BG102623A - New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous forms - Google Patents
New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous formsInfo
- Publication number
- BG102623A BG102623A BG102623A BG10262398A BG102623A BG 102623 A BG102623 A BG 102623A BG 102623 A BG102623 A BG 102623A BG 10262398 A BG10262398 A BG 10262398A BG 102623 A BG102623 A BG 102623A
- Authority
- BG
- Bulgaria
- Prior art keywords
- benzoylguanadine
- manufacture
- methods
- application
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19601303A DE19601303A1 (de) | 1996-01-16 | 1996-01-16 | Neuartige Benzoylguanidin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Herstellung von Arzneimitteln |
PCT/EP1997/000177 WO1997026253A1 (fr) | 1996-01-16 | 1997-01-16 | Derives de benzoylguanidine d'un type nouveau, leur procede de preparation et leur utilisation pour la fabrication de medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
BG102623A true BG102623A (en) | 1999-03-31 |
Family
ID=7782846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG102623A Pending BG102623A (en) | 1996-01-16 | 1998-07-10 | New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous forms |
Country Status (27)
Country | Link |
---|---|
US (1) | US6114335A (fr) |
EP (1) | EP0882031A1 (fr) |
JP (1) | JP2000503309A (fr) |
KR (1) | KR19990077304A (fr) |
CN (1) | CN1072663C (fr) |
AR (1) | AR005468A1 (fr) |
AU (1) | AU722619B2 (fr) |
BG (1) | BG102623A (fr) |
BR (1) | BR9707002A (fr) |
CA (1) | CA2240075A1 (fr) |
CO (1) | CO4761058A1 (fr) |
CZ (1) | CZ225398A3 (fr) |
DE (1) | DE19601303A1 (fr) |
EE (1) | EE9800200A (fr) |
HK (1) | HK1016981A1 (fr) |
HU (1) | HUP9900584A3 (fr) |
IL (1) | IL124779A0 (fr) |
NO (1) | NO311517B1 (fr) |
NZ (1) | NZ326347A (fr) |
PL (1) | PL327854A1 (fr) |
RU (1) | RU2181720C2 (fr) |
SK (1) | SK282751B6 (fr) |
TR (1) | TR199801328T2 (fr) |
TW (1) | TW426673B (fr) |
UA (1) | UA48214C2 (fr) |
WO (1) | WO1997026253A1 (fr) |
ZA (1) | ZA97277B (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6323207B1 (en) * | 1998-09-22 | 2001-11-27 | Boehringer Ingelheim Pharma Kg | Benzoylguanidine derivatives |
DE19843489B4 (de) * | 1998-09-22 | 2006-12-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Benzoylguanidin-Abkömmlinge mit vorteilhaften Eigenschaften, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Herstellung von Arzneimitteln, sowie diese enthaltende pharmazeutische Zubereitung |
JP2000219674A (ja) * | 1999-01-29 | 2000-08-08 | Daiichi Radioisotope Labs Ltd | 新規アラルキルグアニジン化合物 |
ATE374609T1 (de) * | 2000-11-30 | 2007-10-15 | Childrens Medical Center | Synthese von 4-aminothalidomid enantiomeren |
IL147696A0 (en) * | 2001-01-25 | 2002-08-14 | Pfizer Prod Inc | Combination therapy |
DE10106970A1 (de) * | 2001-02-15 | 2002-08-29 | Boehringer Ingelheim Pharma | Neues Benzoylguanidinsalz |
US6730678B2 (en) * | 2001-02-15 | 2004-05-04 | Boehringer Ingelheim Pharma Kg | Benzoylguanidine salt and hydrates thereof |
DE10204989A1 (de) * | 2002-02-07 | 2003-08-21 | Aventis Pharma Gmbh | Dihydro-thia-phenanthren-carbonyl-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
US7323479B2 (en) * | 2002-05-17 | 2008-01-29 | Celgene Corporation | Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline |
UA83504C2 (en) * | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
KR20070057907A (ko) * | 2004-09-03 | 2007-06-07 | 셀진 코포레이션 | 치환된 2-(2,6-디옥소피페리딘-3-일)-1-옥소이소인돌린의제조 방법 |
ME01513B (me) | 2005-06-30 | 2014-04-20 | Celgene Corp | Postupak dobijanja spojeva 4-amin0-2-(2,6-dioksopiperidin-3-il)izoindolin-1,3-diona |
