AU7905194A - A medicinal aerosol formulation - Google Patents

A medicinal aerosol formulation

Info

Publication number
AU7905194A
AU7905194A AU79051/94A AU7905194A AU7905194A AU 7905194 A AU7905194 A AU 7905194A AU 79051/94 A AU79051/94 A AU 79051/94A AU 7905194 A AU7905194 A AU 7905194A AU 7905194 A AU7905194 A AU 7905194A
Authority
AU
Australia
Prior art keywords
aerosol formulation
medicinal aerosol
medicinal
formulation
aerosol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU79051/94A
Other versions
AU676390B2 (en
Inventor
Gunter Ditzinger
Wolfgang Zott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU7905194A publication Critical patent/AU7905194A/en
Application granted granted Critical
Publication of AU676390B2 publication Critical patent/AU676390B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU79051/94A 1993-11-27 1994-11-25 A medicinal aerosol formulation Ceased AU676390B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4340434 1993-11-27
DE4340434 1993-11-27

Publications (2)

Publication Number Publication Date
AU7905194A true AU7905194A (en) 1995-06-08
AU676390B2 AU676390B2 (en) 1997-03-06

Family

ID=6503581

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79051/94A Ceased AU676390B2 (en) 1993-11-27 1994-11-25 A medicinal aerosol formulation

Country Status (10)

Country Link
EP (1) EP0655237A1 (en)
JP (1) JPH07187996A (en)
KR (1) KR950013499A (en)
AU (1) AU676390B2 (en)
CA (1) CA2136704A1 (en)
FI (1) FI945524A (en)
HU (1) HUT75152A (en)
NO (1) NO944526L (en)
NZ (1) NZ264993A (en)
ZA (1) ZA949378B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605674A (en) * 1988-12-06 1997-02-25 Riker Laboratories, Inc. Medicinal aerosol formulations
US5766573A (en) * 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
US8933023B2 (en) 2004-03-12 2015-01-13 Biodel Inc. Rapid acting injectable insulin compositions

Families Citing this family (67)

