BG62258B1 - Нова кристална модификация на cdch, метод за получаването муи фармацевтични препарати, които го съдържат - Google Patents

Нова кристална модификация на cdch, метод за получаването муи фармацевтични препарати, които го съдържат Download PDF

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Publication number
BG62258B1
BG62258B1 BG101043A BG10104396A BG62258B1 BG 62258 B1 BG62258 B1 BG 62258B1 BG 101043 A BG101043 A BG 101043A BG 10104396 A BG10104396 A BG 10104396A BG 62258 B1 BG62258 B1 BG 62258B1
Authority
BG
Bulgaria
Prior art keywords
cdch
monohydrate
water
anhydrous
preparation
Prior art date
Application number
BG101043A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101043A (en
Inventor
Alfons Grunenberg
Patrick Bosche
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG62258(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG101043A publication Critical patent/BG101043A/xx
Publication of BG62258B1 publication Critical patent/BG62258B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG101043A 1995-12-12 1996-12-10 Нова кристална модификация на cdch, метод за получаването муи фармацевтични препарати, които го съдържат BG62258B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
BG101043A BG101043A (en) 1998-04-30
BG62258B1 true BG62258B1 (bg) 1999-06-30

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101043A BG62258B1 (bg) 1995-12-12 1996-12-10 Нова кристална модификация на cdch, метод за получаването муи фармацевтични препарати, които го съдържат

Country Status (42)

Country Link
US (1) US5849752A (enEXAMPLES)
EP (1) EP0780390B1 (enEXAMPLES)
JP (1) JP4104687B2 (enEXAMPLES)
KR (1) KR100525146B1 (enEXAMPLES)
CN (1) CN1061348C (enEXAMPLES)
AR (1) AR005009A1 (enEXAMPLES)
AT (1) ATE221531T1 (enEXAMPLES)
AU (1) AU708006B2 (enEXAMPLES)
BG (1) BG62258B1 (enEXAMPLES)
BR (1) BR9605968A (enEXAMPLES)
CA (1) CA2192418C (enEXAMPLES)
CO (1) CO4480105A1 (enEXAMPLES)
CU (1) CU22774A3 (enEXAMPLES)
CZ (1) CZ288657B6 (enEXAMPLES)
DE (2) DE19546249A1 (enEXAMPLES)
DK (1) DK0780390T3 (enEXAMPLES)
EE (1) EE03474B1 (enEXAMPLES)
ES (1) ES2179910T3 (enEXAMPLES)
HR (1) HRP960558B1 (enEXAMPLES)
HU (1) HU226521B1 (enEXAMPLES)
ID (1) ID22625A (enEXAMPLES)
IL (1) IL119795A (enEXAMPLES)
IN (1) IN185805B (enEXAMPLES)
MA (1) MA24342A1 (enEXAMPLES)
MY (1) MY117492A (enEXAMPLES)
NL (1) NL300109I1 (enEXAMPLES)
NO (1) NO306725B1 (enEXAMPLES)
NZ (1) NZ299905A (enEXAMPLES)
PL (1) PL184885B1 (enEXAMPLES)
PT (1) PT780390E (enEXAMPLES)
RO (1) RO119782B1 (enEXAMPLES)
RU (1) RU2162468C2 (enEXAMPLES)
SA (1) SA96170492B1 (enEXAMPLES)
SG (1) SG47201A1 (enEXAMPLES)
SI (1) SI0780390T1 (enEXAMPLES)
SK (1) SK282805B6 (enEXAMPLES)
SV (1) SV1996000109A (enEXAMPLES)
TR (1) TR199600970A2 (enEXAMPLES)
TW (1) TW411340B (enEXAMPLES)
UA (1) UA35638C2 (enEXAMPLES)
YU (1) YU49485B (enEXAMPLES)
ZA (1) ZA9610405B (enEXAMPLES)

