AU616367B2 - Ginkgolide derivatives - Google Patents

Ginkgolide derivatives Download PDF

Info

Publication number
AU616367B2
AU616367B2 AU24644/88A AU2464488A AU616367B2 AU 616367 B2 AU616367 B2 AU 616367B2 AU 24644/88 A AU24644/88 A AU 24644/88A AU 2464488 A AU2464488 A AU 2464488A AU 616367 B2 AU616367 B2 AU 616367B2
Authority
AU
Australia
Prior art keywords
ginkgolide
alkoxy
mixture
ginkgolides
diazoalkane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU24644/88A
Other languages
English (en)
Other versions
AU2464488A (en
Inventor
Pierre Braquet
Andre Esanu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of AU2464488A publication Critical patent/AU2464488A/en
Application granted granted Critical
Publication of AU616367B2 publication Critical patent/AU616367B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
AU24644/88A 1987-11-04 1988-11-03 Ginkgolide derivatives Ceased AU616367B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8725871 1987-11-04
GB878725871A GB8725871D0 (en) 1987-11-04 1987-11-04 Ginkgolide derivatives

Publications (2)

Publication Number Publication Date
AU2464488A AU2464488A (en) 1989-05-25
AU616367B2 true AU616367B2 (en) 1991-10-24

Family

ID=10626449

Family Applications (1)

Application Number Title Priority Date Filing Date
AU24644/88A Ceased AU616367B2 (en) 1987-11-04 1988-11-03 Ginkgolide derivatives

Country Status (28)

Country Link
JP (1) JPH0686455B2 (nl)
KR (1) KR970005536B1 (nl)
AT (1) AT397097B (nl)
AU (1) AU616367B2 (nl)
BE (1) BE1003455A3 (nl)
CA (1) CA1303619C (nl)
CH (1) CH675583A5 (nl)
DE (1) DE3837550A1 (nl)
DK (1) DK612788A (nl)
ES (1) ES2009364A6 (nl)
FI (1) FI90081C (nl)
FR (2) FR2622448B1 (nl)
GB (2) GB8725871D0 (nl)
GR (1) GR1000264B (nl)
HK (1) HK53992A (nl)
IE (1) IE61541B1 (nl)
IN (1) IN173404B (nl)
IT (1) IT1227456B (nl)
MA (1) MA21423A1 (nl)
MY (1) MY103446A (nl)
NL (1) NL8802635A (nl)
NO (1) NO167739C (nl)
NZ (1) NZ226738A (nl)
PT (1) PT88924B (nl)
SE (1) SE8803931L (nl)
SG (1) SG48292G (nl)
TN (1) TNSN88118A1 (nl)
ZA (1) ZA888184B (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
EP0459432B1 (en) * 1990-06-01 2000-08-23 Korth, Ruth, Dr. med. Treatment of diseases with paf-antagonists and procedure for determining their efficacy
ATE221779T1 (de) * 1991-11-04 2002-08-15 Ruth-Maria Korth Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten
FR2763592B1 (fr) * 1997-05-20 1999-07-16 Sod Conseils Rech Applic Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant
FR2777280B1 (fr) * 1998-04-10 2001-04-20 Centre Nat Rech Scient Derives de ginkgolides, leur procede de preparation et compositions pharmaceutiques les contenant
CN106892930B (zh) 2015-12-18 2020-02-18 成都百裕金阁莱药业有限公司 银杏内酯b衍生物及其制备方法与应用
CN108383852B (zh) * 2017-12-25 2019-11-22 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备
CN108373474B (zh) * 2017-12-25 2020-06-09 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
DE3710921C2 (de) * 1986-10-21 1996-09-26 Korth Ruth Verwendung der Gingkolide BN 52020, BN 52021 und BN 52063 zur Behandlung von Arteriosklerose
DE3735525C2 (de) * 1987-10-20 1997-02-20 Korth Ruth Maria Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten

