BR102013022698A8 - Éster de poliglicerol, processo para a produção do mesmo, seu uso e formulação cosmética ou farmacêutica - Google Patents

Éster de poliglicerol, processo para a produção do mesmo, seu uso e formulação cosmética ou farmacêutica

Info

Publication number
BR102013022698A8
BR102013022698A8 BR102013022698A BR102013022698A BR102013022698A8 BR 102013022698 A8 BR102013022698 A8 BR 102013022698A8 BR 102013022698 A BR102013022698 A BR 102013022698A BR 102013022698 A BR102013022698 A BR 102013022698A BR 102013022698 A8 BR102013022698 A8 BR 102013022698A8
Authority
BR
Brazil
Prior art keywords
cosmetic
production
pharmaceutical formulation
same
polyglycerol ester
Prior art date
Application number
BR102013022698A
Other languages
English (en)
Other versions
BR102013022698B8 (pt
BR102013022698A2 (pt
BR102013022698B1 (pt
Inventor
Meyer Jürgen
Friedrich Achim
Fötsch Hannelore
Springer Oliver
Marian Von Hof Jan
Henning Wenk Hans
Original Assignee
Evonik Industries Ag
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Industries Ag, Evonik Degussa Gmbh filed Critical Evonik Industries Ag
Publication of BR102013022698A2 publication Critical patent/BR102013022698A2/pt
Publication of BR102013022698A8 publication Critical patent/BR102013022698A8/pt
Publication of BR102013022698B1 publication Critical patent/BR102013022698B1/pt
Publication of BR102013022698B8 publication Critical patent/BR102013022698B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85—Polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/33—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with hydroxy compounds having more than three hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/604—Polycarboxylic acid esters, the acid moiety containing more than two carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C08G65/48—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/34—Higher-molecular-weight carboxylic acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterized by the type of post-polymerisation functionalisation
    • C08G2650/04—End-capping

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polyethers (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

ÉSTERES DE POLIGLICEROL COM DISTRIBUIÇÃO OLIGOMÉRICA PARTICULAR DA POLIGLICERINA, PROCESSO PARA A PRODUÇÃO E USO DOS MESMOS, EMULSIFICANTE CONTENDO ÉSTER DE POLIGLICEROL E FORMULAÇÃO COSMÉTICA OU FARMACÊUTICA A invenção refere-se a novos ésteres de poliglicerol com uma distribuição oligomérica particular da poliglicerina contida, bem com seu uso em formulações especialmente cosméticas como, por exemplo, emulsificante.
BR102013022698A 2012-09-05 2013-09-05 Éster de poliglicerol, processo para a produção do mesmo, seu uso e formulação cosmética ou farmacêutica BR102013022698B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012215707.7A DE102012215707A1 (de) 2012-09-05 2012-09-05 Polyglycerinester mit besonderer Oligomerenverteilung des Polyglycerins
DE102012215707.7 2012-09-05

Publications (4)

Publication Number Publication Date
BR102013022698A2 BR102013022698A2 (pt) 2014-10-21
BR102013022698A8 true BR102013022698A8 (pt) 2017-07-04
BR102013022698B1 BR102013022698B1 (pt) 2020-03-17
BR102013022698B8 BR102013022698B8 (pt) 2022-04-26

Family

ID=48951403

Family Applications (1)

Application Number Title Priority Date Filing Date
BR102013022698A BR102013022698B8 (pt) 2012-09-05 2013-09-05 Éster de poliglicerol, processo para a produção do mesmo, seu uso e formulação cosmética ou farmacêutica

Country Status (6)

Country Link
US (1) US9427385B2 (pt)
EP (1) EP2705832B1 (pt)
JP (1) JP6332928B2 (pt)
CN (1) CN103664593B (pt)
BR (1) BR102013022698B8 (pt)
DE (1) DE102012215707A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012206574A1 (de) * 2012-04-20 2013-10-24 Evonik Industries Ag Verwendung von Polyglycerinpartialestern als Entschäumer
DE102013224957A1 (de) 2013-12-05 2015-06-11 Evonik Industries Ag Polyglycerinpartialester, ihre Herstellung und Verwendung
DE102014203868A1 (de) * 2014-03-04 2015-09-10 Evonik Degussa Gmbh Polyglycerinester mit besonderer Oligomerenverteilung des Polyglycerins
US10292925B2 (en) 2015-03-13 2019-05-21 Evonik Specialty Chemicals (Shanghai) Co., Ltd. Peg free stable low viscosity oil-in-water emulsion and use thereof
JP7009046B2 (ja) * 2015-12-22 2022-01-25 ロレアル 改善されたサンケア組成物
CN105662918B (zh) * 2016-01-15 2021-06-29 天津天狮生物发展有限公司 头皮发根护理精华露及其制备方法
EP3192491B1 (de) * 2016-01-15 2020-01-08 Evonik Operations GmbH Zusammensetzung enthaltend polyglycerinester und hydroxy-alkylmodifiziertes guar
KR102489815B1 (ko) 2016-07-19 2023-01-19 에보니크 오퍼레이션즈 게엠베하 다공성 플라스틱 코팅을 제조하기 위한 폴리올에스테르의 용도
BR112019003247B1 (pt) 2016-08-18 2022-01-25 Evonik Operations Gmbh Ésteres de poliglicerol reticulados, seu método de preparo e uso e preparações cosméticas ou farmacêuticas
JP7265447B2 (ja) * 2019-08-09 2023-04-26 旭化成株式会社 塩化ビニリデン系樹脂フィルム
US11932747B2 (en) 2020-06-24 2024-03-19 Evonik Operations Gmbh Use of long-chain citric acid esters in aqueous polyurethane dispersions
WO2022067402A1 (en) * 2020-09-30 2022-04-07 L'oreal Aqueous gel cosmetic sunscreen composition, process for manufacturing the aqueous gel cosmetic sunscreen composition and the use of the aqueous gel cosmetic sunscreen composition

