BR0016316A - Cristal - Google Patents

Cristal

Info

Publication number
BR0016316A
BR0016316A BR0016316-3A BR0016316A BR0016316A BR 0016316 A BR0016316 A BR 0016316A BR 0016316 A BR0016316 A BR 0016316A BR 0016316 A BR0016316 A BR 0016316A
Authority
BR
Brazil
Prior art keywords
crystal
aspart
sweetness
sweetener
phenylalanine
Prior art date
Application number
BR0016316-3A
Other languages
English (en)
Inventor
Kazutaka Nagashima
Yuuichi Aoki
Eriko Ono
Tadashi Takemoto
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BR0016316A publication Critical patent/BR0016316A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"CRISTAL". Os cristais comercialmente favoráveis de éster 1-metílico de N-[N-[3-(3-hidróxi-4-metoxifenil)propil]-L-<244>-aspartil]-L-fenilalanina , que são úteis como um adoçante com um alto grau de doçura, tendo uma estabilidade alta e uma boa pureza.
BR0016316-3A 1999-12-28 2000-12-25 Cristal BR0016316A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP37325799 1999-12-28
PCT/JP2000/009247 WO2001047949A1 (fr) 1999-12-28 2000-12-25 Cristaux de derives d'aspartame

Publications (1)

Publication Number Publication Date
BR0016316A true BR0016316A (pt) 2002-12-03

Family

ID=18501862

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0016316-3A BR0016316A (pt) 1999-12-28 2000-12-25 Cristal

Country Status (9)

Country Link
US (1) US6818243B2 (pt)
EP (1) EP1245573A1 (pt)
KR (1) KR20020063609A (pt)
CN (1) CN1413218A (pt)
AU (1) AU2225901A (pt)
BR (1) BR0016316A (pt)
CA (1) CA2395948A1 (pt)
RU (1) RU2222544C1 (pt)
WO (1) WO2001047949A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7321800A (en) 1999-10-07 2001-05-10 Ajinomoto Co., Inc. Processes for producing and purifying aspartame derivatives and process for producing production intermediates
DE19962924A1 (de) * 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
DE10129725A1 (de) * 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005045518A1 (de) * 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
DE102005047564A1 (de) * 2005-10-04 2007-05-31 Bayer Healthcare Ag Amorphe Form von 5-Chlor-N-({(5S)2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl)-methyl)-2-thiophencarboxamid
RU2429236C2 (ru) 2005-10-04 2011-09-20 Байер Шеринг Фарма Акциенгезельшафт Новая полиморфная форма и аморфная форма 5-хлор-n-({(5s)-2-оксо-3-[4-(3-оксо-4-морфолинил)-фенил]-1, 3-оксазолидин-5-ил}-метил)-2-тиофенкарбоксамида
DE102006051625A1 (de) * 2006-11-02 2008-05-08 Bayer Materialscience Ag Kombinationstherapie substituierter Oxazolidinone
DE102008028071A1 (de) 2008-06-12 2009-12-17 Bayer Schering Pharma Aktiengesellschaft Neue Cokristall-Verbindung von Rivaroxaban und Malonsäure
WO2013134611A1 (en) 2012-03-09 2013-09-12 Kraft Foods Group Brands Llc Food and beverage products containing 1,3-propanediol and methods of suppressing bitterness and enhancing sweetness in food and beverage products using 1,3-propanediol
EP2822401B1 (en) 2012-03-09 2018-10-31 Kraft Foods Group Brands LLC Oxidized flavor note suppression in comestibles
EA034656B1 (ru) 2014-10-22 2020-03-03 Закляды Фармацеутычне Польфарма С.А Способ получения полиморфа ривароксабана
EP4201933A1 (en) 2021-12-23 2023-06-28 Zaklady Farmaceutyczne Polpharma S.A. Crystallisation process for rivaroxaban

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE145920T1 (de) * 1991-07-19 1996-12-15 Holland Sweetener Co Verfahren zur kristallisation von alpha-l- aspartyl-l-phenylalaninmethylester
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
JPH09249692A (ja) * 1996-03-19 1997-09-22 Holland Sweetener Co Vof α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの晶析方法
JPH1036389A (ja) * 1996-06-27 1998-02-10 Holland Sweetener Co Vof 水溶液からのα−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの晶析方法
ATE386445T1 (de) * 1998-04-09 2008-03-15 Ajinomoto Kk Aspartyldipeptidester-derivate und süssungsmittel
JPH11322788A (ja) * 1998-05-08 1999-11-24 Ajinomoto Co Inc 新規アスパルテーム誘導体結晶及びその製造方法

Also Published As

Publication number Publication date
US6818243B2 (en) 2004-11-16
RU2222544C1 (ru) 2004-01-27
EP1245573A1 (en) 2002-10-02
CA2395948A1 (en) 2001-07-05
WO2001047949A1 (fr) 2001-07-05
WO2001047949A9 (fr) 2001-09-20
CN1413218A (zh) 2003-04-23
AU2225901A (en) 2001-07-09
KR20020063609A (ko) 2002-08-03
RU2002120510A (ru) 2004-01-10
US20030009050A1 (en) 2003-01-09

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1929 DE 26/12/2007 POR TER SIDO INDEVIDO.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1971 DE 14/10/2008.

B15K Others concerning applications: alteration of classification

Ipc: C07K 5/072 (2006.01), A23L 27/30 (2016.01)