Also Published As

Publication number Publication date
AU2464488A (en) 1989-05-25
SE8803931L (sv) 1989-05-05
NO884900D0 (no) 1988-11-03
IE61541B1 (en) 1994-11-16
TNSN88118A1 (fr) 1990-07-10
GB8824859D0 (en) 1988-11-30
JPH0686455B2 (ja) 1994-11-02
FR2622584B1 (fr) 1992-01-10
DE3837550A1 (de) 1989-05-18
NO167739B (no) 1991-08-26
FI885046A (fi) 1989-05-05
PT88924A (pt) 1988-12-01
NO167739C (no) 1991-12-04
KR970005536B1 (ko) 1997-04-17
IT1227456B (it) 1991-04-11
CA1303619C (en) 1992-06-16
IE883315L (en) 1989-05-04
GB2211841B (en) 1991-01-16
BE1003455A3 (fr) 1992-03-31
NL8802635A (nl) 1989-06-01
ATA269688A (de) 1993-06-15
SE8803931D0 (sv) 1988-10-31
MA21423A1 (fr) 1989-07-01
IT8822493A0 (it) 1988-11-04
FR2622448A1 (fr) 1989-05-05
GR1000264B (el) 1992-05-12
DK612788A (da) 1989-05-05
AT397097B (de) 1994-01-25
KR890008156A (ko) 1989-07-10
FI90081B (fi) 1993-09-15
ES2009364A6 (es) 1989-09-16
HK53992A (en) 1992-07-30
CH675583A5 (nl) 1990-10-15
NO884900L (no) 1989-05-05
PT88924B (pt) 1993-01-29
DK612788D0 (da) 1988-11-03
FR2622448B1 (fr) 1992-01-10
JPH01151583A (ja) 1989-06-14
ZA888184B (en) 1989-07-26
SG48292G (en) 1992-06-12
FI90081C (fi) 1993-12-27
GB8725871D0 (en) 1987-12-09
MY103446A (en) 1993-06-30
NZ226738A (en) 1990-05-28
FR2622584A1 (fr) 1989-05-05
DE3837550C2 (nl) 1991-12-12
IN173404B (nl) 1994-04-30
FI885046A0 (fi) 1988-11-02
GB2211841A (en) 1989-07-12

Similar Documents

Publication Publication Date Title
AU616367B2 (en) Ginkgolide derivatives
CN107335049B (zh) 菊科类型环肽化合物作为cGAS-STING信号通路抑制剂的应用
EP0073616B1 (en) Marine organism extracts, their extraction and use
DE69017946T2 (de) Zellwachstum hemmende makrozyklische Lactone namens Combretastatin D-2.
JPH02167278A (ja) 細胞生長抑制物質
JPH02311496A (ja) ドラスタチン１５とその応用
KR100651650B1 (ko) 아위로부터 분리된 세스키테르펜 화합물을 포함하는 항암제 조성물
Stella et al. Enhancement of bioavailability of a hydrophobic amine antimalarial by formulation with oleic acid in a soft gelatin capsule
EP1124817B1 (en) Method of preparing delta-9-tetrahydrocannabinol esters
JPH0699436B2 (ja) パンクラチスタチン
EP0906317A1 (en) Novel water-soluble c-ring analogues of 20(s)-camptothecin
SA01220202B1 (ar) مثبطات إنزيم النسخ العكسي غير النيوكليوزيديه non transcriptase reverse nucleoside inhibitors
JP3639973B2 (ja) スポンギスタチン６
WO2021098593A1 (zh) 多硫代二酮哌嗪类化合物Secoemestrin C的制备方法及其用途
WO1993016698A1 (en) SUBSTITUTED FURO[3',4':6,7]INDOLIZINO[1,2-b]QUINOLINONES
US6051565A (en) Farnesyl-protein transferase inhibitors
ITMI941112A1 (it) Alcaloidi da mappia foetida, loro uso e formulazioni che li contengono
KR0127777B1 (ko) 유파티린으로 된 항위염 및 항궤양제
EP0847397B1 (en) water-soluble c-ring analogues of 20 (s)-camptothecin
US3930014A (en) Pharmaceutical compositions
Mutch Medicinal Kaolin in Food Poisoning
US4357334A (en) Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
FI87779C (fi) Framstaellningsfoerfarande av terapeutiskt aktiva oktahydroindeno/7,7a,1-bc/furan-2,3-derivat
Janaranjani et al. STANDARDIZATION AND ANALYTICAL EVALUATION OF SIDDHA POLY HERBAL FORMULATION-SIVAN VEMBU CHOORANAM
Poulev et al. A Radioimmunoassay for the Cholinesterase Inhibitory Alkaloid Galanthamine