BG103013A - N-[4-(хетероарилметил)фенил]-хетероариламини - Google Patents
N-[4-(хетероарилметил)фенил]-хетероариламиниInfo
- Publication number
- BG103013A BG103013A BG103013A BG10301398A BG103013A BG 103013 A BG103013 A BG 103013A BG 103013 A BG103013 A BG 103013A BG 10301398 A BG10301398 A BG 10301398A BG 103013 A BG103013 A BG 103013A
- Authority
- BG
- Bulgaria
- Prior art keywords
- optionally substituted
- aryl
- compounds
- alkyl
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретението се отнася до съединения с формула, в която R1 е водород, хидрокси, С1-6 алкил или арил; R2 е водород, по избор заместен С1-6 алкил или арил; Het е по избор заместен ненаситен хетероцикъл, избран между имидазолил, триазолил, тетразолил и пиридинил; формулата означава по избор заместен ненаситен моно- или бицикличенхетероцикъл; и арил е по избор заместен фенил. Изобретението се отнасяи до N-оксиди, до фармацевтично приемливи присъединителни соли на посочените съединения и техните стереохимични изомерни форми, до методи за получаването на съединенията и до състави, които ги съдържат, а така също и до използването им като лекарствени средства.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96201781 | 1996-06-27 | ||
| PCT/EP1997/003248 WO1997049704A1 (en) | 1996-06-27 | 1997-06-19 | N-[4-(heteroarylmethyl)phenyl]-heteroarylamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG103013A true BG103013A (bg) | 1999-09-30 |
| BG63545B1 BG63545B1 (bg) | 2002-04-30 |
Family
ID=8224119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103013A BG63545B1 (bg) | 1996-06-27 | 1998-12-14 | N-[4-(хетероарилметил)фенил]-хетероариламини |
Country Status (33)
| Country | Link |
|---|---|
| US (5) | US6124330A (bg) |
| EP (1) | EP0907650B1 (bg) |
| JP (1) | JP3404749B2 (bg) |
| KR (1) | KR100365312B1 (bg) |
| CN (1) | CN1102593C (bg) |
| AR (1) | AR007626A1 (bg) |
| AT (1) | ATE229019T1 (bg) |
| AU (1) | AU711575B2 (bg) |
| BG (1) | BG63545B1 (bg) |
| BR (1) | BR9710002A (bg) |
| CA (1) | CA2258165C (bg) |
| CZ (1) | CZ297769B6 (bg) |
| DE (1) | DE69717627T2 (bg) |
| DK (1) | DK0907650T3 (bg) |
| EE (1) | EE03688B1 (bg) |
| ES (1) | ES2188957T3 (bg) |
| HK (1) | HK1018458A1 (bg) |
| HU (1) | HU223093B1 (bg) |
| ID (1) | ID17275A (bg) |
| IL (1) | IL127740A (bg) |
| MY (1) | MY116917A (bg) |
| NO (1) | NO312102B1 (bg) |
| NZ (1) | NZ333382A (bg) |
| PL (1) | PL201704B1 (bg) |
| PT (1) | PT907650E (bg) |
| RU (1) | RU2190611C2 (bg) |
| SI (1) | SI0907650T1 (bg) |
| SK (1) | SK282769B6 (bg) |
| TR (1) | TR199802709T2 (bg) |
| TW (1) | TW490464B (bg) |
| UA (1) | UA53649C2 (bg) |
| WO (1) | WO1997049704A1 (bg) |
| ZA (1) | ZA975698B (bg) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU711575B2 (en) | 1996-06-27 | 1999-10-14 | Janssen Pharmaceutica N.V. | N-(4-(Heteroarylmethyl)Phenyl)-Heteroarylamines |
| AU2160899A (en) | 1997-12-11 | 1999-06-28 | Janssen Pharmaceutica N.V. | Retinoic acid mimetic anilides |
| US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| DE19951701A1 (de) | 1999-10-27 | 2001-05-03 | Aventis Pharma Gmbh | Verwendung von 2-Imidazolyl-substituierten Carbinolen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten |
| US7780687B2 (en) * | 2002-04-17 | 2010-08-24 | Tyco Healthcare Group Lp | Method and apparatus for anastomosis including expandable anchor |
| JP2006507299A (ja) | 2002-10-30 | 2006-03-02 | メルク エンド カムパニー インコーポレーテッド | Ａｋｔ活性の阻害薬 |
