BG106193A - Използване на антитела срещу cd20 за лечение на заболявания при трансплантации - Google Patents

Използване на антитела срещу cd20 за лечение на заболявания при трансплантации Download PDF

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Publication number
BG106193A
BG106193A BG106193A BG10619301A BG106193A BG 106193 A BG106193 A BG 106193A BG 106193 A BG106193 A BG 106193A BG 10619301 A BG10619301 A BG 10619301A BG 106193 A BG106193 A BG 106193A
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BG
Bulgaria
Prior art keywords
lymphocytes
human
antigen
cells
antibodies against
Prior art date
Application number
BG106193A
Other languages
Bulgarian (bg)
English (en)
Inventor
Josee Golay
Martino Introna
Alessandro Rambaldi
Andrea Biondi
Original Assignee
Consiglio Nazionale Delle Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Delle Ricerche filed Critical Consiglio Nazionale Delle Ricerche
Publication of BG106193A publication Critical patent/BG106193A/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
BG106193A 1999-06-11 2001-12-07 Използване на антитела срещу cd20 за лечение на заболявания при трансплантации BG106193A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001299A ITMI991299A1 (it) 1999-06-11 1999-06-11 Uso di anticorpi contro antigeni di superficie per il trattamento della malattia trapianto contro ospite
PCT/EP2000/005212 WO2000076542A1 (fr) 1999-06-11 2000-06-07 Utilisation d'anticorps contre cd20 pour traiter la maladie de rejet du greffon

Publications (1)

Publication Number Publication Date
BG106193A true BG106193A (bg) 2002-08-30

Family

ID=11383150

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106193A BG106193A (bg) 1999-06-11 2001-12-07 Използване на антитела срещу cd20 за лечение на заболявания при трансплантации

Country Status (26)

Country Link
US (1) US20070014785A1 (fr)
EP (1) EP1185299B1 (fr)
JP (1) JP2003501482A (fr)
KR (1) KR20020026455A (fr)
CN (1) CN1253208C (fr)
AU (1) AU774206B2 (fr)
BG (1) BG106193A (fr)
CA (1) CA2376288A1 (fr)
CZ (1) CZ20014450A3 (fr)
DE (1) DE60033030T2 (fr)
DK (1) DK1185299T3 (fr)
EE (1) EE200100667A (fr)
ES (1) ES2278616T3 (fr)
HK (1) HK1043549B (fr)
HU (1) HUP0201600A3 (fr)
IL (1) IL146934A0 (fr)
IS (1) IS6195A (fr)
IT (1) ITMI991299A1 (fr)
NO (1) NO20016035L (fr)
NZ (1) NZ515992A (fr)
PL (1) PL352860A1 (fr)
PT (1) PT1185299E (fr)
SK (1) SK18132001A3 (fr)
TR (1) TR200103581T2 (fr)
WO (1) WO2000076542A1 (fr)
ZA (1) ZA200110004B (fr)