EP1962892A4 (fr) * | 2005-11-22 | 2011-10-12 | Univ South Florida | Inhibition de la proliferation de cellules |
US20080064876A1 (en) * | 2006-05-16 | 2008-03-13 | Muller George W | Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
CA2730116A1 (fr) * | 2008-07-08 | 2010-01-14 | Boehringer Ingelheim International Gmbh | Composes pyrrolidinylique et piperidinylique utiles comme inhibiteurs de nhe-1 |
US20100184851A1 (en) * | 2008-08-29 | 2010-07-22 | University Of South Florida | Inhibition of cell proliferation |
US9085551B2 (en) | 2012-02-21 | 2015-07-21 | Celgene Corporation | Solid forms of 3-(4-nitro-1-oxisoindolin-2-yl)piperidine-2,6-dione |
EP2815749A1 (fr) | 2013-06-20 | 2014-12-24 | IP Gesellschaft für Management mbH | Forme solide de 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione ayant un réseau de diffraction de rayons X spécifique |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2097409T3 (es) * | 1992-09-22 | 1997-04-01 | Hoechst Ag | Benzoilguanidinas, procedimiento para su preparacion, asi como su empleo como antiarritmicos. |
DE59309360D1 (de) * | 1992-12-02 | 1999-03-18 | Hoechst Ag | Guanidinalkyl-1, 1-bisphosphonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
TW250477B (fr) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
DE4337611A1 (de) * | 1993-11-04 | 1995-05-11 | Boehringer Ingelheim Kg | Neue Benzoylguanidine, ihre Herstellung und ihre Verwendung in Arzneimitteln |
DE4404183A1 (de) * | 1994-02-10 | 1995-08-17 | Merck Patent Gmbh | 4-Amino-1-piperidylbenzoylguanidine |
DE4430861A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
-
1996
- 1996-01-16 DE DE19601303A patent/DE19601303A1/de not_active Withdrawn
-
1997
- 1997-01-14 ZA ZA97277A patent/ZA97277B/xx unknown
- 1997-01-15 AR ARP970100146A patent/AR005468A1/es not_active Application Discontinuation
- 1997-01-15 CO CO97001473A patent/CO4761058A1/es unknown
- 1997-01-15 TW TW086100385A patent/TW426673B/zh not_active IP Right Cessation
- 1997-01-16 CZ CZ982253A patent/CZ225398A3/cs unknown
- 1997-01-16 WO PCT/EP1997/000177 patent/WO1997026253A1/fr not_active Application Discontinuation
- 1997-01-16 US US09/101,792 patent/US6114335A/en not_active Expired - Fee Related
- 1997-01-16 EP EP97901043A patent/EP0882031A1/fr not_active Withdrawn
- 1997-01-16 TR TR1998/01328T patent/TR199801328T2/xx unknown
- 1997-01-16 SK SK957-98A patent/SK282751B6/sk unknown
- 1997-01-16 HU HU9900584A patent/HUP9900584A3/hu unknown
- 1997-01-16 RU RU98115533/04A patent/RU2181720C2/ru not_active IP Right Cessation
- 1997-01-16 KR KR1019980705450A patent/KR19990077304A/ko not_active Application Discontinuation
- 1997-01-16 AU AU14429/97A patent/AU722619B2/en not_active Ceased
- 1997-01-16 IL IL12477997A patent/IL124779A0/xx unknown
- 1997-01-16 CN CN97191727A patent/CN1072663C/zh not_active Expired - Fee Related
- 1997-01-16 BR BR9707002A patent/BR9707002A/pt not_active IP Right Cessation
- 1997-01-16 EE EE9800200A patent/EE9800200A/xx unknown
- 1997-01-16 CA CA002240075A patent/CA2240075A1/fr not_active Abandoned
- 1997-01-16 JP JP9525687A patent/JP2000503309A/ja active Pending
- 1997-01-16 UA UA98084428A patent/UA48214C2/uk unknown
- 1997-01-16 NZ NZ326347A patent/NZ326347A/en unknown
- 1997-01-16 PL PL97327854A patent/PL327854A1/xx unknown
-
1998
- 1998-07-10 BG BG102623A patent/BG102623A/xx active Pending
- 1998-07-15 NO NO19983261A patent/NO311517B1/no not_active IP Right Cessation
-
1999
