BG62640B1 - Метод за капсулиране на вещества в дрождени клетки - Google Patents
Метод за капсулиране на вещества в дрождени клетки Download PDFInfo
- Publication number
- BG62640B1 BG62640B1 BG100037A BG10003795A BG62640B1 BG 62640 B1 BG62640 B1 BG 62640B1 BG 100037 A BG100037 A BG 100037A BG 10003795 A BG10003795 A BG 10003795A BG 62640 B1 BG62640 B1 BG 62640B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- substance
- solution
- encapsulated
- yeast cells
- substances
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract description 37
- 210000005253 yeast cell Anatomy 0.000 title claims abstract description 15
- 238000000034 method Methods 0.000 title claims abstract description 14
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 8
- 150000001413 amino acids Chemical class 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 4
- 210000004027 cell Anatomy 0.000 claims description 3
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims description 3
- 229910021529 ammonia Inorganic materials 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 235000021323 fish oil Nutrition 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract description 4
- 239000002775 capsule Substances 0.000 description 13
- 239000000243 solution Substances 0.000 description 13
- 239000002904 solvent Substances 0.000 description 7
- 239000007788 liquid Substances 0.000 description 5
- 239000000047 product Substances 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 238000005538 encapsulation Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- RNFJDJUURJAICM-UHFFFAOYSA-N 2,2,4,4,6,6-hexaphenoxy-1,3,5-triaza-2$l^{5},4$l^{5},6$l^{5}-triphosphacyclohexa-1,3,5-triene Chemical compound N=1P(OC=2C=CC=CC=2)(OC=2C=CC=CC=2)=NP(OC=2C=CC=CC=2)(OC=2C=CC=CC=2)=NP=1(OC=1C=CC=CC=1)OC1=CC=CC=C1 RNFJDJUURJAICM-UHFFFAOYSA-N 0.000 description 2
- 241000237858 Gastropoda Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 235000019441 ethanol Nutrition 0.000 description 2
- 229940013317 fish oils Drugs 0.000 description 2
- 239000003063 flame retardant Substances 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000003094 microcapsule Substances 0.000 description 2
- 239000008188 pellet Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000005956 Metaldehyde Substances 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- 241000282849 Ruminantia Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 210000003165 abomasum Anatomy 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000012272 crop production Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- -1 histidine amino acid Chemical class 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- GKKDCARASOJPNG-UHFFFAOYSA-N metaldehyde Chemical compound CC1OC(C)OC(C)OC(C)O1 GKKDCARASOJPNG-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 210000004767 rumen Anatomy 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2989—Microcapsule with solid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
- Materials For Medical Uses (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939306700A GB9306700D0 (en) | 1993-03-31 | 1993-03-31 | Method for encapsulating substances |
| PCT/GB1994/000667 WO1994022572A1 (en) | 1993-03-31 | 1994-03-30 | Method of encapsulating substances in biocapsules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG100037A BG100037A (bg) | 1996-06-28 |
| BG62640B1 true BG62640B1 (bg) | 2000-04-28 |
Family
