BR0010815A - Método de preparação de globulina imune duplamente inativada viralmente para administração intravenosa - Google Patents

Método de preparação de globulina imune duplamente inativada viralmente para administração intravenosa

Info

Publication number
BR0010815A
BR0010815A BR0010815-4A BR0010815A BR0010815A BR 0010815 A BR0010815 A BR 0010815A BR 0010815 A BR0010815 A BR 0010815A BR 0010815 A BR0010815 A BR 0010815A
Authority
BR
Brazil
Prior art keywords
intravenous administration
globulin
immune globulin
gamma
preparing viral
Prior art date
Application number
BR0010815-4A
Other languages
English (en)
Inventor
Raja R Mamidi
Andranik Bagdasarian
Gorgonio Canaveral
Kazuo Takechi
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Publication of BR0010815A publication Critical patent/BR0010815A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"MéTODO DE PREPARAçãO DE GLOBULINA IMUNE DUPLAMENTE INATIVADA VIRALMENTE PARA ADMINISTRAçãO INTRAVENOSA". Um processo para produzir uma solução de gama globulina intravenosamente administrável substancialmente livre de contaminação de virose por fracionamento de uma solução de gama globulina e então tratar a gama globulina purificada, em qualquer ordem, com um solvente - detergente para inativação viral e um tratamento por aquecimento para inativação viral. A seguir, as impurezas desnaturadas, solvente residual e agregado gerado pelo tratamento por aquecimento são removidos da gama-globulina.
BR0010815-4A 1999-05-20 2000-05-17 Método de preparação de globulina imune duplamente inativada viralmente para administração intravenosa BR0010815A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/316,117 US6441144B1 (en) 1999-05-20 1999-05-20 Method for repairing dual virally inactivated immune globulin for intravenous administration
PCT/US2000/008222 WO2000071142A1 (en) 1999-05-20 2000-05-17 Method for preparing dual virally inactivated immune globulin for intravenous administration

Publications (1)

Publication Number Publication Date
BR0010815A true BR0010815A (pt) 2002-06-11

Family

ID=23227544

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010815-4A BR0010815A (pt) 1999-05-20 2000-05-17 Método de preparação de globulina imune duplamente inativada viralmente para administração intravenosa

Country Status (13)

Country Link
US (2) US6441144B1 (pt)
EP (1) EP1183036A4 (pt)
JP (1) JP2003528803A (pt)
KR (1) KR20020019916A (pt)
CN (1) CN1351500A (pt)
AU (1) AU757568B2 (pt)
BR (1) BR0010815A (pt)
CA (1) CA2371356A1 (pt)
CZ (1) CZ20013792A3 (pt)
IL (1) IL146039A0 (pt)
PL (1) PL361133A1 (pt)
WO (1) WO2000071142A1 (pt)
ZA (1) ZA200109516B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995246B1 (en) * 2000-10-19 2006-02-07 Akzo Nobel N.V. Methods for removing suspended particles from soluble protein solutions
ES2184594B1 (es) * 2001-01-17 2004-01-01 Probitas Pharma Sa Procedimiento para la produccion de gammaglobulina g humana inactivada de virus.
ES2357132T3 (es) * 2004-03-19 2011-04-19 Baxter International Inc. Factor ixa para el tratamiento de trastornos hemorrágicos.
TWI391399B (zh) * 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
WO2008100578A2 (en) * 2007-02-14 2008-08-21 Amgen Inc. Method of isolating antibodies by precipitation
PE20090100A1 (es) * 2007-03-30 2009-02-26 Wyeth Corp Metodos de separacion y deteccion de acetato de bacedoxifeno en composiciones farmaceuticas
EP2725035A1 (en) 2007-10-02 2014-04-30 Avaxia Biologics, Inc. Antibody therapy for use in the digestive tract
WO2010059232A1 (en) * 2008-11-20 2010-05-27 Biogen Idec Ma Inc. Arginine inactivation of viruses
US20130116413A1 (en) * 2009-12-29 2013-05-09 Dr. Reddy's Laboratories, Inc. Purification of proteins
SI2734544T1 (sl) 2011-07-18 2021-04-30 The United States Of America as Represente by the Secretary, Department of Health and Human Services, National Institutes Of Health, Office of Technology Transfer Postopki in sestavki za zaviranje patologij, povezanih s poliomavirusom
CN103160486A (zh) * 2013-04-02 2013-06-19 黑龙江迪龙制药有限公司 一种猪凝血酶的制备方法
WO2016209930A1 (en) * 2015-06-24 2016-12-29 The Medical College Of Wisconsin, Inc. System and method for localized processing of quantitative susceptibility maps in magnetic resonance imaging