- 1999-05-13 HK HK99102143A patent/HK1016981A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EE9800200A (et) | 1998-12-15 |
KR19990077304A (ko) | 1999-10-25 |
NZ326347A (en) | 2001-03-30 |
UA48214C2 (uk) | 2002-08-15 |
BR9707002A (pt) | 1999-07-20 |
TR199801328T2 (xx) | 1998-10-21 |
TW426673B (en) | 2001-03-21 |
SK282751B6 (sk) | 2002-12-03 |
CN1072663C (zh) | 2001-10-10 |
CA2240075A1 (fr) | 1997-07-24 |
WO1997026253A1 (fr) | 1997-07-24 |
NO983261L (no) | 1998-07-15 |
CN1208409A (zh) | 1999-02-17 |
EP0882031A1 (fr) | 1998-12-09 |
JP2000503309A (ja) | 2000-03-21 |
DE19601303A1 (de) | 1997-07-17 |
CZ225398A3 (cs) | 1998-12-16 |
NO311517B1 (no) | 2001-12-03 |
HUP9900584A3 (en) | 2001-01-29 |
PL327854A1 (en) | 1999-01-04 |
RU2181720C2 (ru) | 2002-04-27 |
AU1442997A (en) | 1997-08-11 |
NO983261D0 (no) | 1998-07-15 |
AR005468A1 (es) | 1999-06-23 |
AU722619B2 (en) | 2000-08-10 |
ZA97277B (en) | 1997-07-16 |
CO4761058A1 (es) | 1999-04-27 |
IL124779A0 (en) | 1999-01-26 |
HK1016981A1 (en) | 1999-11-12 |
HUP9900584A2 (hu) | 1999-07-28 |
US6114335A (en) | 2000-09-05 |
SK95798A3 (en) | 1999-01-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BG102623A (en) | New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous forms | |
BG101132A (en) | Pyridoanilated thienyl and furanyl oxazolidinons | |
BG103251A (en) | Oxydiazols, methods for their preparation and application as medicamentous forms | |
MXPA02004666A (es) | Gelatinas recombinantes. | |
PL380081A1 (pl) | Pochodne 3,3-difenylopropyloamin, sposoby ich wytwarzania, kompozycja farmaceutyczna oraz zastosowania | |
BG107590A (en) | Synthetioc erythropoiesis stimulating proteins | |
PL336580A1 (en) | Fine-molecular compounds useful in treating inflammatory diseases | |
BG101139A (en) | Heteroatoms-containing cyclopentanopyridyloxazolidinons | |
HUP9802318A3 (en) | Phenylethanolamine derivatives, process for producing the same, and intermediates in the production of the same | |
MY131298A (en) | 5-heteroyl indole derivatives | |
PL323723A1 (en) | Novel derivatives of dolastatin, their production and application | |
EP0758247A4 (fr) | Derives d'heparine o-desulfatee leurs procedes de production et leurs utilisations | |
BG103914A (en) | Maintained separation of delayed gels | |
IS4945A (is) | Tilbúnar fjölsykrur, aðferð við að framleiða þær og lyfjablöndur sem innihalda þær | |
BG102362A (en) | New derivatives of amino acids, their preparation and application | |
AU5186799A (en) | Peptides of il-2 and derivatives thereof and their use as therapeutic agents | |
HUP9901616A3 (en) | Novel benzofuranone derivatives, process for their production and pharmaceutical compositions of the same | |
EP0911393A4 (fr) | Peptide, procede de production et mode d'utilisation correspondants | |
HRP20000480B1 (en) | Synthetic polysaccharides, their method of production and pharmaceutical compositions containing the same | |
BG102395A (en) | New phenylamidine derivatives, method for their preparation and application as medicamentous forms | |
BG102814A (en) | New derivatives of carboxylic acid, their preparation and application | |
BG104291A (en) | 3-substituted tetrahydropyridopyrimidinone derivatives, method for producing the same, and their use | |
MY107449A (en) | Bcrf1 proteins as inhibitors of interferon- gamma. | |
MY120550A (en) | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, processes for preparing them and their use as pharmaceutical compositions. | |
BG102707A (en) | New triazolopurinpurines, method for their preparation and appplication as medicamentous forms |