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003104852A (ja) 2001-09-28 2003-04-09 Lion Corp 毛髪用洗浄剤組成物
DE10316001A1 (de) 2003-04-07 2004-10-21 Goldschmidt Ag Wässrige Formulierungen enthaltend Kombinationen aus anionischen und kationischen Tensiden zur Erzeugung einer Fließgrenze
US7687066B2 (en) * 2003-05-09 2010-03-30 The Nisshin Oillio Group, Ltd. Self emulsifying oily liquid cosmetic
CN100396274C (zh) * 2003-05-09 2008-06-25 日清奥利友集团株式会社 自乳化型油性液体化妆材料
JP2006055029A (ja) 2004-08-18 2006-03-02 Riken Vitamin Co Ltd 農業用樹脂組成物及び農業用資材
DE102005003164A1 (de) 2005-01-21 2006-07-27 Goldschmidt Gmbh Polyglycerinpartialester von Polyricinolsäure und mehrfunktionellen Carbonsäuren und deren Verwendung zur Herstellung von Emulsionen und Dispersionen
DE102005011785A1 (de) 2005-03-11 2006-09-21 Goldschmidt Gmbh Langzeitstabile kosmetische Emulsionen
DE102005051222A1 (de) 2005-10-26 2007-05-03 Goldschmidt Gmbh Flüssige, PEG-freie, kalt verarbeitbare Öl-in-Wasser-Emulgatoren, erhältlich durch Kombination von Emulgatoren auf der Basis von Polyolpartialestern und Säurepartialestern
DE102006004353A1 (de) 2006-01-30 2007-08-02 Goldschmidt Gmbh Kaltherstellbare, niedrigviskose und langzeitstabile kosmetische Emulsionen
JP2008137986A (ja) * 2006-03-09 2008-06-19 Sakamoto Yakuhin Kogyo Co Ltd 化粧品用油剤、及びこれを配合する化粧品
DE102006030532A1 (de) 2006-07-01 2008-01-03 Goldschmidt Gmbh Verfahren zur Verschiebung der Phaseninversionstemperatur von Mikroemulsionen und zur Herstellung feinteiliger Öl-in-Wasser Emulsion
DE102006047247A1 (de) 2006-10-06 2008-04-10 Evonik Goldschmidt Gmbh Kaltherstellbare, niedrigviskose und langzeitstabile kosmetische Emulsionen mit kationische Gruppen enthaltenden Coemulgatoren
CA2665552C (en) 2006-10-13 2013-02-19 Evonik Goldschmidt Gmbh Skin treatment composition
EP2121846B1 (en) * 2007-02-16 2011-10-26 Elevance Renewable Sciences, Inc. Wax compositions and methods of preparing wax compositions
DE102008001788A1 (de) 2008-05-15 2009-11-26 Evonik Goldschmidt Gmbh Verwendung organomodifizierter Siloxanblockcopolymere zur Herstellung kosmetischer oder pharmazeutischer Zusammensetzungen
DE102008042381A1 (de) 2008-09-26 2010-04-01 Evonik Goldschmidt Gmbh Emulgator-Systeme für kosmetische und pharmazeutische Öl-in-Wasser-Emulsionen
JP2010100587A (ja) * 2008-10-27 2010-05-06 Sakamoto Yakuhin Kogyo Co Ltd クレンジングオイル化粧料
JP2010178723A (ja) 2009-02-09 2010-08-19 Sakamoto Yakuhin Kogyo Co Ltd 冷凍パン生地改良剤
DE102009002415A1 (de) 2009-04-16 2010-10-21 Evonik Goldschmidt Gmbh Emulgator enthaltend glycerinmodifizierte Organopolysiloxane
ES2487531T3 (es) 2010-02-12 2014-08-21 Evonik Degussa Gmbh Composición cosmética que contiene éster parcial de poliglicerol
ES2496991T3 (es) * 2010-02-12 2014-09-22 Evonik Degussa Gmbh Composición cosmética que contiene éster parcial de poliglicerol
US8227399B2 (en) 2010-02-12 2012-07-24 Evonik Goldschmidt Gmbh Polyglycerol esters and their use
EP2360140B1 (en) 2010-02-12 2015-09-23 Evonik Degussa GmbH New polyglycerol esters and their use
DE102010002609A1 (de) * 2010-03-05 2011-09-08 Evonik Goldschmidt Gmbh Partialester eines Polyglycerins mit mindestens einer Carbonsäure und einer polyfunktionalen Carbonsäure, ihre Herstellung und Verwendung
DE102010029499A1 (de) 2010-05-31 2011-12-01 Evonik Goldschmidt Gmbh Polyolpartialester zur Anwendung in Kosmetik
FR2973034B1 (fr) * 2011-03-21 2014-05-02 Ard Sa Nouvelles compositions d'oligomeres polyesters et utilisation comme agents tensioactifs