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DE19751948A1 (de) 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
WO2000027398A1 (de) 1998-11-10 2000-05-18 Bayer Aktiengesellschaft Pharmazeutische zubereitung von moxifloxacin
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
WO2004039804A1 (en) * 2002-10-31 2004-05-13 Ranbaxy Laboratories Limited Amorphous moxifloxacin hydrochloride
CA2521398C (en) * 2003-04-09 2011-03-22 Dr. Reddy's Laboratories Limited A crystalline form iii of anhydrous moxifloxacin hydrochloride and a process for preparation thereof
EP1651630A1 (en) * 2003-08-05 2006-05-03 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
WO2005054240A1 (en) * 2003-11-20 2005-06-16 Chemi Spa Polymorphs of 1-cyclopropyl-7-([s,s]-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
SI2032521T1 (sl) 2006-06-27 2010-02-26 Sandoz Ag Nov postopek za pripravo soli
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
AU2007320997B2 (en) * 2006-11-13 2012-11-08 Cipla Limited Process for the synthesis of moxifloxacin hydrochloride
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
BRPI0823092A2 (pt) * 2008-10-09 2015-09-29 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi método de granulação úmida de moxifloxacin anídrico ou seus sais
EP2342204A1 (en) * 2008-11-06 2011-07-13 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
ES2467105T5 (es) 2008-12-08 2017-12-05 Ratiopharm Gmbh Moxifloxacino compactado
NZ596492A (en) 2009-05-15 2013-08-30 Redx Pharma Ltd Redox drug derivatives
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
US9388178B2 (en) 2012-12-04 2016-07-12 Mankind Research Centre Process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
US12036219B2 (en) 2013-03-15 2024-07-16 Melinta Subsidiary Corp. Methods of treating infections in overweight and obese patients using antibiotics

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DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
CN1019114B (zh) * 1986-03-31 1992-11-18 三共株式会社 喹啉-3-羟酸衍生物的制备方法
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
TW209865B (enEXAMPLES) 1992-01-10 1993-07-21 Bayer Ag
ES2167329T3 (es) * 1992-01-31 2002-05-16 Chugai Pharmaceutical Co Ltd Cristal de hidrato de derivado de acido quinolonacarboxilico.
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
NO301165B1 (no) * 1992-12-25 1997-09-22 Daiichi Seiyaku Co Bicykliske aminderivater og antibakterielle midler inneholdende disse
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
EP0676199B1 (en) * 1994-04-07 1998-09-02 Pfizer Inc. Use of trovafloxacin or derivatives thereof for the manufacture of a medicament for the treatment of H. pylori infections

Also Published As

Publication number Publication date
MA24342A1 (fr) 1998-07-01
CN1160052A (zh) 1997-09-24
HU9603428D0 (en) 1997-01-28
KR970042550A (ko) 1997-07-24
JPH09169757A (ja) 1997-06-30
SV1996000109A (es) 1997-10-23
NL300109I1 (nl) 2003-02-03
ZA9610405B (en) 1997-06-23
JP4104687B2 (ja) 2008-06-18
NO965298D0 (no) 1996-12-11
PL184885B1 (pl) 2003-01-31
PT780390E (pt) 2002-11-29
SA96170492B1 (ar) 2006-05-23
CU22774A3 (es) 2002-07-24
MX9606325A (es) 1997-10-31
NO965298L (no) 1997-06-13
SG47201A1 (en) 1998-03-20
EP0780390B1 (de) 2002-07-31
EP0780390A1 (de) 1997-06-25
MY117492A (en) 2004-07-31
RO119782B1 (ro) 2005-03-30
AU708006B2 (en) 1999-07-29
EE03474B1 (et) 2001-08-15
TR199600970A2 (tr) 1997-06-21
HRP960558A2 (en) 1998-02-28
HU226521B1 (en) 2009-03-30
RU2162468C2 (ru) 2001-01-27
IL119795A (en) 1998-12-27
YU49485B (sh) 2006-08-17
PL317415A1 (en) 1997-06-23
US5849752A (en) 1998-12-15
KR100525146B1 (ko) 2006-01-27
CZ288657B6 (cs) 2001-08-15
NO306725B1 (no) 1999-12-13
BG101043A (en) 1998-04-30
SI0780390T1 (en) 2002-10-31
HUP9603428A2 (en) 1997-08-28
AU7421696A (en) 1997-06-19
SK159196A3 (en) 1997-10-08
YU65096A (sh) 1998-12-23
UA35638C2 (uk) 2001-04-16
NZ299905A (en) 1998-09-24
DE59609501D1 (de) 2002-09-05
DK0780390T3 (da) 2002-11-11
HUP9603428A3 (en) 1997-10-28
HRP960558B1 (en) 2002-04-30
CN1061348C (zh) 2001-01-31
DE19546249A1 (de) 1997-06-19
CO4480105A1 (es) 1997-07-09
EE9600201A (et) 1997-06-16
ATE221531T1 (de) 2002-08-15
IL119795A0 (en) 1997-03-18
CA2192418A1 (en) 1997-06-13
CZ364696A3 (en) 1997-07-16
IN185805B (enEXAMPLES) 2001-05-05
SK282805B6 (sk) 2002-12-03
BR9605968A (pt) 1998-08-18
AR005009A1 (es) 1999-04-07
TW411340B (en) 2000-11-11
ID22625A (id) 1999-12-02
ES2179910T3 (es) 2003-02-01
CA2192418C (en) 2001-06-12

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