| CA2522430A1 (en) | 2003-04-24 | 2004-11-11 | Merck & Co., Inc. | Inhibitors of akt activity |
| NZ544472A (en) * | 2003-07-03 | 2009-04-30 | Myriad Genetics Inc | Compounds and therapeutical use thereof |
| US8309562B2 (en) | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
| DE10337942A1 (de) * | 2003-08-18 | 2005-03-17 | Merck Patent Gmbh | Aminobenzimidazolderivate |
| NZ553341A (en) | 2004-09-24 | 2010-11-26 | Allergan Inc | 4-(phenylmethyl and substituted phenylmethyl)-imidazole-2-thiones acting as specific alpha2 adrenergic agonists |
| EP1791832A1 (en) | 2004-09-24 | 2007-06-06 | Allergan, Inc. | 4-(heteroaryl-methyl and substituted heteroaryl-methyl)-imidazole-2-thiones acting as alpha2 adrenergic agonists |
| MX2007003094A (es) * | 2004-09-24 | 2007-06-07 | Allergan Inc | 4-(metilo ciclico condensado)-imidazol-2-tionas como agonistas alfa2 adrenergicos. |
| MX2007003307A (es) * | 2004-09-28 | 2007-05-16 | Allergan Inc | 4-bencil-1,3-dihidro-imidazol-2-tionas substituidas y no substituidas que actuan como agonistas adrenergicos alfa2 especificos o selectivos y metodos de uso de las mismas. |
| US8258145B2 (en) | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
| CA2592900A1 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
| US7547782B2 (en) | 2005-09-30 | 2009-06-16 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| JP5685364B2 (ja) * | 2006-01-17 | 2015-03-18 | スティーフェル・ラボラトリーズ・インコーポレーテッド | トリアゾール化合物による炎症性疾患の処置 |
| CA2667053C (en) * | 2006-10-17 | 2015-04-28 | Stiefel Laboratories, Inc. | Talarazole metabolites |
| CN101827841B (zh) * | 2007-10-18 | 2012-11-28 | 多派股份公司 | (r)-4-(杂芳基)苯乙基衍生物及其药物组合物 |
| GB0811091D0 (en) * | 2008-06-17 | 2008-07-23 | Cancer Rec Tech Ltd | CYP26 Inhibitors |
| US10414760B2 (en) | 2016-11-29 | 2019-09-17 | Angion Biomedica Corp. | Cytochrome P450 inhibitors and uses thereof |
| AU2011261586B2 (en) | 2010-06-01 | 2015-08-27 | Angion Biomedica Corp. | Cytochrome P450 inhibitors and uses thereof |
| KR101108577B1 (ko) * | 2010-07-28 | 2012-01-30 | 국제엘렉트릭코리아 주식회사 | 테이프 히터 |
| RU2632900C2 (ru) | 2010-11-19 | 2017-10-11 | Лиганд Фармасьютикалс Инкорпорейтед | Гетероциклические амины и их применение |
| WO2013028771A1 (en) | 2011-08-23 | 2013-02-28 | Leong Hwei Xian | Reversing intestinal inflammation by inhibiting retinoic acid metabolism |
| ES2886641T3 (es) | 2014-08-11 | 2021-12-20 | Angion Biomedica Corp | Inhibidores de citocromo P450 y sus usos |
| CN107531631B (zh) | 2014-12-31 | 2021-09-03 | 安吉昂生物医药公司 | 用于治疗疾病的方法和药剂 |
| US10807983B2 (en) | 2015-03-16 | 2020-10-20 | Ligand Pharmaceuticals, Inc. | Imidazo-fused heterocycles and uses thereof |
| CN106588780A (zh) * | 2016-12-15 | 2017-04-26 | 青岛辰达生物科技有限公司 | 一种盐酸右美托咪定中间体的制备工艺 |
| CN106632051A (zh) * | 2016-12-15 | 2017-05-10 | 青岛辰达生物科技有限公司 | 一种盐酸右美托咪定中间体的合成方法 |
| CN106588779A (zh) * | 2016-12-15 | 2017-04-26 | 青岛辰达生物科技有限公司 | 一种合成盐酸右美托咪定中间体的方法 |
| KR20210055340A (ko) | 2019-11-07 | 2021-05-17 | 정화종 | 화물 커버 |
| CN115462347B (zh) * | 2021-08-13 | 2024-07-16 | 广州市妇女儿童医疗中心 | 视黄酸代谢通路在先天性巨结肠疾病中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ221729A (en) * | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
| CA2002859C (en) * | 1988-11-29 | 1998-12-29 | Jean P. F. Van Wauwe | Method of treating epithelial disorders |
| DK0482208T3 (da) | 1990-04-25 | 2000-09-18 | Nissan Chemical Ind Ltd | Pyridazinonderivat |
| TW321649B (bg) | 1994-11-12 | 1997-12-01 | Zeneca Ltd | |