* Cited by examiner, † Cited by third party
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US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
AU689217B2 (en) 1994-03-07 1998-03-26 Novartis Ag Methods and compositions for pulmonary delivery of insulin
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
GB9426252D0 (en) * 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
CZ292186B6 (en) * 1996-01-24 2003-08-13 Altana Pharma Ag Process for producing a pulverulent pulmonary surfactant preparation, the pulverulent pulmonary surfactant preparation per se and its use
EP0971698A4 (en) 1996-12-31 2006-07-26 Nektar Therapeutics Aerosolized hydrophobic drug
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
ES2195408T5 (en) * 1997-09-29 2010-11-25 Novartis Ag DUST FORMATION PROCEDURE THAT INCLUDES PERFORATED MICROPARTS.
PL343491A1 (en) * 1998-04-18 2001-08-27 Glaxo Group Ltd Pharmaceutical aerosol formulation
US6451349B1 (en) 1998-08-19 2002-09-17 Quadrant Healthcare (Uk) Limited Spray-drying process for the preparation of microparticles
EP1767195A3 (en) * 1998-08-25 2007-04-04 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
ES2289823T3 (en) * 1998-08-25 2008-02-01 Advanced Inhalation Research, Inc. STABLE PROTEIC FORMULATIONS DRIED BY ATOMIZATION.
DE60001492T2 (en) * 1999-04-14 2003-12-18 Glaxo Group Ltd., Greenford PHARMACEUTICAL AEROSOL FORMULATION
EP1642572A1 (en) * 1999-05-27 2006-04-05 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
AU768022B2 (en) * 1999-05-27 2003-11-27 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US7919119B2 (en) 1999-05-27 2011-04-05 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US6610317B2 (en) 1999-05-27 2003-08-26 Acusphere, Inc. Porous paclitaxel matrices and methods of manufacture thereof
US6395300B1 (en) 1999-05-27 2002-05-28 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
PT1808438E (en) 1999-06-29 2015-01-14 Mannkind Corp Purification and stabilization of peptide and proteins in pharmaceutical agents
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
PT1280520E (en) 2000-05-10 2014-12-16 Novartis Ag Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
GB0024271D0 (en) * 2000-09-25 2000-11-15 Colaco Camilo Improved methods and compositions for pulmonary delivery of actives
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
DK1458360T3 (en) 2001-12-19 2011-08-29 Novartis Ag Pulmonary release of aminoglycosides
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
JP4792457B2 (en) 2004-03-26 2011-10-12 ユニヴァーシタ’デグリ ステュディ ディ パルマ Highly breathable insulin microparticles
PL1786784T3 (en) 2004-08-20 2011-04-29 Mannkind Corp Catalysis of diketopiperazine synthesis
EP1791542B1 (en) 2004-08-23 2015-05-20 Mannkind Corporation Diketopiperazine salts for drug delivery
DK1928423T3 (en) 2005-09-14 2016-02-29 Mannkind Corp A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
RU2403059C2 (en) 2006-02-22 2010-11-10 Маннкайнд Корпорейшн Method of improving pharmaceutical properties of particles, containing diketopiperazine and active agent
MX2008013165A (en) 2006-04-12 2009-01-29 Biodel Inc Rapid acting and long acting insulin combination formulations.
DE102006030164A1 (en) * 2006-06-29 2008-01-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative powders
GB0621707D0 (en) * 2006-10-31 2006-12-13 Univ London Pharmacy Formulations for delivery via pressurised metered dose inhalers
US8148377B2 (en) 2007-02-11 2012-04-03 Map Pharmaceuticals, Inc. Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile
TWI611818B (en) 2008-06-13 2018-01-21 曼凱公司 A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (en) 2008-06-20 2014-04-23 マンカインド コーポレイション Interactive device and method for profiling inhalation efforts in real time
TWI494123B (en) 2008-08-11 2015-08-01 Mannkind Corp Use of ultrarapid acting insulin
BRPI0916047A2 (en) * 2008-11-04 2015-11-10 Cipla Ltd aerosol pharmaceutical composition, use of an aerosol pharmaceutical composition, method for treating severe, moderate or mild acute or chronic symptoms, or for prophylactic treatment of a respiratory disorder, aerosol pharmaceutical dispenser, process for manufacturing an aerosol pharmaceutical dispenser and process for making a complex of an active agent and an adjuvant
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CN102292072A (en) 2009-01-26 2011-12-21 特瓦制药工业有限公司 Processes for coating a carrier with microparticles
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
KR20130117755A (en) 2010-06-21 2013-10-28 맨카인드 코포레이션 Dry powder drug delivery system and methods
BR112013025395B1 (en) 2011-04-01 2022-02-01 Mannkind Corporation Blister packaging and manufacturing method of a bubble wrap
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CN108057154B (en) 2012-07-12 2021-04-16 曼金德公司 Dry powder drug delivery system and method
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
CN108578372B (en) 2013-03-15 2021-07-06 曼金德公司 Microcrystalline diketopiperazine compositions and methods
JP6491658B2 (en) 2013-07-18 2019-03-27 マンカインド コーポレイション Thermally stable dry powder pharmaceutical composition and method
CN105517607A (en) 2013-08-05 2016-04-20 曼金德公司 Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2081474A1 (en) * 1990-05-08 1991-11-09 Manzer Durrani Direct spray-dried drug/lipid powder composition
DE4123663A1 (en) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Medicinal aerosol free from fluoro:chlorocarbon(s) - contains active agent in suspending or dispersing aid and alcohol with hepta:fluoro:propane as propellant

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605674A (en) * 1988-12-06 1997-02-25 Riker Laboratories, Inc. Medicinal aerosol formulations
US5674473A (en) * 1988-12-06 1997-10-07 Riker Laboratories, Inc. Medicinal aerosol formulations
US5681545A (en) * 1988-12-06 1997-10-28 Riker Laboratories, Inc. Medicinal aerosol formulations
US5683677A (en) * 1988-12-06 1997-11-04 Riker Laboratories, Inc. Medicinal aerosol formulations
US5695743A (en) * 1988-12-06 1997-12-09 Riker Laboratories, Inc. Medicinal aerosol formulations
US5720940A (en) * 1988-12-06 1998-02-24 Riker Laboratories, Inc. Medicinal aerosol formulations
US5766573A (en) * 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
US5776434A (en) * 1988-12-06 1998-07-07 Riker Laboratories, Inc. Medicinal aerosol formulations
US6352684B1 (en) 1988-12-06 2002-03-05 Riker Laboratories Inc. CRC-free medicinal aerosol formulations of 1,1,1,2-tetrafluoroethane (134A) with polar adjuvant
US8933023B2 (en) 2004-03-12 2015-01-13 Biodel Inc. Rapid acting injectable insulin compositions

Also Published As

Publication number Publication date
CA2136704A1 (en) 1995-05-28
JPH07187996A (en) 1995-07-25
HU9403396D0 (en) 1995-02-28
NO944526L (en) 1995-05-29
KR950013499A (en) 1995-06-15
FI945524A (en) 1995-05-28
NZ264993A (en) 1996-03-26
HUT75152A (en) 1997-04-28
FI945524A0 (en) 1994-11-24
NO944526D0 (en) 1994-11-25
AU676390B2 (en) 1997-03-06
EP0655237A1 (en) 1995-05-31
ZA949378B (en) 1995-08-11

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired