BG24813A4 - Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли - Google Patents

Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли

Info

Publication number
BG24813A4
BG24813A4 BG030537A BG3053775A BG24813A4 BG 24813 A4 BG24813 A4 BG 24813A4 BG 030537 A BG030537 A BG 030537A BG 3053775 A BG3053775 A BG 3053775A BG 24813 A4 BG24813 A4 BG 24813A4
Authority
BG
Bulgaria
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
salts
preparation
Prior art date
Application number
BG030537A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG24813A4 publication Critical patent/BG24813A4/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG030537A 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли BG24813A4 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
BG24813A4 true BG24813A4 (bg) 1978-05-12

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
BG030537A BG24813A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли
BG029183A BG25087A3 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG029183A BG25087A3 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Country Status (25)

Country Link
JP (1) JPS5827275B2 (enrdf_load_stackoverflow)
AT (1) AT344332B (enrdf_load_stackoverflow)
BE (1) BE826440A (enrdf_load_stackoverflow)
BG (3) BG24813A4 (enrdf_load_stackoverflow)
CA (1) CA1049511A (enrdf_load_stackoverflow)
CH (8) CH612425A5 (enrdf_load_stackoverflow)
CS (1) CS188221B2 (enrdf_load_stackoverflow)
DD (1) DD119236A5 (enrdf_load_stackoverflow)
DE (1) DE2411382C3 (enrdf_load_stackoverflow)
DK (1) DK137188C (enrdf_load_stackoverflow)
ES (6) ES440348A1 (enrdf_load_stackoverflow)
FI (1) FI63571C (enrdf_load_stackoverflow)
FR (1) FR2262984B1 (enrdf_load_stackoverflow)
GB (1) GB1496418A (enrdf_load_stackoverflow)
HU (1) HU177408B (enrdf_load_stackoverflow)
IE (1) IE40945B1 (enrdf_load_stackoverflow)
IL (1) IL46760A (enrdf_load_stackoverflow)
NL (1) NL7502724A (enrdf_load_stackoverflow)
NO (1) NO141800C (enrdf_load_stackoverflow)
PH (1) PH14127A (enrdf_load_stackoverflow)
PL (3) PL93499B1 (enrdf_load_stackoverflow)
RO (2) RO70051A (enrdf_load_stackoverflow)
SE (1) SE421919B (enrdf_load_stackoverflow)
SU (3) SU577982A3 (enrdf_load_stackoverflow)
ZA (1) ZA751394B (enrdf_load_stackoverflow)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
ATE202076T1 (de) * 1995-03-10 2001-06-15 Photocure Asa Ester der 5-aminolevulinsäure als mittel zur photosensibilisierung in der chemotherapie
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ATE554078T1 (de) 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern
US8859580B2 (en) 2007-11-16 2014-10-14 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001059A1 (es) 2008-05-01 2010-11-12 Boehringer Ingelheim Int Compuestos derivados de 1,3-oxazin-2-ona-3,6 sustituidos, inhibidores de la actividad de la 11-beta-hidroxiesteroide deshidrogenasa i; composicion farmaceutica que los comprende; utiles en el tratamiento de enfermedades tales como diabetes mellitus, entre otras.
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
EP2324017B1 (en) 2008-07-25 2014-12-31 Boehringer Ingelheim International GmbH INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
EP2687525B1 (en) 2008-07-25 2015-09-23 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
HU177408B (en) 1981-10-28
SU588916A3 (ru) 1978-01-15
FI63571B (fi) 1983-03-31
SE421919B (sv) 1982-02-08
NO141800C (no) 1980-06-04
ES440346A1 (es) 1977-03-01
ES440348A1 (es) 1977-06-01
CA1049511A (en) 1979-02-27
SE7502592L (enrdf_load_stackoverflow) 1975-09-10
PL93499B1 (enrdf_load_stackoverflow) 1977-05-30
JPS50123675A (enrdf_load_stackoverflow) 1975-09-29
FR2262984B1 (enrdf_load_stackoverflow) 1978-07-28
CH622016A5 (en) 1981-03-13
FR2262984A1 (enrdf_load_stackoverflow) 1975-10-03
NO750773L (enrdf_load_stackoverflow) 1975-09-10
SU577982A3 (ru) 1977-10-25
CH620439A5 (en) 1980-11-28
PL93699B1 (enrdf_load_stackoverflow) 1977-06-30
NO141800B (no) 1980-02-04
DE2411382B2 (de) 1979-01-18
CH620681A5 (en) 1980-12-15
CH612425A5 (en) 1979-07-31
ES440347A1 (es) 1977-06-01
AT344332B (de) 1978-07-10
CH622017A5 (en) 1981-03-13
BG25087A3 (bg) 1978-07-12
RO70051A (ro) 1980-12-30
DK137188C (da) 1978-07-03
FI63571C (fi) 1983-07-11
CS188221B2 (en) 1979-02-28
IL46760A0 (en) 1975-05-22
JPS5827275B2 (ja) 1983-06-08
BG24814A4 (bg) 1978-05-12
CH622015A5 (en) 1981-03-13
IE40945B1 (en) 1979-09-12
PL93700B1 (enrdf_load_stackoverflow) 1977-06-30
CH622014A5 (en) 1981-03-13
DE2411382A1 (de) 1975-09-18
ZA751394B (en) 1976-11-24
NL7502724A (nl) 1975-09-11
IL46760A (en) 1978-12-17
GB1496418A (en) 1977-12-30
ATA153875A (de) 1977-11-15
ES440349A1 (es) 1977-03-01
AU7894275A (en) 1976-09-16
ES440350A1 (es) 1977-03-16
DE2411382C3 (de) 1979-09-06
SU577983A3 (ru) 1977-10-25
DK92975A (enrdf_load_stackoverflow) 1975-09-10
CH620440A5 (en) 1980-11-28
ES440345A1 (es) 1977-03-01
FI750652A7 (enrdf_load_stackoverflow) 1975-09-10
RO69617A (ro) 1980-08-15
PH14127A (en) 1981-02-26
BE826440A (fr) 1975-09-08
IE40945L (en) 1975-09-09
DK137188B (da) 1978-01-30
DD119236A5 (enrdf_load_stackoverflow) 1976-04-12

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