AU738749B2 - Targeted cytotoxic cells - Google Patents

Targeted cytotoxic cells Download PDF

Info

Publication number
AU738749B2
AU738749B2 AU52394/98A AU5239498A AU738749B2 AU 738749 B2 AU738749 B2 AU 738749B2 AU 52394/98 A AU52394/98 A AU 52394/98A AU 5239498 A AU5239498 A AU 5239498A AU 738749 B2 AU738749 B2 AU 738749B2
Authority
AU
Australia
Prior art keywords
cell
immunotoxin
cells
antigen
cytotoxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU52394/98A
Other languages
English (en)
Other versions
AU5239498A (en
Inventor
Si-Yi Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wake Forest University
Original Assignee
Wake Forest University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wake Forest University filed Critical Wake Forest University
Publication of AU5239498A publication Critical patent/AU5239498A/en
Application granted granted Critical
Publication of AU738749B2 publication Critical patent/AU738749B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU52394/98A 1996-10-23 1997-10-23 Targeted cytotoxic cells Ceased AU738749B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74000396A 1996-10-23 1996-10-23
US08/740003 1996-10-23
PCT/US1997/019206 WO1998017116A1 (en) 1996-10-23 1997-10-23 Targeted cytotoxic cells

Publications (2)

Publication Number Publication Date
AU5239498A AU5239498A (en) 1998-05-15
AU738749B2 true AU738749B2 (en) 2001-09-27

Family

ID=24974660

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52394/98A Ceased AU738749B2 (en) 1996-10-23 1997-10-23 Targeted cytotoxic cells

Country Status (7)

Country Link
EP (1) EP0967878A4 (zh)
JP (1) JP2001503978A (zh)
CN (1) CN1244772A (zh)
AU (1) AU738749B2 (zh)
CA (1) CA2269507A1 (zh)
IL (1) IL129474A0 (zh)
WO (1) WO1998017116A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101542B1 (en) 1999-05-26 2006-09-05 Vallera Daniel A Cell-mediated targeting of toxins to pathogenic cells
ATE397087T1 (de) * 2000-08-08 2008-06-15 Mgvs Ltd Nukleinsäurekonstrukte, damit transformierte vaskuläre zellen, pharmezeutische zusammensetzungen und verfahren zur induktion der angiogenese
TW202115245A (zh) * 2019-06-27 2021-04-16 丹麥商諾佛 儂迪克股份有限公司 安全免疫隱形細胞

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012592A1 (en) * 1989-04-21 1990-11-01 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Recombinant antibody-toxin fusion protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10501681A (ja) * 1994-02-22 1998-02-17 ダナ−ファーバー キャンサー インスティチュート 核酸送達システムならびにその合成および使用方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012592A1 (en) * 1989-04-21 1990-11-01 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Recombinant antibody-toxin fusion protein

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN J EXP MED 1990 APR;60(2):57-65 *
PROTEIN ENG 1995 MAY;8(5):481-9 *

Also Published As

Publication number Publication date
WO1998017116A1 (en) 1998-04-30
CN1244772A (zh) 2000-02-16
EP0967878A4 (en) 2002-11-27
JP2001503978A (ja) 2001-03-27
AU5239498A (en) 1998-05-15
CA2269507A1 (en) 1998-04-30
EP0967878A1 (en) 2000-01-05
IL129474A0 (en) 2000-02-29

Similar Documents

Publication Publication Date Title
Chen et al. Potent antitumour activity of a new class of tumour-specific killer cells
US7186697B2 (en) Nucleic acid delivery system, methods of synthesis and use thereof
RU2198895C2 (ru) Конъюгат, обладающий способностью активировать иммунную систему, и фармацевтическая композиция, включающая указанный конъюгат
US7074909B2 (en) Antibodies
EP0279688B1 (en) Methods and compositions for the use of HIV env polypeptides and antibodies thereto
US20240075143A1 (en) Cd7-targeted engineered immune cell, chimeric antigen receptor, cd7 blocking molecule and use thereof
KR19990022644A (ko) 항-Fc 수용체 항체로 구성된 치료화합물
WO1992007574A1 (en) Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on b cells
US20070161080A1 (en) Antibodies
EP4149967A1 (en) Anti-bcma antibodies and chimeric antigen receptors
AU738749B2 (en) Targeted cytotoxic cells
Yang et al. A new class of antigen-specific killer cells
US20230181640A1 (en) Anti-bcma antibodies and chimeric antigen receptors
AU631674B2 (en) Pokeweed antiviral protein - monoclonal antibody conjugates
JP2813630B2 (ja) ヒト免疫不全ウイルスのエンベロープポリペプチドおよびその抗体
US20220298240A1 (en) Bispecific Chimeric Antigen Receptor
MXPA99003758A (en) Targeted cytotoxic cells

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired