)
BR (1) BR112013002832A2 (pt)
CA (1) CA2805075A1 (pt)
RU (1) RU2013109416A (pt)
WO (1) WO2012016706A1 (pt)
ZA (1) ZA201300084B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014085486A2 (en) 2012-11-30 2014-06-05 Waters Technologies Corporation Methods and apparatus for the analysis of vitamin d metabolites
EP3110432A1 (en) * 2014-02-24 2017-01-04 Alpinia Laudanum Institute Of Phytopharmaceutical Sciences AG Compositions for use in the treatment of mucositis and/or stomatitis
US20190040150A1 (en) * 2015-07-31 2019-02-07 Vascular Biogenics Ltd. Motile Sperm Domain Containing Protein 2 and Cancer
EP4138798A1 (en) * 2020-04-20 2023-03-01 Regenall Limited Treatment of pulmonary fibrosis
CA3191242A1 (en) 2020-09-10 2022-03-17 Itzhak Mendel Motile sperm domain containing protein 2 antibodies and methods of use thereof
KR102553872B1 (ko) * 2021-07-21 2023-07-10 전북대학교산학협력단 레티놀산 전구체 및 이를 포함하는 항암제 조성물

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EP0496230A1 (de) 1991-01-23 1992-07-29 ASTA Medica Aktiengesellschaft Herstellung eines Kamillenextraktes mit antimikrobiellen Eigenschaften
DE4136811A1 (de) * 1991-11-08 1993-05-13 Bernd Haertel Mittel zur reinigung der haut
US5620980A (en) 1995-02-22 1997-04-15 Macrochem Corporation Method for treating hair loss
DE19523079A1 (de) * 1995-06-26 1997-01-02 Basf Ag Ester und Amide der 9(Z)-Retinsäure
JPH10203921A (ja) 1997-01-20 1998-08-04 Shiseido Co Ltd 皮膚外用剤
AU2001286578A1 (en) * 2000-08-24 2002-03-04 Tim Ioannides Topical antioxidant having vitamin c and method of combination with topical agent by user
JPWO2002045733A1 (ja) * 2000-12-08 2004-06-10 協和醗酵工業株式会社 鎮痒または抗掻痒活性を有する経口剤
WO2002058640A1 (en) * 2001-01-23 2002-08-01 Harris Dennis H Topical therapeutic skin care system
US20030003166A1 (en) * 2001-04-27 2003-01-02 Goen Group, Inc. Immunity enhancing supplements for lung support
GB0212405D0 (en) 2002-05-29 2002-07-10 Insignion Holdings Ltd Composition and its therapeutic use
WO2004009538A1 (en) * 2002-07-23 2004-01-29 Ardenia Investments Ltd. Retinol derivatives, their use in the treatment of cancer and for potentiating the efficacy of other cytotoxic agents
US7148210B2 (en) 2002-10-15 2006-12-12 Trustees Of Dartmouth College Method of treating bone metastasis
US20050037034A1 (en) * 2003-05-05 2005-02-17 Rhoades Dean L. Method, apparatus, and composition for treating acne
DE50300325D1 (de) * 2003-11-03 2005-03-31 Peter-Hansen Volkmann Vaginalpflegezusammensetzung
US7060306B2 (en) * 2003-11-10 2006-06-13 Springstead Patricia R Skin formulation
US7887851B2 (en) 2004-06-07 2011-02-15 Kao Corporation Aromatase activator
WO2006109898A1 (en) 2005-04-09 2006-10-19 Pion-Tech Co., Ltd Antimicrobial composition containing natural extract, nano silver and natural essential oil
US20080166313A1 (en) * 2005-11-01 2008-07-10 Juice Beauty Compositions for juice-based skin cleansers
GB0523257D0 (en) 2005-11-15 2005-12-21 Veritron Ltd Purification process
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GB0710536D0 (en) * 2007-06-01 2007-07-11 Veritron Ltd Plant extract and its therapeutic use
CN101095706A (zh) * 2007-07-19 2008-01-02 邱日辉 含有枸骨水提取物或枸骨醇提取物的抗肿瘤药物
GB0808974D0 (en) 2008-05-16 2008-06-25 Veritron Ltd Plant extract and its therapeutic use

Also Published As

Publication number Publication date
US20140234452A1 (en) 2014-08-21
RU2013109416A (ru) 2014-09-10
JP2013532700A (ja) 2013-08-19
EP2420228A1 (en) 2012-02-22
KR20130135226A (ko) 2013-12-10
WO2012016706A1 (en) 2012-02-09
JP5636108B2 (ja) 2014-12-03
US20190358281A1 (en) 2019-11-28
ZA201300084B (en) 2013-08-28
US10369180B2 (en) 2019-08-06
US20180117108A1 (en) 2018-05-03
EP2600856B1 (en) 2015-09-16
US10028989B2 (en) 2018-07-24
EP2600856A1 (en) 2013-06-12
CA2805075A1 (en) 2012-02-09
AU2011287876A1 (en) 2013-02-07
US20140037771A1 (en) 2014-02-06
CN103037855A (zh) 2013-04-10

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]