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801123C2 (de) * 1977-01-26 1986-01-02 Armour Pharma GmbH & Co KG, 3440 Eschwege Verfahren zur Herstellung eines intravenös applizierbaren Serumeiweiß-Präparates
US4820805A (en) 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
JPS6042336A (ja) * 1983-08-18 1985-03-06 Nippon Seiyaku Kk 免疫グロブリンの製造方法
US4835257A (en) 1984-07-07 1989-05-30 Armour Pharma Gmbh Process for preparing gamma globulin suitable for intravenous administration using peg and a citrate buffer
FR2582515B1 (fr) 1985-05-30 1988-11-04 Merieux Inst Procede de preparation de gamma-gobulines administrables par voie intraveineuse et gamma-globulines obtenues
JPH0662436B2 (ja) 1986-05-19 1994-08-17 株式会社ミドリ十字 静注用免疫グロブリン製剤の製造方法
US4841023A (en) 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
CA1310267C (en) 1986-07-09 1992-11-17 Yutaka Hirao Process for heat treating chemically unmodified _-globulin
DE3825429C2 (de) 1988-07-27 1994-02-10 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt
JP2926728B2 (ja) * 1988-12-29 1999-07-28 吉富製薬株式会社 蛋白質含有組成物の製造方法
EP0378208B2 (en) 1989-01-13 2003-01-15 Mitsubishi Pharma Corporation Production method for protein-containing composition
JP2965069B2 (ja) * 1989-01-13 1999-10-18 吉富製薬株式会社 蛋白質含有組成物の製造方法
EP0431129B1 (en) 1989-06-15 1996-05-29 Rorer International (Overseas) Inc. Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions
DE3927111C3 (de) * 1989-08-17 1994-09-01 Biotest Pharma Gmbh Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oderIgA-haltiger Immunglobulinpräparate
US5177194A (en) 1990-02-01 1993-01-05 Baxter International, Inc. Process for purifying immune serum globulins
JP3145696B2 (ja) 1990-10-05 2001-03-12 日本ケミカルリサーチ株式会社 分泌型免疫グロブリンａ製剤の製造法
US5110910A (en) 1991-03-25 1992-05-05 Miles Inc. Virucidal euglobulin precipitation
ES2118386T3 (es) * 1993-02-09 1998-09-16 Octapharma Ag Procedimiento para la inactivacion de virus que no estan provistos de envolventes lipidicas.
WO1998030230A1 (fr) * 1997-01-09 1998-07-16 Yoshitomi Pharmaceutical Industries, Ltd. Compositions proteinees et procede de production

Also Published As

Publication number Publication date
EP1183036A1 (en) 2002-03-06
ZA200109516B (en) 2002-11-06
WO2000071142A1 (en) 2000-11-30
PL361133A1 (en) 2004-09-20
IL146039A0 (en) 2002-07-25
AU4641000A (en) 2000-12-12
EP1183036A4 (en) 2004-12-01
CA2371356A1 (en) 2000-11-30
US6441144B1 (en) 2002-08-27
CN1351500A (zh) 2002-05-29
US20010044524A1 (en) 2001-11-22
CZ20013792A3 (cs) 2002-04-17
KR20020019916A (ko) 2002-03-13
AU757568B2 (en) 2003-02-27
US6504012B2 (en) 2003-01-07
JP2003528803A (ja) 2003-09-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.