BG63274B1 - 14 алфа, 17 алфа-с долу 2-свързани 19-нор-прогестеронови производни - Google Patents

14 алфа, 17 алфа-с долу 2-свързани 19-нор-прогестеронови производни Download PDF

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Publication number
BG63274B1
BG63274B1 BG101554A BG10155497A BG63274B1 BG 63274 B1 BG63274 B1 BG 63274B1 BG 101554 A BG101554 A BG 101554A BG 10155497 A BG10155497 A BG 10155497A BG 63274 B1 BG63274 B1 BG 63274B1
Authority
BG
Bulgaria
Prior art keywords
dione
ethano
methyl
norpregna
diene
Prior art date
Application number
BG101554A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101554A (en
Inventor
Klaus Schoellkopf
Wolfgang Halfbrodt
Joachim Kuhnke
Wolfgang Schwede
Karl-Heinrich Fritzemeier
Rolf Krattenmacher
Hans-Peter Muhn
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG101554A publication Critical patent/BG101554A/xx
Publication of BG63274B1 publication Critical patent/BG63274B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG101554A 1994-12-23 1997-06-03 14 алфа, 17 алфа-с долу 2-свързани 19-нор-прогестеронови производни BG63274B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4447401A DE4447401A1 (de) 1994-12-23 1994-12-23 14,17-C¶2¶-überbrückte Steroide
PCT/EP1995/005107 WO1996020209A2 (de) 1994-12-23 1995-12-23 14α,17α-C2-ÜBERBRÜCKTE 19-NOR-PROGESTERONDERIVATE

Publications (2)

Publication Number Publication Date
BG101554A BG101554A (en) 1998-09-30
BG63274B1 true BG63274B1 (bg) 2001-08-31

Family

ID=6537601

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101554A BG63274B1 (bg) 1994-12-23 1997-06-03 14 алфа, 17 алфа-с долу 2-свързани 19-нор-прогестеронови производни

Country Status (33)

Country Link
US (3) US5827842A (sl)
EP (1) EP0799238B1 (sl)
JP (1) JPH10511379A (sl)
KR (1) KR100400621B1 (sl)
CN (1) CN1109689C (sl)
AR (1) AR002263A1 (sl)
AT (1) ATE193300T1 (sl)
AU (1) AU692346B2 (sl)
BG (1) BG63274B1 (sl)
CA (1) CA2208605C (sl)
CZ (1) CZ292696B6 (sl)
DE (2) DE4447401A1 (sl)
DK (1) DK0799238T3 (sl)
EE (1) EE03356B1 (sl)
ES (1) ES2151612T3 (sl)
FI (1) FI972624A (sl)
GR (1) GR3034261T3 (sl)
HU (1) HUP0600457A2 (sl)
IL (1) IL116504A (sl)
LT (1) LT4295B (sl)
LV (1) LV11954B (sl)
NO (1) NO310198B1 (sl)
NZ (1) NZ298770A (sl)
PL (1) PL182642B1 (sl)
PT (1) PT799238E (sl)
RO (1) RO119366B1 (sl)
RU (1) RU2169153C2 (sl)
SI (1) SI9520137A (sl)
SK (1) SK282281B6 (sl)
TW (1) TW333536B (sl)
UA (1) UA45382C2 (sl)
WO (1) WO1996020209A2 (sl)
ZA (1) ZA9510923B (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060038352A (ko) * 1996-09-03 2006-05-03 더 트러스티스 오브 컬럼비아 유니버시티 인 더 시티 오브 뉴욕 비타민 디 및 스테로이드 유도체들의 합성에 사용되는중간체들
DE19848303A1 (de) * 1998-10-14 2000-04-20 Schering Ag Kombination aus Gestagenen und Zuckern
DE19848305C1 (de) * 1998-10-14 2000-05-25 Schering Ag Verfahren zur Umsetzung von substituierten Propargylalkoholen in Gegenwart von sauren Ionenaustauschern und Zwischenprodukte des Verfahrens
EP1216699A1 (de) * 2000-12-21 2002-06-26 Schering Aktiengesellschaft Transdermalsystem enthaltend ein hochpotentes Gestagen
DE102007063503A1 (de) * 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3628189A1 (de) 1986-08-20 1988-02-25 Schering Ag Oestrogen wirksame mittel und 14,17ss-ethano-14ss-estratriene
DE4326240A1 (de) 1993-08-02 1995-02-09 Schering Ag 15,15-Dialkyl-substituierte Derivate des Estradiols

Also Published As

Publication number Publication date
RU2169153C2 (ru) 2001-06-20
SI9520137A (sl) 1998-02-28
EP0799238B1 (de) 2000-05-24
CZ292696B6 (cs) 2003-11-12
BG101554A (en) 1998-09-30
NO972927D0 (no) 1997-06-23
PL182642B1 (pl) 2002-02-28
NZ298770A (en) 1999-10-28
NO972927L (no) 1997-08-22
AU4433896A (en) 1996-07-19
HUP0600457A2 (en) 2006-08-28
MX9704774A (es) 1997-10-31
DE4447401A1 (de) 1996-07-04
EE03356B1 (et) 2001-02-15
CN1109689C (zh) 2003-05-28
JPH10511379A (ja) 1998-11-04
ATE193300T1 (de) 2000-06-15
ZA9510923B (en) 1996-07-04
US5827842A (en) 1998-10-27
LV11954B (lv) 1998-06-20
LT97106A (en) 1997-10-27
US5973172A (en) 1999-10-26
WO1996020209A2 (de) 1996-07-04
FI972624A0 (fi) 1997-06-18
RO119366B1 (ro) 2004-08-30
PT799238E (pt) 2000-11-30
SK282281B6 (sk) 2002-01-07
CN1171115A (zh) 1998-01-21
IL116504A (en) 2001-11-25
CZ195497A3 (cs) 1998-03-18
LV11954A (lv) 1998-01-20
DE59508403D1 (de) 2000-06-29
KR100400621B1 (ko) 2004-02-05
AU692346B2 (en) 1998-06-04
CA2208605C (en) 2008-07-15
ES2151612T3 (es) 2001-01-01
EP0799238A2 (de) 1997-10-08
US6147065A (en) 2000-11-14
DK0799238T3 (da) 2000-10-09
AR002263A1 (es) 1998-03-11
SK78897A3 (en) 1997-12-10
PL320799A1 (en) 1997-10-27
IL116504A0 (en) 1996-03-31
LT4295B (lt) 1998-02-25
UA45382C2 (uk) 2002-04-15
NO310198B1 (no) 2001-06-05
TW333536B (en) 1998-06-11
WO1996020209A3 (de) 1996-09-06
FI972624A (fi) 1997-06-18
CA2208605A1 (en) 1996-07-04
GR3034261T3 (en) 2000-12-29

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