ID=10733063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG100037A BG62640B1 (bg) | 1993-03-31 | 1995-09-29 | Метод за капсулиране на вещества в дрождени клетки |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5660769A (cs) |
| EP (1) | EP0691885B1 (cs) |
| JP (1) | JP3506704B2 (cs) |
| KR (1) | KR100322348B1 (cs) |
| AT (1) | ATE166595T1 (cs) |
| AU (1) | AU690103B2 (cs) |
| BG (1) | BG62640B1 (cs) |
| BR (1) | BR9406239A (cs) |
| CA (1) | CA2159624C (cs) |
| CZ (1) | CZ285527B6 (cs) |
| DE (1) | DE69410605T2 (cs) |
| DK (1) | DK0691885T3 (cs) |
| ES (1) | ES2117267T3 (cs) |
| GB (1) | GB9306700D0 (cs) |
| HU (1) | HU217330B (cs) |
| NO (1) | NO307368B1 (cs) |
| NZ (1) | NZ263206A (cs) |
| PL (1) | PL181325B1 (cs) |
| WO (1) | WO1994022572A1 (cs) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1312090B1 (it) * | 1999-04-22 | 2002-04-04 | Ecoser S R L | Microrganismi inattivati comprendenti sostanze solubili e/osolubilizzabili ad attivita' farmacologica e/o sostanze nutrizionali |
| ES2335579T5 (es) | 2001-11-15 | 2021-05-27 | San Ei Gen Ffi Inc | Microcápsulas y composiciones orales que las contienen |
| KR101185755B1 (ko) * | 2004-05-20 | 2012-09-27 | 알베마를 코포레이션 | 펠렛화된 브롬화 음이온성 스티렌계 중합체 및 그의 제조 및 용도 |
| FR2879074B1 (fr) * | 2004-12-15 | 2007-08-03 | Adisseo France Sas Soc Par Act | Granules de principe actif hydrophile |
| FR2879075B1 (fr) * | 2004-12-15 | 2007-01-19 | Adisseo France Sas Soc Par Act | Procede de preparation de granules de principe actif hydrophile par extrusion |
| GB0716719D0 (en) * | 2007-08-29 | 2007-10-10 | Chromatide Ltd | Process for carrying out a chemical reaction |
| CN107811237B (zh) * | 2017-10-26 | 2021-07-02 | 中华全国供销合作总社南京野生植物综合利用研究所 | 一种刺梨vc微胶囊及其制备方法 |
| CN115212184A (zh) * | 2022-08-23 | 2022-10-21 | 怀化学院 | 一种紫苏籽油纳米颗粒及其制备方法和应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US498208A (en) * | 1893-05-23 | James g | ||
| FR2179528A1 (en) * | 1972-04-11 | 1973-11-23 | Serozym Laboratoires | Modification of micro-organisms - by addition of neodymium or magnesium chlorides or onion juice |
| US4001480A (en) * | 1974-08-16 | 1977-01-04 | Swift & Company | Encapsulation process utilizing microorganisms and products produced thereby |
| US4574086A (en) * | 1980-05-16 | 1986-03-04 | Hercules Incorporated | Method for retarding degradation of food colors and flavors |
| ATE18576T1 (de) * | 1981-11-21 | 1986-03-15 | Dunlop Ltd | Verfahren zum einkapseln von substanzen mit hilfe von mikroorganismen, und die hierbei erhaltenen eingekapselten produkte. |
| GB2162147A (en) * | 1984-07-26 | 1986-01-29 | Dunlop Ltd | Encapsulation and encapsulated products |
| JPS6154978A (ja) * | 1984-08-24 | 1986-03-19 | Mitsubishi Paper Mills Ltd | 熱応答性バイオカプセル |
| JPS6188871A (ja) * | 1984-10-04 | 1986-05-07 | Mitsubishi Paper Mills Ltd | 感圧性バイオカプセル |
| US4696863A (en) * | 1984-08-28 | 1987-09-29 | Mitsubishi Paper Mills, Ltd. | Biocapsule |
| JPS62186937A (ja) * | 1986-02-10 | 1987-08-15 | Mitsubishi Paper Mills Ltd | マイクロカプセルの製造方法 |
| US5288632A (en) * | 1986-04-12 | 1994-02-22 | Ad2 Limited | Encapsulation of material in microbial cells |
| JPS62294079A (ja) * | 1986-06-11 | 1987-12-21 | Mitsubishi Paper Mills Ltd | マイクロカプセルの製造方法 |
| JPH0829246B2 (ja) * | 1986-10-01 | 1996-03-27 | 三菱製紙株式会社 | マイクロカプセルの製造方法 |
| US4948586A (en) * | 1987-11-02 | 1990-08-14 | Lim Technology Laboratories, Inc. | Microencapsulated insecticidal pathogens |