| US5582832A (en) * | 1995-06-06 | 1996-12-10 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Compositions for topical application to skin |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| IL125686A (en) | 1996-02-13 | 2002-11-10 | Zeneca Ltd | Quinazoline derivatives, processes for their preparation, pharmaceutical preparations containing them and their use in the manufacture of a drug with an anti-angiogenic effect and / or an effect of reducing vascular permeability |
| US5731342A (en) * | 1996-02-22 | 1998-03-24 | Eli Lilly And Company | Benzothiophenes, formulations containing same, and methods |
| AU711575B2 (en) * | 1996-06-27 | 1999-10-14 | Janssen Pharmaceutica N.V. | N-(4-(Heteroarylmethyl)Phenyl)-Heteroarylamines |
-
1997
- 1997-06-19 AU AU34356/97A patent/AU711575B2/en not_active Expired
- 1997-06-19 WO PCT/EP1997/003248 patent/WO1997049704A1/en active IP Right Grant
- 1997-06-19 EP EP97930378A patent/EP0907650B1/en not_active Expired - Lifetime
- 1997-06-19 CZ CZ0423198A patent/CZ297769B6/cs not_active IP Right Cessation
- 1997-06-19 PT PT97930378T patent/PT907650E/pt unknown
- 1997-06-19 AT AT97930378T patent/ATE229019T1/de active
- 1997-06-19 PL PL330816A patent/PL201704B1/pl unknown
- 1997-06-19 DE DE69717627T patent/DE69717627T2/de not_active Expired - Lifetime
- 1997-06-19 TR TR1998/02709T patent/TR199802709T2/xx unknown
- 1997-06-19 KR KR10-1998-0709764A patent/KR100365312B1/ko not_active IP Right Cessation
- 1997-06-19 NZ NZ333382A patent/NZ333382A/xx not_active IP Right Cessation
- 1997-06-19 SK SK1781-98A patent/SK282769B6/sk not_active IP Right Cessation
- 1997-06-19 ES ES97930378T patent/ES2188957T3/es not_active Expired - Lifetime
- 1997-06-19 HU HU9902138A patent/HU223093B1/hu active IP Right Grant
- 1997-06-19 EE EE9800437A patent/EE03688B1/xx unknown
- 1997-06-19 CA CA002258165A patent/CA2258165C/en not_active Expired - Lifetime
- 1997-06-19 CN CN97195865A patent/CN1102593C/zh not_active Expired - Lifetime
- 1997-06-19 DK DK97930378T patent/DK0907650T3/da active
- 1997-06-19 JP JP50232198A patent/JP3404749B2/ja not_active Expired - Lifetime
- 1997-06-19 BR BR9710002A patent/BR9710002A/pt not_active IP Right Cessation
- 1997-06-19 SI SI9730478T patent/SI0907650T1/xx unknown
- 1997-06-19 UA UA98116146A patent/UA53649C2/uk unknown
- 1997-06-19 RU RU99101902/04A patent/RU2190611C2/ru active
- 1997-06-19 IL IL12774097A patent/IL127740A/en not_active IP Right Cessation
- 1997-06-19 US US09/214,080 patent/US6124330A/en not_active Expired - Lifetime
- 1997-06-23 TW TW086108726A patent/TW490464B/zh not_active IP Right Cessation
- 1997-06-25 MY MYPI97002859A patent/MY116917A/en unknown
- 1997-06-26 AR ARP970102822A patent/AR007626A1/es active IP Right Grant
- 1997-06-26 ZA ZA975698A patent/ZA975698B/xx unknown
- 1997-06-26 ID IDP972217A patent/ID17275A/id unknown
-
1998
- 1998-12-14 BG BG103013A patent/BG63545B1/bg unknown
- 1998-12-21 NO NO19986017A patent/NO312102B1/no not_active IP Right Cessation
-
1999
- 1999-08-16 HK HK99103546A patent/HK1018458A1/xx not_active IP Right Cessation
-
2000
- 2000-07-25 US US09/624,966 patent/US6486187B1/en not_active Expired - Lifetime
-
2002
- 2002-09-10 US US10/238,686 patent/US6833375B2/en not_active Expired - Lifetime
-
2004
- 2004-11-02 US US10/979,362 patent/US7205312B2/en not_active Expired - Fee Related
-
2006
- 2006-12-13 US US11/639,043 patent/US7378433B2/en not_active Expired - Fee Related
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