Also Published As

Publication number Publication date
US20140072521A1 (en) 2014-03-13
US9427385B2 (en) 2016-08-30
CN103664593B (zh) 2017-03-01
BR102013022698B8 (pt) 2022-04-26
EP2705832B1 (de) 2019-07-03
JP6332928B2 (ja) 2018-05-30
EP2705832A3 (de) 2015-05-27
EP2705832A2 (de) 2014-03-12
BR102013022698A2 (pt) 2014-10-21
DE102012215707A1 (de) 2014-03-06
CN103664593A (zh) 2014-03-26
BR102013022698B1 (pt) 2020-03-17
JP2014055130A (ja) 2014-03-27

Similar Documents

Publication Publication Date Title
BR102013022698A8 (pt) Éster de poliglicerol, processo para a produção do mesmo, seu uso e formulação cosmética ou farmacêutica
BR112015011933A2 (pt) composições bacterianas sinérgicas e métodos de produção e uso das mesmas
DOP2016000150A (es) Nuevas indazolcarboxamidas, procedimientos para su preparación, preparaciones farmacéuticas que las contienen, así como su uso para la preparación de medicamentos
BR112015011244A2 (pt) Análogos de compstatina de ação prolongada, método de fabricação e uso dos mesmos, bem como composição de qualidade farmacêutica
CR20150386A (es) Composiciones de nanoparticulas de albumina y paclitaxel
CL2015003801A1 (es) Formulaciones de anticuerpos y metodos
CO7240361A2 (es) Composiciones de arni de serpinc1 y métodos de uso de las mismas
EP3878445A3 (en) Acamprosate formulations, methods of using the same, and combinations comprising the same
BR112015028278A2 (pt) processo para a preparação de eritrócitos carregados com uma ou mais substâncias de interesse farmacêutico e eritrócitos assim obtidos
BR112017003346A2 (pt) derivados de pirazolopiridina, seus usos, e composição farmacêutica
BR112014026795A2 (pt) composição cosmética , processo cosmético para tratar a matéria queratínica e uso de uma composição cosmética.
CL2014003325A1 (es) Compuestos derivados de difluoro-hexahidro-ciclopentaoxacinilos y difluoro-hexahidro-benzooxacinilos, inhibidores de bace 1; composicion farmaceutica; y su uso en el tratamiento de enfermedades con niveles elevados de beta-amiloide, tal como la enfermedad de alzheimer
UA113448C2 (xx) Везикули, які містять епідермальний фактор росту і його композиції
CY1121238T1 (el) Παραγωγα παντοθενικου για την αντιμετωπιση νευρολογικων διαταραχων
RS54733B1 (sr) Tritokvalin za upotrebu u tretiranju cistične fibroze
BR112015014885A2 (pt) combinação de agentes ativos, composição cosmética e/ou dermatológica e processo para a preparação de uma composição de agentes ativos.
BR112017013696A2 (pt) peptídeos e seu uso no tratamento de pele
SG11201504381VA (en) Injectable depot formulation comprising optically active tolvaptan and process of producing the same
MX370990B (es) Ésteres de ácidos oligo-hidroxicarboxílicos y uso de los mismos.
BR112015005268A2 (pt) seringa contendo uma composição, em particular farmacêutica, composta por imunoglobulinas, seu método de fabricação e respectivo uso
BR112014029874A8 (pt) composição farmacêutica do tipo emulsão óleo em água, composições e uso da composição farmacêutica
BR112014030949A2 (pt) "composição, processo para o tratamento cosmético e uso de uma composição"
BR112014021326A2 (pt) célula para a expressão de protéina, método para reduzir a atividade de amidação de peptídeo em uma determinada célula, uso de uma célula
CL2015001502A1 (es) Composición farmacéutica que comprende desloratadina y prendnisolona y uso de la misma.
MX364528B (es) Witanólidos útiles para el tratamiento de enfermedades neurodegenerativas.

Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: EVONIK DEGUSSA GMBH (DE)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/09/2013, OBSERVADAS AS CONDICOES LEGAIS.

B16B Notification of grant cancelled [chapter 16.2 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 16.1 NA RPI NO 2567 DE 17/03/2020 POR TER SIDO INDEVIDA.

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/09/2013, OBSERVADAS AS CONDICOES LEGAIS.