| GB8918601D0 (en) * | 1989-08-15 | 1989-09-27 | British Textile Tech | Micro-encapsulation method |
| JPH0732870B2 (ja) * | 1990-04-20 | 1995-04-12 | 三菱製紙株式会社 | マイクロカプセルの製造方法 |
| EP0460945B1 (en) * | 1990-06-05 | 1995-10-11 | Mitsubishi Paper Mills, Ltd. | Process for producing microcapsules |
| JP3034069B2 (ja) * | 1991-04-17 | 2000-04-17 | 三菱製紙株式会社 | マイクロカプセルの製造方法 |
| US5443813A (en) * | 1991-06-06 | 1995-08-22 | Associated Universities, Inc. | Loading and conjugating cavity biostructures |
| JPH0515770A (ja) * | 1991-07-12 | 1993-01-26 | Mitsubishi Paper Mills Ltd | マイクロカプセルの製造方法 |
| JP2978299B2 (ja) * | 1991-10-07 | 1999-11-15 | 麒麟麦酒株式会社 | マイクロカプセルの製造方法 |
| JPH05138010A (ja) * | 1991-11-15 | 1993-06-01 | Mitsubishi Paper Mills Ltd | マイクロカプセルの製造方法 |
| US5496728A (en) * | 1991-12-13 | 1996-03-05 | The Procter & Gamble Company | Encapsulation of liquids in micro-organisms |
-
1993
- 1993-03-31 GB GB939306700A patent/GB9306700D0/en active Pending
-
1994
- 1994-03-30 AT AT94911237T patent/ATE166595T1/de not_active IP Right Cessation
- 1994-03-30 JP JP52182594A patent/JP3506704B2/ja not_active Expired - Fee Related
- 1994-03-30 DK DK94911237T patent/DK0691885T3/da active
- 1994-03-30 WO PCT/GB1994/000667 patent/WO1994022572A1/en not_active Ceased
- 1994-03-30 DE DE69410605T patent/DE69410605T2/de not_active Expired - Fee Related
- 1994-03-30 NZ NZ263206A patent/NZ263206A/en unknown
- 1994-03-30 KR KR1019950704219A patent/KR100322348B1/ko not_active Expired - Fee Related
- 1994-03-30 CZ CZ952455A patent/CZ285527B6/cs not_active IP Right Cessation
- 1994-03-30 US US08/532,643 patent/US5660769A/en not_active Expired - Fee Related
- 1994-03-30 BR BR9406239A patent/BR9406239A/pt not_active IP Right Cessation
- 1994-03-30 PL PL94310890A patent/PL181325B1/pl not_active IP Right Cessation
- 1994-03-30 EP EP94911237A patent/EP0691885B1/en not_active Expired - Lifetime
- 1994-03-30 CA CA002159624A patent/CA2159624C/en not_active Expired - Fee Related
- 1994-03-30 ES ES94911237T patent/ES2117267T3/es not_active Expired - Lifetime
- 1994-03-30 HU HU9502855A patent/HU217330B/hu not_active IP Right Cessation
- 1994-03-30 AU AU63806/94A patent/AU690103B2/en not_active Ceased
-
1995
- 1995-09-29 NO NO953897A patent/NO307368B1/no not_active IP Right Cessation
- 1995-09-29 BG BG100037A patent/BG62640B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08508204A (ja) | 1996-09-03 |
| BG100037A (bg) | 1996-06-28 |
| DE69410605D1 (de) | 1998-07-02 |
| KR100322348B1 (ko) | 2002-05-13 |
| NO953897D0 (no) | 1995-09-29 |
| EP0691885A1 (en) | 1996-01-17 |
| BR9406239A (pt) | 1996-01-09 |
| HUT71909A (en) | 1996-02-28 |
| HU217330B (hu) | 1999-12-28 |
| WO1994022572A1 (en) | 1994-10-13 |
| US5660769A (en) | 1997-08-26 |
| AU690103B2 (en) | 1998-04-23 |
| AU6380694A (en) | 1994-10-24 |
| PL310890A1 (en) | 1996-01-08 |
| JP3506704B2 (ja) | 2004-03-15 |
| CA2159624C (en) | 2004-05-25 |
| DE69410605T2 (de) | 1998-09-24 |
| NO953897L (no) | 1995-09-29 |
| EP0691885B1 (en) | 1998-05-27 |
| ES2117267T3 (es) | 1998-08-01 |
| HU9502855D0 (en) | 1995-11-28 |
| NO307368B1 (no) | 2000-03-27 |
| CZ245595A3 (en) | 1996-04-17 |
| NZ263206A (en) | 1997-12-19 |
| KR960701694A (ko) | 1996-03-28 |
| PL181325B1 (pl) | 2001-07-31 |
| GB9306700D0 (en) | 1993-05-26 |
| CZ285527B6 (cs) | 1999-08-11 |
| CA2159624A1 (en) | 1994-10-13 |
| ATE166595T1 (de) | 1998-06-15 |
| DK0691885T3 (da) | 1998-10-12 |
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