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BRPI0514068B8 (pt) 2004-08-04 2021-05-25 Applied Molecular Evolution Inc anticorpo anti-cd20, e, composição farmacêutica
BRPI0613259A2 (pt) 2005-05-20 2010-12-28 Genentech Inc método de tratamento de amostra biológica e kit de diagnóstico
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KR20080047540A (ko) 2005-07-25 2008-05-29 트루비온 파마슈티칼스, 인코포레이티드 Ｃｄ20 특이적 결합 분자의 단회 투여 용도
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CN101008291B (zh) * 2006-01-26 2010-05-12 金海产品有限公司 用于水池清洁机的密封盒装置
SG172698A1 (en) 2006-06-12 2011-07-28 Trubion Pharmaceuticals Inc Single-chain multivalent binding proteins with effector function
CA2584494A1 (fr) * 2007-03-27 2008-09-27 Jeffrey A. Medin Vecteur codant un polypeptide therapeutique et elements de securite permettant de verifier les cellules transduites
KR101432191B1 (ko) * 2007-06-22 2014-08-20 훗카이도 코리츠 다이가쿠 호진 삿포르 이카 다이가쿠 이식편대숙주 질환의 검출 또는 치료 방법
SI2586788T1 (en) 2007-07-09 2018-07-31 Genentech, Inc. Prevention of the reduction of the disulfide bond during the recombinant production of polypeptides
AU2008282152B2 (en) 2007-07-31 2013-12-19 Regeneron Pharmaceuticals, Inc. Human antibodies to human CD20 and method of using thereof
CA2701329C (fr) 2007-10-16 2017-08-22 Zymogenetics, Inc. Combinaison d'agents d'inhibition de blys et d'agents anti-cd 20 pour le traitement d'une maladie auto-immune
EP2077281A1 (fr) 2008-01-02 2009-07-08 Bergen Teknologioverforing AS Anticorps anti-CD20 ou fragments correspondants pour le traitement de syndrome de fatigue chronique
WO2009114942A1 (fr) 2008-03-20 2009-09-24 University Health Network Fusions de thymidylate kinase et leurs utilisations
SI2132228T1 (sl) 2008-04-11 2011-10-28 Emergent Product Dev Seatle CD37 imunoterapevtik in kombinacija z njegovim bifunkcionalnim kemoterapevtikom
TW201438738A (zh) 2008-09-16 2014-10-16 Genentech Inc 治療進展型多發性硬化症之方法
WO2010075249A2 (fr) 2008-12-22 2010-07-01 Genentech, Inc. Méthode de traitement de la polyarthrite rhumatoïde avec des antagonistes de cellules b
WO2011019619A1 (fr) 2009-08-11 2011-02-17 Genentech, Inc. Production de protéines dans des milieux de culture cellulaire sans glutamine
US9173961B2 (en) 2010-02-10 2015-11-03 Immunogen, Inc. CD20 antibodies and uses thereof
JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
TWI701042B (zh) 2014-03-19 2020-08-11 美商再生元醫藥公司 用於腫瘤治療之方法及抗體組成物
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KR20180053322A (ko) 2015-09-21 2018-05-21 압테보 리서치 앤드 디벨롭먼트 엘엘씨 Cd3 결합 폴리펩타이드
MA43023A (fr) 2015-10-02 2018-08-08 Hoffmann La Roche Anticorps de récepteur de la transferrine humaine/anti-humaine cd20 bispécifique et leurs procédés d'utilisation
AR106189A1 (es) 2015-10-02 2017-12-20 Hoffmann La Roche ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
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Also Published As

Publication number Publication date
PT1185299E (pt) 2007-03-30
KR20020026455A (ko) 2002-04-10
US20070014785A1 (en) 2007-01-18
AU5530300A (en) 2001-01-02
CZ20014450A3 (cs) 2002-04-17
HUP0201600A3 (en) 2005-04-28
CN1253208C (zh) 2006-04-26
ZA200110004B (en) 2003-02-26
DK1185299T3 (da) 2007-05-21
ES2278616T3 (es) 2007-08-16
EP1185299A1 (fr) 2002-03-13
DE60033030T2 (de) 2007-05-31
WO2000076542A1 (fr) 2000-12-21
HK1043549A1 (en) 2002-09-20
NO20016035D0 (no) 2001-12-10
JP2003501482A (ja) 2003-01-14
CN1355712A (zh) 2002-06-26
AU774206B2 (en) 2004-06-17
NZ515992A (en) 2004-01-30
NO20016035L (no) 2002-02-11
HK1043549B (zh) 2006-09-01
ITMI991299A0 (it) 1999-06-11
EE200100667A (et) 2003-02-17
EP1185299B1 (fr) 2007-01-17
IL146934A0 (en) 2002-08-14
IS6195A (is) 2001-12-10
PL352860A1 (en) 2003-09-08
HUP0201600A2 (en) 2002-08-28
CA2376288A1 (fr) 2000-12-21
DE60033030D1 (de) 2007-03-08
ITMI991299A1 (it) 2000-12-11
TR200103581T2 (tr) 2002-08-21
SK18132001A3 (sk) 2002-05-09

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