BE615194A - Process for the preparation of benzodiazepine derivatives - Google Patents

Process for the preparation of benzodiazepine derivatives

Info

Publication number
BE615194A
BE615194A BE615194A BE615194A BE615194A BE 615194 A BE615194 A BE 615194A BE 615194 A BE615194 A BE 615194A BE 615194 A BE615194 A BE 615194A BE 615194 A BE615194 A BE 615194A
Authority
BE
Belgium
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
BE615194A
Other languages
French (fr)
Inventor
Leo Henryk Sternbach
Arthur Stempel
George Sidney Sach
Gabriel Saucy
Franklin Artell Smith
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US114038A external-priority patent/US3153082A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BE615194A publication Critical patent/BE615194A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE615194A 1961-03-20 1962-03-16 Process for the preparation of benzodiazepine derivatives BE615194A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9666361A 1961-03-20 1961-03-20
US114038A US3153082A (en) 1961-06-01 1961-06-01 2-amino-benzophenones

Publications (1)

Publication Number Publication Date
BE615194A true BE615194A (en) 1962-09-17

Family

ID=26791934

Family Applications (1)

Application Number Title Priority Date Filing Date
BE615194A BE615194A (en) 1961-03-20 1962-03-16 Process for the preparation of benzodiazepine derivatives

Country Status (5)

Country Link
BE (1) BE615194A (en)
CH (2) CH445500A (en)
ES (1) ES275601A1 (en)
GB (2) GB985657A (en)
SE (1) SE301974B (en)

Also Published As

Publication number Publication date
SE301974B (en) 1968-07-01
GB985658A (en) 1965-03-10
DE1445858A1 (en) 1969-01-16
GB985657A (en) 1965-03-10
ES275601A1 (en) 1962-09-16
CH459239A (en) 1968-07-15
CH445500A (en) 1967-10-31
DE1445858B2 (en) 1975-07-03

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